ATE205213T1 - Pentacyclische verbindungen - Google Patents
Pentacyclische verbindungenInfo
- Publication number
- ATE205213T1 ATE205213T1 AT96912252T AT96912252T ATE205213T1 AT E205213 T1 ATE205213 T1 AT E205213T1 AT 96912252 T AT96912252 T AT 96912252T AT 96912252 T AT96912252 T AT 96912252T AT E205213 T1 ATE205213 T1 AT E205213T1
- Authority
- AT
- Austria
- Prior art keywords
- group
- hydrogen atom
- alkynyl
- alkyl
- alkenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Epoxy Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10629595 | 1995-04-28 | ||
PCT/JP1996/001145 WO1996033998A1 (fr) | 1995-04-28 | 1996-04-25 | Composes pentacycliques |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE205213T1 true ATE205213T1 (de) | 2001-09-15 |
Family
ID=14430058
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT96912252T ATE205213T1 (de) | 1995-04-28 | 1996-04-25 | Pentacyclische verbindungen |
Country Status (16)
Country | Link |
---|---|
US (4) | US6075140A (de) |
EP (1) | EP0826688B1 (de) |
KR (1) | KR100380875B1 (de) |
CN (1) | CN1094940C (de) |
AT (1) | ATE205213T1 (de) |
BR (1) | BR9608040B1 (de) |
CA (1) | CA2219675C (de) |
DE (1) | DE69615016T2 (de) |
DK (1) | DK0826688T3 (de) |
EA (1) | EA000701B1 (de) |
ES (1) | ES2164241T3 (de) |
HK (1) | HK1008529A1 (de) |
NO (1) | NO321942B1 (de) |
PT (1) | PT826688E (de) |
TW (1) | TW480262B (de) |
WO (1) | WO1996033998A1 (de) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9425138D0 (en) * | 1994-12-12 | 1995-02-08 | Dynal As | Isolation of nucleic acid |
ES2164241T3 (es) | 1995-04-28 | 2002-02-16 | Daiichi Seiyaku Co | Compuestos pentaciclicos. |
US6458373B1 (en) * | 1997-01-07 | 2002-10-01 | Sonus Pharmaceuticals, Inc. | Emulsion vehicle for poorly soluble drugs |
WO2000044928A2 (en) * | 1999-01-27 | 2000-08-03 | Halaka Folim G | Materials and methods for the purification of polyelectrolytes |
MXPA02003797A (es) * | 1999-10-15 | 2002-12-13 | Daiichi Seiyaku Co | Compuestos de taxano pentaciclico. |
US6677456B2 (en) | 1999-10-15 | 2004-01-13 | Daiichi Pharmaceutical Co., Ltd. | Pentacyclic taxan compound |
NZ520402A (en) * | 2000-01-19 | 2006-04-28 | Cadila Healthcare Ltd | Novel compounds having hypolipedemic, hypocholesteremic activites, process for their preparation and pharmaceutical compositions containing them |
US6362217B2 (en) * | 2000-03-17 | 2002-03-26 | Bristol-Myers Squibb Company | Taxane anticancer agents |
US6987123B2 (en) | 2001-07-26 | 2006-01-17 | Cadila Healthcare Limited | Heterocyclic compounds, their preparation, pharmaceutical compositions containing them and their use in medicine |
EP1457492B1 (de) * | 2001-11-29 | 2008-01-02 | Daiichi Sankyo Company, Limited | Kristalle von taxanderivaten und verfahren zu deren herstellung |
US6787659B2 (en) | 2001-12-11 | 2004-09-07 | Barr Laboratories, Inc. | Process for the production of oxandrolone |
JP2005538929A (ja) | 2002-01-16 | 2005-12-22 | ダイナル バイオテック エイエスエイ | 単一サンプルからの核酸及びタンパク質の単離方法 |
