ATE204874T1 - Spirocyclische und bicyclische diazinyl- und carbazinyloxazolidinone - Google Patents

Spirocyclische und bicyclische diazinyl- und carbazinyloxazolidinone

Info

Publication number
ATE204874T1
ATE204874T1 AT96911768T AT96911768T ATE204874T1 AT E204874 T1 ATE204874 T1 AT E204874T1 AT 96911768 T AT96911768 T AT 96911768T AT 96911768 T AT96911768 T AT 96911768T AT E204874 T1 ATE204874 T1 AT E204874T1
Authority
AT
Austria
Prior art keywords
pct
carbazinyloxazolidinones
spirocyclic
date nov
sec
Prior art date
Application number
AT96911768T
Other languages
English (en)
Inventor
Michael Robert Barbachyn
Steven J Brickner
Douglas K Hutchinson
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Application granted granted Critical
Publication of ATE204874T1 publication Critical patent/ATE204874T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/54—Spiro-condensed
AT96911768T 1995-05-11 1996-04-18 Spirocyclische und bicyclische diazinyl- und carbazinyloxazolidinone ATE204874T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US43870595A 1995-05-11 1995-05-11
PCT/US1996/005202 WO1996035691A1 (en) 1995-05-11 1996-04-18 Spirocyclic and bicyclic diazinyl and carbazinyl oxazolidinones

Publications (1)

Publication Number Publication Date
ATE204874T1 true ATE204874T1 (de) 2001-09-15

Family

ID=23741700

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96911768T ATE204874T1 (de) 1995-05-11 1996-04-18 Spirocyclische und bicyclische diazinyl- und carbazinyloxazolidinone

Country Status (18)

Country Link
US (1) US6090820A (de)
EP (1) EP0828741B1 (de)
JP (1) JPH11506430A (de)
KR (1) KR100463771B1 (de)
CN (2) CN1068328C (de)
AT (1) ATE204874T1 (de)
AU (1) AU702752B2 (de)
CA (1) CA2218088A1 (de)
DE (1) DE69614847T2 (de)
DK (1) DK0828741T3 (de)
ES (1) ES2162047T3 (de)
FI (1) FI974180A0 (de)
HK (2) HK1009449A1 (de)
MX (1) MX9708627A (de)
NO (1) NO311298B1 (de)
NZ (1) NZ306310A (de)
PT (1) PT828741E (de)
WO (1) WO1996035691A1 (de)

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GB9601666D0 (en) * 1996-01-27 1996-03-27 Zeneca Ltd Chemical compounds
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GB9609919D0 (en) * 1996-05-11 1996-07-17 Zeneca Ltd Chemical compounds
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KR100463111B1 (ko) * 1997-10-30 2005-06-13 씨제이 주식회사 신규한옥사졸리디논유도체및제조방법및그를함유하는항균제조성물
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US6413981B1 (en) 1999-08-12 2002-07-02 Ortho-Mcneil Pharamceutical, Inc. Bicyclic heterocyclic substituted phenyl oxazolidinone antibacterials, and related compositions and methods
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US6518285B2 (en) 1999-12-21 2003-02-11 Ortho Mcneil Pharmaceutical, Inc. Piperidinyloxy and pyrrolidinyloxy oxazolidinone antibacterials
GB0009803D0 (en) * 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
ITVA20000023A1 (it) * 2000-07-19 2002-01-19 Lamberti Spa Composizioni di pvc stabili al calore.
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EP1368354A1 (de) 2001-03-07 2003-12-10 Pfizer Products Inc. Modulatoren der aktivität von chemokin-rezeptoren
EP1448536A1 (de) 2001-11-29 2004-08-25 Merck & Co., Inc. Cyclopropyl enthaltende oxazolidinonantibiotika und deren derivate
US7141588B2 (en) 2002-02-25 2006-11-28 Pfizer, Inc. N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
AR038536A1 (es) 2002-02-25 2005-01-19 Upjohn Co N-aril-2-oxazolidinona-5- carboxamidas y sus derivados
AU2003259159A1 (en) 2002-08-12 2004-02-25 Pharmacia & Upjohn Company Llc N-aryl-2-oxazolidinones and their derivatives
KR100454099B1 (ko) * 2002-08-22 2004-10-26 한국화학연구원 제초활성을 갖는9-(5-이속사졸린메톡시페닐)이미노-8-치아-1,6-디아자비시클로[4.3.0]노난-7-온 유도체
DE60309504T2 (de) 2002-11-21 2007-05-16 Pharmacia & Upjohn Co. Llc, Kalamazoo N-(4-(piperazin-1-yl)-phenyl-2-oxazolidinon-5-carbosäureamid-derivate und verwandte verbindungen als antibakterielle mittel
EP1646629B1 (de) 2003-07-02 2010-06-23 Merck Sharp & Dohme Corp. Cyclopropylgruppensubstituierte oxazolidinonantibiotika und derivate davon
US7304050B2 (en) 2003-09-16 2007-12-04 Pfizer Inc. Antibacterial agents
EP1846409A1 (de) * 2004-11-24 2007-10-24 Pfizer Limited Octahydropyrrolo[3,4-c]pyrrolderivate
EP1671972A1 (de) * 2004-11-24 2006-06-21 Pfizer Limited Octahydropyrrolo[3,4-c]pyrrol-Derivate
KR100729344B1 (ko) * 2006-02-16 2007-06-15 스마텍(주) 차량용 사방 감지 카메라의 보호 및 작동 구조
US7728031B2 (en) 2006-02-24 2010-06-01 Abbott Laboratories Octahydro-pyrrolo[3,4-b]pyrrole derivatives
EP2188288A1 (de) 2007-09-11 2010-05-26 Abbott Laboratories Octahydropyrrolo[3,4-b]pyrrol-n-oxide
JP5662940B2 (ja) 2008-11-20 2015-02-04 パナセア バイオテック リミテッド 新規な抗微生物薬
RU2012102094A (ru) 2009-06-26 2013-08-10 Панацеа Биотек Лтд. Новые азабициклогексаны
JP2014500247A (ja) 2010-11-03 2014-01-09 ウォックハート リミテッド リン酸モノ−（１−｛４−［（ｓ）―５−（アセチルアミノメチル）−２−オキソ−オキサゾリジン−３−イル］−２，６−ジフルオロフェニル｝−４−メトキシメチルピペリジン−４−イル）エステルの調製方法
KR101271224B1 (ko) * 2011-07-05 2013-06-10 한국과학기술연구원 항균활성을 갖는 신규 이중고리를 포함하는 옥사졸리디논 유도체 및 이의 제조방법
JP5833764B2 (ja) 2011-09-30 2015-12-16 山東軒竹医薬科技有限公司 縮合環を有するオキサゾリドン（ｏｘａｚｏｌｉｄｏｎｅ）類の抗菌物質
WO2015173664A1 (en) 2014-05-14 2015-11-19 Wockhardt Limited Process for the preparation of (5s)-n-{3-[3,5-difluoro-4-(4-hydroxy-4-methoxymethyl-piperidin-1-yl)-phenyl]-2-oxo-oxazolidin-5-ylmethyl}-acetamide
AU2016287477B2 (en) 2015-07-02 2021-10-21 Janssen Sciences Ireland Uc Antibacterial compounds
EP3932917A3 (de) * 2015-07-17 2022-03-30 The Global Alliance for TB Drug Development, Inc. Substituierte phenyloxazolidinone für antimikrobielle therapie
CN107400126A (zh) * 2016-05-19 2017-11-28 陕西合成药业股份有限公司 新型噁唑烷酮类化合物及其制备方法和在医学上的应用
MA45377A (fr) * 2016-06-16 2019-04-24 Janssen Sciences Ireland Unlimited Co Composés hétérocycliques en tant qu'agents antibacteriens
MA47676A (fr) 2017-03-01 2021-06-02 Janssen Sciences Ireland Unlimited Co Polythérapie
CN108727406B (zh) 2017-03-28 2021-12-07 北京协和制药二厂 含氮杂环取代的苯并噁嗪噁唑烷酮类化合物及其制备方法和用途
WO2020234636A1 (en) 2019-05-17 2020-11-26 Cadila Healthcare Limited Novel compounds for the treatment of mammalian infections

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US4921869A (en) * 1987-10-09 1990-05-01 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents
CA1320730C (en) * 1987-10-16 1993-07-27 The Du Pont Merck Pharmaceutical Company Aminomethyl oxooxazolidinyl aroylbenzene derivatives useful as antibacterial agents
EP0316594B1 (de) * 1987-10-21 1993-09-29 The Du Pont Merck Pharmaceutical Company Aminomethyl-oxo-oxazolidinyl-ethenylbenzen-Derivate, nützlich als antibakterielles Mittel
US4948801A (en) * 1988-07-29 1990-08-14 E. I. Du Pont De Nemours And Company Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
DE68929303T2 (de) * 1988-09-15 2002-05-02 Upjohn Co 3-(Stickstoff substituierte)phenyl-5-beta-amidomethyloxazoliden-2-one
JP3176626B2 (ja) * 1991-11-01 2001-06-18 ファルマシア・アンド・アップジョン・カンパニー 抗菌剤として有用な置換アリール−およびヘテロアリールフェニルオキサゾリジノン類
SK283420B6 (sk) * 1992-05-08 2003-07-01 Pharmacia & Upjohn Company Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny
MY115155A (en) * 1993-09-09 2003-04-30 Upjohn Co Substituted oxazine and thiazine oxazolidinone antimicrobials.
JPH0873455A (ja) * 1994-03-15 1996-03-19 Upjohn Co:The オキサゾリジノン誘導体及びこれを有効成分とする医薬組成物

Also Published As

Publication number Publication date
AU702752B2 (en) 1999-03-04
ES2162047T3 (es) 2001-12-16
NO975158L (no) 1998-01-09
AU5484996A (en) 1996-11-29
DE69614847D1 (de) 2001-10-04
WO1996035691A1 (en) 1996-11-14
HK1009449A1 (en) 1999-09-10
PT828741E (pt) 2002-02-28
CN1184481A (zh) 1998-06-10
HK1042093A1 (zh) 2002-08-02
NO311298B1 (no) 2001-11-12
JPH11506430A (ja) 1999-06-08
EP0828741A1 (de) 1998-03-18
CN1068328C (zh) 2001-07-11
FI974180A (fi) 1997-11-10
CA2218088A1 (en) 1996-11-14
DK0828741T3 (da) 2001-11-26
KR19990008399A (ko) 1999-01-25
MX9708627A (es) 1998-02-28
US6090820A (en) 2000-07-18
EP0828741B1 (de) 2001-08-29
KR100463771B1 (ko) 2005-05-16
CN1336375A (zh) 2002-02-20
FI974180A0 (fi) 1997-11-10
NO975158D0 (no) 1997-11-10
DE69614847T2 (de) 2002-04-04
NZ306310A (en) 2001-05-25

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Legal Events

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REN Ceased due to non-payment of the annual fee