ATE225340T1 - Einschlusskomplexe von taxol oder taxotere oder taxus-extrakten und cyclodextrinen, ihre herstellung und ihre verwendung - Google Patents
Einschlusskomplexe von taxol oder taxotere oder taxus-extrakten und cyclodextrinen, ihre herstellung und ihre verwendungInfo
- Publication number
- ATE225340T1 ATE225340T1 AT94918994T AT94918994T ATE225340T1 AT E225340 T1 ATE225340 T1 AT E225340T1 AT 94918994 T AT94918994 T AT 94918994T AT 94918994 T AT94918994 T AT 94918994T AT E225340 T1 ATE225340 T1 AT E225340T1
- Authority
- AT
- Austria
- Prior art keywords
- taxotere
- taxol
- preparation
- cyclodextrins
- inclusion complexes
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nanotechnology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Biotechnology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Biophysics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicines Containing Plant Substances (AREA)
- Epoxy Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU9301373A HU213200B (en) | 1993-05-12 | 1993-05-12 | The cyclodextrin or cyclodextrin derivative cluster complexes of taxol, taxotere, or taxus, pharmaceutical preparations containing them and process for their production |
| PCT/HU1994/000012 WO1994026728A1 (en) | 1993-05-12 | 1994-05-09 | Inclusion complexes of taxol or taxotere or taxus extract formed with cyclodextrins, its preparation and use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE225340T1 true ATE225340T1 (de) | 2002-10-15 |
Family
ID=10983581
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94918994T ATE225340T1 (de) | 1993-05-12 | 1994-05-09 | Einschlusskomplexe von taxol oder taxotere oder taxus-extrakten und cyclodextrinen, ihre herstellung und ihre verwendung |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US6284746B1 (de) |
| EP (1) | EP0698018B1 (de) |
| JP (1) | JP3693341B2 (de) |
| CN (1) | CN1123030A (de) |
| AT (1) | ATE225340T1 (de) |
| AU (1) | AU693101B2 (de) |
| BG (1) | BG100207A (de) |
| BR (1) | BR9406292A (de) |
| CA (1) | CA2162716C (de) |
| CZ (1) | CZ291495A3 (de) |
| DE (1) | DE69431476T2 (de) |
| DK (1) | DK0698018T3 (de) |
| ES (1) | ES2184764T3 (de) |
| FI (1) | FI955424A (de) |
| HU (1) | HU213200B (de) |
| IL (1) | IL109613A (de) |
| NO (1) | NO954545L (de) |
| OA (1) | OA10323A (de) |
| PL (1) | PL311561A1 (de) |
| PT (1) | PT698018E (de) |
| SK (1) | SK140595A3 (de) |
| WO (1) | WO1994026728A1 (de) |
| YU (1) | YU26894A (de) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5716981A (en) * | 1993-07-19 | 1998-02-10 | Angiogenesis Technologies, Inc. | Anti-angiogenic compositions and methods of use |
| HUT73844A (en) * | 1994-11-11 | 1996-09-30 | Chinoin Gyogyszer Es Vegyeszet | New taxol complexes and pharmaceutical compositions containing them |
| HUP9701945A3 (en) * | 1997-11-10 | 2000-04-28 | Hexal Ag | Pharmaceutical composition for injection containing cyclodextrin and taxoids |
| NZ506389A (en) * | 1998-02-05 | 2003-07-25 | Novartis Ag | Pharmaceutical compositions containing epothilone which can be optionally lyophilised |
| US6683100B2 (en) | 1999-01-19 | 2004-01-27 | Novartis Ag | Organic compounds |
| US6194181B1 (en) * | 1998-02-19 | 2001-02-27 | Novartis Ag | Fermentative preparation process for and crystal forms of cytostatics |
| TWI321054B (en) * | 2000-12-19 | 2010-03-01 | California Inst Of Techn | Compositions containing inclusion complexes |
| GB0127677D0 (en) * | 2001-11-19 | 2002-01-09 | Vianex S A | Inclusion complex |
| US20040106199A1 (en) * | 2002-12-02 | 2004-06-03 | Eliseev Alexey V. | Charged cyclodextrin derivatives and their use in plant cell and tissue culture growth media |
