ATE205213T1 - Pentacyclische verbindungen - Google Patents

Pentacyclische verbindungen

Info

Publication number
ATE205213T1
ATE205213T1 AT96912252T AT96912252T ATE205213T1 AT E205213 T1 ATE205213 T1 AT E205213T1 AT 96912252 T AT96912252 T AT 96912252T AT 96912252 T AT96912252 T AT 96912252T AT E205213 T1 ATE205213 T1 AT E205213T1
Authority
AT
Austria
Prior art keywords
group
hydrogen atom
alkynyl
alkyl
alkenyl
Prior art date
Application number
AT96912252T
Other languages
English (en)
Inventor
Hirofumi Terasawa
Tsunehiko Soga
Takashi Ishiyama
Original Assignee
Daiichi Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=14430058&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE205213(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Daiichi Seiyaku Co filed Critical Daiichi Seiyaku Co
Application granted granted Critical
Publication of ATE205213T1 publication Critical patent/ATE205213T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AT96912252T 1995-04-28 1996-04-25 Pentacyclische verbindungen ATE205213T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP10629595 1995-04-28
PCT/JP1996/001145 WO1996033998A1 (fr) 1995-04-28 1996-04-25 Composes pentacycliques

Publications (1)

Publication Number Publication Date
ATE205213T1 true ATE205213T1 (de) 2001-09-15

Family

ID=14430058

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96912252T ATE205213T1 (de) 1995-04-28 1996-04-25 Pentacyclische verbindungen

Country Status (16)

Country Link
US (4) US6075140A (de)
EP (1) EP0826688B1 (de)
KR (1) KR100380875B1 (de)
CN (1) CN1094940C (de)
AT (1) ATE205213T1 (de)
BR (1) BR9608040B1 (de)
CA (1) CA2219675C (de)
DE (1) DE69615016T2 (de)
DK (1) DK0826688T3 (de)
EA (1) EA000701B1 (de)
ES (1) ES2164241T3 (de)
HK (1) HK1008529A1 (de)
NO (1) NO321942B1 (de)
PT (1) PT826688E (de)
TW (1) TW480262B (de)
WO (1) WO1996033998A1 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9425138D0 (en) 1994-12-12 1995-02-08 Dynal As Isolation of nucleic acid
CN1094940C (zh) 1995-04-28 2002-11-27 第一制药株式会社 具有抗肿瘤活性的紫杉酚衍生物
US6458373B1 (en) * 1997-01-07 2002-10-01 Sonus Pharmaceuticals, Inc. Emulsion vehicle for poorly soluble drugs
AU2862100A (en) * 1999-01-27 2000-08-18 Folim G. Halaka Materials and methods for the purification of polyelectrolytes
US6677456B2 (en) 1999-10-15 2004-01-13 Daiichi Pharmaceutical Co., Ltd. Pentacyclic taxan compound
DE60039998D1 (de) * 1999-10-15 2008-10-02 Daiichi Sankyo Co Ltd Pentacyclische taxan-verbindungen
HU230609B1 (hu) * 2000-01-19 2017-03-28 Cadila Healthcare Ltd. Hipolipidémiás és hipokoleszterinémiás hatású szubsztituált pirrolszármazékok, azokat tartalmazó gyógyszerkészítmények, eljárás előállításukra, köztitermékek és alkalmazásuk
US6362217B2 (en) * 2000-03-17 2002-03-26 Bristol-Myers Squibb Company Taxane anticancer agents
US6987123B2 (en) 2001-07-26 2006-01-17 Cadila Healthcare Limited Heterocyclic compounds, their preparation, pharmaceutical compositions containing them and their use in medicine
DE60224440T2 (de) * 2001-11-29 2009-01-02 Daiichi Sankyo Co., Ltd. Kristalle von taxanderivaten und verfahren zu deren herstellung
US6787659B2 (en) * 2001-12-11 2004-09-07 Barr Laboratories, Inc. Process for the production of oxandrolone
JP2005538929A (ja) 2002-01-16 2005-12-22 ダイナル バイオテック エイエスエイ 単一サンプルからの核酸及びタンパク質の単離方法
ATE526332T1 (de) * 2004-04-30 2011-10-15 Daiichi Seiyaku Co Verfahren zur herstellung von pentacyclischem taxan
US20090186868A1 (en) * 2005-10-25 2009-07-23 Daiichi Sankyo Company Limited Taxane Compound Having Azetidine Ring Structure
CN100516067C (zh) * 2006-01-10 2009-07-22 上海恒瑞医药有限公司 具有抗肿瘤活性的紫杉酚衍生物
US8697892B2 (en) 2010-06-30 2014-04-15 Gfv, Llc Taxane compounds, compositions and methods
US8785669B2 (en) 2010-06-30 2014-07-22 Gfv, Llc Taxane compounds, compositions and methods
MY191100A (en) 2011-01-31 2022-05-30 Cadila Healthcare Ltd Treatment for lipodystrophy
SG11201506218UA (en) 2013-04-22 2015-09-29 Cadila Healthcare Ltd A novel composition for nonalcoholic fatty liver disease (nafld)
WO2014195967A2 (en) 2013-05-30 2014-12-11 Cadila Healthcare Limited A process for preparation of pyrroles having hypolipidemic hypocholesteremic activities
TW201513857A (zh) 2013-07-05 2015-04-16 Cadila Healthcare Ltd 協同性組成物
IN2013MU02470A (de) 2013-07-25 2015-06-26 Cadila Healthcare Ltd
IN2013MU02905A (de) 2013-09-06 2015-07-03 Cadila Healthcare Ltd
WO2017064635A2 (en) 2015-10-14 2017-04-20 Cadila Healthcare Limited Pyrrole compound, compositions and process for preparation thereof
WO2018104916A1 (en) 2016-12-09 2018-06-14 Cadila Healthcare Limited Treatment for primary biliary cholangitis
CN107188895B (zh) * 2017-04-17 2020-03-13 上海大学 C-13和c-14位结构改造的紫杉醇类化合物及其制备方法
CN108530400B (zh) * 2018-05-28 2022-07-12 上海大学 C-2位和c-4位修饰的1-去氧紫杉烷类化合物及其制备方法
CN110105368B (zh) * 2019-05-09 2022-01-07 上海大学 去氧紫杉烷类似物及其制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5481010A (en) * 1991-07-16 1996-01-02 Centre National De La Recherche Scientifique 7-deacetoxy beccatine IV derivative and preparation and use thereof
US5284864A (en) * 1991-09-23 1994-02-08 Florida State University Butenyl substituted taxanes and pharmaceutical compositions containing them
EP0639186B1 (de) * 1992-04-17 1999-06-23 Abbott Laboratories Taxol-derivate
NO302520B1 (no) * 1992-07-01 1998-03-16 Bristol Myers Squibb Co Fluortaxoler, mellomprodukt til fremstilling derav, samt farmasöytisk preparat inneholdende dem
US5254580A (en) * 1993-01-19 1993-10-19 Bristol-Myers Squibb Company 7,8-cyclopropataxanes
JP3208517B2 (ja) * 1992-07-01 2001-09-17 ブリストル−マイヤーズ スクイブ カンパニー ７，８−シクロプロパタキサン類
PT1227093E (pt) * 1993-03-22 2005-09-30 Univ Florida State Beta-cactamas uteis para a preparacao de taxanos possuindo cadeia lateral substituida com furilo ou tienilo
US5475011A (en) * 1993-03-26 1995-12-12 The Research Foundation Of State University Of New York Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment
FR2711370B1 (fr) * 1993-10-18 1996-01-05 Rhone Poulenc Rorer Sa Nouveaux taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
FR2712289B1 (fr) * 1993-11-08 1996-01-05 Rhone Poulenc Rorer Sa Nouveaux dérivés de taxicine, leur préparation et les compositions pharmaceutiques qui les contiennent.
FR2723094A1 (fr) * 1994-07-26 1996-02-02 Rhone Poulenc Rorer Sa Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
CN1094940C (zh) * 1995-04-28 2002-11-27 第一制药株式会社 具有抗肿瘤活性的紫杉酚衍生物
US5780653A (en) * 1995-06-07 1998-07-14 Vivorx Pharmaceuticals, Inc. Nitrophenyl, 10-deacetylated substituted taxol derivatives as dual functional cytotoxic/radiosensitizers

Also Published As

Publication number Publication date
CA2219675A1 (en) 1996-10-31
KR100380875B1 (ko) 2003-10-10
EP0826688B1 (de) 2001-09-05
ES2164241T3 (es) 2002-02-16
EA199700351A1 (ru) 1998-04-30
AU5514596A (en) 1996-11-18
CN1188477A (zh) 1998-07-22
BR9608040A (pt) 1999-01-12
NO974912L (no) 1997-12-29
DE69615016T2 (de) 2002-05-02
US6211363B1 (en) 2001-04-03
WO1996033998A1 (fr) 1996-10-31
HK1008529A1 (en) 1999-07-16
BR9608040B1 (pt) 2010-02-23
DE69615016D1 (de) 2001-10-11
US20030162971A1 (en) 2003-08-28
TW480262B (en) 2002-03-21
CA2219675C (en) 2009-08-18
EA000701B1 (ru) 2000-02-28
KR19990008180A (ko) 1999-01-25
EP0826688A1 (de) 1998-03-04
CN1094940C (zh) 2002-11-27
EP0826688A4 (de) 1998-05-13
DK0826688T3 (da) 2001-10-22
NO321942B1 (no) 2006-07-24
US6545151B2 (en) 2003-04-08
PT826688E (pt) 2002-02-28
US6075140A (en) 2000-06-13
US6646123B2 (en) 2003-11-11
NO974912D0 (no) 1997-10-24
US20010041796A1 (en) 2001-11-15
AU704198B2 (en) 1999-04-15

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Legal Events

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UEP Publication of translation of european patent specification