ATE235901T1 - Pharmazeutische zusammensetzung enthaltend 3-(2,2,2-trimethylhydrazinium)proprionat und gamma- butyrobetain für die behandlung von herz-gefäss- erkrankungen - Google Patents
Pharmazeutische zusammensetzung enthaltend 3-(2,2,2-trimethylhydrazinium)proprionat und gamma- butyrobetain für die behandlung von herz-gefäss- erkrankungenInfo
- Publication number
- ATE235901T1 ATE235901T1 AT96927931T AT96927931T ATE235901T1 AT E235901 T1 ATE235901 T1 AT E235901T1 AT 96927931 T AT96927931 T AT 96927931T AT 96927931 T AT96927931 T AT 96927931T AT E235901 T1 ATE235901 T1 AT E235901T1
- Authority
- AT
- Austria
- Prior art keywords
- pct
- trimethylhydrazinium
- gamma
- treatment
- pharmaceutical composition
- Prior art date
Links
- 208000024172 Cardiovascular disease Diseases 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- JHPNVNIEXXLNTR-UHFFFAOYSA-N 4-(trimethylammonio)butanoate Chemical compound C[N+](C)(C)CCCC([O-])=O JHPNVNIEXXLNTR-UHFFFAOYSA-N 0.000 title 1
- JHPNVNIEXXLNTR-UHFFFAOYSA-O 4-(trimethylammonio)butanoic acid Chemical compound C[N+](C)(C)CCCC(O)=O JHPNVNIEXXLNTR-UHFFFAOYSA-O 0.000 abstract 1
- XBDQKXXYIPTUBI-UHFFFAOYSA-M Propionate Chemical compound CCC([O-])=O XBDQKXXYIPTUBI-UHFFFAOYSA-M 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 231100000053 low toxicity Toxicity 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000007920 subcutaneous administration Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| LVP-95-256A LV11728B (en) | 1995-08-21 | 1995-08-21 | Pharmaceutical composition |
| PCT/LV1996/000002 WO1997006794A1 (en) | 1995-08-21 | 1996-08-20 | Pharmaceutical composition for treating cardiovascular diseases containing 3-(2,2,2-trimethylhydrazinium) propionate and gamma-butyrobetaine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE235901T1 true ATE235901T1 (de) | 2003-04-15 |
Family
ID=19736013
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96927931T ATE235901T1 (de) | 1995-08-21 | 1996-08-20 | Pharmazeutische zusammensetzung enthaltend 3-(2,2,2-trimethylhydrazinium)proprionat und gamma- butyrobetain für die behandlung von herz-gefäss- erkrankungen |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5859056A (de) |
| EP (1) | EP0845986B1 (de) |
| JP (1) | JP3072858B2 (de) |
| AT (1) | ATE235901T1 (de) |
| CA (1) | CA2229228C (de) |
| DE (1) | DE69627160T2 (de) |
| EA (1) | EA000472B1 (de) |
| ES (1) | ES2196167T3 (de) |
| LV (1) | LV11728B (de) |
| UA (1) | UA44330C2 (de) |
| WO (1) | WO1997006794A1 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LV12491B (lv) * | 1998-10-29 | 2000-12-20 | Ivars KALVI�� | Farmaceitiska kompozīcija |
| FI114538B (fi) * | 2001-01-12 | 2004-11-15 | Finnfeeds Finland Ltd | Glysiinibetaiinin käyttö verenpainetta alentavan tuotteen valmistukseen |
| LV12979B (en) * | 2001-09-07 | 2003-05-20 | Ivars Kalvins | Pharmaceutical composition |
| LV12978B (en) * | 2001-09-07 | 2003-05-20 | Ivars Kalvins | Pharmaceutical composition |
| JP4390134B2 (ja) | 2003-11-05 | 2009-12-24 | 日本精工株式会社 | ステアリング装置 |
| LV13450B (en) * | 2004-08-24 | 2006-11-20 | Grindeks As | Novel medicinal use of meldonium and pharmaceutical compositions thereof |
