ATE222770T1 - Pharmazeutische zubereitung für die subkutane, intramuskuläre oder intradermale verabreichung von faktor viii - Google Patents

Pharmazeutische zubereitung für die subkutane, intramuskuläre oder intradermale verabreichung von faktor viii

Info

Publication number
ATE222770T1
ATE222770T1 AT95914669T AT95914669T ATE222770T1 AT E222770 T1 ATE222770 T1 AT E222770T1 AT 95914669 T AT95914669 T AT 95914669T AT 95914669 T AT95914669 T AT 95914669T AT E222770 T1 ATE222770 T1 AT E222770T1
Authority
AT
Austria
Prior art keywords
factor viii
factor
subcutaneous
pct
intramuscular
Prior art date
Application number
AT95914669T
Other languages
English (en)
Inventor
Jack Spira
Lars Widlund
Thomas Oesterberg
Brita Sjoestroem
Marianne Mikaelsson
Original Assignee
Biovitrum Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26662019&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE222770(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from SE9401105A external-priority patent/SE9401105D0/
Priority claimed from SE9500036A external-priority patent/SE9500036D0/xx
Application filed by Biovitrum Ab filed Critical Biovitrum Ab
Application granted granted Critical
Publication of ATE222770T1 publication Critical patent/ATE222770T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/37—Factors VIII
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
AT95914669T 1994-03-31 1995-03-31 Pharmazeutische zubereitung für die subkutane, intramuskuläre oder intradermale verabreichung von faktor viii ATE222770T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9401105A SE9401105D0 (sv) 1993-07-05 1994-03-31 Formulation
SE9500036A SE9500036D0 (sv) 1995-01-05 1995-01-05 Formulation
PCT/SE1995/000348 WO1995026750A1 (en) 1994-03-31 1995-03-31 Pharmaceutical formulation for subcutaneous, intramuscular or intradermal administration of factor viii or factor ix

Publications (1)

Publication Number Publication Date
ATE222770T1 true ATE222770T1 (de) 2002-09-15

Family

ID=26662019

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95914669T ATE222770T1 (de) 1994-03-31 1995-03-31 Pharmazeutische zubereitung für die subkutane, intramuskuläre oder intradermale verabreichung von faktor viii

Country Status (19)

Country Link
US (1) US5925739A (de)
EP (1) EP0772452B1 (de)
JP (1) JP3939750B2 (de)
AT (1) ATE222770T1 (de)
AU (1) AU690666B2 (de)
BR (1) BRPI9507227B8 (de)
CA (1) CA2186126C (de)
DE (1) DE69527966T2 (de)
DK (1) DK0772452T3 (de)
ES (1) ES2182899T3 (de)
FI (1) FI118171B (de)
HU (1) HU223314B1 (de)
IL (2) IL113010A0 (de)
NO (1) NO321139B1 (de)
NZ (1) NZ283499A (de)
PL (1) PL180282B1 (de)
PT (1) PT772452E (de)
TW (1) TW400234B (de)
WO (1) WO1995026750A1 (de)

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SE9502285D0 (sv) 1995-06-22 1995-06-22 Pharmacia Ab Improvements related to injections
US5770700A (en) * 1996-01-25 1998-06-23 Genetics Institute, Inc. Liquid factor IX formulations
ES2243994T5 (es) * 1996-04-19 2009-10-29 Grifols Inc. Procedimiento para la inactivacion virica de proteinas de la sangre liofilizadas.
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US6310183B1 (en) * 1997-09-10 2001-10-30 Novo Nordisk A/S Coagulation factor VIIa composition
US7786070B2 (en) 1997-09-10 2010-08-31 Novo Nordisk Healthcare A/G Subcutaneous administration of coagulation factor VII
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CA2362927C (en) 1999-02-22 2011-07-12 University Of Connecticut Novel albumin-free factor viii formulations
US20020156453A1 (en) * 1999-10-14 2002-10-24 Pettis Ronald J. Method and device for reducing therapeutic dosage
US8465468B1 (en) 2000-06-29 2013-06-18 Becton, Dickinson And Company Intradermal delivery of substances
JP4663837B2 (ja) * 1999-12-24 2011-04-06 一般財団法人化学及血清療法研究所 第▲ｖｉｉｉ▼因子を主成分とする血小板減少に伴う出血疾患の予防・治療用医薬組成物
US20020123093A1 (en) 2000-04-06 2002-09-05 Zannis Vassilis I. Compounds and methods for lowering cholesterol levels without inducing hypertrigylceridemia
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KR20040065278A (ko) * 2001-12-21 2004-07-21 노보 노르디스크 에이/에스 변경된 인자 ⅶ 폴리펩티드의 액체 조성물
US20040009918A1 (en) * 2002-05-03 2004-01-15 Hanne Nedergaard Stabilised solid compositions of modified factor VII
CA2490342C (en) 2002-06-21 2015-06-16 Novo Nordisk A/S Stabilised solid compositions of factor vii polypeptides
MXPA05009914A (es) * 2003-03-18 2006-01-09 Novo Nordisk Healthcare Ag Composiciones farmaceuticas acuosas, liquidas de polipeptidos del factor vii.
US7897734B2 (en) * 2003-03-26 2011-03-01 Novo Nordisk Healthcare Ag Method for the production of proteins
SG155777A1 (en) 2003-04-09 2009-10-29 Neose Technologies Inc Glycopegylation methods and proteins/peptides produced by the methods
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WO2004112828A1 (en) * 2003-06-25 2004-12-29 Novo Nordisk Health Care Ag Liquid composition of factor vii polypeptides
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US9005625B2 (en) 2003-07-25 2015-04-14 Novo Nordisk A/S Antibody toxin conjugates
ES2574581T3 (es) 2003-08-14 2016-06-20 Novo Nordisk Health Care Ag Composición farmacéutica líquida acuosa de polipéptidos de tipo Factor VII
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ES2895798T3 (es) 2014-06-06 2022-02-22 Octapharma Ag Preparación que comprende péptidos del factor VIII y del factor Von Willebrand
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Also Published As

Publication number Publication date
BRPI9507227B8 (pt) 2015-12-08
PL180282B1 (pl) 2001-01-31
CA2186126A1 (en) 1995-10-12
HU223314B1 (hu) 2004-05-28
WO1995026750A1 (en) 1995-10-12
FI963871A (fi) 1996-09-27
HU9602693D0 (en) 1996-11-28
NZ283499A (en) 1997-08-22
BR9507227A (pt) 1997-09-09
JP3939750B2 (ja) 2007-07-04
NO964081D0 (no) 1996-09-27
ES2182899T3 (es) 2003-03-16
AU2156095A (en) 1995-10-23
NO964081L (no) 1996-11-29
MX9604455A (es) 1997-07-31
PT772452E (pt) 2003-01-31
NO321139B1 (no) 2006-03-27
IL113010A0 (en) 1995-10-31
DK0772452T3 (da) 2003-01-06
PL316618A1 (en) 1997-01-20
FI963871A0 (fi) 1996-09-27
TW400234B (en) 2000-08-01
EP0772452B1 (de) 2002-08-28
HUT74918A (en) 1997-03-28
FI118171B (fi) 2007-08-15
DE69527966T2 (de) 2003-05-28
AU690666B2 (en) 1998-04-30
CA2186126C (en) 2007-11-20
JPH10501522A (ja) 1998-02-10
US5925739A (en) 1999-07-20
EP0772452A1 (de) 1997-05-14
DE69527966D1 (de) 2002-10-02
IL113010A (en) 1999-10-28

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