DK1741716T3 (da) * | 2004-04-30 | 2011-11-28 | Daiichi Sankyo Co Ltd | Fremgangsmåde til fremstilling af pentacyklisk taxan |
US20090186868A1 (en) * | 2005-10-25 | 2009-07-23 | Daiichi Sankyo Company Limited | Taxane Compound Having Azetidine Ring Structure |
CN100516067C (zh) | 2006-01-10 | 2009-07-22 | 上海恒瑞医药有限公司 | 具有抗肿瘤活性的紫杉酚衍生物 |
US8785669B2 (en) | 2010-06-30 | 2014-07-22 | Gfv, Llc | Taxane compounds, compositions and methods |
US8697892B2 (en) | 2010-06-30 | 2014-04-15 | Gfv, Llc | Taxane compounds, compositions and methods |
MY191100A (en) | 2011-01-31 | 2022-05-30 | Cadila Healthcare Ltd | Treatment for lipodystrophy |
WO2014174524A1 (en) | 2013-04-22 | 2014-10-30 | Cadila Healthcare Limited | A novel composition for nonalcoholic fatty liver disease (nafld) |
EP3004053B1 (de) | 2013-05-30 | 2021-03-24 | Cadila Healthcare Limited | Verfahren zur herstellung von pyrrolen mit hypolipidämischer hypocholesterämischer aktivität |
TW201513857A (zh) | 2013-07-05 | 2015-04-16 | Cadila Healthcare Ltd | 協同性組成物 |
IN2013MU02470A (de) | 2013-07-25 | 2015-06-26 | Cadila Healthcare Ltd | |
WO2015033357A2 (en) | 2013-09-06 | 2015-03-12 | Cadila Healthcare Limited | An improved process for the preparation of pyrrole derivatives |
WO2017064635A2 (en) | 2015-10-14 | 2017-04-20 | Cadila Healthcare Limited | Pyrrole compound, compositions and process for preparation thereof |
JP6840853B2 (ja) | 2016-12-09 | 2021-03-10 | カディラ・ヘルスケア・リミテッド | 原発性胆汁性胆管炎の治療 |
CN107188895B (zh) * | 2017-04-17 | 2020-03-13 | 上海大学 | C-13和c-14位结构改造的紫杉醇类化合物及其制备方法 |
CN108530400B (zh) * | 2018-05-28 | 2022-07-12 | 上海大学 | C-2位和c-4位修饰的1-去氧紫杉烷类化合物及其制备方法 |
CN110105368B (zh) * | 2019-05-09 | 2022-01-07 | 上海大学 | 去氧紫杉烷类似物及其制备方法 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5481010A (en) * | 1991-07-16 | 1996-01-02 | Centre National De La Recherche Scientifique | 7-deacetoxy beccatine IV derivative and preparation and use thereof |
US5284865A (en) * | 1991-09-23 | 1994-02-08 | Holton Robert A | Cyclohexyl substituted taxanes and pharmaceutical compositions containing them |
WO1993021173A1 (en) * | 1992-04-17 | 1993-10-28 | Abbott Laboratories | Taxol derivatives |
AU656475B2 (en) * | 1992-07-01 | 1995-02-02 | Bristol-Myers Squibb Company | Fluoro taxols |
US5254580A (en) * | 1993-01-19 | 1993-10-19 | Bristol-Myers Squibb Company | 7,8-cyclopropataxanes |
JP3208517B2 (ja) * | 1992-07-01 | 2001-09-17 | ブリストル−マイヤーズ スクイブ カンパニー | 7,8−シクロプロパタキサン類 |
PT1228759E (pt) * | 1993-03-22 | 2005-04-29 | Univ Florida State | Composicoes farmaceuticas contendo um taxano possuindo uma cadeia lateral substituida com furilo ou tienilo |
US5475011A (en) * | 1993-03-26 | 1995-12-12 | The Research Foundation Of State University Of New York | Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment |
FR2711370B1 (fr) * | 1993-10-18 | 1996-01-05 | Rhone Poulenc Rorer Sa | Nouveaux taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent. |
FR2712289B1 (fr) * | 1993-11-08 | 1996-01-05 | Rhone Poulenc Rorer Sa | Nouveaux dérivés de taxicine, leur préparation et les compositions pharmaceutiques qui les contiennent. |
FR2723094A1 (fr) * | 1994-07-26 | 1996-02-02 | Rhone Poulenc Rorer Sa | Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent |
ES2164241T3 (es) * | 1995-04-28 | 2002-02-16 | Daiichi Seiyaku Co | Compuestos pentaciclicos. |
US5780653A (en) * | 1995-06-07 | 1998-07-14 | Vivorx Pharmaceuticals, Inc. | Nitrophenyl, 10-deacetylated substituted taxol derivatives as dual functional cytotoxic/radiosensitizers |
-
1996
- 1996-04-25 ES ES96912252T patent/ES2164241T3/es not_active Expired - Lifetime
- 1996-04-25 WO PCT/JP1996/001145 patent/WO1996033998A1/ja active IP Right Grant
- 1996-04-25 EP EP96912252A patent/EP0826688B1/de not_active Expired - Lifetime
- 1996-04-25 DK DK96912252T patent/DK0826688T3/da active
- 1996-04-25 TW TW085104983A patent/TW480262B/zh not_active IP Right Cessation
- 1996-04-25 CA CA002219675A patent/CA2219675C/en not_active Expired - Fee Related
- 1996-04-25 PT PT96912252T patent/PT826688E/pt unknown
- 1996-04-25 KR KR1019970707705A patent/KR100380875B1/ko not_active IP Right Cessation
- 1996-04-25 CN CN96194915A patent/CN1094940C/zh not_active Expired - Fee Related
- 1996-04-25 DE DE69615016T patent/DE69615016T2/de not_active Expired - Lifetime
- 1996-04-25 US US08/945,276 patent/US6075140A/en not_active Expired - Lifetime
- 1996-04-25 BR BRPI9608040-0A patent/BR9608040B1/pt not_active IP Right Cessation
- 1996-04-25 EA EA199700351A patent/EA000701B1/ru not_active IP Right Cessation
- 1996-04-25 AT AT96912252T patent/ATE205213T1/de active
-
1997
- 1997-10-24 NO NO19974912A patent/NO321942B1/no not_active IP Right Cessation
-
1998
- 1998-07-28 HK HK98109471A patent/HK1008529A1/xx not_active IP Right Cessation
-
2000
- 2000-02-25 US US09/513,852 patent/US6211363B1/en not_active Expired - Lifetime
-
2001
- 2001-01-16 US US09/759,378 patent/US6545151B2/en not_active Expired - Lifetime
-
2002
- 2002-04-22 US US10/126,653 patent/US6646123B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
NO321942B1 (no) | 2006-07-24 |
EP0826688A4 (de) | 1998-05-13 |
US6545151B2 (en) | 2003-04-08 |
KR19990008180A (ko) | 1999-01-25 |
ES2164241T3 (es) | 2002-02-16 |
DE69615016T2 (de) | 2002-05-02 |
EA000701B1 (ru) | 2000-02-28 |
PT826688E (pt) | 2002-02-28 |
NO974912D0 (no) | 1997-10-24 |
EP0826688B1 (de) | 2001-09-05 |
CN1094940C (zh) | 2002-11-27 |
AU704198B2 (en) | 1999-04-15 |
NO974912L (no) | 1997-12-29 |
BR9608040B1 (pt) | 2010-02-23 |
US20030162971A1 (en) | 2003-08-28 |
TW480262B (en) | 2002-03-21 |
US6211363B1 (en) | 2001-04-03 |
BR9608040A (pt) | 1999-01-12 |
DK0826688T3 (da) | 2001-10-22 |
KR100380875B1 (ko) | 2003-10-10 |
EA199700351A1 (ru) | 1998-04-30 |
US6646123B2 (en) | 2003-11-11 |
CA2219675C (en) | 2009-08-18 |
CN1188477A (zh) | 1998-07-22 |
HK1008529A1 (en) | 1999-07-16 |
US20010041796A1 (en) | 2001-11-15 |
US6075140A (en) | 2000-06-13 |
EP0826688A1 (de) | 1998-03-04 |
DE69615016D1 (de) | 2001-10-11 |
WO1996033998A1 (fr) | 1996-10-31 |
AU5514596A (en) | 1996-11-18 |
CA2219675A1 (en) | 1996-10-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |