ATE235510T1 - Integrinbindendes peptid und dessen verwendung - Google Patents
Integrinbindendes peptid und dessen verwendungInfo
- Publication number
- ATE235510T1 ATE235510T1 AT98933671T AT98933671T ATE235510T1 AT E235510 T1 ATE235510 T1 AT E235510T1 AT 98933671 T AT98933671 T AT 98933671T AT 98933671 T AT98933671 T AT 98933671T AT E235510 T1 ATE235510 T1 AT E235510T1
- Authority
- AT
- Austria
- Prior art keywords
- binding peptide
- integrin binding
- lysine
- peptides
- integrin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/893,526 US6096707A (en) | 1997-07-11 | 1997-07-11 | Integrin binding peptide and use thereof |
PCT/FI1998/000579 WO1999002551A1 (en) | 1997-07-11 | 1998-07-09 | Integrin binding peptide and use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE235510T1 true ATE235510T1 (de) | 2003-04-15 |
Family
ID=25401719
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT98933671T ATE235510T1 (de) | 1997-07-11 | 1998-07-09 | Integrinbindendes peptid und dessen verwendung |
Country Status (17)
Country | Link |
---|---|
US (1) | US6096707A (de) |
EP (1) | EP0994898B1 (de) |
JP (1) | JP2001509515A (de) |
KR (1) | KR100571046B1 (de) |
CN (1) | CN1262688A (de) |
AT (1) | ATE235510T1 (de) |
AU (1) | AU748134B2 (de) |
BR (1) | BR9810586A (de) |
CA (1) | CA2295219C (de) |
DE (1) | DE69812630T2 (de) |
ES (1) | ES2195361T3 (de) |
HU (1) | HU225326B1 (de) |
NO (1) | NO20000126D0 (de) |
NZ (1) | NZ501767A (de) |
PL (1) | PL338001A1 (de) |
RU (1) | RU2203902C2 (de) |
WO (1) | WO1999002551A1 (de) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7914814B2 (en) * | 1997-09-17 | 2011-03-29 | Strategic Science & Technologies, Llc | Topical delivery of arginine of cause beneficial effects |
US7387779B2 (en) | 1998-06-17 | 2008-06-17 | Beth Israel Deaconess Medical Center | Anti-angiogenic proteins and fragments and methods of use thereof |
US6759047B1 (en) | 1998-06-17 | 2004-07-06 | Beth Israel Deaconess Hospital Corp. | Anti-angiogenic proteins and methods of use thereof |
US6962974B1 (en) | 1998-06-17 | 2005-11-08 | Beth Israel Deaconess Medical Center | Anti-angiogenic proteins and fragments and methods of use thereof |
GB9817623D0 (en) * | 1998-08-13 | 1998-10-07 | Glaxo Group Ltd | Pharmaceutical compounds |
CN101025419A (zh) * | 2001-02-21 | 2007-08-29 | 卫材R&D管理有限公司 | 测定通过抑制整联蛋白表达所介导的血管生成抑制剂的作用的方法 |
CN1507354A (zh) * | 2001-03-02 | 2004-06-23 | ͨ��ҽ�ƹ�˾ | 通过给予整合蛋白αvβ3拮抗剂并与其它预防或治疗药剂配合来预防或者治疗炎性疾病或自身免疫疾病的方法 |
JP2005525368A (ja) * | 2002-03-04 | 2005-08-25 | メディミューン,インコーポレーテッド | インテグリンαvβ3アンタゴニストをHMG−CoA還元酵素阻害剤またはビスフォスフォネートと併用投与する障害の予防または治療方法 |
WO2003075957A1 (en) * | 2002-03-04 | 2003-09-18 | Medimmune, Inc. | The prevention or treatment of cancer using integrin alphavbeta3 antagonists in combination with other agents |
EP1499352A4 (de) * | 2002-04-12 | 2006-10-11 | Medimmune Inc | Rekombinante anti-interleukin-9-antikörper |
WO2003092632A2 (en) * | 2002-05-06 | 2003-11-13 | The Scripps Research Institute | Cyclic peptide anti-cancer agents and methods |
CA2514653A1 (en) * | 2003-01-30 | 2004-08-12 | Medimmune, Inc. | Uses of integrin alphavbeta3 antagonists |
AU2004229501B2 (en) | 2003-04-11 | 2011-08-18 | Medimmune, Llc | Recombinant IL-9 antibodies and uses thereof |
US7196061B2 (en) * | 2003-09-10 | 2007-03-27 | Wyeth | Compounds that modulate neuronal growth and their uses |
US7351739B2 (en) * | 2004-04-30 | 2008-04-01 | Wellgen, Inc. | Bioactive compounds and methods of uses thereof |
EP2422811A2 (de) | 2004-10-27 | 2012-02-29 | MedImmune, LLC | Modulation von Antikörperspezifität mittels Anpassung der Affinität zu verwandten Antigenen |
JP2008542445A (ja) * | 2005-06-07 | 2008-11-27 | ザ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・ペンシルバニア | α2β1/GPIa−IIaインテグリン阻害剤 |
US8987306B2 (en) * | 2005-06-07 | 2015-03-24 | The Trustees Of The University Of Pennsylvania | Inhibitors of integrin alpha2beta1 based on prolyl diaminopropionic acid scaffold |
WO2007020405A2 (en) * | 2005-08-12 | 2007-02-22 | Cartela R & D Ab | Integrin i-domain binding peptides |
JP4826721B2 (ja) * | 2005-08-18 | 2011-11-30 | 三菱電機株式会社 | マンコンベアの制御装置 |
WO2007027742A2 (en) * | 2005-08-31 | 2007-03-08 | The Trustees Of The University Of Pennsylvania | SMALL MOLECULE INTEGRIN α2βl/GPIa-IIa ANTAGONISTS |
JP2009510105A (ja) | 2005-09-28 | 2009-03-12 | バイオバスキュラー インコーポレーティッド | 血小板および細胞の接着、細胞移動、および炎症を阻止するための方法および組成物 |
US8324154B2 (en) * | 2005-12-22 | 2012-12-04 | Novabiotics, Ltd. | Treatment of fungal infections with cyclic antimicrobial peptides |
AU2007272970C1 (en) | 2006-07-11 | 2013-01-10 | Roy C. Levitt | Rhinosinusitis prevention and therapy with proinflammatory cytokine inhibitors |
CA3177366A1 (en) | 2006-08-10 | 2008-02-21 | Roy C. Levitt | Localized therapy of lower airways inflammatory disorders with proinflammatory cytokine inhibitors |
GB0618512D0 (en) * | 2006-09-20 | 2006-11-01 | Lexcicon Ltd | Peptides |
FI20075258A0 (fi) * | 2007-04-17 | 2007-04-17 | Biotie Therapies Corp | Menetelmä integriiniinhibiittorirespondereiden seulomiseksi |
US20110256058A1 (en) * | 2007-10-17 | 2011-10-20 | University Of Southern California | Novel Peptides and Uses Thereof |
US8563690B2 (en) * | 2008-11-03 | 2013-10-22 | The Board Of Trustees Of The University Of Illinois | Modulation of platelet aggregation |
CA2793838C (en) | 2010-03-19 | 2019-09-17 | H. Lee Moffitt Cancer Center & Research Institute, Inc. | Integrin interaction inhibitors for the treatment of cancer |
WO2012113803A1 (en) | 2011-02-22 | 2012-08-30 | Leo Pharma A/S | A cyclic peptide and conjugate thereof for binding to keratinocytes |
US10011635B2 (en) | 2013-09-27 | 2018-07-03 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Cyclic peptide conjugates and methods of use |
JP6866296B2 (ja) * | 2015-02-27 | 2021-04-28 | ボード オブ リージェンツ, ザ ユニバーシティ オブ テキサス システムBoard Of Regents, The University Of Texas System | ポリペプチド治療及びその使用 |
JP7496826B2 (ja) | 2018-09-10 | 2024-06-07 | ラング セラピューティクス,エルエルシー | Cav-1タンパク質の修飾ペプチドフラグメント及び線維症の治療におけるその使用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5179007A (en) * | 1989-07-07 | 1993-01-12 | The Texas A & M University System | Method and vector for the purification of foreign proteins |
WO1994014836A1 (en) * | 1992-12-18 | 1994-07-07 | Centocor, Inc. | Peptide inhibitors of selectin binding |
US5627263A (en) * | 1993-11-24 | 1997-05-06 | La Jolla Cancer Research Foundation | Integrin-binding peptides |
EP0767674A4 (de) * | 1994-06-29 | 1999-06-16 | Texas Biotechnology Corp | Verfahren zur hemmung der bindung von integrin alpha 4 beta 1 an vcam-1 oder fibronectin |
-
1997
- 1997-07-11 US US08/893,526 patent/US6096707A/en not_active Expired - Fee Related
-
1998
- 1998-07-09 AT AT98933671T patent/ATE235510T1/de not_active IP Right Cessation
- 1998-07-09 JP JP2000502070A patent/JP2001509515A/ja active Pending
- 1998-07-09 RU RU2000103210/04A patent/RU2203902C2/ru not_active IP Right Cessation
- 1998-07-09 BR BR9810586-8A patent/BR9810586A/pt not_active Application Discontinuation
- 1998-07-09 DE DE69812630T patent/DE69812630T2/de not_active Expired - Fee Related
- 1998-07-09 HU HU0002789A patent/HU225326B1/hu not_active IP Right Cessation
- 1998-07-09 EP EP98933671A patent/EP0994898B1/de not_active Expired - Lifetime
- 1998-07-09 CA CA002295219A patent/CA2295219C/en not_active Expired - Fee Related
- 1998-07-09 NZ NZ501767A patent/NZ501767A/xx unknown
- 1998-07-09 AU AU83413/98A patent/AU748134B2/en not_active Ceased
- 1998-07-09 ES ES98933671T patent/ES2195361T3/es not_active Expired - Lifetime
- 1998-07-09 WO PCT/FI1998/000579 patent/WO1999002551A1/en active IP Right Grant
- 1998-07-09 PL PL98338001A patent/PL338001A1/xx not_active Application Discontinuation
- 1998-07-09 KR KR1020007000051A patent/KR100571046B1/ko not_active IP Right Cessation
- 1998-07-09 CN CN98806979A patent/CN1262688A/zh active Pending
-
2000
- 2000-01-10 NO NO20000126A patent/NO20000126D0/no unknown
Also Published As
Publication number | Publication date |
---|---|
JP2001509515A (ja) | 2001-07-24 |
AU748134B2 (en) | 2002-05-30 |
CN1262688A (zh) | 2000-08-09 |
KR100571046B1 (ko) | 2006-04-13 |
AU8341398A (en) | 1999-02-08 |
BR9810586A (pt) | 2000-09-05 |
HU225326B1 (en) | 2006-09-28 |
CA2295219C (en) | 2007-01-02 |
KR20010015547A (ko) | 2001-02-26 |
NO20000126L (no) | 2000-01-10 |
EP0994898B1 (de) | 2003-03-26 |
CA2295219A1 (en) | 1999-01-21 |
HUP0002789A3 (en) | 2003-08-28 |
NO20000126D0 (no) | 2000-01-10 |
DE69812630T2 (de) | 2004-02-05 |
DE69812630D1 (de) | 2003-04-30 |
HUP0002789A2 (hu) | 2000-12-28 |
US6096707A (en) | 2000-08-01 |
PL338001A1 (en) | 2000-09-25 |
WO1999002551A1 (en) | 1999-01-21 |
NZ501767A (en) | 2002-08-28 |
ES2195361T3 (es) | 2003-12-01 |
EP0994898A1 (de) | 2000-04-26 |
RU2203902C2 (ru) | 2003-05-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 0994898 Country of ref document: EP |
|
REN | Ceased due to non-payment of the annual fee |