ATE241350T1 - Transdermale verabreichungsform von flurbiprofen - Google Patents

Transdermale verabreichungsform von flurbiprofen

Info

Publication number
ATE241350T1
ATE241350T1 AT96944404T AT96944404T ATE241350T1 AT E241350 T1 ATE241350 T1 AT E241350T1 AT 96944404 T AT96944404 T AT 96944404T AT 96944404 T AT96944404 T AT 96944404T AT E241350 T1 ATE241350 T1 AT E241350T1
Authority
AT
Austria
Prior art keywords
flurbiprofen
transdermal administration
administration form
transdermal
administration
Prior art date
Application number
AT96944404T
Other languages
English (en)
Inventor
Jochem J Effing
Eberhard A Gruhlke
Kristin J Godbey
Wolfgang Welsing
Original Assignee
Minnesota Mining & Mfg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Minnesota Mining & Mfg filed Critical Minnesota Mining & Mfg
Application granted granted Critical
Publication of ATE241350T1 publication Critical patent/ATE241350T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dermatology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT96944404T 1995-12-22 1996-12-16 Transdermale verabreichungsform von flurbiprofen ATE241350T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/577,482 US5702720A (en) 1995-12-22 1995-12-22 Transdermal device for the delivery of flurbiprofen
PCT/US1996/020006 WO1997023205A1 (en) 1995-12-22 1996-12-16 Transdermal device for the delivery of flurbiprofen

Publications (1)

Publication Number Publication Date
ATE241350T1 true ATE241350T1 (de) 2003-06-15

Family

ID=24308917

Family Applications (2)

Application Number Title Priority Date Filing Date
AT96944404T ATE241350T1 (de) 1995-12-22 1996-12-16 Transdermale verabreichungsform von flurbiprofen
AT96943807T ATE243031T1 (de) 1995-12-22 1996-12-19 Vorrichtung zur verabreichung eines arzneistoffes

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT96943807T ATE243031T1 (de) 1995-12-22 1996-12-19 Vorrichtung zur verabreichung eines arzneistoffes

Country Status (22)

