ATE171479T1 - Verfahren zur herstellung von neuen biopolymeren - Google Patents

Verfahren zur herstellung von neuen biopolymeren

Info

Publication number
ATE171479T1
ATE171479T1 AT92908537T AT92908537T ATE171479T1 AT E171479 T1 ATE171479 T1 AT E171479T1 AT 92908537 T AT92908537 T AT 92908537T AT 92908537 T AT92908537 T AT 92908537T AT E171479 T1 ATE171479 T1 AT E171479T1
Authority
AT
Austria
Prior art keywords
nucleic acid
acid sequences
mixtures
new biopolymers
properties
Prior art date
Application number
AT92908537T
Other languages
German (de)
English (en)
Inventor
Karsten Henco
Manfred Eigen
Original Assignee
Evotec Biosystems Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6429722&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE171479(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Evotec Biosystems Gmbh filed Critical Evotec Biosystems Gmbh
Application granted granted Critical
Publication of ATE171479T1 publication Critical patent/ATE171479T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1058Directional evolution of libraries, e.g. evolution of libraries is achieved by mutagenesis and screening or selection of mixed population of organisms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1079Screening libraries by altering the phenotype or phenotypic trait of the host

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Ecology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
AT92908537T 1991-04-16 1992-04-14 Verfahren zur herstellung von neuen biopolymeren ATE171479T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4112440A DE4112440C1 (enExample) 1991-04-16 1991-04-16

Publications (1)

Publication Number Publication Date
ATE171479T1 true ATE171479T1 (de) 1998-10-15

Family

ID=6429722

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92908537T ATE171479T1 (de) 1991-04-16 1992-04-14 Verfahren zur herstellung von neuen biopolymeren

Country Status (5)

Country Link
EP (1) EP0583265B1 (enExample)
JP (1) JP3504658B2 (enExample)
AT (1) ATE171479T1 (enExample)
DE (2) DE4112440C1 (enExample)
WO (1) WO1992018645A1 (enExample)

