ATE178812T1 - Automatisches einfärbungsverfahren und - vorrichtung - Google Patents

Automatisches einfärbungsverfahren und - vorrichtung

Info

Publication number
ATE178812T1
ATE178812T1 AT94929964T AT94929964T ATE178812T1 AT E178812 T1 ATE178812 T1 AT E178812T1 AT 94929964 T AT94929964 T AT 94929964T AT 94929964 T AT94929964 T AT 94929964T AT E178812 T1 ATE178812 T1 AT E178812T1
Authority
AT
Austria
Prior art keywords
tip
arm
framework
reagent
wash
Prior art date
Application number
AT94929964T
Other languages
English (en)
Inventor
Ken Tseung
Wai Bun Wong
Christopher Michael Jones
Krishan L Kalra
Original Assignee
Biogenex Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogenex Lab filed Critical Biogenex Lab
Application granted granted Critical
Publication of ATE178812T1 publication Critical patent/ATE178812T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0275—Interchangeable or disposable dispensing tips
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31—Apparatus therefor
    • G01N1/312—Apparatus therefor for samples mounted on planar substrates
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/34—Microscope slides, e.g. mounting specimens on microscope slides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/2813—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
    • G01N2001/282—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on with mapping; Identification of areas; Spatial correlated pattern
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31—Apparatus therefor
    • G01N2001/317—Apparatus therefor spraying liquids onto surfaces
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027—General features of the devices
    • G01N2035/103—General features of the devices using disposable tips
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0099—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor comprising robots or similar manipulators
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1081—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane
    • G01N35/109—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane with two horizontal degrees of freedom

Landscapes

  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Optics & Photonics (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Cosmetics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT94929964T 1993-09-29 1994-09-29 Automatisches einfärbungsverfahren und - vorrichtung ATE178812T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/129,243 US5439649A (en) 1993-09-29 1993-09-29 Automated staining apparatus

Publications (1)

Publication Number Publication Date
ATE178812T1 true ATE178812T1 (de) 1999-04-15

Family

ID=22439074

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94929964T ATE178812T1 (de) 1993-09-29 1994-09-29 Automatisches einfärbungsverfahren und - vorrichtung

Country Status (6)

Country Link
US (1) US5439649A (de)
EP (1) EP0722363B1 (de)
JP (1) JP3540319B2 (de)
AT (1) ATE178812T1 (de)
DE (1) DE69417908T2 (de)
WO (1) WO1995010035A2 (de)

