ATE186552T1 - Menschliches rhinovirusrezeptorprotein, das die virusinfektionsanfälligkeit hemmt - Google Patents

Menschliches rhinovirusrezeptorprotein, das die virusinfektionsanfälligkeit hemmt

Info

Publication number
ATE186552T1
ATE186552T1 AT89115358T AT89115358T ATE186552T1 AT E186552 T1 ATE186552 T1 AT E186552T1 AT 89115358 T AT89115358 T AT 89115358T AT 89115358 T AT89115358 T AT 89115358T AT E186552 T1 ATE186552 T1 AT E186552T1
Authority
AT
Austria
Prior art keywords
receptor
hrv
human rhinovirus
detergent
receptor protein
Prior art date
Application number
AT89115358T
Other languages
English (en)
Inventor
Jeffrey Dr Greve
Alan Dr Mcclelland
Gary Davis
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Application granted granted Critical
Publication of ATE186552T1 publication Critical patent/ATE186552T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70525—ICAM molecules, e.g. CD50, CD54, CD102
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
AT89115358T 1988-09-01 1989-08-19 Menschliches rhinovirusrezeptorprotein, das die virusinfektionsanfälligkeit hemmt ATE186552T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23957188A 1988-09-01 1988-09-01
US26242888A 1988-10-25 1988-10-25
US39066289A 1989-08-10 1989-08-10

Publications (1)

Publication Number Publication Date
ATE186552T1 true ATE186552T1 (de) 1999-11-15

Family

ID=27399251

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89115358T ATE186552T1 (de) 1988-09-01 1989-08-19 Menschliches rhinovirusrezeptorprotein, das die virusinfektionsanfälligkeit hemmt

Country Status (15)