Families Citing this family (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4237381C1 (de) * 1992-11-05 1994-04-28 Diagen Inst Molekularbio Trägermaterial zur simultanen Bindung genotypischer und phänotypischer Substanzen
US5849545A (en) * 1992-05-11 1998-12-15 Evotec Biosystems Gmbh Substrate material for simultaneously binding genotypic and phenotypic substances
DE4343591A1 (de) * 1993-12-21 1995-06-22 Evotec Biosystems Gmbh Verfahren zum evolutiven Design und Synthese funktionaler Polymere auf der Basis von Formenelementen und Formencodes
US5605793A (en) * 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
US6335160B1 (en) 1995-02-17 2002-01-01 Maxygen, Inc. Methods and compositions for polypeptide engineering
US6309883B1 (en) 1994-02-17 2001-10-30 Maxygen, Inc. Methods and compositions for cellular and metabolic engineering
US6117679A (en) 1994-02-17 2000-09-12 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
US5837458A (en) 1994-02-17 1998-11-17 Maxygen, Inc. Methods and compositions for cellular and metabolic engineering
US6995017B1 (en) 1994-02-17 2006-02-07 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
US6165793A (en) * 1996-03-25 2000-12-26 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
EP0714980A1 (en) * 1994-12-02 1996-06-05 Institut Pasteur Hypermutagenesis
WO1996017056A1 (en) * 1994-12-02 1996-06-06 Institut Pasteur Hypermutagenesis
US6936289B2 (en) 1995-06-07 2005-08-30 Danisco A/S Method of improving the properties of a flour dough, a flour dough improving composition and improved food products
JPH1066577A (ja) * 1996-08-07 1998-03-10 Novo Nordisk As 核酸プールおよびその製造方法
EP1712623B1 (en) 1997-01-21 2011-10-19 The General Hospital Corporation Selection of proteins using RNA-protein fusions
US8207093B2 (en) 1997-01-21 2012-06-26 The General Hospital Corporation Selection of proteins using RNA-protein fusions
US6261804B1 (en) 1997-01-21 2001-07-17 The General Hospital Corporation Selection of proteins using RNA-protein fusions
US6153410A (en) * 1997-03-25 2000-11-28 California Institute Of Technology Recombination of polynucleotide sequences using random or defined primers
DE69825263T3 (de) 1997-04-09 2009-03-12 Danisco A/S Lipase und verwendung davon zur verbesserung von teigen und backwaren
US6927025B1 (en) 1997-09-03 2005-08-09 Biovation Limited Methods for protein screening
EP1003853B1 (en) * 1997-09-03 2005-11-30 Biovation Limited Methods for protein screening
AU754377B2 (en) * 1997-09-03 2002-11-14 Merck Patent Gesellschaft Mit Beschrankter Haftung Methods for protein screening
IL136574A0 (en) 1997-12-08 2001-06-14 California Inst Of Techn A method for forming a polynucleotide of desired properties
US7153655B2 (en) 1998-06-16 2006-12-26 Alligator Bioscience Ab Method for in vitro molecular evolution of protein function involving the use of exonuclease enzyme and two populations of parent polynucleotide sequence
IL140125A0 (en) 1998-06-17 2002-02-10 Maxygen Inc Method for producing polynucleotides with desired properties
US6846655B1 (en) 1998-06-29 2005-01-25 Phylos, Inc. Methods for generating highly diverse libraries
ATE231186T1 (de) 1998-07-21 2003-02-15 Danisco Lebensmittel
ES2329205T3 (es) 1998-08-17 2009-11-23 Bristol-Myers Squibb Company Identificacion de interacciones de compuestos-proteinas usando bibliotecas de moleculas de fusion de proteinas-acidos nucleicos.
DE19953854C2 (de) 1999-11-09 2002-01-17 Max Planck Gesellschaft Verfahren zur Herstellung von Biopolymeren mit veränderten Eigenschaften
EP1250463B1 (en) 2000-01-24 2006-04-05 Compound Therapeutics, Inc. Sensitive, multiplexed diagnostic assays for protein analysis
US7022479B2 (en) 2000-01-24 2006-04-04 Compound Therapeutics, Inc. Sensitive, multiplexed diagnostic assays for protein analysis
US6958213B2 (en) 2000-12-12 2005-10-25 Alligator Bioscience Ab Method for in vitro molecular evolution of protein function
US20020086292A1 (en) 2000-12-22 2002-07-04 Shigeaki Harayama Synthesis of hybrid polynucleotide molecules using single-stranded polynucleotide molecules
US7838219B2 (en) 2001-02-02 2010-11-23 Novici Biotech Llc Method of increasing complementarity in a heteroduplex
US7582423B2 (en) 2001-02-02 2009-09-01 Novici Biotech Llc Population of polynucleotide sequence variants
ATE447019T1 (de) 2001-02-02 2009-11-15 Large Scale Biology Corp Methode zur erhöhung der komplementarität in einem heteroduplex-polynucleotid
DE60220155T2 (de) 2001-05-18 2008-02-07 Danisco A/S Verfahren zur herstellung von teig mit einem enzym
EP1840211A1 (en) 2001-10-31 2007-10-03 Danisco A/S Pyranosone dehydratase from phanerochaete chrysosporium
US7078211B2 (en) 2002-02-01 2006-07-18 Large Scale Biology Corporation Nucleic acid molecules encoding endonucleases and methods of use thereof
ES2285118T5 (es) 2002-05-17 2012-09-21 Alligator Bioscience Ab Un método para el desarrollo molecular in vitro de una función proteica.
JP2005539093A (ja) * 2002-07-17 2005-12-22 ユニリーバー・ナームローゼ・ベンノートシヤープ 分枝状アルコールのカルボキシアルキレート及び/またはそのアルコキシレートを含有するスキンケア用化粧組成物
US7955814B2 (en) 2003-01-17 2011-06-07 Danisco A/S Method
MXPA05007654A (es) 2003-01-17 2005-09-30 Danisco Metodo.
US20050196766A1 (en) 2003-12-24 2005-09-08 Soe Jorn B. Proteins
ES2525711T3 (es) 2003-01-17 2014-12-29 Dupont Nutrition Biosciences Aps Método para producir un éster de proteína o un éster de subunidad de proteína