Families Citing this family (183)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6472217B1 (en) * 1990-03-02 2002-10-29 Ventana Medical Systems, Inc. Slide aqueous volume controlling apparatus
US5595707A (en) 1990-03-02 1997-01-21 Ventana Medical Systems, Inc. Automated biological reaction apparatus
US6180061B1 (en) * 1992-05-11 2001-01-30 Cytologix Corporation Moving platform slide stainer with heating elements
US20040191128A1 (en) * 1992-05-11 2004-09-30 Cytologix Corporation Slide stainer with heating
US5947167A (en) * 1992-05-11 1999-09-07 Cytologix Corporation Dispensing assembly with interchangeable cartridge pumps
US5605798A (en) 1993-01-07 1997-02-25 Sequenom, Inc. DNA diagnostic based on mass spectrometry
DE19539276C2 (de) * 1995-01-13 1998-03-19 Sarstedt Walter Geraete Vorrichtung zum Entnehmen und Ausstreichen von Flüssigkeiten
US6428955B1 (en) 1995-03-17 2002-08-06 Sequenom, Inc. DNA diagnostics based on mass spectrometry
JP3569779B2 (ja) * 1995-10-26 2004-09-29 アークレイ株式会社 廃棄トレイ付きチップカートリッジ
NO954650D0 (no) * 1995-11-17 1995-11-17 Torstein Ljungmann Fargemaskin for farging av vevspröver på objektglass
US6004512A (en) * 1995-12-08 1999-12-21 Mj Research Sample cartridge slide block
DE19605977C1 (de) * 1996-02-17 1997-06-05 Goldbecker Helmut Transportvorrichtung für Probenhalter mit medizinischen Präparaten
US6051378A (en) * 1996-03-04 2000-04-18 Genetrace Systems Inc. Methods of screening nucleic acids using mass spectrometry
EP0884577B1 (de) * 1996-09-18 2006-02-01 Kabushiki Kaisha Tiyoda Seisakusho Flüssigkeitsbehandlungsvorrichtung fur biologische proben
US5965363A (en) 1996-09-19 1999-10-12 Genetrace Systems Inc. Methods of preparing nucleic acids for mass spectrometric analysis
US6735531B2 (en) 1996-10-07 2004-05-11 Lab Vision Corporation Method and apparatus for automatic tissue staining
US5839091A (en) * 1996-10-07 1998-11-17 Lab Vision Corporation Method and apparatus for automatic tissue staining
US6024925A (en) 1997-01-23 2000-02-15 Sequenom, Inc. Systems and methods for preparing low volume analyte array elements
CA2268740C (en) 1996-11-06 2010-07-20 Sequenom, Inc. High density immobilization of nucleic acids
US7285422B1 (en) * 1997-01-23 2007-10-23 Sequenom, Inc. Systems and methods for preparing and analyzing low volume analyte array elements
EP0963443B1 (de) 1996-12-10 2006-03-08 Sequenom, Inc. Abspaltbare, nicht-flüchtige moleküle zur massenmarkierung
DE19652339A1 (de) * 1996-12-17 1998-06-18 Microm Laborgeraete Gmbh Vorrichtung zur Behandlung von Objekten
US6703247B1 (en) * 1996-12-23 2004-03-09 American Registry Of Pathology Apparatus and methods for efficient processing of biological samples on slides
US5958341A (en) * 1996-12-23 1999-09-28 American Registry Of Pathology Apparatus for efficient processing of tissue samples on slides
US5948359A (en) * 1997-03-21 1999-09-07 Biogenex Laboratories Automated staining apparatus
EP0878552A1 (de) 1997-05-13 1998-11-18 Erasmus Universiteit Rotterdam Molekularer Nachweis von chromosomalen Veränderungen
US6056923A (en) * 1997-06-25 2000-05-02 Clmp, Inc. Dual injector for chemiluminescence immunoanalyzing system
US6045759A (en) * 1997-08-11 2000-04-04 Ventana Medical Systems Fluid dispenser
US20020110494A1 (en) * 2000-01-14 2002-08-15 Ventana Medical Systems, Inc. Method and apparatus for modifying pressure within a fluid dispenser
US20050135972A1 (en) * 1997-08-11 2005-06-23 Ventana Medical Systems, Inc. Method and apparatus for modifying pressure within a fluid dispenser
US8137619B2 (en) * 1997-08-11 2012-03-20 Ventana Medical Systems, Inc. Memory management method and apparatus for automated biological reaction system
US6093574A (en) 1997-08-11 2000-07-25 Ventana Medical Systems Method and apparatus for rinsing a microscope slide
US6192945B1 (en) 1997-08-11 2001-02-27 Ventana Medical Systems, Inc. Fluid dispenser
NO306357B1 (no) * 1997-10-16 1999-10-25 Torstein Ljungmann Fargemaskin for preparering av vevspröver som er plassert pÕ objektglass
US6268131B1 (en) 1997-12-15 2001-07-31 Sequenom, Inc. Mass spectrometric methods for sequencing nucleic acids
US6444170B1 (en) * 1997-12-17 2002-09-03 Microm Laborgeräte GmbH Apparatus for the treatment for specimens
ATE489613T1 (de) 1998-02-27 2010-12-15 Ventana Med Syst Inc Automatisierter molekularer pathologieapparat mit unabhängigen objektträgerwärmern
US6183693B1 (en) * 1998-02-27 2001-02-06 Cytologix Corporation Random access slide stainer with independent slide heating regulation
US7396508B1 (en) 2000-07-12 2008-07-08 Ventana Medical Systems, Inc. Automated molecular pathology apparatus having independent slide heaters
US6582962B1 (en) 1998-02-27 2003-06-24 Ventana Medical Systems, Inc. Automated molecular pathology apparatus having independent slide heaters
US6096271A (en) * 1998-02-27 2000-08-01 Cytologix Corporation Random access slide stainer with liquid waste segregation
US6855559B1 (en) 1998-09-03 2005-02-15 Ventana Medical Systems, Inc. Removal of embedding media from biological samples and cell conditioning on automated staining instruments
US6022700A (en) * 1998-03-12 2000-02-08 Intelligent Imaging Innovations, Inc. High throughput biological sample preparation device and methods for use thereof
JP2002507738A (ja) * 1998-03-24 2002-03-12 バイオジェネックス ラボラトリーズ 自動着色装置
US6068754A (en) * 1998-04-27 2000-05-30 Koh; Francis H. Multi-tank gel developing apparatus and method
JP2002513587A (ja) 1998-05-04 2002-05-14 ダコ エー エス 染色体異常を検出するための方法およびプローブ
US6723564B2 (en) 1998-05-07 2004-04-20 Sequenom, Inc. IR MALDI mass spectrometry of nucleic acids using liquid matrices
EP1102994B1 (de) * 1998-08-04 2003-01-02 Dynex Technologies Inc. Automatisches immunoassay-gerät mit flexiblem hebearm
US6132685A (en) * 1998-08-10 2000-10-17 Caliper Technologies Corporation High throughput microfluidic systems and methods
US6855552B2 (en) 1998-09-03 2005-02-15 Ventana Medical Systems Automated immunohistochemical and in situ hybridization assay formulations
JP3782663B2 (ja) * 1998-09-03 2006-06-07 ベンタナ・メデイカル・システムズ・インコーポレーテツド 生物学的試料からの包埋媒体の除去および自動化された染色装置における細胞コンディショニング
US7410753B2 (en) * 1998-09-03 2008-08-12 Ventana Medical Systems, Inc. Removal of embedding media from biological samples and cell conditioning on automated staining instruments
US6562299B1 (en) * 1998-09-18 2003-05-13 Cytyc Corporation Method and apparatus for preparing cytological specimens
US6572824B1 (en) * 1998-09-18 2003-06-03 Cytyc Corporation Method and apparatus for preparing cytological specimens
US20030059347A1 (en) 1998-09-18 2003-03-27 Roy A. Ostgaard Sample vial for use in preparing cytological specimen
US20060216744A1 (en) * 1998-12-23 2006-09-28 American Registry Of Pathology Armed Forces Institute Of Pathology Apparatus and methods for efficient processing of biological samples on slides
CN1195585C (zh) * 1998-12-23 2005-04-06 病理学美国登记处 采用试剂处理生物样品的方法
US6544798B1 (en) * 1999-02-26 2003-04-08 Ventana Medical Systems, Inc. Removal of embedding media from biological samples and cell conditioning on automated staining instruments
US6103518A (en) * 1999-03-05 2000-08-15 Beecher Instruments Instrument for constructing tissue arrays
US6673318B1 (en) * 1999-05-31 2004-01-06 Bridgestone Corporation Pipette
EP1208378B9 (de) * 1999-07-08 2014-12-10 Lee H. Angros Vorrichtung und verfahren zum nachweis und zum anfärben von antigenen
US8298485B2 (en) * 1999-07-08 2012-10-30 Lee H. Angros In situ heat induced antigen recovery and staining apparatus and method
US7897106B2 (en) * 1999-07-08 2011-03-01 Lee Angros Situ heat induced antigen recovery and staining apparatus and method
US7951612B2 (en) * 1999-07-08 2011-05-31 Lee H. Angros In situ heat induced antigen recovery and staining apparatus and method
JP2001033463A (ja) * 1999-07-23 2001-02-09 Cosmo Tec:Kk 液体分注装置
EP1618948A3 (de) * 1999-08-09 2007-02-14 Thk Co. Ltd. Vorrichtung zur Herstellung von Mikroarrays
US6979425B1 (en) * 1999-10-04 2005-12-27 Robodesign International, Inc. High capacity microarray dispensing
US6358473B1 (en) * 1999-10-05 2002-03-19 Albert Coello Microscope slide heater
US6746851B1 (en) * 2000-01-14 2004-06-08 Lab Vision Corporation Method for automated staining of specimen slides
US7160511B2 (en) * 2000-02-18 2007-01-09 Olympus Corporation Liquid pipetting apparatus and micro array manufacturing apparatus
EP1284823A1 (de) * 2000-03-16 2003-02-26 Biogenex Laboratories Automatische probenverarbeitungsvorrichtung mit fluiddetektion
DE60137722D1 (de) 2000-06-13 2009-04-02 Univ Boston Verwendung von mass-matched nukleotide in der analyse von oligonukleotidmischungen sowie in der hoch-multiplexen nukleinsäuresequenzierung
JP4015946B2 (ja) 2000-10-30 2007-11-28 シークエノム・インコーポレーテツド 基板上にサブマイクロリットルの体積を供給する方法及び装置
DE20018628U1 (de) * 2000-11-01 2002-03-14 EVOTEC BioSystems AG, 22525 Hamburg Probenabgabevorrichtung
GB0117706D0 (en) * 2001-02-16 2001-09-12 Aventis Pharm Prod Inc Automated semi-solid matrix assay and liquid handler apparatus for the same
CA2441439A1 (en) * 2001-03-16 2002-10-17 Memorec Biotec Gmbh Accommodating device for specimen slides
US7297311B2 (en) * 2001-06-29 2007-11-20 Sysmex Corporation Automatic smear preparing apparatus and automatic sample analysis system having the same
ITFI20010159A1 (it) * 2001-08-24 2003-02-24 Tecnorama Srl Macchina ed impianto per la tintura di materiali tessili
US7425306B1 (en) 2001-09-11 2008-09-16 Ventana Medical Systems, Inc. Slide heater
US20030087454A1 (en) * 2001-10-26 2003-05-08 Schultz Gary A Method and device for chemical analysis
WO2003042788A2 (en) 2001-11-13 2003-05-22 Chromavision Medical Systems, Inc. A system for tracking biological samples
US20040033163A1 (en) * 2001-11-26 2004-02-19 Lab Vision Corporation Automated tissue staining system and reagent container
US6998270B2 (en) 2001-11-26 2006-02-14 Lab Vision Corporation Automated tissue staining system and reagent container
US6889468B2 (en) * 2001-12-28 2005-05-10 3M Innovative Properties Company Modular systems and methods for using sample processing devices
US7754155B2 (en) * 2002-03-15 2010-07-13 Ross Amelia A Devices and methods for isolating target cells
US20030189850A1 (en) * 2002-04-09 2003-10-09 Toyo Boseki Kabushiki Kaisha Cell array system
US7468161B2 (en) 2002-04-15 2008-12-23 Ventana Medical Systems, Inc. Automated high volume slide processing system
US11249095B2 (en) 2002-04-15 2022-02-15 Ventana Medical Systems, Inc. Automated high volume slide processing system
CA2482441C (en) 2002-04-15 2010-06-22 Ventana Medical Systems, Inc. Automated high volume slide staining system
WO2003091710A1 (en) * 2002-04-26 2003-11-06 Ventana Medical Systems, Inc. Automated molecular pathology apparatus having fixed slide platforms
US7718072B2 (en) 2002-04-26 2010-05-18 Abbott Laboratories Structure and method for handling magnetic particles in biological assays
