US5498538A
(en)
*
|
1990-02-15 |
1996-03-12 |
The University Of North Carolina At Chapel Hill |
Totally synthetic affinity reagents
|
US5747334A
(en)
*
|
1990-02-15 |
1998-05-05 |
The University Of North Carolina At Chapel Hill |
Random peptide library
|
CA2118806A1
(en)
*
|
1991-09-18 |
1993-04-01 |
William J. Dower |
Method of synthesizing diverse collections of oligomers
|
US5639603A
(en)
*
|
1991-09-18 |
1997-06-17 |
Affymax Technologies N.V. |
Synthesizing and screening molecular diversity
|
WO1993021203A1
(en)
*
|
1992-04-15 |
1993-10-28 |
The Johns Hopkins University |
Synthesis of diverse and useful collections of oligonucleotides
|
JPH08505524A
(ja)
*
|
1992-11-10 |
1996-06-18 |
イグジス, インコーポレイティッド |
溶液中で拘束された二次コンホメーションを有する可溶性ペプチド、およびその製造方法
|
US6165778A
(en)
*
|
1993-11-02 |
2000-12-26 |
Affymax Technologies N.V. |
Reaction vessel agitation apparatus
|
US5503805A
(en)
*
|
1993-11-02 |
1996-04-02 |
Affymax Technologies N.V. |
Apparatus and method for parallel coupling reactions
|
CN1134156A
(zh)
*
|
1993-11-02 |
1996-10-23 |
阿菲马克斯技术公司 |
合成和筛选多种分子
|
US5587471A
(en)
*
|
1994-01-11 |
1996-12-24 |
Isis Pharmaceuticals, Inc. |
Method of making oligonucleotide libraries
|
US6117679A
(en)
|
1994-02-17 |
2000-09-12 |
Maxygen, Inc. |
Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
|
US6995017B1
(en)
|
1994-02-17 |
2006-02-07 |
Maxygen, Inc. |
Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
|
US6165793A
(en)
*
|
1996-03-25 |
2000-12-26 |
Maxygen, Inc. |
Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
|
US6335160B1
(en)
|
1995-02-17 |
2002-01-01 |
Maxygen, Inc. |
Methods and compositions for polypeptide engineering
|
US6395547B1
(en)
|
1994-02-17 |
2002-05-28 |
Maxygen, Inc. |
Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
|
US5605793A
(en)
*
|
1994-02-17 |
1997-02-25 |
Affymax Technologies N.V. |
Methods for in vitro recombination
|
US6406855B1
(en)
|
1994-02-17 |
2002-06-18 |
Maxygen, Inc. |
Methods and compositions for polypeptide engineering
|
US5604097A
(en)
*
|
1994-10-13 |
1997-02-18 |
Spectragen, Inc. |
Methods for sorting polynucleotides using oligonucleotide tags
|
US5695934A
(en)
*
|
1994-10-13 |
1997-12-09 |
Lynx Therapeutics, Inc. |
Massively parallel sequencing of sorted polynucleotides
|
US5717085A
(en)
*
|
1994-11-23 |
1998-02-10 |
Terrapin Technologies, Inc. |
Process for preparing codon amidites
|
ATE382630T1
(de)
*
|
1995-09-11 |
2008-01-15 |
Jolla Cancer Res Found |
Moleküle, die sich in ausgewählten organen oder geweben in-vivo einfinden
|
US6743892B1
(en)
|
1995-09-11 |
2004-06-01 |
La Jolla Cancer Research Foundation |
Molecules that home to a selected organ in vivo
|
US6068829A
(en)
|
1995-09-11 |
2000-05-30 |
The Burnham Institute |
Method of identifying molecules that home to a selected organ in vivo
|
US5622699A
(en)
*
|
1995-09-11 |
1997-04-22 |
La Jolla Cancer Research Foundation |
Method of identifying molecules that home to a selected organ in vivo
|
US6506602B1
(en)
|
1996-03-25 |
2003-01-14 |
Maxygen, Inc. |
Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
|
US6096548A
(en)
|
1996-03-25 |
2000-08-01 |
Maxygen, Inc. |
Method for directing evolution of a virus
|
US6576239B1
(en)
|
1996-09-10 |
2003-06-10 |
The Burnham Institute |
Angiogenic homing molecules and conjugates derived therefrom
