ATE171479T1 - Verfahren zur herstellung von neuen biopolymeren - Google Patents

Verfahren zur herstellung von neuen biopolymeren

Info

Publication number
ATE171479T1
ATE171479T1 AT92908537T AT92908537T ATE171479T1 AT E171479 T1 ATE171479 T1 AT E171479T1 AT 92908537 T AT92908537 T AT 92908537T AT 92908537 T AT92908537 T AT 92908537T AT E171479 T1 ATE171479 T1 AT E171479T1
Authority
AT
Austria
Prior art keywords
nucleic acid
acid sequences
mixtures
new biopolymers
properties
Prior art date
Application number
AT92908537T
Other languages
German (de)
English (en)
Inventor
Karsten Henco
Manfred Eigen
Original Assignee
Evotec Biosystems Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6429722&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE171479(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Evotec Biosystems Gmbh filed Critical Evotec Biosystems Gmbh
Application granted granted Critical
Publication of ATE171479T1 publication Critical patent/ATE171479T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1058Directional evolution of libraries, e.g. evolution of libraries is achieved by mutagenesis and screening or selection of mixed population of organisms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1079Screening libraries by altering the phenotype or phenotypic trait of the host

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Ecology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
AT92908537T 1991-04-16 1992-04-14 Verfahren zur herstellung von neuen biopolymeren ATE171479T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4112440A DE4112440C1 (Direct) 1991-04-16 1991-04-16

Publications (1)

Publication Number Publication Date
ATE171479T1 true ATE171479T1 (de) 1998-10-15

Family

ID=6429722

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92908537T ATE171479T1 (de) 1991-04-16 1992-04-14 Verfahren zur herstellung von neuen biopolymeren

Country Status (5)

Country Link
EP (1) EP0583265B1 (Direct)
JP (1) JP3504658B2 (Direct)
AT (1) ATE171479T1 (Direct)
DE (2) DE4112440C1 (Direct)
WO (1) WO1992018645A1 (Direct)