DE10223412B4 (de) * 2002-05-25 2011-11-10 Leica Biosystems Nussloch Gmbh Tableau zum Aufnehmen von Kassetten und/oder von Objektträgern für histologische oder zytologische Präparate
AU2003901871A0 (en) * 2003-03-31 2003-05-08 Vision Biosystems Limited A method and apparatus for fluid dispensation, preparation and dilation
WO2004001390A1 (en) * 2002-06-20 2003-12-31 Vision Biosystems Limited Biological reaction apparatus with draining mechanism
WO2004008106A2 (en) * 2002-07-16 2004-01-22 Ventana Medical Systems, Inc. Tray for automated histochemical processing
DE10247731B4 (de) * 2002-10-12 2007-04-12 Eppendorf Ag Greifwerkzeug, Dosierwerkzeug und Werkzeughalter für einen Laborautomaten
CA2503797A1 (en) * 2002-11-08 2004-05-27 Irm, Llc Systems and methods of sorting samples
US7648678B2 (en) 2002-12-20 2010-01-19 Dako Denmark A/S Method and system for pretreatment of tissue slides
US7584019B2 (en) * 2003-12-15 2009-09-01 Dako Denmark A/S Systems and methods for the automated pre-treatment and processing of biological samples
US7850912B2 (en) * 2003-05-14 2010-12-14 Dako Denmark A/S Method and apparatus for automated pre-treatment and processing of biological samples
US7875245B2 (en) * 2003-05-14 2011-01-25 Dako Denmark A/S Method and apparatus for automated pre-treatment and processing of biological samples
DE10321753B4 (de) * 2003-05-15 2010-10-28 Eppendorf Ag Vorrichtung zum automatischen Bearbeiten von Flüssigkeiten
US20080235055A1 (en) * 2003-07-17 2008-09-25 Scott Mattingly Laboratory instrumentation information management and control network
US7860727B2 (en) 2003-07-17 2010-12-28 Ventana Medical Systems, Inc. Laboratory instrumentation information management and control network
US8719053B2 (en) 2003-07-17 2014-05-06 Ventana Medical Systems, Inc. Laboratory instrumentation information management and control network
US9518899B2 (en) 2003-08-11 2016-12-13 Sakura Finetek U.S.A., Inc. Automated reagent dispensing system and method of operation
US7767152B2 (en) 2003-08-11 2010-08-03 Sakura Finetek U.S.A., Inc. Reagent container and slide reaction retaining tray, and method of operation
US7501283B2 (en) * 2003-08-11 2009-03-10 Sakura Finetek U.S.A., Inc. Fluid dispensing apparatus
US7744817B2 (en) 2003-08-11 2010-06-29 Sakura Finetek U.S.A., Inc. Manifold assembly
EP2486980B1 (de) * 2003-09-09 2014-12-03 BioGenex Laboratories Probenverarbeitungssystem
JP2007526479A (ja) 2004-03-02 2007-09-13 ダコ デンマーク アクティーゼルスカブ 生物学的染色装置のための試薬送達システム、分配デバイスおよび容器
US20050274395A1 (en) * 2004-06-14 2005-12-15 Applera Corporation Microarray wash tray
CA2512353A1 (en) * 2004-07-16 2006-01-16 Stemcell Technologies Inc. Automated pipette machine
US7867443B2 (en) * 2004-07-23 2011-01-11 Dako Denmark A/S Method and apparatus for automated pre-treatment and processing of biological samples
US7475964B2 (en) 2004-08-06 2009-01-13 Hewlett-Packard Development Company, L.P. Electrical contact encapsulation
US8986614B2 (en) * 2010-02-23 2015-03-24 Rheonix, Inc. Self-contained biological assay apparatus, methods, and applications
CA2591868A1 (en) * 2004-12-30 2006-07-13 Ventana Medical Systems, Inc. Low temperature deparaffinization
GB0501590D0 (en) * 2005-01-25 2005-03-02 Ceres Power Ltd Processing of enhanced performance LSCF fuel cell cathode microstructure and a fuel cell cathode
US20060180489A1 (en) * 2005-02-02 2006-08-17 Cytyc Corporation Slide tray
JP2006288308A (ja) * 2005-04-12 2006-10-26 Kajikkusu Trading:Kk シール剥離装置
US7678337B2 (en) * 2005-04-26 2010-03-16 Abbott Laboratories Inc. Assembly for carrying and holding slides
WO2006127852A2 (en) 2005-05-24 2006-11-30 Angros Lee H In situ heat induced antigen recovery and staining apparatus and method