Country Link
US (1) US7132395B1 (de)
EP (1) EP0362531B1 (de)
JP (1) JP3253064B2 (de)
AT (1) ATE186552T1 (de)
AU (1) AU637324B2 (de)
CA (1) CA1339193C (de)
DE (1) DE68929096T2 (de)
DK (1) DK174095B1 (de)
ES (1) ES2141076T3 (de)
FI (1) FI894065A (de)
GR (1) GR3032456T3 (de)
IL (1) IL91454A (de)
NO (1) NO893373L (de)
NZ (1) NZ230474A (de)
PT (1) PT91570B (de)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0303692A4 (en) * 1987-02-26 1990-12-05 Dana Farber Cancer Institute Cloning of lfa-1
US5151267A (en) * 1988-07-15 1992-09-29 University Of Saskatchewan Bovine herpesvirus type 1 polypeptides and vaccines
US5585264A (en) * 1988-07-15 1996-12-17 University Of Saskatchewan Nucleotide sequences encoding recombinant bovine herpesvirus type-1 GI, GIII and GIV polypeptides
US6051231A (en) * 1988-09-01 2000-04-18 Bayer Corporation Antiviral methods and prepations
ATE186552T1 (de) 1988-09-01 1999-11-15 Bayer Ag Menschliches rhinovirusrezeptorprotein, das die virusinfektionsanfälligkeit hemmt
US6514936B1 (en) 1988-09-01 2003-02-04 Bayer Corporation Antiviral methods using human rhinovirus receptor (ICAM-1)
ZA896668B (en) * 1988-09-01 1990-06-27 Molecular Therapeutics Inc A human rhinovirus receptor protein that inhibits virus infectivity
US6143298A (en) * 1988-09-01 2000-11-07 Bayer Corporation Soluble truncated forms of ICAM-1
NO900155L (no) * 1989-01-24 1990-07-25 Molecular Therapeutics Inc Et opploeselig molekyl som er relatert til, men forskjellig fra icam-1.
JPH04505009A (ja) * 1989-03-09 1992-09-03 ダナ・ファーバー・キャンサー・インスティチュート クローニングｌｆａ―１
ATE146968T1 (de) * 1989-03-16 1997-01-15 Blood Res Center Verwendung von funkionellen derivaten des interzellulär-adhäsions-moleküls icam-1 in einer antivirus-therapie
WO1991018010A1 (en) * 1990-05-15 1991-11-28 Swinburne Limited Inhibition of viral infection using intercellular adhesion molecule-1-like peptides and/or analogues thereof
ATE184049T1 (de) * 1990-07-20 1999-09-15 Bayer Ag Multimere formen des menschlichen rhinovirus- rezeptorproteins
US5871733A (en) * 1990-07-20 1999-02-16 Bayer Corporation Multimeric forms of human rhinovirus receptor protein
US6107461A (en) * 1990-07-20 2000-08-22 Bayer Corporation Multimeric forms of human rhinovirus receptor and fragments thereof, and method of use
US5674982A (en) * 1990-07-20 1997-10-07 Bayer Corporation Multimeric form of human rhinovirus receptor protein
US6130202A (en) * 1990-07-20 2000-10-10 Bayer Corporation Antiviral methods
US5288854A (en) * 1990-11-28 1994-02-22 Center For Blood Research, Inc. Functional derivatives of ICAM-1 which are substantially capable of binding to LFA-1 but are substantially incapable of binding to MAC-1
US5629162A (en) * 1991-06-11 1997-05-13 The Center For Blood Research Method of identifying agents which modulate ICAM-3 binding to LFA-1
