ATE244718T1 - Verfahren zur herstellung von azabicyclische derivaten - Google Patents
Verfahren zur herstellung von azabicyclische derivatenInfo
- Publication number
- ATE244718T1 ATE244718T1 AT95920011T AT95920011T ATE244718T1 AT E244718 T1 ATE244718 T1 AT E244718T1 AT 95920011 T AT95920011 T AT 95920011T AT 95920011 T AT95920011 T AT 95920011T AT E244718 T1 ATE244718 T1 AT E244718T1
- Authority
- AT
- Austria
- Prior art keywords
- group
- formula
- image
- producing
- compound
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 125000006656 (C2-C4) alkenyl group Chemical group 0.000 abstract 1
- 125000006650 (C2-C4) alkynyl group Chemical group 0.000 abstract 1
- IOVCWXUNBOPUCH-UHFFFAOYSA-N Nitrous acid Chemical compound ON=O IOVCWXUNBOPUCH-UHFFFAOYSA-N 0.000 abstract 1
- 125000006575 electron-withdrawing group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Catalysts (AREA)
- Saccharide Compounds (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9409705A GB9409705D0 (en) | 1994-05-14 | 1994-05-14 | Novel compounds |
| PCT/EP1995/001757 WO1995031456A1 (en) | 1994-05-14 | 1995-05-09 | Process for the preparation of azabicyclic derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE244718T1 true ATE244718T1 (de) | 2003-07-15 |
Family
ID=10755162
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95920011T ATE244718T1 (de) | 1994-05-14 | 1995-05-09 | Verfahren zur herstellung von azabicyclische derivaten |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US5808075A (de) |
| EP (1) | EP0759921B1 (de) |
| JP (1) | JPH10500119A (de) |
| KR (1) | KR100340396B1 (de) |
| CN (3) | CN1048013C (de) |
| AT (1) | ATE244718T1 (de) |
| AU (1) | AU695838B2 (de) |
| BR (1) | BR9507659A (de) |
| CA (1) | CA2190278A1 (de) |
| CZ (1) | CZ334796A3 (de) |
| DE (1) | DE69531242T2 (de) |
| DK (1) | DK0759921T3 (de) |
| ES (1) | ES2202364T3 (de) |
| GB (1) | GB9409705D0 (de) |
| HU (1) | HU216629B (de) |
| NO (1) | NO964818L (de) |
| NZ (1) | NZ287038A (de) |
| PL (1) | PL178720B1 (de) |
| PT (1) | PT759921E (de) |
| WO (1) | WO1995031456A1 (de) |
| ZA (1) | ZA953877B (de) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9421472D0 (en) * | 1994-10-25 | 1994-12-07 | Smithkline Beecham Plc | Novel methods |
| AU751607B2 (en) * | 1995-07-29 | 2002-08-22 | Smithkline Beecham Plc | Method of treatment of dementia |
| GB9615628D0 (en) * | 1996-07-25 | 1996-09-04 | Smithkline Beecham Plc | Formulation |
| EP1009403A4 (de) * | 1997-04-11 | 2002-08-28 | Lilly Co Eli | Verfahren zur behandlung von schizophrenie |
| WO2006006071A1 (en) * | 2004-07-07 | 2006-01-19 | Pfizer Products Inc. | Resolution of an aryl-fused azapolycyclic compound |
| GB0428170D0 (en) * | 2004-12-23 | 2005-01-26 | Biopartners Ltd | Mono and Combination Therapy |
| JP2009506069A (ja) | 2005-08-26 | 2009-02-12 | ブレインセルス，インコーポレイティド | ムスカリン性受容体調節による神経発生 |
| EP2258359A3 (de) | 2005-08-26 | 2011-04-06 | Braincells, Inc. | Neurogenese durch Modulation des Muscarinrezeptors mit Sabcomelin |
| JP2009512711A (ja) | 2005-10-21 | 2009-03-26 | ブレインセルス，インコーポレイティド | Ｐｄｅ阻害による神経新生の調節 |
| EP2314289A1 (de) | 2005-10-31 | 2011-04-27 | Braincells, Inc. | Gaba-rezeptor-vermittelte modulation von neurogenese |
| US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
| AU2007249399A1 (en) | 2006-05-09 | 2007-11-22 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
| CA2651862A1 (en) | 2006-05-09 | 2007-11-22 | Braincells, Inc. | 5 ht receptor mediated neurogenesis |
| WO2008030651A1 (en) | 2006-09-08 | 2008-03-13 | Braincells, Inc. | Combinations containing a 4-acylaminopyridine derivative |
| US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
| US20100216805A1 (en) | 2009-02-25 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
| WO2026013563A1 (en) | 2024-07-09 | 2026-01-15 | Syremis Therapeutics Ltd. | New salt forms of sabcomeline |
| WO2026013570A1 (en) | 2024-07-09 | 2026-01-15 | Syremis Therapeutics Ltd. | New salt forms of sabcomeline |
| WO2026013573A1 (en) | 2024-07-09 | 2026-01-15 | Syremis Therapeutics Ltd. | New salt forms of sabcomeline |
