ATE237138T1 - Durch gruppen erweiterte fluorophore polymere, die eine hydrophobe und konformativ eingeschrankte mikroumgebung schaffen - Google Patents

Durch gruppen erweiterte fluorophore polymere, die eine hydrophobe und konformativ eingeschrankte mikroumgebung schaffen

Info

Publication number
ATE237138T1
ATE237138T1 AT97904060T AT97904060T ATE237138T1 AT E237138 T1 ATE237138 T1 AT E237138T1 AT 97904060 T AT97904060 T AT 97904060T AT 97904060 T AT97904060 T AT 97904060T AT E237138 T1 ATE237138 T1 AT E237138T1
Authority
AT
Austria
Prior art keywords
hydrophobic
groups
conformatively
fluorophore
create
Prior art date
Application number
AT97904060T
Other languages
German (de)
English (en)
Inventor
Christopher Bieniarz
Jeffrey B Huff
Michael J Cornwell
Venkata Seshagiri R Tata
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of ATE237138T1 publication Critical patent/ATE237138T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B69/00—Dyes not provided for by a single group of this subclass
    • C09B69/10—Polymeric dyes; Reaction products of dyes with monomers or with macromolecular compounds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/80—Fluorescent dyes, e.g. rhodamine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/141111—Diverse hetero atoms in same or different rings [e.g., alkaloids, opiates, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/17—Nitrogen containing
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/18—Sulfur containing

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Materials For Medical Uses (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
AT97904060T 1996-02-01 1997-01-30 Durch gruppen erweiterte fluorophore polymere, die eine hydrophobe und konformativ eingeschrankte mikroumgebung schaffen ATE237138T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/595,092 US5994143A (en) 1996-02-01 1996-02-01 Polymeric fluorophores enhanced by moieties providing a hydrophobic and conformationally restrictive microenvironment
PCT/US1997/001429 WO1997028447A1 (en) 1996-02-01 1997-01-30 Polymeric fluorophores enhanced by moieties providing a hydrophobic and conformationally restrictive microenvironment

Publications (1)

Publication Number Publication Date
ATE237138T1 true ATE237138T1 (de) 2003-04-15

Family

ID=24381697

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97904060T ATE237138T1 (de) 1996-02-01 1997-01-30 Durch gruppen erweiterte fluorophore polymere, die eine hydrophobe und konformativ eingeschrankte mikroumgebung schaffen

Country Status (7)

Country Link
US (1) US5994143A (cg-RX-API-DMAC7.html)
EP (1) EP1019722B1 (cg-RX-API-DMAC7.html)
JP (1) JP4255514B2 (cg-RX-API-DMAC7.html)
AT (1) ATE237138T1 (cg-RX-API-DMAC7.html)
DE (1) DE69720809T2 (cg-RX-API-DMAC7.html)
ES (1) ES2197332T3 (cg-RX-API-DMAC7.html)
WO (1) WO1997028447A1 (cg-RX-API-DMAC7.html)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6437099B1 (en) * 1998-01-07 2002-08-20 Hamamatsu Photonics K.K. Fluorescene—activating antisera and IgG fraction therefrom
JP3437094B2 (ja) * 1998-07-03 2003-08-18 松下電器産業株式会社 多波長蛍光偏光法
US20050069962A1 (en) * 2001-10-12 2005-03-31 Archer Robert M Antibody complexes and methods for immunolabeling
US8323903B2 (en) * 2001-10-12 2012-12-04 Life Technologies Corporation Antibody complexes and methods for immunolabeling
DE10331093A1 (de) * 2003-07-09 2005-02-10 Schering Ag Vorrichtung und Verfahren zur direkten quantitativen in vitro-Bestimmung einer in einer Probe enthaltenen Substanz
US20050233465A1 (en) * 2004-04-14 2005-10-20 Bioprocessors Corp. Compositions of matter useful as pH indicators and related methods
DE102004033050A1 (de) * 2004-07-08 2006-01-26 International University Bremen Gmbh Photostabilisierung von Fluoreszenzfarbstoffen
WO2007053594A2 (en) * 2005-10-31 2007-05-10 Clontech Laboratories, Inc. Large dynamic range proteomic analysis methods and compositions for practicing the same
US7781187B2 (en) * 2005-12-30 2010-08-24 Corning Incorporated Fluorescent dyes
GB2437545B (en) * 2006-04-28 2011-07-06 Novexin Ltd Dextrin-containing reagents for detecting and quantifying proteins
JP2013040136A (ja) * 2011-08-17 2013-02-28 Tosoh Corp ４−アルコキシ−２−（４−アミノスチリル）ベンゾチアゾリウム塩、その製造方法およびそれを用いる核酸の検出方法
CN105377994B (zh) 2013-08-22 2018-03-02 索尼公司 水溶性荧光染料或有色染料及其使用方法
CN103525117A (zh) * 2013-10-30 2014-01-22 苏州大学 一种半花菁荧光染料、制备方法及应用
WO2016021883A1 (ko) * 2014-08-02 2016-02-11 주식회사 엘지화학 염료 복합체, 광전환 필름, 및 이를 포함하는 전자소자
EP3262055A4 (en) 2015-02-26 2018-09-05 Sony Corporation Water soluble fluorescent or colored dyes comprising conjugating groups
CN104788991B (zh) * 2015-03-04 2017-01-25 苏州大学 一种二氯三嗪反应基半花菁荧光活性染料及其制备方法
EP3436528B1 (en) 2016-04-01 2025-07-02 Sony Group Corporation Ultra bright dimeric or polymeric dyes with rigid spacing groups
KR20250029292A (ko) 2016-04-01 2025-03-04 소니그룹주식회사 초휘도 이량체성 또는 중합체성 염료
US9851359B2 (en) 2016-04-06 2017-12-26 Sony Corporation Of America Ultra bright dimeric or polymeric dyes with spacing linker groups
US11390754B2 (en) * 2016-05-10 2022-07-19 Sony Corporation Compositions comprising a polymeric dye and a cyclodextrin and uses thereof
JP7527537B2 (ja) 2016-05-10 2024-08-05 ソニーグループ株式会社 ペプチド骨格を有する超明色ポリマー染料
KR102526802B1 (ko) * 2016-05-11 2023-05-02 소니그룹주식회사 초고명도 이량체성 또는 중합체성 염료
EP3464477A1 (en) 2016-06-06 2019-04-10 Sony Corporation Ionic polymers comprising fluorescent or colored reporter groups
US12018159B2 (en) 2016-07-29 2024-06-25 Sony Group Corporation Ultra bright dimeric or polymeric dyes and methods for preparation of the same
US12290571B2 (en) 2017-10-05 2025-05-06 Sony Group Corporation Programmable dendritic drugs
US12145956B2 (en) 2017-10-05 2024-11-19 Sony Group Corporation Programmable polymeric drugs
WO2019099789A1 (en) 2017-11-16 2019-05-23 Sony Corporation Programmable polymeric drugs
WO2019140227A1 (en) 2018-01-12 2019-07-18 Sony Corporation Phosphoalkyl ribose polymers comprising biologically active compounds
US12076407B2 (en) 2018-01-12 2024-09-03 Sony Group Corporation Polymers with rigid spacing groups comprising biologically active compounds
WO2019182765A1 (en) 2018-03-19 2019-09-26 Sony Corporation Use of divalent metals for enhancement of fluorescent signals
JP7515786B2 (ja) 2018-03-21 2024-07-16 ソニーグループ株式会社 リンカー基を有するポリマータンデム色素
WO2020006285A1 (en) 2018-06-27 2020-01-02 Sony Corporation Polymeric dyes with linker groups comprising deoxyribose
KR102718543B1 (ko) 2019-09-26 2024-10-18 소니그룹주식회사 링커 그룹을 갖는 중합체성 탠덤 염료
CN111500110B (zh) * 2020-04-28 2022-09-06 陕西大风印务科技有限公司 烟用包装纸用透明油墨及其涂层、烟用包装纸
US20240132725A1 (en) 2020-12-07 2024-04-25 Sony Group Corporation Spacing linker group design for brightness enhancement in dimeric or polymeric dyes

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4619990A (en) * 1985-03-11 1986-10-28 Minnesota Mining And Manufacturing Company Polymeric dyes with pendent chromophore groups capable of undergoing thermoplastic deformation
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4683195A (en) * 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US5002883A (en) * 1987-10-30 1991-03-26 Abbott Laboratories Covalent attachment of antibodies and antigens to solid phases using extended length heterobifunctional coupling agents
CA1323293C (en) * 1987-12-11 1993-10-19 Keith C. Backman Assay using template-dependent nucleic acid probe reorganization
DE3921498A1 (de) * 1988-09-28 1990-03-29 Bayer Ag Polymer-gebundene-farbstoffe, verfahren zu deren herstellung und verwendung
US5401469A (en) * 1989-04-19 1995-03-28 Ibiden Co., Ltd. Plastic optical biomaterials assay device
EP0439182B1 (en) * 1990-01-26 1996-04-24 Abbott Laboratories Improved method of amplifying target nucleic acids applicable to both polymerase and ligase chain reactions
US5401847A (en) * 1990-03-14 1995-03-28 Regents Of The University Of California DNA complexes with dyes designed for energy transfer as fluorescent markers
DE4114482A1 (de) * 1991-05-03 1992-11-05 Bayer Ag Polymere farbstoffe, verfahren zu deren herstellung und deren verwendung
WO1992020746A1 (en) * 1991-05-14 1992-11-26 Hybritech, Incorporated Polymeric compositions having bound antibodies
WO1995002700A1 (en) * 1993-07-13 1995-01-26 Abbott Laboratories Fluorescent polymer labeled conjugates and intermediates

Also Published As

Publication number Publication date
JP2000509412A (ja) 2000-07-25
DE69720809D1 (de) 2003-05-15
JP4255514B2 (ja) 2009-04-15
EP1019722B1 (en) 2003-04-09
US5994143A (en) 1999-11-30
WO1997028447A1 (en) 1997-08-07
EP1019722A1 (en) 2000-07-19
ES2197332T3 (es) 2004-01-01
DE69720809T2 (de) 2004-04-01

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