ATE233279T1 - Spezifisch bindende agentien - Google Patents
Spezifisch bindende agentienInfo
- Publication number
- ATE233279T1 ATE233279T1 AT91308147T AT91308147T ATE233279T1 AT E233279 T1 ATE233279 T1 AT E233279T1 AT 91308147 T AT91308147 T AT 91308147T AT 91308147 T AT91308147 T AT 91308147T AT E233279 T1 ATE233279 T1 AT E233279T1
- Authority
- AT
- Austria
- Prior art keywords
- human antibody
- reshaped
- specific binding
- binding agents
- hmfg1
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
- C07K16/461—Igs containing Ig-regions, -domains or -residues form different species
- C07K16/464—Igs containing CDR-residues from one specie grafted between FR-residues from another
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pretreatment Of Seeds And Plants (AREA)
- Nonmetallic Welding Materials (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB909019553A GB9019553D0 (en) | 1990-09-07 | 1990-09-07 | Specific binding agents |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE233279T1 true ATE233279T1 (de) | 2003-03-15 |
Family
ID=10681827
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT91308147T ATE233279T1 (de) | 1990-09-07 | 1991-09-05 | Spezifisch bindende agentien |
Country Status (18)
Country | Link |
---|---|
US (2) | US6204366B1 (de) |
EP (1) | EP0483961B1 (de) |
JP (2) | JP3514456B2 (de) |
KR (1) | KR930702526A (de) |
AT (1) | ATE233279T1 (de) |
AU (1) | AU653167B2 (de) |
BG (1) | BG60716B1 (de) |
CA (1) | CA2090961C (de) |
DE (1) | DE69133200T2 (de) |
DK (1) | DK0483961T3 (de) |
ES (1) | ES2193129T3 (de) |
FI (2) | FI113873B (de) |
GB (1) | GB9019553D0 (de) |
HU (2) | HUT67796A (de) |
NO (2) | NO314595B1 (de) |
RO (1) | RO113432B1 (de) |
UA (1) | UA46691C2 (de) |
WO (1) | WO1992004380A1 (de) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK0590058T3 (da) | 1991-06-14 | 2004-03-29 | Genentech Inc | Humaniseret heregulin-antistof |
WO1994004679A1 (en) * | 1991-06-14 | 1994-03-03 | Genentech, Inc. | Method for making humanized antibodies |
US6800738B1 (en) | 1991-06-14 | 2004-10-05 | Genentech, Inc. | Method for making humanized antibodies |
US5869619A (en) * | 1991-12-13 | 1999-02-09 | Xoma Corporation | Modified antibody variable domains |
EP0571613B1 (de) * | 1991-12-13 | 2003-09-17 | Xoma Corporation | Verfahren und materialien zur herstellung von modifizierten variablen antikörperdomänen und ihre therapeutische verwendung |
AU5615594A (en) * | 1992-11-13 | 1994-06-08 | Cancer Research Fund Of Contra Costa | Polypeptides with specificity for neoplasias, kit, and diagnostic, vaccination, and therapeutic methods |
US6281335B1 (en) * | 1993-10-08 | 2001-08-28 | Coulter Corporation | Hybridoma and anti-KC-4 humanized monoclonal antibody |
US5804187A (en) | 1992-11-16 | 1998-09-08 | Cancer Research Fund Of Contra Costa | Modified antibodies with human milk fat globule specificity |
AU6396494A (en) * | 1992-11-16 | 1994-06-08 | Cancer Research Fund Of Contra Costa | Peptides and anti-sense peptides with broad neoplastic specificity |
US5792852A (en) * | 1992-11-16 | 1998-08-11 | Cancer Research Fund Of Contra Costa | Polynucleotides encoding modified antibodies with human milk fat globule specificity |
JPH07203974A (ja) * | 1994-01-13 | 1995-08-08 | Tosoh Corp | 癌特異的ムチンを認識する抗体の遺伝子断片等 |
EP0781847A1 (de) * | 1995-11-06 | 1997-07-02 | MERCK PATENT GmbH | Humanisierter monoklonaler Antikörper |
BR9815289A (pt) * | 1997-11-14 | 2001-12-26 | Euro Celtique Sa | Imunoglobulina modificada, molécula, ácidonucleico isolado, célula contendo o mesmo, animalnão-humano recombinante, composiçãofarmacêutica, composição de vacina, processospara identificar ou medir ou detectar um antìgenode câncer, um antìgeno de um agente de doençainfecciosa, um ligante, e um receptor em umaamostra a ser testada, kits para detecção de umantìgeno de câncer, de um antìgeno de um agentede doença infecciosa, de um receptor celular paraum agente de doença infecciosa, de um ligante, e deum antìgeno de câncer, processos de diagnósticoou de exame para a presença de ou umapredisposição para desenvolvimento de um câncertipificado pela presença aumentada de umantìgeno de câncer, e para a presença de umagente de doença infecciosa, processos detratamento ou de prevenção de um câncertipificado pela presença de um antìgeno de câncer,de uma doença infecciosa tipificada pela presençade um antìgeno de agente de doença infecciosa, ede uma doença causada por um agente de doençainfecciosa que se liga em um receptor celular,processos para modulação de atividade de umprimeiro membro de um par de ligação, processo deprodução de uma imunoglobulina modificada,processo de produção de um ácido nucleicocodificador de imunoglobulina modificada, e, ácidonucleico isolado |
GB2360771A (en) * | 2000-03-28 | 2001-10-03 | Antisoma Res Ltd | Compounds for targeting |
AU4430701A (en) * | 2000-04-03 | 2001-10-15 | Antisoma Research Limited | Compounds for targeting |
AU2002307064A1 (en) * | 2001-04-02 | 2002-10-15 | Purdue Pharma L.P. | Immunoglobulin construct containing anti-mucin variable domain sequences for eliciting an anti-idiotype anti-tumor response |
GB0200657D0 (en) * | 2002-01-12 | 2002-02-27 | Antisoma Plc | Cancer treatment |
WO2003102157A2 (en) * | 2002-06-03 | 2003-12-11 | Genentech, Inc. | Synthetic antibody phage libraries |
AU2003256566A1 (en) * | 2002-07-16 | 2004-02-02 | Stuart Bussell | Methods to construct multimeric dna and polymeric protein sequences as direct fusions or with linkers |
CA2534055A1 (en) * | 2003-08-01 | 2005-02-10 | Genentech, Inc. | Antibody cdr polypeptide sequences with restricted diversity |
GB0519398D0 (en) * | 2005-09-23 | 2005-11-02 | Antisoma Plc | Biological materials and uses thereof |
WO2007056441A2 (en) | 2005-11-07 | 2007-05-18 | Genentech, Inc. | Binding polypeptides with diversified and consensus vh/vl hypervariable sequences |
US20070237764A1 (en) * | 2005-12-02 | 2007-10-11 | Genentech, Inc. | Binding polypeptides with restricted diversity sequences |
KR101920250B1 (ko) * | 2010-10-13 | 2018-11-20 | 얀센 바이오테크 인코포레이티드 | 인간 온코스타틴 m 항체 및 이용 방법 |
JP2014510080A (ja) * | 2011-03-09 | 2014-04-24 | セントローズ, エルエルシー | 細胞外標的化薬物複合体 |
RU2493165C1 (ru) * | 2012-02-28 | 2013-09-20 | Общество с ограниченной ответственностью "Технофарма" | Наноантитело, специфически связывающее белок muc1, способ детекции белка muc1 с помощью наноантител |
CA2872010C (en) | 2012-04-30 | 2021-06-08 | Biothera, Inc. | Compositions and methods for .beta.-glucan immunotherapy |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8607679D0 (en) * | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
WO1988005054A1 (en) * | 1987-01-07 | 1988-07-14 | Imperial Cancer Research Technology Limited | Probe |
DE3853515T3 (de) * | 1987-05-21 | 2005-08-25 | Micromet Ag | Multifunktionelle proteine mit vorbestimmter zielsetzung. |
JPH03503120A (ja) * | 1988-02-08 | 1991-07-18 | ジョン ミュア キャンサー アンド エージング インスティチュート ディビジョン オブ ジョン ミュア メモリアル ホスピタル | ヒトのガン細胞における新規なムチン様糖蛋白質表面抗原に特異的なモノクローナル抗体 |
EP0442926A1 (de) * | 1988-11-10 | 1991-08-28 | Imperial Cancer Research Technology Limited | Polypeptide |
JPH02273195A (ja) * | 1988-11-17 | 1990-11-07 | Univ Melbourne | ヒト多型性上皮ムチンと反応するモノクローナル抗体 |
US5075219A (en) * | 1989-04-05 | 1991-12-24 | John Muir Cancer & Aging Institute | Monoclonal antibody which recognizes a specific glycoprotein of a human milk-fat globule membrane mucin antigen and said mucin antigen |
KR970007783B1 (ko) * | 1989-11-17 | 1997-05-16 | 유니레버 엔 브이 | 특이적 결합제 |
-
1990
- 1990-09-07 GB GB909019553A patent/GB9019553D0/en active Pending
-
1991
- 1991-09-05 JP JP51496191A patent/JP3514456B2/ja not_active Expired - Lifetime
- 1991-09-05 ES ES91308147T patent/ES2193129T3/es not_active Expired - Lifetime
- 1991-09-05 UA UA93080844A patent/UA46691C2/uk unknown
- 1991-09-05 WO PCT/GB1991/001511 patent/WO1992004380A1/en active IP Right Grant
- 1991-09-05 US US07/987,264 patent/US6204366B1/en not_active Expired - Lifetime
- 1991-09-05 HU HU9300609A patent/HUT67796A/hu unknown
- 1991-09-05 AT AT91308147T patent/ATE233279T1/de not_active IP Right Cessation
- 1991-09-05 EP EP91308147A patent/EP0483961B1/de not_active Expired - Lifetime
- 1991-09-05 HU HU9300609A patent/HU9300609D0/hu unknown
- 1991-09-05 AU AU84953/91A patent/AU653167B2/en not_active Expired
- 1991-09-05 RO RO93-00310A patent/RO113432B1/ro unknown
- 1991-09-05 KR KR1019930700678A patent/KR930702526A/ko not_active Application Discontinuation
- 1991-09-05 CA CA002090961A patent/CA2090961C/en not_active Expired - Lifetime
- 1991-09-05 DK DK91308147T patent/DK0483961T3/da active
- 1991-09-05 DE DE69133200T patent/DE69133200T2/de not_active Expired - Lifetime
-
1993
- 1993-03-05 NO NO19930825A patent/NO314595B1/no not_active IP Right Cessation
- 1993-03-05 FI FI930984A patent/FI113873B/fi not_active IP Right Cessation
- 1993-04-05 BG BG97607A patent/BG60716B1/bg unknown
-
2000
- 2000-12-28 US US09/749,831 patent/US20020086978A1/en not_active Abandoned
-
2001
- 2001-08-31 FI FI20011739A patent/FI114611B/fi not_active IP Right Cessation
- 2001-10-04 NO NO20014822A patent/NO315239B1/no not_active IP Right Cessation
-
2002
- 2002-05-30 JP JP2002157535A patent/JP2003061689A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
AU8495391A (en) | 1992-03-30 |
NO930825D0 (no) | 1993-03-05 |
FI930984A0 (fi) | 1993-03-05 |
NO315239B1 (no) | 2003-08-04 |
JP2003061689A (ja) | 2003-03-04 |
US6204366B1 (en) | 2001-03-20 |
EP0483961B1 (de) | 2003-02-26 |
FI113873B (fi) | 2004-06-30 |
WO1992004380A1 (en) | 1992-03-19 |
NO20014822D0 (no) | 2001-10-04 |
HU9300609D0 (en) | 1993-05-28 |
DE69133200T2 (de) | 2003-11-20 |
UA46691C2 (uk) | 2002-06-17 |
HUT67796A (en) | 1995-04-28 |
ES2193129T3 (es) | 2003-11-01 |
DE69133200D1 (de) | 2003-04-03 |
AU653167B2 (en) | 1994-09-22 |
NO314595B1 (no) | 2003-04-14 |
KR930702526A (ko) | 1993-09-09 |
NO20014822L (no) | 1993-05-05 |
CA2090961C (en) | 2004-01-20 |
JPH06500468A (ja) | 1994-01-20 |
BG60716B1 (en) | 1996-01-31 |
NO930825L (no) | 1993-05-05 |
EP0483961A1 (de) | 1992-05-06 |
GB9019553D0 (en) | 1990-10-24 |
FI114611B (fi) | 2004-11-30 |
JP3514456B2 (ja) | 2004-03-31 |
RO113432B1 (ro) | 1998-07-30 |
DK0483961T3 (da) | 2003-06-23 |
CA2090961A1 (en) | 1992-03-08 |
BG97607A (bg) | 1994-03-31 |
US20020086978A1 (en) | 2002-07-04 |
FI930984A (fi) | 1993-03-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 0483961 Country of ref document: EP |
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EELA | Cancelled due to lapse of time |