| WO2026013566A1 (en) | 2024-07-09 | 2026-01-15 | Syremis Therapeutics Ltd. | New salt forms of sabcomeline |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3904632A (en) * | 1972-05-08 | 1975-09-09 | Hoffmann La Roche | (')-di-o-isopropylidene-2-keto-l-gulonates |
| FR2183565B1 (de) * | 1972-05-10 | 1975-12-26 | Cerm Cent Europ Rech Mauvernay | |
| CA1014958A (en) * | 1973-10-05 | 1977-08-02 | Jacques Moleyre | .alpha.-QUINUCLIDYLMETHYL PHENYL KETONES |
| US4598093A (en) * | 1982-09-07 | 1986-07-01 | Yoshitomi Pharmaceutical Industries, Ltd. | 4-amino-tetrahydro-2-naphthoic acid derivatives |
| ATE269330T1 (de) * | 1989-04-13 | 2004-07-15 | Beecham Group Plc | Chemische verbindungen |
| US5418240A (en) * | 1990-08-21 | 1995-05-23 | Novo Nordisk A/S | Heterocyclic compounds and their preparation and use |
| DK198590D0 (da) * | 1990-08-21 | 1990-08-21 | Novo Nordisk As | Heterocykliske forbindelser, deres fremstilling og anvendelse |
| MX9300875A (es) * | 1992-02-20 | 1993-08-31 | Smithkline Beecham Plc | Procedimiento para la preparacion de compuestos azabiciclicos. |
-
1994
- 1994-05-14 GB GB9409705A patent/GB9409705D0/en active Pending
-
1995
- 1995-05-09 CN CN95193952A patent/CN1048013C/zh not_active Expired - Fee Related
- 1995-05-09 CA CA002190278A patent/CA2190278A1/en not_active Abandoned
- 1995-05-09 DK DK95920011T patent/DK0759921T3/da active
- 1995-05-09 DE DE69531242T patent/DE69531242T2/de not_active Expired - Fee Related
- 1995-05-09 PT PT95920011T patent/PT759921E/pt unknown
- 1995-05-09 CZ CZ963347A patent/CZ334796A3/cs unknown
- 1995-05-09 HU HU9603145A patent/HU216629B/hu not_active IP Right Cessation
- 1995-05-09 WO PCT/EP1995/001757 patent/WO1995031456A1/en not_active Ceased
- 1995-05-09 AU AU25628/95A patent/AU695838B2/en not_active Ceased
- 1995-05-09 AT AT95920011T patent/ATE244718T1/de not_active IP Right Cessation
- 1995-05-09 ES ES95920011T patent/ES2202364T3/es not_active Expired - Lifetime
- 1995-05-09 NZ NZ287038A patent/NZ287038A/en unknown
- 1995-05-09 US US08/737,427 patent/US5808075A/en not_active Expired - Fee Related
- 1995-05-09 JP JP7529334A patent/JPH10500119A/ja not_active Ceased
- 1995-05-09 KR KR1019960706442A patent/KR100340396B1/ko not_active Expired - Fee Related
- 1995-05-09 EP EP95920011A patent/EP0759921B1/de not_active Expired - Lifetime
- 1995-05-09 PL PL95317210A patent/PL178720B1/pl not_active IP Right Cessation
- 1995-05-09 BR BR9507659A patent/BR9507659A/pt not_active Application Discontinuation
- 1995-05-12 US US08/439,616 patent/US5773619A/en not_active Expired - Fee Related
- 1995-05-12 ZA ZA953877A patent/ZA953877B/xx unknown
-
1996
- 1996-11-13 NO NO964818A patent/NO964818L/no unknown
-
1999
- 1999-03-13 CN CN99103925A patent/CN1108302C/zh not_active Expired - Fee Related
- 1999-03-13 CN CN99103926A patent/CN1104431C/zh not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU695838B2 (en) | 1998-08-20 |
| PL178720B1 (pl) | 2000-06-30 |
| NO964818L (no) | 1997-01-13 |
| ES2202364T3 (es) | 2004-04-01 |
| DE69531242T2 (de) | 2004-05-27 |
| ZA953877B (en) | 1996-03-07 |
| DK0759921T3 (da) | 2003-11-03 |
| CN1270170A (zh) | 2000-10-18 |
| US5773619A (en) | 1998-06-30 |
| CA2190278A1 (en) | 1995-11-23 |
| KR970703342A (ko) | 1997-07-03 |
| NZ287038A (en) | 1997-11-24 |
| HUT75309A (en) | 1997-05-28 |
| HU216629B (hu) | 1999-07-28 |
| HK1012367A1 (en) | 1999-07-30 |
| PL317210A1 (en) | 1997-03-17 |
| DE69531242D1 (de) | 2003-08-14 |
| NO964818D0 (no) | 1996-11-13 |
| CN1151743A (zh) | 1997-06-11 |
| GB9409705D0 (en) | 1994-07-06 |
| US5808075A (en) | 1998-09-15 |
| CN1048013C (zh) | 2000-01-05 |
| EP0759921A1 (de) | 1997-03-05 |
| EP0759921B1 (de) | 2003-07-09 |
| AU2562895A (en) | 1995-12-05 |
| KR100340396B1 (ko) | 2002-10-25 |
| PT759921E (pt) | 2003-11-28 |
| BR9507659A (pt) | 1997-10-07 |
| CN1108302C (zh) | 2003-05-14 |
| HU9603145D0 (en) | 1997-01-28 |
| CZ334796A3 (en) | 1997-07-16 |
| CN1104431C (zh) | 2003-04-02 |
| CN1232825A (zh) | 1999-10-27 |
| JPH10500119A (ja) | 1998-01-06 |
| WO1995031456A1 (en) | 1995-11-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0759921 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |