AU597698B2 - Expression products of human papilloma virus type 18, antibodies specific to these proteins, and diagnostic aids containing these antibodies or corresponding DNA - Google Patents

Expression products of human papilloma virus type 18, antibodies specific to these proteins, and diagnostic aids containing these antibodies or corresponding DNA

Info

Publication number
AU597698B2
AU597698B2 AU76018/87A AU7601887A AU597698B2 AU 597698 B2 AU597698 B2 AU 597698B2 AU 76018/87 A AU76018/87 A AU 76018/87A AU 7601887 A AU7601887 A AU 7601887A AU 597698 B2 AU597698 B2 AU 597698B2
Authority
AU
Australia
Prior art keywords
antibodies
proteins
virus type
papilloma virus
expression products
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU76018/87A
Other versions
AU7601887A (en
Inventor
Matthias Durst
Tilmann Oltersdorf
Walter Rowekamp
Ansbert Schneider-Gadicke
Elisabeth Schwarz
Klaus Seedorf
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics GmbH Germany
Original Assignee
Behringwerke AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke AG filed Critical Behringwerke AG
Publication of AU7601887A publication Critical patent/AU7601887A/en
Application granted granted Critical
Publication of AU597698B2 publication Critical patent/AU597698B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
    • C07K16/084—Papovaviridae, e.g. papillomavirus, polyomavirus, SV40, BK virus, JC virus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • C12N9/1252—DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/708—Specific hybridization probes for papilloma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
AU76018/87A 1986-07-23 1987-07-22 Expression products of human papilloma virus type 18, antibodies specific to these proteins, and diagnostic aids containing these antibodies or corresponding DNA Ceased AU597698B2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE3624786 1986-07-23
DE3624786 1986-07-23
DE3625257 1986-07-25
DE19863625257 DE3625257A1 (en) 1986-07-23 1986-07-25 EXPRESSION PRODUCTS OF THE HUMAN PAPILLOMVIRUS TYPE 16 AND 18, FOR THESE PROTEINS, SPECIFIC ANTIBODIES AND THESE ANTIBODIES OR. CORRESPONDING DNA-CONTAINING DIAGNOSTICS

Publications (2)

Publication Number Publication Date
AU7601887A AU7601887A (en) 1988-01-28
AU597698B2 true AU597698B2 (en) 1990-06-07

Family

ID=25845803

Family Applications (1)

Application Number Title Priority Date Filing Date
AU76018/87A Ceased AU597698B2 (en) 1986-07-23 1987-07-22 Expression products of human papilloma virus type 18, antibodies specific to these proteins, and diagnostic aids containing these antibodies or corresponding DNA

Country Status (3)

Country Link
EP (1) EP0256321A1 (en)
AU (1) AU597698B2 (en)
DE (1) DE3625257A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU650648B2 (en) * 1990-05-10 1994-06-30 Dade Behring Marburg Gmbh Seroreactive epitopes on proteins of human papillomavirus (HPV) 18

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU615159B2 (en) * 1986-03-21 1991-09-26 F. Hoffmann-La Roche Ltd Determined dna sequences derived from a papillomavirus genome, their uses for in vitro diagnostic purposes and the production of antigenic compositions
US4777239A (en) * 1986-07-10 1988-10-11 The Board Of Trustees Of The Leland Stanford Junior University Diagnostic peptides of human papilloma virus
DE3702116A1 (en) * 1987-01-24 1988-08-04 Behringwerke Ag CASSETTE VECTOR SYSTEM FOR EXPRESSING OPEN READING FRAME IN EUKARYOTIC CELLS
DE3722968A1 (en) * 1987-07-11 1989-01-19 Behringwerke Ag HUMAN PAPILLOMVIRUS TYPE 41, ITS DNA AND THE PROTEINS ENCODING IT
DE3722967A1 (en) * 1987-07-11 1989-01-19 Behringwerke Ag MONOCLONAL ANTIBODIES AGAINST E7 PROTEIN OF THE HUMAN PAPILLOMVIRUS TYPE 16, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE
DE3838269A1 (en) * 1988-11-11 1990-05-17 Behringwerke Ag IDENTIFYING HUMAN PAPILLOMAVIRUS DNA AND ITS EXPRESSION IN ZERVIX SLICES
FR2641081A1 (en) * 1988-12-23 1990-06-29 Medgenix Group
EP0662518B1 (en) * 1989-12-01 2001-11-07 VYSIS, Inc. Nucleic acid probes for detection of HPV transcripts
US5580970A (en) * 1989-12-01 1996-12-03 Amoco Corporation Detection of HPV transcripts
US5457189A (en) * 1989-12-04 1995-10-10 Isis Pharmaceuticals Antisense oligonucleotide inhibition of papillomavirus
SE9001705D0 (en) * 1990-05-11 1990-05-11 Medscand Ab SET FOR DIAGNOSTICS OF VIRUS BREAKING TUMORS BY IMMUNOASSAY
US5932412A (en) * 1990-05-11 1999-08-03 Euro-Diagnostica Ab Synthetic peptides in human papillomaviruses 1, 5, 6, 8, 11, 16, 18, 31, 33 and 56, useful in immunoassay for diagnostic purposes
EP0647140B1 (en) * 1992-06-25 2007-12-12 Georgetown University Papillomavirus vaccines
US5437951A (en) 1992-09-03 1995-08-01 The United States Of America As Represented By The Department Of Health And Human Services Self-assembling recombinant papillomavirus capsid proteins
DE69535018T2 (en) * 1994-05-16 2007-02-15 Merck & Co., Inc. PAPILLOMA VIRUS VACCINE
IL117459A (en) * 1995-03-22 2005-11-20 Merck & Co Inc Dna encoding human papillomavirus type 18
US6214541B1 (en) 1995-07-04 2001-04-10 Deutsches Krebsforschungszentrum Stiftung Des Offentlichen Rechts Process for detecting specific antibodies acting against HPV proteins
GB9621091D0 (en) 1996-10-09 1996-11-27 Fondation Pour Le Perfectionem Attenuated microorganisms strains and their uses
CA2441947C (en) 2001-03-23 2014-05-13 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Human papilloma virus immunoreactive peptides
US8968995B2 (en) 2008-11-12 2015-03-03 Oncohealth Corp. Detection, screening, and diagnosis of HPV-associated cancers
US20100003704A1 (en) 2008-06-13 2010-01-07 Shuling Cheng IN SITU detection of early stages and late stages HPV infection
JP2012526286A (en) 2009-05-07 2012-10-25 オンコヘルス コーポレーション Identification of advanced or ≧ CIN2 for detection, screening, and diagnosis of early and late stages of human papillomavirus (HPV) and HPV-related cancers
JP5819851B2 (en) 2010-01-08 2015-11-24 オンコヘルス コーポレーション Cell-based high-throughput HPV immunoassay for the treatment and screening of HPV-related cancers
CN109021097A (en) * 2017-06-08 2018-12-18 艾托金生物医药（苏州）有限公司 A kind of monoclonal antibody and its application identifying HPV18 and/or HPV45

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2524487B1 (en) * 1982-04-05 1985-11-22 Pasteur Institut DNA FRAGMENTS ENCODING POLYPEPTIDES CONTAINING AT LEAST ONE ANTIGENIC DETERMINANT OF PAPILLOMAVIRUS, IN PARTICULAR OF THE HPV 1A TYPE AND CORRESPONDING POLYPEPTIDES
EP0133123A1 (en) * 1983-07-25 1985-02-13 Mgi Pharma, Inc. Immunogens of papilloma viruses
CA1276575C (en) * 1984-11-30 1990-11-20 Sylvie Beaudenon Papillomavirus probes and process for the in vitro diagnostic of papillomavirus infections
DE3686304T2 (en) * 1985-04-04 1993-02-11 Univ Georgetown TYPE-SPECIFIC PAPILLOMAVIRUS DNA SEQUENCES AND PEPTIDES.
FR2586428B1 (en) * 1985-08-26 1988-11-25 Pasteur Institut POLYPEPTIDES AND ANTIBODIES, CHARACTERISTICS OF PAPILLOMAVIRUS AND THEIR APPLICATIONS TO IN VITRO DIAGNOSIS, PREVENTION AND / OR CONTROL OF PAPILLOMAVIRUS INFECTIONS