Country Link
US (2) US5702720A (de)
EP (2) EP0869781B1 (de)
JP (2) JP2000503638A (de)
KR (2) KR19990076588A (de)
CN (2) CN1098071C (de)
AR (1) AR005163A1 (de)
AT (2) ATE241350T1 (de)
AU (2) AU701782B2 (de)
CA (2) CA2238400A1 (de)
CO (1) CO4810224A1 (de)
CZ (2) CZ197298A3 (de)
DE (2) DE69628448T2 (de)
HR (1) HRP960608B1 (de)
HU (1) HUP9901991A3 (de)
IL (2) IL124629A (de)
MX (2) MX9804871A (de)
MY (1) MY113685A (de)
NO (2) NO982613L (de)
NZ (2) NZ325659A (de)
TW (1) TW436298B (de)
WO (2) WO1997023205A1 (de)
ZA (1) ZA9610729B (de)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5252334A (en) * 1989-09-08 1993-10-12 Cygnus Therapeutic Systems Solid matrix system for transdermal drug delivery
JP3782834B2 (ja) * 1994-10-26 2006-06-07 株式会社トクホン 鎮痛抗炎症貼付剤
DE19830649C2 (de) * 1998-07-09 2003-04-10 Lohmann Therapie Syst Lts Topisches Pflaster mit nichtsteroidalen Antirheumatika mit Säuregruppe
DE19834496B4 (de) 1998-07-31 2004-02-26 Beiersdorf Ag Verbesserte Freisetzung von Ibuprofen aus Heißschmelzklebemassen in wirkstoffhaltigen Pflastern durch Zusatz von pharmazeutischen Hilfsstoffen und Verwendung von Hilfsstoffen zur Verbesserung der Freisetzung von Ibuprofen
DE19840191A1 (de) * 1998-09-03 2000-03-09 Lohmann Therapie Syst Lts Arzneistoffhaltiges Pflaster mit drei funktionalen Schichten
US7052714B1 (en) * 1999-10-13 2006-05-30 Senju Pharmaceutical Co., Ltd Ophthalmic adhesive preparations for percutaneous adsorption
US20020110585A1 (en) 1999-11-30 2002-08-15 Godbey Kristin J. Patch therapeutic agent delivery device having texturized backing
US6455067B1 (en) * 2000-05-24 2002-09-24 Sang-A Pharmaceutical Co., Ltd. Transdermal patch for nonsteroidal antiinflammatory drug(s)
DE10032537A1 (de) * 2000-07-05 2002-01-31 Labtec Gmbh Dermales System, enthaltend 2-(3-Benzophenyl)Propionsäure
DE10049225A1 (de) * 2000-09-28 2002-04-11 Labtec Gmbh Dermales System, enthaltend Diclofenac
AU2002235155A1 (en) * 2000-12-05 2002-06-18 Noven Pharmaceuticals, Inc. Crystallization inhibition of drugs in transdermal drug delivery systems
US7803392B2 (en) * 2000-12-27 2010-09-28 University Of Kentucky Research Foundation pH-Sensitive mucoadhesive film-forming gels and wax-film composites suitable for topical and mucosal delivery of molecules
US6479076B2 (en) * 2001-01-12 2002-11-12 Izhak Blank Nicotine delivery compositions
NZ530227A (en) * 2001-06-18 2006-09-29 Noven Pharma Enhanced drug delivery in transdermal systems
US6805878B2 (en) * 2001-09-13 2004-10-19 Noven Pharmaceuticals, Inc. Transdermal administration of ACE inhibitors
US6951642B2 (en) 2001-09-28 2005-10-04 3M Innovative Properties Company Water-in-oil emulsions with anionic groups, compositions, and methods
US7030203B2 (en) 2001-09-28 2006-04-18 3M Innovative Properties Company Water-in-oil emulsions with ethylene oxide groups, compositions, and methods
US20030124174A1 (en) * 2001-10-25 2003-07-03 Endo Pharmaceuticals, Inc Method for treating non-neuropathic pain
US20030152612A1 (en) * 2002-01-03 2003-08-14 Pugliese Peter T. Method and article to control cellulite
US6838078B2 (en) 2002-01-16 2005-01-04 3M Innovative Properties Company Film-forming compositions and methods
US7147873B2 (en) * 2002-01-16 2006-12-12 3M Innovative Properties Company Antiseptic compositions and methods
DE10212864B4 (de) * 2002-03-22 2005-12-22 Beiersdorf Ag Polymermatrizes umfassend ein Mischsystem zur Löslichkeitsvermittlung von pharmazeutischen Wirkstoffen, Verfahren zu deren Herstellung und deren Verwendung
KR100517101B1 (ko) * 2002-07-31 2005-09-27 한국과학기술연구원 이중 자극 응답성 하이드로젤 및 이의 제조 방법
US20040062794A1 (en) * 2002-09-30 2004-04-01 Lee Shulman 17Beta- estradiol/levonorgestrel transdermal patch for hormone replacement therapy
WO2004080441A1 (ja) * 2003-03-10 2004-09-23 Tokuyama Corporation イオン性薬剤投与用の貼付材
AU2004249295A1 (en) * 2003-06-20 2004-12-29 Viral Genomix, Inc. Compositions for and methods for treating HIV
US20050065062A1 (en) * 2003-09-24 2005-03-24 3M Innovative Properties Company Method of formulating a pharmaceutical composition
GB2429651C (en) * 2004-02-17 2009-03-25 Cook Biotech Inc Medical devices and methods useful for applying bolster material
WO2006044206A2 (en) 2004-10-08 2006-04-27 Noven Pharmaceuticals, Inc. Transdermal drug delivery device including an occlusive backing
CA2586871C (en) * 2004-11-05 2012-03-13 Lead Chemical Co., Ltd. Nonaqueous preparation for percutaneous absorption containing nonsteroidal anti-inflammatory analgesic
KR100663163B1 (ko) 2005-10-24 2007-01-02 (주)아모레퍼시픽 비스테로이드성 소염진통제를 함유하는 경피 투여 제제
EP2046307A2 (de) * 2006-06-14 2009-04-15 Arrow Coated Products Limited Vorrichtung zur verabreichung von wirkstoffen an menschen, tiere und pflanzen
KR20080006960A (ko) * 2006-07-14 2008-01-17 (주)아모레퍼시픽 소수성 비스테로이드성 소염진통제를 함유하는 경피 투여제제
US20080039415A1 (en) * 2006-08-11 2008-02-14 Gregory Robert Stewart Retrograde transport of sirna and therapeutic uses to treat neurologic disorders
JP5214223B2 (ja) * 2007-11-15 2013-06-19 船井電機株式会社 プロジェクタ
CA2709808A1 (en) * 2008-05-21 2009-11-26 Teikoku Pharma Usa, Inc. Treatment of dysmenorrhea via transdermal administration of nonsteroidal anti-inflammatory drugs
WO2010077096A2 (ko) * 2008-12-31 2010-07-08 한올바이오파마주식회사 약물전달기구
US20100291182A1 (en) * 2009-01-21 2010-11-18 Arsenal Medical, Inc. Drug-Loaded Fibers
US9682512B2 (en) 2009-02-06 2017-06-20 Nike, Inc. Methods of joining textiles and other elements incorporating a thermoplastic polymer material
US20100199520A1 (en) * 2009-02-06 2010-08-12 Nike, Inc. Textured Thermoplastic Non-Woven Elements
US20100199406A1 (en) 2009-02-06 2010-08-12 Nike, Inc. Thermoplastic Non-Woven Textile Elements
US8850719B2 (en) 2009-02-06 2014-10-07 Nike, Inc. Layered thermoplastic non-woven textile elements
US8906275B2 (en) 2012-05-29 2014-12-09 Nike, Inc. Textured elements incorporating non-woven textile materials and methods for manufacturing the textured elements
CN101502499B (zh) * 2009-03-13 2011-07-27 北京化工大学 一种布洛芬经皮释放贴剂及其制备方法
US9044580B2 (en) 2009-08-24 2015-06-02 Arsenal Medical, Inc. In-situ forming foams with outer layer
US9173817B2 (en) 2009-08-24 2015-11-03 Arsenal Medical, Inc. In situ forming hemostatic foam implants
US10420862B2 (en) 2009-08-24 2019-09-24 Aresenal AAA, LLC. In-situ forming foams for treatment of aneurysms
US20110202016A1 (en) * 2009-08-24 2011-08-18 Arsenal Medical, Inc. Systems and methods relating to polymer foams
BR112012012348A2 (pt) * 2009-11-23 2016-04-26 Isp Investments Inc solução reativa de polímeros polimerizáveis compreendedo funcionalidades reativas polimerizáveis, processos e composições da mesma
US9034240B2 (en) 2011-01-31 2015-05-19 Arsenal Medical, Inc. Electrospinning process for fiber manufacture
US9194058B2 (en) 2011-01-31 2015-11-24 Arsenal Medical, Inc. Electrospinning process for manufacture of multi-layered structures
US8968626B2 (en) 2011-01-31 2015-03-03 Arsenal Medical, Inc. Electrospinning process for manufacture of multi-layered structures
US8993831B2 (en) 2011-11-01 2015-03-31 Arsenal Medical, Inc. Foam and delivery system for treatment of postpartum hemorrhage
US20130255103A1 (en) 2012-04-03 2013-10-03 Nike, Inc. Apparel And Other Products Incorporating A Thermoplastic Polymer Material
ITMI20121428A1 (it) * 2012-08-10 2014-02-11 Allergosystem S R L Dispositivo per applicazione topica di medicamenti o cosmetici
KR20160106181A (ko) * 2014-01-29 2016-09-09 닛토덴코 가부시키가이샤 피부 투과 촉진 조성물, 경피 투여 제제 및 첩부 제제
US10195374B2 (en) 2014-05-07 2019-02-05 Boehringer Ingelheim International Gmbh Container, nebulizer and use
WO2018074261A1 (ja) * 2016-10-17 2018-04-26 第一三共株式会社 封入容器の製造方法及び製造装置
JP7069042B2 (ja) 2016-12-28 2022-05-17 久光製薬株式会社 貼付剤
US11872320B2 (en) 2021-02-25 2024-01-16 Hisamitsu Pharmaceutical Co., Inc. Method for treating osteoarthritis
CN116270575A (zh) * 2021-08-16 2023-06-23 乐明药业(苏州)有限公司 一种含有氟比洛芬的药物组合物与贴剂
WO2024145323A1 (en) * 2022-12-28 2024-07-04 Corium, Llc Pre-mixing method of preparing transdermal delivery system
WO2024145319A1 (en) * 2022-12-28 2024-07-04 Corium, Llc Method of preparing transdermal delivery system