AU2006312250B2 (en) * 2005-06-28 2011-07-07 The Board Of Regents Of The University Of Oklahoma Methods for growing and harvesting carbon nanotubes
US7754474B2 (en) 2005-07-05 2010-07-13 3M Innovative Properties Company Sample processing device compression systems and methods
US7323660B2 (en) 2005-07-05 2008-01-29 3M Innovative Properties Company Modular sample processing apparatus kits and modules
US7763210B2 (en) 2005-07-05 2010-07-27 3M Innovative Properties Company Compliant microfluidic sample processing disks
US8789756B2 (en) * 2006-02-25 2014-07-29 Roche Diagnostics Operations, Inc. Test element coding apparatuses, systems and methods
US9551635B2 (en) 2006-03-09 2017-01-24 Biogenex Laboratories Inc. Sample processing system
FR2898285B1 (fr) * 2006-03-13 2008-04-18 Biomerieux Sa Dispositif, utilisation et procede de prelevement d'un liquide
US8241593B2 (en) * 2006-05-04 2012-08-14 The Bode Technology Group, Inc. Specimen tray
US8459509B2 (en) 2006-05-25 2013-06-11 Sakura Finetek U.S.A., Inc. Fluid dispensing apparatus
US7449153B2 (en) * 2006-07-21 2008-11-11 Cytyc Corporation Tray for slide processing
US20080081368A1 (en) * 2006-10-03 2008-04-03 Anne Marie Bailey Method and apparatus that increases efficiency and reproducibility in immunohistochemistry and immunocytochemistry
EP2156370B1 (de) 2007-05-14 2011-10-12 Historx, Inc. Abteilungsauftrennung durch pixelcharakterisierung unter verwendung von bilddatenclusterung
EP2162728B1 (de) * 2007-06-15 2016-07-27 Novartis AG Mikroskopisches system und verfahren zur erfassung von standardisierten daten
CA2604317C (en) 2007-08-06 2017-02-28 Historx, Inc. Methods and system for validating sample images for quantitative immunoassays
CA2596204C (en) 2007-08-07 2019-02-26 Historx, Inc. Method and system for determining an optimal dilution of a reagent
WO2009029810A1 (en) * 2007-08-31 2009-03-05 Historx, Inc. Automatic exposure time selection for imaging tissue
WO2009039122A2 (en) 2007-09-17 2009-03-26 Sequenom, Inc. Integrated robotic sample transfer device
JP4975599B2 (ja) * 2007-12-17 2012-07-11 シスメックス株式会社 標本作製装置および標本作製方法
AU2009218872B2 (en) 2008-02-29 2015-01-15 Agilent Technologies, Inc. Systems and methods for tracking and providing workflow information
EP2263069B1 (de) * 2008-04-10 2019-06-05 Denator Aktiebolag Vorrichtung zur lagerung einer biologischen probe und zur präparation der biologischen probe
DE102008018982A1 (de) * 2008-04-14 2009-11-05 Merz, Hartmut, Prof. Dr. med. Automatische Vorrichtung zur Durchführung von Nachweisreaktionen und Verfahren zur Dosierung von Reagenzien auf Objektträgern
WO2009152569A1 (en) * 2008-06-16 2009-12-23 Leica Biosystems Melbourne Pty Ltd Improvements in staining instruments and methods
GB2477648B (en) 2008-08-29 2013-02-20 Lee H Angros In situ heat induced antigen recovery and staining apparatus and method
WO2010033508A1 (en) 2008-09-16 2010-03-25 Historx, Inc. Reproducible quantification of biomarker expression
KR101548407B1 (ko) 2008-11-12 2015-08-28 벤타나 메디컬 시스템즈, 인코포레이티드 시료 운반 슬라이드를 가열하기 위한 방법 및 장치
WO2010077975A1 (en) * 2008-12-17 2010-07-08 Ventana Medical Systems, Inc. Apparatus for sealing slide bottom
USD638951S1 (en) 2009-11-13 2011-05-31 3M Innovative Properties Company Sample processing disk cover
US8834792B2 (en) 2009-11-13 2014-09-16 3M Innovative Properties Company Systems for processing sample processing devices
USD638550S1 (en) 2009-11-13 2011-05-24 3M Innovative Properties Company Sample processing disk cover
USD667561S1 (en) 2009-11-13 2012-09-18 3M Innovative Properties Company Sample processing disk cover