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU650648B2 (en) * 1990-05-10 1994-06-30 Dade Behring Marburg Gmbh Seroreactive epitopes on proteins of human papillomavirus (HPV) 18

Also Published As

Publication number Publication date
AU7601887A (en) 1988-01-28
EP0256321A1 (en) 1988-02-24
DE3625257A1 (en) 1988-02-04

Similar Documents

Publication Publication Date Title
AU597698B2 (en) Expression products of human papilloma virus type 18, antibodies specific to these proteins, and diagnostic aids containing these antibodies or corresponding DNA
AU7553587A (en) Diagnostic peptides of human papilloma virus
AU589537B2 (en) Medical micro pipette tips for difficult to reach places and related methods
NZ227177A (en) Vectors and dna compounds for the expression of human protein c
AU586758B2 (en) Purification of pichia-produced lipophilic proteins
NL194909B (en) Process for the preparation of polymerized hemoglobin and cell-free replacement for red blood cells on the basis thereof.
EP0263569A3 (en) 9-alpha-hydroxysteroids,process for their preparation,process for the preparation of the corresponding 9(11)-dehydro-derivatives and pharmaceutical preparations containing said steroids
AU7984287A (en) Proteins of aids envelope gene
HU900708D0 (en) Process for preparation of substituted 1,3-oxathiolanes and pharmaceutical preparations containing them
PT82575A (en) PROCESS FOR THE PREPARATION OF A CONJUGATE PRODUCT CONSISTING OF AN S.MUTANS ADHESIN OF A PROTEIN NATURE OF A COMPOSITION WITH IMMUNOGEN ACTIVITY AND AN S.MUTANS POLYSACCHARIDE AND USE THEREOF PARTICULARLY IN ANTI-CARIES VACCINES
AU7095887A (en) Human gamma interferon-specific receptor protein, antibody against said protein and said antibody and compositions containing said protein and antibody
AU7351591A (en) Seroreactive epitopes of human papillomavirus (HPV) 16 proteins
AU5637086A (en) Glycoprotein from membrane of human colon cells and antibodies
AU2622988A (en) Preparation and use of plants of improved biological value
AU2520692A (en) Vaccine containing polypeptides derived from the envelope gene of human immunodeficiency virus
DE3662970D1 (en) Improved blood-purifying membrane and process for preparation thereof
JPS6447383A (en) Hybridization probe of nucleic acid of human papilloma viruses and use thereof
AU8050687A (en) Nucleic acid probes for the detection of latent human cytomegalovirus in blood products
AU1676288A (en) Human immunodeficiency virus gag-encoded proteins
GB2189810B (en) Antibodies their preparation and use and products containing them
IL83670A0 (en) Dna coding for antigen protein of rinderpest virus and process for the preparation thereof
AU2713288A (en) Human-type serum obtained from fractions resulting from the fractionation of human blood or serum, process for its preparation and laboratory reaction containing said serum
AU1939788A (en) Preparation of novel protein sweeteners - monellin type
PT85229A (en) PROCESS FOR THE PREPARATION OF VARIANTS OF GLYCOSYLATED HUMAN ALPHA-ANTITRYSINE AND VIRAL VECTORS D: EXPRESSION OF L: ALPHA1-AT
AU3481389A (en) Antibodies to human papillomavirus latent proteins, diagnostic systems and methods