US6100383A (en) * 1992-01-27 2000-08-08 Icos Corporation Fusion proteins comprising ICAM-R polypeptides and immunoglobulin constant regions
US6818743B1 (en) 1992-01-27 2004-11-16 Icos Corporation I-CAM related protein
WO1993014776A1 (en) * 1992-01-27 1993-08-05 Icos Corporation Icam-related protein
US5773218A (en) * 1992-01-27 1998-06-30 Icos Corporation Method to identify compounds which modulate ICAM-related protein interactions
US6153395A (en) * 1992-01-27 2000-11-28 Icos Corporation ICAM-related protein
US5989843A (en) * 1992-01-27 1999-11-23 Icos Corporation Methods for identifying modulators of protein kinase C phosphorylation of ICAM-related protein
US5837822A (en) * 1992-01-27 1998-11-17 Icos Corporation Humanized antibodies specific for ICAM related protein
US5532127A (en) * 1992-01-27 1996-07-02 Icos Corporation Assay for 1-CAM related protein expression
US5525487A (en) * 1992-01-27 1996-06-11 Icos Corporation DNA encoding I-CAM related protein
AU710965B2 (en) * 1992-06-22 1999-09-30 Bayer Corporation Multimeric forms of human rhinovirus receptor protein
WO1994011400A1 (en) * 1992-11-18 1994-05-26 Helsinki University Licensing Ltd. Oy Peptides from human icam-2 and from human icam-1 and their analogs for use in therapy and diagnosis
GB9414966D0 (en) * 1994-07-26 1994-09-14 Danbiosyst Uk Pharmaceutical compositions for the nasal administration of antiviral agents
US5879712A (en) * 1995-06-07 1999-03-09 Sri International Method for producing drug-loaded microparticles and an ICAM-1 dosage form so produced
WO1997032596A1 (en) * 1996-03-06 1997-09-12 Boehringer Ingelheim Pharmaceuticals, Inc. Intercellular adhesion molecule powder formulation
US6391452B1 (en) 1997-07-18 2002-05-21 Bayer Corporation Compositions for nasal drug delivery, methods of making same, and methods of removing residual solvent from pharmaceutical preparations
PT1682537E (pt) 2003-11-05 2012-06-20 Sarcode Bioscience Inc Moduladores de adesão celular
LT2444079T (lt) 2005-05-17 2017-03-27 Sarcode Bioscience Inc. Kompozicijos ir būdai, skirti akių sutrikimų gydymui
MX2010004281A (es) 2007-10-19 2010-09-10 Sarcode Corp Composiciones y metodos para el tratamiento de la retinopatia diabetica.
WO2009139817A2 (en) 2008-04-15 2009-11-19 Sarcode Corporation Crystalline pharmaceutical and methods of preparation and use thereof
US8378105B2 (en) 2009-10-21 2013-02-19 Sarcode Bioscience Inc. Crystalline pharmaceutical and methods of preparation and use thereof
EP3715345B1 (de) 2012-07-25 2024-04-10 Novartis AG Herstellung eines lfa-1-hemmers
US20170360815A1 (en) 2016-02-25 2017-12-21 Applied Biological Laboratories, Inc. Compositions and methods for protecting against airborne pathogens and irritants
KR20180120204A (ko) 2016-02-25 2018-11-05 어플라이드 바이올로지컬 래버러토리즈 인코포레이티드 공기 매개 병원체 및 자극물질에 대한 보호용 조성물 및 방법