EP1633865B1 (en) 2003-06-18 2011-09-28 Bayer Pharma Aktiengesellschaft New biological entities and the use thereof
US7718408B2 (en) 2003-12-24 2010-05-18 Danisco A/S Method
GB0716126D0 (en) 2007-08-17 2007-09-26 Danisco Process
EP2119771B1 (en) 2003-12-24 2018-08-22 DuPont Nutrition Biosciences ApS Proteins
GB0405637D0 (en) 2004-03-12 2004-04-21 Danisco Protein
CA2571694C (en) 2004-07-16 2014-09-02 Danisco A/S Enzymatic oil-degumming method
GB0421598D0 (en) 2004-09-29 2004-10-27 Cambridge Advanced Tech Modification of plant development and morphology
GB0422052D0 (en) 2004-10-04 2004-11-03 Dansico As Enzymes
GB0423139D0 (en) 2004-10-18 2004-11-17 Danisco Enzymes
US8846366B2 (en) 2006-12-14 2014-09-30 Dsm Ip Assets Bv R-hydroxynitrile lyase (R-HNL) random variants and their use for preparing optically pure, sterically hindered cyanohydrins
CA2673954C (en) 2007-01-25 2015-09-15 Danisco A/S Production of a lipid acyltransferase from transformed bacillus licheniformis cells
US20080220498A1 (en) 2007-03-06 2008-09-11 Cervin Marguerite A Variant Buttiauxella sp. phytases having altered properties
US8143046B2 (en) 2007-02-07 2012-03-27 Danisco Us Inc., Genencor Division Variant Buttiauxella sp. phytases having altered properties
EP2147104B1 (en) 2007-05-21 2015-09-09 Danisco US Inc. Use of an aspartic protease (nsp24) signal sequence for heterologous protein expression
EP3118309B1 (en) 2008-04-18 2020-09-16 Danisco US Inc. Buttiauxella sp. phytase variants
EP2279248B1 (en) 2008-04-30 2015-04-01 DuPont Nutrition Biosciences ApS Proteins
GB0908770D0 (en) 2009-04-24 2009-07-01 Danisco Method
EP2432876A1 (en) 2009-05-19 2012-03-28 Danisco A/S Use
AR077042A1 (es) 2009-06-12 2011-07-27 Danisco Metodo para tratar una composicion que contiene pirofiofitina
GB0920089D0 (en) 2009-11-17 2009-12-30 Danisco Method
BR112012017292B1 (pt) 2010-01-13 2021-05-18 Basf Se variante de mananase, molécula de ácido nucleico, método para a preparação da mananase modificada, composição e uso da mananase modificada
MX2012010399A (es) 2010-03-12 2012-10-05 Dupont Nutrition Biosci Aps Proceso.
WO2011114251A1 (en) 2010-03-18 2011-09-22 Danisco A/S Foodstuff
US20130085287A1 (en) 2010-06-17 2013-04-04 Dupont Nutrition Biosciences Aps Process
GB201011513D0 (en) 2010-07-08 2010-08-25 Danisco Method
AR085251A1 (es) 2011-02-23 2013-09-18 Danisco Proceso para tratar aceite vegetal
CA3004088A1 (en) 2011-02-23 2012-08-30 Dupont Nutrition Biosciences Aps Enzymatic treatment of plant oil
AR085253A1 (es) 2011-02-23 2013-09-18 Danisco Metodo para producir una clorofilasa
US20140031272A1 (en) 2011-04-08 2014-01-30 Danisco Us Inc. Compositions
PL2691530T3 (pl) 2011-06-10 2019-02-28 Oregon Health & Science University Glikoproteiny i rekombinowane wektory CMV
WO2013104660A1 (en) 2012-01-13 2013-07-18 Dupont Nutrition Biosciences Aps Process for treating a plant oil comprising hydrolysing chlorophyll or a chlorophyll derivative and involving partial caustic neutralisation
WO2013104659A2 (en) 2012-01-13 2013-07-18 Dupont Nutrition Biosciences Aps Process
WO2013160374A1 (en) 2012-04-27 2013-10-31 Dupont Nutrition Biosciences Aps Process for refining crude plant oil involving enzymatic hydrolysis and gum recycling
WO2013160372A1 (en) 2012-04-27 2013-10-31 Dupont Nutrition Biosciences Aps Process for treating plant oil involving addition of serial doses of chlorophyll or chlorophyll derivative degrading enzyme
WO2014063097A1 (en) 2012-10-19 2014-04-24 Danisco Us Inc. Stabilization of biomimetic membranes
DK3083936T3 (en) 2013-12-19 2018-10-22 Danisco Us Inc USE OF HYDROPHOBINES TO INCREASE GAS TRANSFER IN AEROBE FERMENTATION PROCESSES
WO2015150372A1 (en) 2014-04-01 2015-10-08 Dupont Nutrition Biosciences Aps Method for increasing crude palm oil yields
US20170306360A1 (en) 2014-10-24 2017-10-26 Danisco Us Inc. Method for producing alcohol by use of a tripeptidyl peptidase
AU2015334890B2 (en) 2014-10-24 2021-12-23 Dupont Nutrition Biosciences Aps Proline tolerant tripeptidyl peptidases and uses thereof
BR112017028035A2 (pt) 2015-06-26 2018-08-28 Dupont Nutrition Biosci Aps aminopeptidases para hidrolisados de proteína
CN108779483A (zh) 2016-02-25 2018-11-09 杜邦营养生物科学有限公司 使用烟曲霉三肽基肽酶生产蛋白水解产物的方法
DE102023001827A1 (de) 2023-04-19 2024-10-24 Horst Wochnowski Verfahren und dazugehörige Vorrichtung zum Züchten von in Gewässern Mikroplastik zersetzenden und abbauenden Mikroorganismenstämme durch einen künstlich herbeigeführten und beschleunigten Evolutions- und Selektionsprozess

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0285123A3 (en) * 1987-04-03 1989-02-01 Stabra AG A method for complete mutagenesis of nucleic acids
AU638762B2 (en) * 1989-10-05 1993-07-08 Optein Inc Cell-free synthesis and isolation of novel genes and polypeptides
AU8498091A (en) * 1990-08-02 1992-03-02 Regents Of The University Of Colorado, The Systematic polypeptide evolution by reverse translation

Also Published As

Publication number Publication date
EP0583265B1 (de) 1998-09-23
DE59209506D1 (de) 1998-10-29
WO1992018645A1 (de) 1992-10-29
DE4112440C1 (enExample) 1992-10-22
JP3504658B2 (ja) 2004-03-08
EP0583265A1 (de) 1994-02-23
JPH06506355A (ja) 1994-07-21

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Legal Events

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REN Ceased due to non-payment of the annual fee