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US24906A (en) * 1859-07-26 Simeon goodfellow
IT610737A (de) * 1955-11-18 1900-01-01
US3949128A (en) * 1972-08-22 1976-04-06 Kimberly-Clark Corporation Product and process for producing a stretchable nonwoven material from a spot bonded continuous filament web
US4185100A (en) * 1976-05-13 1980-01-22 Johnson & Johnson Topical anti-inflammatory drug therapy
JPS55139313A (en) * 1979-04-16 1980-10-31 Ota Seiyaku Kk Gel cream composition comprising higher fatty acid ethanol amide, and drug containing it
GB2075837B (en) * 1980-05-14 1984-03-14 Hisamitsu Pharmaceutical Co Topical pharmaceutical gel containing anti-inflammatory analgesic agents
US5445604A (en) * 1980-05-22 1995-08-29 Smith & Nephew Associated Companies, Ltd. Wound dressing with conformable elastomeric wound contact layer
JPS5855411A (ja) * 1981-09-28 1983-04-01 Nitto Electric Ind Co Ltd 基剤組成物および外用医薬組成物
US4473584A (en) * 1982-12-06 1984-09-25 The Upjohn Company Treatment of Type I Herpes virus with flurbiprofen
US4701470A (en) * 1982-12-06 1987-10-20 The Upjohn Company Treatment of Type II Herpes virus with ibuprofen
US4477468A (en) * 1982-12-06 1984-10-16 The Upjohn Company Treatment of type II herpes virus with flurbiprofen
JPS59222409A (ja) * 1983-06-01 1984-12-14 Nippon Redarii Kk 消炎鎮痛ゲル軟膏剤
CH662944A5 (it) * 1984-10-18 1987-11-13 Pier Luigi Prof Dr Luisi Procedimento per la preparazione di biocompatibili di micelle inverse di biocompatibili e loro utilizzazione.
US4751087A (en) * 1985-04-19 1988-06-14 Riker Laboratories, Inc. Transdermal nitroglycerin delivery system
DE3522550A1 (de) * 1985-06-24 1987-01-02 Klinge Co Chem Pharm Fab Aufspruehbare pharmazeutische zubereitung fuer die topische anwendung
DE3532562A1 (de) * 1985-09-12 1987-03-12 Dolorgiet Gmbh & Co Kg Transdermal resorbierbare, wasserhaltige zubereitungen von arylpropionsaeurederivaten und verfahren zur herstellung derselben
GB8701392D0 (en) * 1987-01-22 1987-02-25 Boots Co Plc Therapeutic agents
US5656286A (en) * 1988-03-04 1997-08-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
GB2217595B (en) * 1988-04-21 1991-11-20 American Cyanamid Co Antiinflammatory gel
US5230701A (en) * 1988-05-13 1993-07-27 Minnesota Mining And Manufacturing Company Elastomeric adhesive and cohesive materials
US5266723A (en) * 1989-05-16 1993-11-30 Medice, Ltd., Chem.-Pharm. Fabrik Putter Gmbh & Co. Kg Process for the preparation of optically active 2-aryl-alkanoic acids, especially 2-aryl-propionic acids
AU6758990A (en) * 1989-11-06 1991-05-31 Sepracor, Inc. Analgesic composition containing optically pure s(+) flurbiprofen
US5093133A (en) * 1990-01-24 1992-03-03 Mcneil-Ppc, Inc. Method for percutaneous delivery of ibuprofen using hydroalcoholic gel
WO1991017740A1 (en) * 1990-05-18 1991-11-28 Analgesic Associates Prevention or treatment of sunburn using the s(+) isomer of flurbiprofen
DE4028906A1 (de) * 1990-09-12 1992-03-19 Paz Arzneimittelentwicklung Arzneimittel sowie deren herstellung und deren verwendung bei der bekaempfung von schmerzen und/oder entzuendungen und/oder fieber an tieren und menschen
TW218849B (de) * 1991-05-17 1994-01-11 Bristol Myers Squibb Co
ATE176153T1 (de) * 1991-08-30 1999-02-15 Hisamitsu Pharmaceutical Co Entzündungshemmendes, analgetisches pflaster
DE4210711A1 (de) * 1991-10-31 1993-05-06 Schering Ag Berlin Und Bergkamen, 1000 Berlin, De Transdermale therapeutische systeme mit kristallisationsinhibitoren
GB2273044B (en) * 1992-12-02 1997-04-09 Pacific Chem Co Ltd Medicinal patches for percutaneous administration
AU6635294A (en) * 1993-04-22 1994-11-08 Minnesota Mining And Manufacturing Company Transdermal antiinflammatory composition

Also Published As

Publication number Publication date
CN1205631A (zh) 1999-01-20
HRP960608B1 (en) 2001-12-31
AU714798B2 (en) 2000-01-13
WO1997023206A1 (en) 1997-07-03
DE69628762D1 (de) 2003-07-24
HUP9901991A2 (hu) 1999-10-28
IL124804A0 (en) 1999-01-26
CA2238400A1 (en) 1997-07-03
MY113685A (en) 2002-04-30
NO982764L (no) 1998-06-15
HRP960608A2 (en) 1997-10-31
AU1295097A (en) 1997-07-17
ATE243031T1 (de) 2003-07-15
KR19990076589A (ko) 1999-10-15
DE69628762T2 (de) 2004-04-29
IL124629A0 (en) 1998-12-06
IL124804A (en) 2001-12-23
HUP9901991A3 (en) 2001-04-28
CO4810224A1 (es) 1999-06-30
AR005163A1 (es) 1999-04-14
NZ325659A (en) 2000-02-28
DE69628448D1 (de) 2003-07-03
CZ197198A3 (cs) 1998-11-11
JP2000502349A (ja) 2000-02-29
NO982764D0 (no) 1998-06-15
US5702720A (en) 1997-12-30
KR100452001B1 (ko) 2004-12-30
MX9804969A (es) 1998-09-30
JP2000503638A (ja) 2000-03-28
AU701782B2 (en) 1999-02-04
CN1098069C (zh) 2003-01-08
EP0869781B1 (de) 2003-05-28
KR19990076588A (ko) 1999-10-15
CZ197298A3 (cs) 1999-01-13
MX9804871A (es) 1998-10-31
DE69628448T2 (de) 2004-04-08
US6086911A (en) 2000-07-11
TW436298B (en) 2001-05-28
EP0868177B1 (de) 2003-06-18
CN1205630A (zh) 1999-01-20
WO1997023205A1 (en) 1997-07-03
AU1422097A (en) 1997-07-17
EP0868177A1 (de) 1998-10-07
IL124629A (en) 2001-10-31
NO982613D0 (no) 1998-06-05
EP0869781A1 (de) 1998-10-14
CN1098071C (zh) 2003-01-08
NO982613L (no) 1998-08-21
NZ325125A (en) 2000-05-26
ZA9610729B (en) 1998-06-19
CA2240349A1 (en) 1997-07-03

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