Family Cites Families (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4209526A (en) 1977-08-05 1980-06-24 Sterling Drug Inc. Antiviral arylenedioxyalkyl substituted pyrazoles
US4261928A (en) 1977-08-05 1981-04-14 Sterling Drug Inc. 2-Benzoyl-8-(2-chloro-4-methoxyphenoxy)-1-phenyl-1-octanone
US4171365A (en) 1977-08-05 1979-10-16 Sterling Drug Inc. Antiviral aryloxyalkylpyrazoles
GB2022826A (en) 1978-06-12 1979-12-19 Corning Glass Works Measuring Antigen Receptors on Cell Membranes
US4234725A (en) 1979-10-24 1980-11-18 Sterling Drug Inc. 4-[6-(2-Chloro-4-methoxyphenoxy)hexyl]-3,5-diethyl-1-[4-(4-morpholinyl)-1-oxobutyl]-1H-pyrazole
US4232161A (en) 1979-10-24 1980-11-04 Sterling Drug Inc. 4-[6-(2-Chloro-4-methoxyphenoxy)hexyl]-3,5-diethyl-1-(2-pyridinyl)-1H-pyrazole
US5179017A (en) 1980-02-25 1993-01-12 The Trustees Of Columbia University In The City Of New York Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
US4427653A (en) 1981-01-26 1984-01-24 President And Fellows Of Harvard College Method of making monoclonal antibodies
US4372976A (en) 1981-08-07 1983-02-08 Sterling Drug Inc. Novel aryl-aliphatic ketone and its use as an antiviral agent
US4451476A (en) 1982-12-13 1984-05-29 Sterling Drug Inc. Isoxazoles as antiviral agents
US4843087A (en) 1983-08-29 1989-06-27 Sterling Drug Inc. Di-heterocyclic compounds and their use as antiviral agents
EP0169146A3 (de) * 1984-07-20 1988-07-20 Merck & Co. Inc. Monoklonale Antikörper gegen den Rezeptor des menschlichen Rhinovirus
JPS6181798A (ja) 1984-07-23 1986-04-25 ベクトン・デイツキンソン・アンド・カンパニ− 細胞リセプタ−の回収
DE3505148A1 (de) 1985-02-15 1986-10-30 Boehringer Ingelheim International GmbH, 6507 Ingelheim Polypeptide des rhinovirusstammes hrv2 sowie die hierfuer codierenden dna-molekuele
CA1280753C (en) 1985-07-02 1991-02-26 Philip Michael Carabateas Process for preparing heterocyclic substituted- phenoxyalkyl isoxazoles and-furans
EP0227604A3 (de) 1985-12-23 1989-01-18 Sandoz Ag Verwendung von Oligopeptiden in der Behandlung von viralen Infektionen
EP0261403A3 (de) 1986-08-23 1988-04-13 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Polypeptide des Rhinovirusstammes HRV89 sowie die hierfür codierenden DNA-Moleküle
JPS63276494A (ja) 1987-02-26 1988-11-14 ダナーファーバー・キャンサー・インスチチュート・インコーポレーテッド Ｌｆａ−３の精製法
DE3712678A1 (de) 1987-04-14 1988-10-27 Boehringer Ingelheim Int Rezeptor der kleinen rhinovirus rezeptor gruppe
US5603932A (en) 1987-04-14 1997-02-18 Boehringer Ingelheim International Gmbh Receptor of the minor human rhinovirus receptor group
US5304636A (en) 1987-04-14 1994-04-19 Boehringer Ingelheim International Gmbh Receptor for the human rhinovirus minor group
US5831036A (en) 1987-05-04 1998-11-03 Dana Farber Cancer Institute Soluble fragments of human intercellular adhesion molecule-1
AU629189B2 (en) 1987-05-04 1992-10-01 Dana-Farber Cancer Institute Intercellular adhesion molecules and their binding ligands
ES2080044T3 (es) 1987-05-04 1996-02-01 Dana Farber Cancer Inst Inc Moleculas de adhesion intercelular y sus ligandos de fijacion.
US5284931A (en) 1987-05-04 1994-02-08 Dana Farber Cancer Institute Intercellular adhesion molecules, and their binding ligands
US4956281A (en) 1987-06-03 1990-09-11 Biogen, Inc. DNA sequences, recombinant DNA molecules and processes for producing lymphocyte function associated antigen-3
US5109123A (en) 1988-06-14 1992-04-28 Dana Farber Cancer Institute Alteration of ability of soluble CD4 fragments to bind HIV
DE3852374T2 (de) 1987-11-02 1995-05-04 Baylor College Medicine Verwendung von ICAM-1 oder ihre funktionelle Derivate zur Behandlung unspezifischer Entzündungen.
US5081228A (en) 1988-02-25 1992-01-14 Immunex Corporation Interleukin-1 receptors
CA1341055C (en) * 1987-12-08 2000-07-18 Alan Mcclelland Transfectant cell lines which express the major human rhinovirus receptor
US5395929A (en) 1987-12-15 1995-03-07 Dana Farber Cancer Institute Isolated nucleic acid encoding the alpha subunit of the human leukocyte adhesion receptor
EP0362526B1 (de) 1988-08-23 1995-06-14 Dana Farber Cancer Institute Alpha-Subeinheit des LFA-1-Leukocyt-Adhäsions-Rezeptors
US6514936B1 (en) * 1988-09-01 2003-02-04 Bayer Corporation Antiviral methods using human rhinovirus receptor (ICAM-1)
ZA896668B (en) * 1988-09-01 1990-06-27 Molecular Therapeutics Inc A human rhinovirus receptor protein that inhibits virus infectivity
US6143298A (en) 1988-09-01 2000-11-07 Bayer Corporation Soluble truncated forms of ICAM-1
