ATE234934T1 - Verfahren zur herstellung von einem beta-laktam antibiotikum - Google Patents
Verfahren zur herstellung von einem beta-laktam antibiotikumInfo
- Publication number
- ATE234934T1 ATE234934T1 AT98949243T AT98949243T ATE234934T1 AT E234934 T1 ATE234934 T1 AT E234934T1 AT 98949243 T AT98949243 T AT 98949243T AT 98949243 T AT98949243 T AT 98949243T AT E234934 T1 ATE234934 T1 AT E234934T1
- Authority
- AT
- Austria
- Prior art keywords
- beta
- acylation
- reaction
- lactam nucleus
- lactam
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P37/00—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin
- C12P37/04—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin by acylation of the substituent in the 6 position
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
- C12P35/04—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin by acylation of the substituent in the 7 position
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL1007302A NL1007302C2 (nl) | 1997-10-17 | 1997-10-17 | Werkwijze voor de bereiding van een ß-lactam antibioticum. |
| PCT/NL1998/000570 WO1999020786A1 (en) | 1997-10-17 | 1998-10-01 | PROCESS FOR THE PREPARATION OF A β-LACTAM ANTIBIOTIC |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE234934T1 true ATE234934T1 (de) | 2003-04-15 |
Family
ID=19765855
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98949243T ATE234934T1 (de) | 1997-10-17 | 1998-10-01 | Verfahren zur herstellung von einem beta-laktam antibiotikum |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6287799B1 (de) |
| EP (1) | EP1023454B1 (de) |
| KR (1) | KR100516271B1 (de) |
| CN (1) | CN1165626C (de) |
| AT (1) | ATE234934T1 (de) |
| AU (1) | AU9560198A (de) |
| BR (1) | BR9813079A (de) |
| EG (1) | EG21235A (de) |
| ES (1) | ES2195400T3 (de) |
| IN (1) | IN188152B (de) |
| NL (1) | NL1007302C2 (de) |
| TR (1) | TR200000991T2 (de) |
| WO (1) | WO1999020786A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL1006266C2 (nl) | 1997-06-10 | 1998-12-14 | Chemferm Vof | Werkwijze voor de bereiding van ampicilline. |
| EP1394262A1 (de) * | 2002-08-30 | 2004-03-03 | Bioferma Murcia, S.A. | Enzymatischer Prozess zur Herstellung von beta-Lactamverbindungen |
| BRPI0519476B8 (pt) * | 2004-12-27 | 2021-05-25 | Dsm Ip Assets Bv | processo para a síntese de cefaclor e processo para obtenção de cefaclor |
| MX2008014711A (es) | 2006-05-19 | 2008-12-03 | Dsm Ip Assets Bv | Procedimiento para la cristalizacion de cefadroxilo. |
| CN101525603B (zh) * | 2008-03-04 | 2013-12-25 | 中国医药集团总公司四川抗菌素工业研究所 | 固定化α-氨基酸酯水解酶及其制备与应用 |
| WO2012175587A2 (en) | 2011-06-23 | 2012-12-27 | Dsm Sinochem Pharmaceuticals Netherlands B.V. | Novel crystalline cefoperazone intermediate |
| PL2723882T3 (pl) | 2011-06-23 | 2020-01-31 | Centrient Pharmaceuticals Netherlands B.V. | Sposób wytwarzania 3’-tiopodstawionych cefalosporyn z zastosowaniem acylazy penicyliny |
| CN103467493B (zh) * | 2013-10-16 | 2016-01-20 | 华北制药集团先泰药业有限公司 | 无水氨苄西林的制备方法 |
| CN103757085B (zh) * | 2013-11-28 | 2016-06-15 | 湖南福来格生物技术有限公司 | 头孢克洛及其合成方法 |
| CN103937692B (zh) * | 2014-04-30 | 2016-03-23 | 江南大学 | 一株丝枝霉菌株及其生产β-葡萄糖苷酶的方法 |
| US20170101660A1 (en) | 2015-10-07 | 2017-04-13 | Gwangju Institute Of Science And Technology | Enzyme-immobilized porous membrane and preparation method of antibiotics using the same |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ381392A3 (en) * | 1990-07-04 | 1993-12-15 | Novo Nordisk As | Process for preparing beta-lactams |
| EP0771357B1 (de) * | 1994-07-18 | 1999-10-20 | Dsm N.V. | Verfahren zur herstellung von beta-lactamen mit dauernd hochkonzentrierten reagenzien |
| BE1009071A3 (nl) * | 1995-02-02 | 1996-11-05 | Dsm Nv | Werkwijze voor de bereiding van een beta-lactam antibioticum. |
| US5770272A (en) * | 1995-04-28 | 1998-06-23 | Massachusetts Institute Of Technology | Matrix-bearing targets for maldi mass spectrometry and methods of production thereof |
| EP0865443B1 (de) * | 1995-12-08 | 2003-03-19 | Dsm N.V. | Verfahren zur herstellung eines anitibiotkums |
-
1997
- 1997-10-17 NL NL1007302A patent/NL1007302C2/nl not_active IP Right Cessation
-
1998
- 1998-10-01 KR KR10-2000-7004098A patent/KR100516271B1/ko not_active IP Right Cessation
- 1998-10-01 TR TR2000/00991T patent/TR200000991T2/xx unknown
- 1998-10-01 US US09/529,569 patent/US6287799B1/en not_active Expired - Fee Related
- 1998-10-01 CN CNB988122804A patent/CN1165626C/zh not_active Expired - Lifetime
- 1998-10-01 EP EP98949243A patent/EP1023454B1/de not_active Expired - Lifetime
- 1998-10-01 BR BR9813079-0A patent/BR9813079A/pt not_active IP Right Cessation
- 1998-10-01 AT AT98949243T patent/ATE234934T1/de active
- 1998-10-01 ES ES98949243T patent/ES2195400T3/es not_active Expired - Lifetime
- 1998-10-01 AU AU95601/98A patent/AU9560198A/en not_active Abandoned
- 1998-10-01 WO PCT/NL1998/000570 patent/WO1999020786A1/en active IP Right Grant
- 1998-10-07 IN IN2240MA1998 patent/IN188152B/en unknown
- 1998-10-17 EG EG125898A patent/EG21235A/xx active
Also Published As
| Publication number | Publication date |
|---|---|
| TR200000991T2 (tr) | 2000-07-21 |
| CN1282377A (zh) | 2001-01-31 |
| ES2195400T3 (es) | 2003-12-01 |
| NL1007302C2 (nl) | 1999-04-20 |
| EG21235A (en) | 2001-03-31 |
| KR100516271B1 (ko) | 2005-09-20 |
| EP1023454B1 (de) | 2003-03-19 |
| EP1023454A1 (de) | 2000-08-02 |
| KR20010024519A (ko) | 2001-03-26 |
| US6287799B1 (en) | 2001-09-11 |
| IN188152B (de) | 2002-08-24 |
| WO1999020786A1 (en) | 1999-04-29 |
| AU9560198A (en) | 1999-05-10 |
| CN1165626C (zh) | 2004-09-08 |
| BR9813079A (pt) | 2000-08-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1023454 Country of ref document: EP |
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