EP2539719B1 (de) * 2010-02-23 2019-12-25 Rheonix, Inc. Selbsthaltende vorrichtung für biologische assays sowie verfahren dafür und anwendungen davon
US9102979B2 (en) 2010-02-23 2015-08-11 Rheonix, Inc. Self-contained biological assay apparatus, methods, and applications
WO2011139978A1 (en) * 2010-05-04 2011-11-10 Ventana Medical Systems, Inc. Moving meniscus rinsing and mixing in cell staining
US8900527B2 (en) * 2010-06-29 2014-12-02 Roche Molecular Systems Inc. Pipetting device with independently movable pipette units
WO2012048154A1 (en) 2010-10-06 2012-04-12 Biocare Medical, Llc Methods and systems for efficient processing of biological samples
DE102010061611B3 (de) * 2010-12-29 2012-02-16 Leica Biosystems Nussloch Gmbh Identifizierung von Objektträgern
US8752732B2 (en) 2011-02-01 2014-06-17 Sakura Finetek U.S.A., Inc. Fluid dispensing system
US9945763B1 (en) 2011-02-18 2018-04-17 Biocare Medical, Llc Methods and systems for immunohistochemistry heat retrieval of biological samples
ES2755078T3 (es) 2011-05-18 2020-04-21 Diasorin S P A Sistemas y métodos para medición volumétrica en un dispositivo de procesamiento de muestra
EP2709762B1 (de) 2011-05-18 2021-03-31 DiaSorin S.p.A. Vorrichtung und verfahren zum erkennen eines vorbestimmten volumens eines materials in einer probenverarbeitungsvorrichtung
CN103501908B (zh) 2011-05-18 2016-03-16 3M创新有限公司 用于样品处理装置上阀调的系统和方法
US8580568B2 (en) 2011-09-21 2013-11-12 Sakura Finetek U.S.A., Inc. Traceability for automated staining system
US8932543B2 (en) 2011-09-21 2015-01-13 Sakura Finetek U.S.A., Inc. Automated staining system and reaction chamber
US9269138B2 (en) * 2012-07-13 2016-02-23 Roche Diagnostics Hematology, Inc. Controlled dispensing of samples onto substrates
HU230739B1 (hu) 2013-02-28 2018-01-29 3Dhistech Kft. Berendezés és eljárás tárgylemezek automatikus festésére, fedésére, digitalizálására integrált tárgylemez festő-fedő-digitalizáló automata berendezés segítségével
US20160266162A1 (en) * 2013-11-06 2016-09-15 Degree Of Freedom Scientific Machine Co., Ltd. Fully-automatic pipetting instrument and use thereof
JP6232138B2 (ja) 2013-12-13 2017-11-15 ベンタナ メディカル システムズ， インコーポレイテッド 生物学的試料の組織学的処理のための染色試薬および他の液体ならびに関連技術
CN105829862B (zh) 2013-12-13 2021-11-09 文塔纳医疗系统公司 热处理显微镜载玻片的自动化处理系统及方法
CA2932803C (en) 2013-12-13 2020-09-08 Ventana Medical Systems, Inc. Thermal management in the context of automated histological processing of biological specimens and associated technology
EP3080579B1 (de) 2013-12-13 2022-07-27 Ventana Medical Systems, Inc. Automatisiertes trägerbearbeitungsgerät
EP3160648B1 (de) * 2014-06-30 2024-04-03 Ventana Medical Systems, Inc. Probenverarbeitungssysteme, pipettenanordnungen und verfahren zur zubereitung von reagenzien
CN104502171B (zh) * 2014-11-27 2017-05-31 嘉兴凯实生物科技有限公司 一种自动荧光染片机
CA2980595C (en) 2015-04-09 2020-09-22 Gen-Probe Incorporated Sample testing systems and methods with automated cleaning
CN105259008A (zh) * 2015-10-30 2016-01-20 广州鸿琪光学仪器科技有限公司 柱塞泵加样染色组件及染色机
IT201600078037A1 (it) 2016-07-26 2018-01-26 I M A Industria Macch Automatiche S P A In Sigla Ima S P A Macchina per il riempimento di flaconi, cartucce, siringhe e simili
US20210108996A1 (en) * 2017-03-31 2021-04-15 X-Zell Inc. Automatic slide staining and cooling systems
US20220023853A1 (en) * 2018-12-20 2022-01-27 Tecan Trading Ag Method of treating a sample
CN111551756B (zh) * 2020-04-01 2023-07-18 郑州中普医疗器械有限公司 一种全自动制片染色扫描系统
CN112747991B (zh) * 2020-12-23 2023-04-07 山东骏腾医疗科技有限公司 一种组织切片全自动滴染装置
CN114152496A (zh) * 2021-12-31 2022-03-08 河南赛诺特生物技术有限公司 一种自动免疫组化染色机
CN114308172A (zh) * 2022-03-03 2022-04-12 迈德(山东)科技股份有限公司 一种全自动试剂分装装置及分装方法