US6051231A (en) 1988-09-01 2000-04-18 Bayer Corporation Antiviral methods and prepations
ATE186552T1 (de) 1988-09-01 1999-11-15 Bayer Ag Menschliches rhinovirusrezeptorprotein, das die virusinfektionsanfälligkeit hemmt
ES2201052T3 (es) 1988-09-28 2004-03-16 Dana Farber Cancer Institute Moleculas de adhesion intercelular y sus ligandos de union.
US5372933A (en) 1988-10-03 1994-12-13 The Scripps Research Institute Polypeptides that mimic receptor-induced binding sites, and methods of using same
CA2008368C (en) 1989-01-24 2003-04-08 Jeffrey Greve Soluble molecule related to but distinct from icam-1
NO900155L (no) * 1989-01-24 1990-07-25 Molecular Therapeutics Inc Et opploeselig molekyl som er relatert til, men forskjellig fra icam-1.
US5235049A (en) 1989-01-24 1993-08-10 Molecular Therapeutics, Inc. Nucleic acid sequences encoding a soluble molecule (SICAM-1) related to but distinct from ICAM-1
PT92900A (pt) 1989-01-24 1990-07-31 Sistema de vectores de expressao para a producao de anticorpos monoclonais quimericos
DK0387701T3 (da) 1989-03-09 1992-12-07 Boehringer Ingelheim Pharma Anvendelse af intercellulære adhæsionsmolekyler samt deres bindende ligander ved behandling af astma
HU217792B (hu) 1989-03-16 2000-04-28 Dana Farber Cancer Institute Eljárás intercelluláris adhéziós molekula (ICAM-1) oldható származékai és ezeket tartalmazó gyógyszerkészítmények előállítására
ATE146968T1 (de) * 1989-03-16 1997-01-15 Blood Res Center Verwendung von funkionellen derivaten des interzellulär-adhäsions-moleküls icam-1 in einer antivirus-therapie
US5324510A (en) 1989-09-01 1994-06-28 Boehringer Ingelheim Pharmaceuticals, Inc. Use of antibodies to intercellular adhesion molecule-1 (ICAM-1) in the treatment of asthma
EP0459577A3 (en) 1990-06-01 1992-08-05 Merck & Co. Inc. Microbially expressed portions of a monoclonal antibody block rhinovirus attachment to cell receptors
US5349053A (en) 1990-06-01 1994-09-20 Protein Design Labs, Inc. Chimeric ligand/immunoglobulin molecules and their uses
US6130202A (en) * 1990-07-20 2000-10-10 Bayer Corporation Antiviral methods
US5674982A (en) 1990-07-20 1997-10-07 Bayer Corporation Multimeric form of human rhinovirus receptor protein
US5871733A (en) 1990-07-20 1999-02-16 Bayer Corporation Multimeric forms of human rhinovirus receptor protein
US6107461A (en) 1990-07-20 2000-08-22 Bayer Corporation Multimeric forms of human rhinovirus receptor and fragments thereof, and method of use
ATE184049T1 (de) 1990-07-20 1999-09-15 Bayer Ag Multimere formen des menschlichen rhinovirus- rezeptorproteins
AU8631991A (en) 1990-08-27 1992-03-17 Cetus Corporation Cd18 peptide medicaments for the treatment of disease
US5288854A (en) 1990-11-28 1994-02-22 Center For Blood Research, Inc. Functional derivatives of ICAM-1 which are substantially capable of binding to LFA-1 but are substantially incapable of binding to MAC-1
EP0517895B1 (de) 1990-12-14 1996-11-20 Cell Genesys, Inc. Chimärische ketten zur transduktion von rezeptorverbundenen signalwegen
EP0510483A1 (de) 1991-04-22 1992-10-28 Boehringer Ingelheim Pharmaceuticals Inc. Verfahren zum Nachweis von Viren
US5223396A (en) 1991-05-03 1993-06-29 Boehringer Ingelheim Pharmaceuticals, Inc. Method for detecting organ transplant rejection
US5240694A (en) 1991-09-23 1993-08-31 University Of Virginia Combined antiviral and antimediator treatment of common colds
WO1993006865A1 (en) 1991-10-04 1993-04-15 The United States of America, represented by The Secretary, Department of Health & Human Services Treatment of ocular inflammation by blockage of cell adhesion molecules
US5525487A (en) 1992-01-27 1996-06-11 Icos Corporation DNA encoding I-CAM related protein
WO1993014776A1 (en) 1992-01-27 1993-08-05 Icos Corporation Icam-related protein
US5532127A (en) 1992-01-27 1996-07-02 Icos Corporation Assay for 1-CAM related protein expression
PT566554E (pt) 1992-03-13 2000-09-29 Monsanto Co Producao de proteinas recombinantes usando promotores do virus de herpes e transactivadores vp16
AU675441B2 (en) 1992-06-22 1997-02-06 Bayer Corporation Multimeric forms of human rhinovirus receptor protein
US5580969A (en) 1992-07-24 1996-12-03 The United States Of America As Represented By The Secretary Of The Navy Antisense oligonucleotides directed against human ICAM-I RNA
US5879712A (en) 1995-06-07 1999-03-09 Sri International Method for producing drug-loaded microparticles and an ICAM-1 dosage form so produced