|
US6153410A
(en)
*
|
1997-03-25 |
2000-11-28 |
California Institute Of Technology |
Recombination of polynucleotide sequences using random or defined primers
|
WO1999023107A1
(en)
|
1997-10-31 |
1999-05-14 |
Maxygen, Incorporated |
Modification of virus tropism and host range by viral genome shuffling
|
IL136574A0
(en)
|
1997-12-08 |
2001-06-14 |
California Inst Of Techn |
A method for forming a polynucleotide of desired properties
|
US6541011B2
(en)
|
1998-02-11 |
2003-04-01 |
Maxygen, Inc. |
Antigen library immunization
|
US6232287B1
(en)
|
1998-03-13 |
2001-05-15 |
The Burnham Institute |
Molecules that home to various selected organs or tissues
|
US6365408B1
(en)
|
1998-06-19 |
2002-04-02 |
Maxygen, Inc. |
Methods of evolving a polynucleotides by mutagenesis and recombination
|
EP1165775A2
(de)
|
1999-03-05 |
2002-01-02 |
Maxygen, Inc. |
Rekombination von insertionsmodifizierten nucleinsäuren
|
CN1109185C
(zh)
*
|
1999-06-14 |
2003-05-21 |
深圳市怡诺威实业发展有限公司 |
免拆式汽车发动机保养设备
|
IL149809A0
(en)
*
|
1999-12-15 |
2002-11-10 |
Genentech Inc |
Shotgun scanning, a combinatorial method for mapping functional protein epitopes
|
WO2001055451A1
(en)
|
2000-01-28 |
2001-08-02 |
Linden Technologies, Inc. |
C-3' protected monomeric nucleotides and synthesis of oligonucleotides on solid support
|
US7452964B2
(en)
|
2001-09-07 |
2008-11-18 |
Board Of Regents, The University Of Texas System |
Compositions and methods of use of targeting peptides against placenta and adipose tissues
|
US7420030B2
(en)
|
2000-09-08 |
2008-09-02 |
The Board Of Regents Of The University Of Texas System |
Aminopeptidase A (APA) targeting peptides for the treatment of cancer
|
US20040170955A1
(en)
|
2000-09-08 |
2004-09-02 |
Wadih Arap |
Human and mouse targeting peptides identified by phage display
|
WO2003078623A1
(fr)
|
2002-03-19 |
2003-09-25 |
Fujitsu Limited |
Molecule fonctionnelle et son procede de production
|
US7544767B2
(en)
|
2002-04-05 |
2009-06-09 |
Burnham Institute For Medical Research |
HMGN2 peptides and related molecules that selectively home to tumor blood vessels and tumor cells
|
JP4753578B2
(ja)
|
2002-06-03 |
2011-08-24 |
ジェネンテック, インコーポレイテッド |
合成抗体ファージライブラリー
|
US7785903B2
(en)
|
2004-04-09 |
2010-08-31 |
Genentech, Inc. |
Variable domain library and uses
|
CN103172738A
(zh)
|
2005-06-30 |
2013-06-26 |
Abbvie公司 |
Il-12/p40结合蛋白
|
US7612181B2
(en)
|
2005-08-19 |
2009-11-03 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
KR101544108B1
(ko)
|
2006-09-08 |
2015-08-13 |
애브비 바하마스 리미티드 |
인터루킨-13 결합 단백질
|
EP2214708A4
(de)
|
2007-10-26 |
2011-01-12 |
Centocor Ortho Biotech Inc |
Vektoren, wirtszellen und herstellungsverfahren und verwendungen
|
KR20110014607A
(ko)
|
2008-04-29 |
2011-02-11 |
아보트 러보러터리즈 |
이원 가변 도메인 면역글로불린 및 이의 용도
|
WO2009136382A2
(en)
|
2008-05-09 |
2009-11-12 |
Abbott Gmbh & Co. Kg |
Antibodies to receptor of advanced glycation end products (rage) and uses thereof
|
MX2010013239A
(es)
|
2008-06-03 |
2011-02-24 |
Abbott Lab |
Inmunoglobulinas de dominio variable doble y usos de las mismas.
|
UY31861A
(es)
|
2008-06-03 |
2010-01-05 |
Abbott Lab |
Inmunoglobulina con dominio variable dual y usos de la misma
|
MX2010014574A
(es)
|
2008-07-08 |
2011-04-27 |
Abbott Lab |
Inmunoglobulinas de dominio variable dual para prostaglandina e2 y usos de las mismas.
|
SG172855A1
(en)
|
2009-01-29 |
2011-08-29 |
Abbott Lab |
Il-1 binding proteins
|
NZ611324A
(en)
|
2009-03-05 |
2015-02-27 |
Abbvie Inc |
Il-17 binding proteins
|
PE20121647A1
(es)
|
2009-08-29 |
2012-12-31 |
Abbvie Inc |
Proteinas terapeuticas de union a dll4
|
UY32870A
(es)
|
2009-09-01 |
2011-02-28 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
RU2012119756A
(ru)
|
2009-10-15 |
2013-11-20 |
Эбботт Лэборетриз |
Иммуноглобулины с двумя вариабельными доменами и их применение
|
UY32979A
(es)
|
2009-10-28 |
2011-02-28 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
TW201121568A
(en)
|
2009-10-31 |
2011-07-01 |
Abbott Lab |
Antibodies to receptor for advanced glycation end products (RAGE) and uses thereof
|
WO2011109298A2
(en)
|
2010-03-02 |
2011-09-09 |
Abbott Laboratories |
Therapeutic dll4 binding proteins
|
UY33386A
(es)
|
2010-05-14 |
2011-12-30 |
Abbott Laboratoires |
Proteínas de unión a il-1
|
TW201206473A
(en)
|
2010-08-03 |
2012-02-16 |
Abbott Lab |
Dual variable domain immunoglobulins and uses thereof
|
SI3333188T1
(sl)
|
2010-08-19 |
2022-04-29 |
Zoetis Belgium S.A. |
Protitelesa proti NGF in njihova uporaba
|
JP2013539364A
(ja)
|
2010-08-26 |
2013-10-24 |
アッヴィ・インコーポレイテッド |
二重可変ドメイン免疫グロブリンおよびその使用
|
WO2012088094A2
(en)
|
2010-12-21 |
2012-06-28 |
Abbott Laboratories |
Il-1 binding proteins
|
EP2771360A1
(de)
|
2011-10-24 |
2014-09-03 |
AbbVie Inc. |
Gegen sclerostin gerchtet immunbinder
|
MX2014008101A
(es)
|
2011-12-30 |
2014-09-25 |
Abbvie Inc |
Proteinas de union especificas duales dirigidas contra il-13 y/o il-17.
|
CA2875783C
(en)
|
2012-06-06 |
2018-12-11 |
Zoetis Llc |
Caninized anti-ngf antibodies and methods thereof
|
AR091755A1
(es)
|
2012-07-12 |
2015-02-25 |
Abbvie Inc |
Proteinas de union a il-1
|
KR20200079565A
(ko)
|
2012-08-31 |
2020-07-03 |
이뮤노젠 아이엔씨 |
엽산 수용체 1의 검출을 위한 진단성 검정 및 키트
|
TW201811825A
(zh)
|
2012-11-01 |
2018-04-01 |
美商艾伯維有限公司 |
抗-vegf/dll4雙重可變區域免疫球蛋白及其用途
|
WO2014100542A1
(en)
|
2012-12-21 |
2014-06-26 |
Abbvie, Inc. |
High-throughput antibody humanization
|
CA2906407A1
(en)
|
2013-03-14 |
2014-09-18 |
Abbott Laboratories |
Hcv ns3 recombinant antigens and mutants thereof for improved antibody detection
|
JP6739329B2
(ja)
|
2013-03-14 |
2020-08-12 |
アボット・ラボラトリーズAbbott Laboratories |
Hcvコア脂質結合ドメインモノクローナル抗体
|
MX362075B
(es)
|
2013-03-14 |
2019-01-07 |
Abbott Lab |
Ensayo de combinación de antígeno-anticuerpo del virus de la hepatitis c (vhc) y métodos y composiciones para usarlo.