| LV14274B (lv) * | 2009-06-25 | 2011-03-20 | Grindeks, A/S | Meldoniju saturošs kombinēts medicīniskais produkts |
| WO2010149654A1 (en) * | 2009-06-25 | 2010-12-29 | Grindeks, A Joint Stock Company | Pharmaceutical composition of gamma-butyrobetaine or a pharmaceutically acceptable salt and meldonium or a pharmaceutically acceptable salt |
| LV14345B (lv) | 2009-10-22 | 2011-07-20 | Grindeks, A/S | 4-[Etil(dimetil)amonija]butanoāts un tā izmantošana kardiovaskulāro slimību ārstēšanai |
| CN103547562A (zh) * | 2011-04-27 | 2014-01-29 | 格林代克斯联合股份公司 | 4-[(卤代烷基)(二甲基)铵基]丁酸盐及其在治疗心血管疾病中的用途 |
| US20140088125A1 (en) | 2011-04-27 | 2014-03-27 | Jsc Grindeks | Use of 3-carboxy-n-ethyl-n,n-dimethylpropan-1-aminium salts in the treatment of cardiovascular disease |
| LV14848B (lv) * | 2012-10-25 | 2015-06-20 | Latvijas Organiskās Sintēzes Institūts | Farmaceitiska kompozīcija trimetilamīna-N-oksīda līmeņa pazemināšanai |
| GB201315321D0 (en) | 2013-08-28 | 2013-10-09 | Koninklijke Nederlandse Akademie Van Wetenschappen | Transduction Buffer |
| GB201521101D0 (en) | 2015-11-30 | 2016-01-13 | Koninklijke Nederlandse Akademie Van Wetenschappen | Transduction buffer |
| CN112180013B (zh) * | 2020-09-29 | 2022-11-15 | 上海脉示生物技术有限公司 | 用于心肌梗死诊断的肠道微生物代谢标志物组合物及其检测方法和应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1198434B (it) * | 1981-01-06 | 1988-12-21 | Sigma Tau Ind Farmaceuti | Composizione farmaceutica comprendente gamma butirrobetaina per il trattamento di sindromi da carenze di carnitina |
| IT1210935B (it) * | 1981-09-17 | 1989-09-29 | Inst Orch Sinteza Akademi Nauk | Composizione farmaceutica per il trattamento di malattie cardiovascolari. |
-
1995
- 1995-08-21 LV LVP-95-256A patent/LV11728B/lv unknown
-
1996
- 1996-08-20 JP JP09509171A patent/JP3072858B2/ja not_active Expired - Fee Related
- 1996-08-20 WO PCT/LV1996/000002 patent/WO1997006794A1/en not_active Ceased
- 1996-08-20 EA EA199800160A patent/EA000472B1/ru not_active IP Right Cessation
- 1996-08-20 DE DE69627160T patent/DE69627160T2/de not_active Expired - Lifetime
- 1996-08-20 US US09/011,380 patent/US5859056A/en not_active Expired - Lifetime
- 1996-08-20 EP EP96927931A patent/EP0845986B1/de not_active Expired - Lifetime
- 1996-08-20 CA CA002229228A patent/CA2229228C/en not_active Expired - Fee Related
- 1996-08-20 ES ES96927931T patent/ES2196167T3/es not_active Expired - Lifetime
- 1996-08-20 UA UA98020919A patent/UA44330C2/uk unknown
- 1996-08-20 AT AT96927931T patent/ATE235901T1/de active
Also Published As
| Publication number | Publication date |
|---|---|
| LV11728B (en) | 1997-08-20 |
| EP0845986A1 (de) | 1998-06-10 |
| CA2229228A1 (en) | 1997-02-27 |
| LV11728A (lv) | 1997-04-20 |
| CA2229228C (en) | 2008-07-08 |
| DE69627160D1 (de) | 2003-05-08 |
| UA44330C2 (uk) | 2002-02-15 |
| EP0845986B1 (de) | 2003-04-02 |
| US5859056A (en) | 1999-01-12 |
| WO1997006794A1 (en) | 1997-02-27 |
| DE69627160T2 (de) | 2004-02-12 |
| JP3072858B2 (ja) | 2000-08-07 |
| EA199800160A1 (ru) | 1998-08-27 |
| JPH10512286A (ja) | 1998-11-24 |
| ES2196167T3 (es) | 2003-12-16 |
| EA000472B1 (ru) | 1999-08-26 |
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