Also Published As

Publication number Publication date
DE68929096T2 (de) 2000-05-11
AU4027189A (en) 1990-03-08
JP3253064B2 (ja) 2002-02-04
CA1339193C (en) 1997-08-05
DE68929096D1 (de) 1999-12-16
EP0362531A1 (de) 1990-04-11
NO893373D0 (no) 1989-08-22
NZ230474A (en) 1993-03-26
DK431289A (da) 1990-03-02
DK174095B1 (da) 2002-06-10
IL91454A0 (en) 1990-04-29
US7132395B1 (en) 2006-11-07
JPH02238892A (ja) 1990-09-21
GR3032456T3 (en) 2000-05-31
PT91570B (pt) 1995-05-31
DK431289D0 (da) 1989-08-31
IL91454A (en) 1995-08-31
ES2141076T3 (es) 2000-03-16
EP0362531B1 (de) 1999-11-10
FI894065A (fi) 1990-03-02
NO893373L (no) 1990-03-02
AU637324B2 (en) 1993-05-27
PT91570A (pt) 1990-03-30
FI894065A0 (fi) 1989-08-30

Similar Documents

Publication Publication Date Title
ATE186552T1 (de) Menschliches rhinovirusrezeptorprotein, das die virusinfektionsanfälligkeit hemmt
UA41870C2 (uk) Спосіб направлення клітинної відповіді на інфекційний агент, клітину, інфіковану вказаним агентом, пухлинну, злоякісну клітину або аутоімунну клітину (варіанти), клітина, яка експресує мембранозв'язаний білковий химерний рецептор (варіанти), днк,що кодує химерний рецептор, вектор, спосіб лікування інфекції вірусу імунодефіциту(варіанти)
Hecht et al. Predominance of hemoglobin Gower 1 in early human embryonic development
RU97115895A (ru) Переключение клеточного иммунитета, осуществляемое с помощью тирозин-специфических протеинкиназных химер
ATE98376T1 (de) Synthetische htlv-iii-peptid-zusammensetzungen und ihre verwendung.
AU597698B2 (en) Expression products of human papilloma virus type 18, antibodies specific to these proteins, and diagnostic aids containing these antibodies or corresponding DNA
DE69232906T2 (de) Detektion des Hepatis-C Virus.
KR890002547A (ko) Hiv 감염의 치료 및 진단용 모노클로날항체 및 펩티드
DE3872754D1 (de) Nachweis von antikoerpern humaner immundefizienz-viren.
ATE125870T1 (de) Hiv-spezifische monoklonale antikörper und hybridome zu ihrer herstellung.
OA09026A (en) Method for detecting antibodies to human immunodeficiency virus.
Iversen et al. The major internal protein, p27, of a retrovirus-like particle is expressed in blood lymphocytes from psoriatic patients
DE3889945T2 (de) Methoden und Materialien für die HIV-Erkennung und Therapie.
FR2655269B1 (fr) Proteines empechant l'interaction entre un fragment fc d'une immunoglobuline et son recepteur et utilisation en therapeutique, notamment dans le traitement des affections liees aux virus hiv.
Frenzel et al. Purification of a glycoprotein from bovine leukemia virus (BLV)
Papamichail et al. Binding of native and aggregated human γ-globulin by mouse lymphoid cells and fibroblasts
Koethe et al. Lysis of Neuraminidase-Treated Paroxysmal Nocturnal Hemoglobinuria (PNH) Erythrocytes in Normal Human Serum
RU95122100A (ru) Способ иммунокоррекции носителя патогена
Kukaine et al. Induction of bovine leukemia C-type oncornaviruses
SU1207004A1 (ru) Способ прогнозирования эндомиометрита после операции кесарева сечения
Zhang et al. AChR specific T lymphocytes in Myasthenia Gravis
DE68913872D1 (de) Monoklonale Antikörper gegen den menschlichen Epidermal-Wachstumsfaktor mit hohem Molekulargewicht.
RU97107909A (ru) Штамм гибридных культивируемых клеток животного rattus norvegicus, используемый для получения моноклональных антител к вирусу гепатита а человека
RU98105411A (ru) Способ получения препарата альфа-фетопротеина
SU1533329A1 (ru) Штамм гибридных культивируемых клеток животных mus musculus, используемый для получения моноклональных антител к белку е оболочки вирусов комплекса клещевого энцефалита

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time