|
TW201512219A
(zh)
|
2013-03-15 |
2015-04-01 |
Abbvie Inc |
針對IL-1β及/或IL-17之雙特異性結合蛋白
|
GB201406767D0
(en)
|
2014-04-15 |
2014-05-28 |
Cancer Rec Tech Ltd |
Humanized anti-Tn-MUC1 antibodies anf their conjugates
|
WO2016094881A2
(en)
|
2014-12-11 |
2016-06-16 |
Abbvie Inc. |
Lrp-8 binding proteins
|
TW201710286A
(zh)
|
2015-06-15 |
2017-03-16 |
艾伯維有限公司 |
抗vegf、pdgf及/或其受體之結合蛋白
|
JP6751165B2
(ja)
|
2016-06-08 |
2020-09-02 |
アッヴィ・インコーポレイテッド |
抗b7−h3抗体及び抗体薬物コンジュゲート
|
KR20240065333A
(ko)
|
2016-11-16 |
2024-05-14 |
얀센 바이오테크 인코포레이티드 |
항-il23 특이적 항체로 건선을 치료하는 방법
|
EP3544628A4
(de)
|
2016-11-23 |
2020-11-18 |
Immunoah Therapeutics, Inc. |
4-1bb-bindende proteine und verwendungen davon
|
JP7069476B2
(ja)
|
2017-01-06 |
2022-05-18 |
博奥信生物技▲術▼(南京)有限公司 |
ErbB2抗体およびその使用
|
EP3573658A4
(de)
|
2017-01-30 |
2021-07-21 |
Janssen Biotech, Inc. |
Anti-tnf-antikörper, zusammensetzungen und verfahren zur behandlung von aktiver psoriatischer arthritis
|
MX2019009377A
(es)
|
2017-02-07 |
2019-12-11 |
Janssen Biotech Inc |
Anticuerpos anti-tnf, composiciones y metodos para el tratamiento de la espondilitis anquilosante activa.
|
US11680110B2
(en)
|
2017-07-31 |
2023-06-20 |
Hoffmann-La Roche Inc. |
Three-dimensional structure-based humanization method
|
TW201922780A
(zh)
|
2017-09-25 |
2019-06-16 |
美商健生生物科技公司 |
以抗il12/il23抗體治療狼瘡之安全且有效之方法
|
EP3694552A1
(de)
|
2017-10-10 |
2020-08-19 |
Tilos Therapeutics, Inc. |
Anti-lap-antikörper und verwendungen davon
|
CN111989117A
(zh)
|
2018-02-14 |
2020-11-24 |
维埃拉生物股份有限公司 |
麦克唐纳猫肉瘤(fms)样酪氨酸激酶3受体配体(flt3l)的抗体及其用于治疗自身免疫性疾病和炎性疾病的用途
|
IL276896B2
(en)
|
2018-03-05 |
2024-06-01 |
Janssen Biotech Inc |
Methods for treating Crohn's disease with a specific anti-IL23 antibody
|
RU2020129265A
(ru)
|
2018-03-12 |
2022-04-12 |
ЗОИТИС СЕРВИСЕЗ ЭлЭлСи |
Антитела против ngf и связанные с ними способы
|
EP3824295A4
(de)
|
2018-07-18 |
2022-04-27 |
Janssen Biotech, Inc. |
Prädiktoren mit verzögerter wirkung nach behandlung mit anti-il23-spezifischem antikörper
|
FI3883606T3
(fi)
|
2018-09-24 |
2023-09-07 |
Janssen Biotech Inc |
Turvallinen ja tehokas menetelmä haavaisen paksusuolitulehduksen hoitamiseksi anti-il12/il23-vasta-aineella
|
EP3863722A2
(de)
|
2018-10-10 |
2021-08-18 |
Tilos Theapeutics, Inc. |
Anti-lap-antikörper und verwendungen davon
|
BR112021009287A2
(pt)
|
2018-11-20 |
2021-10-26 |
Janssen Biotech, Inc. |
Método seguro e eficaz para tratar psoríase com anticorpo específico anti-il-23
|
US20200197517A1
(en)
|
2018-12-18 |
2020-06-25 |
Janssen Biotech, Inc. |
Safe and Effective Method of Treating Lupus with Anti-IL12/IL23 Antibody
|
KR20210141990A
(ko)
|
2019-03-14 |
2021-11-23 |
얀센 바이오테크 인코포레이티드 |
항-il12/il23 항체 조성물을 생성하기 위한 제조 방법
|
EP3941934A4
(de)
|
2019-03-18 |
2022-12-07 |
Janssen Biotech, Inc. |
Verfahren zur behandlung von psoriasis bei kindern mit anti-il12/il23-antikörper
|
JP2022534020A
(ja)
|
2019-05-23 |
2022-07-27 |
ヤンセン バイオテツク,インコーポレーテツド |
Il-23及びtnfアルファに対する抗体の併用療法による炎症性腸疾患の治療方法
|
AR124681A1
(es)
|
2021-01-20 |
2023-04-26 |
Abbvie Inc |
Conjugados anticuerpo-fármaco anti-egfr
|
EP4308603A1
(de)
|
2021-03-17 |
2024-01-24 |
Receptos Llc |
Verfahren zur behandlung von atopischer dermatitis mit anti-il-13-antikörpern
|