| CN100486645C (zh) | 2006-09-12 | 2009-05-13 | 南京师范大学 | 含有环糊精紫杉醇包合物的药物组合物及其制备方法 |
| CN100411688C (zh) * | 2006-09-12 | 2008-08-20 | 南京师范大学 | 含有环糊精/多烯紫杉醇包合物的药物组合物及其制备方法 |
| CN101278929B (zh) * | 2007-04-02 | 2011-05-18 | 王效山 | 含有藤黄酸类化合物的药物及藤黄酸类化合物的包合物的制备方法 |
| ES2310122B1 (es) * | 2007-04-20 | 2009-10-30 | Instituto Cientifico Y Tecnologico De Navarra, S.A | Nanoparticulas que comprenden una ciclodextrina y una molecula biologicamente activa y sus aplicaciones. |
| ITMI20071321A1 (it) * | 2007-07-04 | 2009-01-05 | Sea Marconi Technologies Di Va | Nanospugne a base di ciclodestrine come veicolo per farmaci antitumorali |
| CL2007003876A1 (es) * | 2007-12-28 | 2008-03-07 | Univ De Concepcion Y Lab Andro | Complejo de inclusion que esta formado por disulfiram y ciclodextrina; procedimiento de preparacion; composicion farmaceutica; y uso en el tratamiento de la dependencia de alcohol y cocaina. |
| ES2464729T3 (es) | 2008-08-21 | 2014-06-03 | The Johns Hopkins University | Procedimientos y composiciones para la administración de 3-halopiruvato y compuestos relacionados para el tratamiento del cáncer |
| EP3094313A4 (de) * | 2014-01-14 | 2017-07-12 | The Johns Hopkins University | Liposomzusammensetzungen zur einkapselung modifizierter cyclodextrinkomplexe und verwendungen davon |
| CN103920163B (zh) * | 2014-03-14 | 2016-09-14 | 南京大学 | 一种紫杉醇复合物、制备方法及其应用 |
| US10751306B2 (en) | 2015-11-06 | 2020-08-25 | The Johns Hopkins University | Methods of treating liver fibrosis by administering 3-bromopyruvate |
| GB201715008D0 (en) * | 2017-09-18 | 2017-11-01 | Inst De Medicina Molecular Faculdade De Medicina Univ De Lisboa | TRPV2 Antagonists |
| JP7274785B2 (ja) | 2018-07-25 | 2023-05-17 | ビカ バイオテクノロジー （グアンジョウ） カンパニー リミテッド | 注射用ドセタキセル組成物およびそのための調製法 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU181703B (en) * | 1980-05-09 | 1983-11-28 | Chinoin Gyogyszer Es Vegyeszet | Process for producing aqueus solutuins of water insoluble or hardly soluble vitamines, steroides, localanesthetics, prostanoides and non-steroid and antiphlogistic agents |
| HU191101B (en) * | 1983-02-14 | 1987-01-28 | Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt,Hu | Process for preparing water-soluble cyclodextrin polymers substituted with ionic groups |
| JPS62120324A (ja) * | 1985-11-20 | 1987-06-01 | Nippon Junyaku Kk | 有機物質の水溶化方法 |
| JP2651567B2 (ja) * | 1986-03-20 | 1997-09-10 | 花王株式会社 | メチル化β−シクロデキストリン |
| IE62095B1 (en) * | 1988-03-29 | 1994-12-14 | Univ Florida | Pharmaceutical formulations for parenteral use |
| JP2929108B2 (ja) * | 1988-10-28 | 1999-08-03 | 株式会社資生堂 | 化粧料および粉末化粧料 |
| IT1227626B (it) | 1988-11-28 | 1991-04-23 | Vectorpharma Int | Farmaci supportati aventi velocita' di dissoluzione aumentata e procedimento per la loro preparazione |
| JPH02200671A (ja) * | 1989-01-30 | 1990-08-08 | Agency Of Ind Science & Technol | インドールを抽出分離する方法およびインドール包接分離用薬剤 |
| JPH035438A (ja) * | 1989-05-31 | 1991-01-11 | Kaken Pharmaceut Co Ltd | フルルビプロフェン包接化合物およびこの包接化合物を用いる消炎鎮痛剤 |
| GB8920135D0 (en) * | 1989-09-06 | 1989-10-18 | Erba Carlo Spa | Use of dehydrated cyclodextrins for improving drug dissolution |
| KR0166088B1 (ko) * | 1990-01-23 | 1999-01-15 | . | 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도 |
| HU211648A9 (en) | 1990-03-28 | 1995-12-28 | Chinoin Gyogyszer Es Vegyeszet | Inclusion complexes of 3-morpholino-sydnonimine or its salts or its tautomer isomer, process for the preparation thereof, and pharmaceutical compositions containing the same |
| EP0485614B1 (de) * | 1990-05-21 | 1997-08-13 | Toppan Printing Co., Ltd. | Cyclodextrinderivat |
| US5059699A (en) * | 1990-08-28 | 1991-10-22 | Virginia Tech Intellectual Properties, Inc. | Water soluble derivatives of taxol |
| US5278324A (en) * | 1990-08-28 | 1994-01-11 | Virginia Tech Intellectual Properties, Inc. | Water soluble derivatives of taxol |
| JPH06157330A (ja) * | 1992-11-27 | 1994-06-03 | Ensuiko Sugar Refining Co Ltd | タキソールのサイクロデキストリン包接物，その製造法と用途 |
| JPH0753396A (ja) * | 1993-08-19 | 1995-02-28 | Ensuiko Sugar Refining Co Ltd | タキソールのサイクロデキストリン包接物，その製造法および用途 |
| US5439686A (en) * | 1993-02-22 | 1995-08-08 | Vivorx Pharmaceuticals, Inc. | Methods for in vivo delivery of substantially water insoluble pharmacologically active agents and compositions useful therefor |
-
1993
- 1993-05-12 HU HU9301373A patent/HU213200B/hu unknown
-
1994
- 1994-05-09 JP JP52519794A patent/JP3693341B2/ja not_active Expired - Fee Related
- 1994-05-09 AT AT94918994T patent/ATE225340T1/de active
- 1994-05-09 EP EP94918994A patent/EP0698018B1/de not_active Expired - Lifetime
- 1994-05-09 CA CA002162716A patent/CA2162716C/en not_active Expired - Fee Related
- 1994-05-09 ES ES94918994T patent/ES2184764T3/es not_active Expired - Lifetime
- 1994-05-09 DK DK94918994T patent/DK0698018T3/da active
- 1994-05-09 SK SK1405-95A patent/SK140595A3/sk unknown
- 1994-05-09 CZ CZ952914A patent/CZ291495A3/cs unknown
- 1994-05-09 AU AU70081/94A patent/AU693101B2/en not_active Ceased
- 1994-05-09 PT PT94918994T patent/PT698018E/pt unknown
- 1994-05-09 PL PL94311561A patent/PL311561A1/xx unknown
- 1994-05-09 US US08/545,721 patent/US6284746B1/en not_active Expired - Fee Related
- 1994-05-09 WO PCT/HU1994/000012 patent/WO1994026728A1/en active IP Right Grant
- 1994-05-09 BR BR9406292A patent/BR9406292A/pt not_active Application Discontinuation
- 1994-05-09 CN CN94192076A patent/CN1123030A/zh active Pending
- 1994-05-09 DE DE69431476T patent/DE69431476T2/de not_active Expired - Lifetime
- 1994-05-10 IL IL109613A patent/IL109613A/xx not_active IP Right Cessation
- 1994-05-12 YU YU26894A patent/YU26894A/sh unknown
-
1995
- 1995-11-10 FI FI955424A patent/FI955424A/fi not_active Application Discontinuation
- 1995-11-10 NO NO954545A patent/NO954545L/no unknown
- 1995-11-10 OA OA60738A patent/OA10323A/en unknown
- 1995-12-08 BG BG100207A patent/BG100207A/bg unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BG100207A (bg) | 1996-05-31 |
| NO954545D0 (no) | 1995-11-10 |
| FI955424A0 (fi) | 1995-11-10 |
| HU213200B (en) | 1997-03-28 |
| HUT68589A (en) | 1995-06-28 |
| WO1994026728A1 (en) | 1994-11-24 |
| FI955424A (fi) | 1995-11-10 |
| IL109613A (en) | 1997-09-30 |
| SK140595A3 (en) | 1996-10-02 |
| YU26894A (sh) | 1997-05-28 |
| IL109613A0 (en) | 1994-08-26 |
| CN1123030A (zh) | 1996-05-22 |
| OA10323A (en) | 1997-10-07 |
| ES2184764T3 (es) | 2003-04-16 |
| PL311561A1 (en) | 1996-02-19 |
| PT698018E (pt) | 2003-02-28 |
| DE69431476D1 (de) | 2002-11-07 |
| JPH08510232A (ja) | 1996-10-29 |
| BR9406292A (pt) | 1995-12-26 |
| DE69431476T2 (de) | 2003-06-18 |
| NO954545L (no) | 1995-11-10 |
| EP0698018B1 (de) | 2002-10-02 |
| CA2162716A1 (en) | 1994-11-24 |
| CZ291495A3 (en) | 1996-04-17 |
| HU9301373D0 (en) | 1993-09-28 |
| AU7008194A (en) | 1994-12-12 |
| AU693101B2 (en) | 1998-06-25 |
| US6284746B1 (en) | 2001-09-04 |
| EP0698018A1 (de) | 1996-02-28 |
| JP3693341B2 (ja) | 2005-09-07 |
| CA2162716C (en) | 2005-03-08 |
| DK0698018T3 (da) | 2003-02-10 |
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Legal Events
| Date | Code | Title | Description |
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| UEP | Publication of translation of european patent specification |
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