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3853092A (en) * 1973-10-25 1974-12-10 Corning Glass Works Apparatus for nutating and staining a microscope slide
US4004550A (en) * 1973-11-29 1977-01-25 White Ronald D Apparatus for preparing microscope slides
US4042999A (en) * 1975-01-17 1977-08-23 Demetrios Triantafyllou Miniaturized vacuum cleaner device
DE2515869C3 (de) * 1975-04-11 1979-11-08 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren und Vorrichtung zur Herstellung von vorbeschichteten Objektträgern
US4043292A (en) * 1975-07-21 1977-08-23 Corning Glass Works Microscope slide staining apparatus having temperature control
US4013038A (en) * 1975-07-21 1977-03-22 Corning Glass Works Apparatus for controlling the temperature of a liquid body
US4030341A (en) * 1975-07-24 1977-06-21 Corning Glass Works Fluid application device
US4034700A (en) * 1976-05-25 1977-07-12 Honeywell Inc. Slide preparation station
CA1106711A (en) * 1976-10-08 1981-08-11 Leighton C. Johnson System for evenly applying liquid to a surface
US4200056A (en) * 1977-01-21 1980-04-29 Miles Laboratories, Inc. Segmented platen for applying liquids to a flat surface
JPS55162049A (en) * 1979-06-05 1980-12-17 Olympus Optical Co Ltd Specimen coating device
US4305722A (en) * 1980-06-13 1981-12-15 Coulter Electronics, Inc. Wetting cycle for spun blood smears
DE3625683A1 (de) * 1986-07-30 1988-02-11 Hoechst Ag Vorrichtung zum benetzen von teststreifen
GB8722902D0 (en) * 1987-09-30 1987-11-04 Shandon Southern Prod Tissue &c processing
US4950455A (en) * 1987-12-22 1990-08-21 Board Of Regents, University Of Texas System Apparatus for quantifying components in liquid samples
DE3805808A1 (de) * 1988-02-24 1989-09-07 Europ Lab Molekularbiolog Automatische arbeitsstation fuer mikrobiologische arbeiten
US5009185A (en) * 1989-05-09 1991-04-23 Wescor, Inc. Apparatus for applying a controlled amount of reagent to a microscope slide or the like
US5180606A (en) * 1989-05-09 1993-01-19 Wescor, Inc. Apparatus for applying a controlled amount of reagent to a microscope slide or the like
GB8919145D0 (en) * 1989-08-23 1989-10-04 Royal Postgrad Med School Apparatus for the in situ hybridisation of slide-mounted cell samples
US5225325A (en) * 1990-03-02 1993-07-06 Ventana Medical Systems, Inc. Immunohistochemical staining method and reagents therefor
JPH06504115A (ja) * 1990-07-18 1994-05-12 ヴィジョン　インストゥルメンツ　リミテッド 免疫組織化学のための自動的組織染色
US5355439A (en) * 1991-08-05 1994-10-11 Bio Tek Instruments Method and apparatus for automated tissue assay

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DE69417908D1 (de) 1999-05-20
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US5439649A (en) 1995-08-08
JPH09503304A (ja) 1997-03-31
JP3540319B2 (ja) 2004-07-07
EP0722363B1 (de) 1999-04-14
WO1995010035A2 (en) 1995-04-13
WO1995010035A3 (en) 1995-06-01
EP0722363A4 (de) 1996-12-11

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