Families Citing this family (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5849545A (en) * 1992-05-11 1998-12-15 Evotec Biosystems Gmbh Substrate material for simultaneously binding genotypic and phenotypic substances
DE4237381C1 (de) * 1992-11-05 1994-04-28 Diagen Inst Molekularbio Trägermaterial zur simultanen Bindung genotypischer und phänotypischer Substanzen
DE4343591A1 (de) * 1993-12-21 1995-06-22 Evotec Biosystems Gmbh Verfahren zum evolutiven Design und Synthese funktionaler Polymere auf der Basis von Formenelementen und Formencodes
US6165793A (en) * 1996-03-25 2000-12-26 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
US5837458A (en) 1994-02-17 1998-11-17 Maxygen, Inc. Methods and compositions for cellular and metabolic engineering
US6309883B1 (en) 1994-02-17 2001-10-30 Maxygen, Inc. Methods and compositions for cellular and metabolic engineering
US6995017B1 (en) 1994-02-17 2006-02-07 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
US6335160B1 (en) 1995-02-17 2002-01-01 Maxygen, Inc. Methods and compositions for polypeptide engineering
US6117679A (en) 1994-02-17 2000-09-12 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
EP0714980A1 (en) * 1994-12-02 1996-06-05 Institut Pasteur Hypermutagenesis
WO1996017056A1 (en) * 1994-12-02 1996-06-06 Institut Pasteur Hypermutagenesis
US6936289B2 (en) 1995-06-07 2005-08-30 Danisco A/S Method of improving the properties of a flour dough, a flour dough improving composition and improved food products
JPH1066577A (ja) * 1996-08-07 1998-03-10 Novo Nordisk As 核酸プールおよびその製造方法
US8207093B2 (en) 1997-01-21 2012-06-26 The General Hospital Corporation Selection of proteins using RNA-protein fusions
PT1712623E (pt) 1997-01-21 2011-12-21 Gen Hospital Corp Selecção de proteínas utilizando fusões de arn-proteína
US6261804B1 (en) 1997-01-21 2001-07-17 The General Hospital Corporation Selection of proteins using RNA-protein fusions
US6153410A (en) * 1997-03-25 2000-11-28 California Institute Of Technology Recombination of polynucleotide sequences using random or defined primers
EP1559788A1 (en) 1997-04-09 2005-08-03 Danisco A/S Use lipase for improving doughs and baked products
AU754377B2 (en) * 1997-09-03 2002-11-14 Merck Patent Gesellschaft Mit Beschrankter Haftung Methods for protein screening
US6927025B1 (en) 1997-09-03 2005-08-09 Biovation Limited Methods for protein screening
EP1003853B1 (en) * 1997-09-03 2005-11-30 Biovation Limited Methods for protein screening
CA2313380C (en) 1997-12-08 2008-12-30 California Institute Of Technology Method for creating polynucleotide and polypeptide sequences
US7153655B2 (en) 1998-06-16 2006-12-26 Alligator Bioscience Ab Method for in vitro molecular evolution of protein function involving the use of exonuclease enzyme and two populations of parent polynucleotide sequence
WO1999065927A2 (en) * 1998-06-17 1999-12-23 Maxygen, Inc. Method for producing polynucleotides with desired properties
US6846655B1 (en) 1998-06-29 2005-01-25 Phylos, Inc. Methods for generating highly diverse libraries
AU752215B2 (en) 1998-07-21 2002-09-12 Dupont Nutrition Biosciences Aps Foodstuff
WO2000009464A1 (en) 1998-08-17 2000-02-24 Phylos, Inc. Identification of compound-protein interactions using libraries of protein-nucleic acid fusion molecules
DE19953854C2 (de) 1999-11-09 2002-01-17 Max Planck Gesellschaft Verfahren zur Herstellung von Biopolymeren mit veränderten Eigenschaften
WO2001053539A1 (en) 2000-01-24 2001-07-26 Phylos, Inc. Sensitive, multiplexed diagnostic assays for protein analysis
US7022479B2 (en) 2000-01-24 2006-04-04 Compound Therapeutics, Inc. Sensitive, multiplexed diagnostic assays for protein analysis
US6958213B2 (en) 2000-12-12 2005-10-25 Alligator Bioscience Ab Method for in vitro molecular evolution of protein function
US20020086292A1 (en) 2000-12-22 2002-07-04 Shigeaki Harayama Synthesis of hybrid polynucleotide molecules using single-stranded polynucleotide molecules
US20020146732A1 (en) 2001-02-02 2002-10-10 Padgett Hal S. Method of increasing complementarity in a heteroduplex
US7838219B2 (en) 2001-02-02 2010-11-23 Novici Biotech Llc Method of increasing complementarity in a heteroduplex
US7582423B2 (en) 2001-02-02 2009-09-01 Novici Biotech Llc Population of polynucleotide sequence variants
BR0209154A (pt) 2001-05-18 2004-07-20 Danisco Processo de preparação de uma massa com uma enzima
EP1840211A1 (en) 2001-10-31 2007-10-03 Danisco A/S Pyranosone dehydratase from phanerochaete chrysosporium
US7078211B2 (en) 2002-02-01 2006-07-18 Large Scale Biology Corporation Nucleic acid molecules encoding endonucleases and methods of use thereof
EP1504098B2 (en) 2002-05-17 2011-02-09 Alligator Bioscience AB A method for in vitro molecular evolution of protein function
AU2003254356B2 (en) * 2002-07-17 2006-06-08 Unilever Plc Skin care cosmetic compositions containing carboxyalkylates of branched alcohols and/or alkoxylates thereof
CA2511252C (en) 2003-01-17 2015-04-14 Danisco A/S Production of at least one emulsifier in a foodstuff using a lipid acyltransferase enzyme
US7955814B2 (en) 2003-01-17 2011-06-07 Danisco A/S Method
MXPA05007653A (es) 2003-01-17 2005-09-30 Danisco Metodo.
US20050196766A1 (en) 2003-12-24 2005-09-08 Soe Jorn B. Proteins
US7335504B2 (en) 2003-06-18 2008-02-26 Direvo Biotechnology Ag Engineered enzymes and uses thereof
WO2005066347A1 (en) 2003-12-24 2005-07-21 Danisco A/S Proteins
GB0716126D0 (en) 2007-08-17 2007-09-26 Danisco Process
US7718408B2 (en) 2003-12-24 2010-05-18 Danisco A/S Method
GB0405637D0 (en) 2004-03-12 2004-04-21 Danisco Protein
NZ551378A (en) 2004-07-16 2009-06-26 Danisco Enzymatic oil-degumming method
GB0421598D0 (en) 2004-09-29 2004-10-27 Cambridge Advanced Tech Modification of plant development and morphology
GB0422052D0 (en) 2004-10-04 2004-11-03 Dansico As Enzymes
GB0423139D0 (en) 2004-10-18 2004-11-17 Danisco Enzymes
CN101611141B (zh) 2006-12-14 2014-05-07 帝斯曼知识产权资产管理有限公司 R-hnl随机变体及其用于制备光学纯的空间位阻氰醇的用途
MX2009008021A (es) 2007-01-25 2009-08-07 Danisco Produccion de una aciltransferasa de lipido de celulas de bacillus licheniformis transformadas.
US20080220498A1 (en) 2007-03-06 2008-09-11 Cervin Marguerite A Variant Buttiauxella sp. phytases having altered properties
US8143046B2 (en) 2007-02-07 2012-03-27 Danisco Us Inc., Genencor Division Variant Buttiauxella sp. phytases having altered properties
US8093016B2 (en) 2007-05-21 2012-01-10 Danisco Us Inc. Use of an aspartic protease (NS24) signal sequence for heterologous protein expression
PL3118309T3 (pl) 2008-04-18 2021-05-31 Danisco Us Inc. Warianty fitazy buttiauxella sp.
DK2281034T3 (en) 2008-04-30 2016-01-25 Dupont Nutrition Biosci Aps A method using alcohol dehydrogenase Pseudoglucanobacter saccharoketogenes
GB0908770D0 (en) 2009-04-24 2009-07-01 Danisco Method
CA2761767A1 (en) 2009-05-19 2010-11-25 Danisco A/S Use of amylase and lipolytic enzyme in bread
AR077042A1 (es) 2009-06-12 2011-07-27 Danisco Metodo para tratar una composicion que contiene pirofiofitina
GB0920089D0 (en) 2009-11-17 2009-12-30 Danisco Method
EP2524023A1 (en) 2010-01-13 2012-11-21 Basf Se Novel mannanase variants
PL2545150T3 (pl) 2010-03-12 2019-01-31 Dupont Nutrition Biosciences Aps Sposób
WO2011114251A1 (en) 2010-03-18 2011-09-22 Danisco A/S Foodstuff
AR081950A1 (es) 2010-06-17 2012-10-31 Danisco Proceso de tratamiento de semillas que contienen aceite
GB201011513D0 (en) 2010-07-08 2010-08-25 Danisco Method
CA3004088A1 (en) 2011-02-23 2012-08-30 Dupont Nutrition Biosciences Aps Enzymatic treatment of plant oil
AR085251A1 (es) 2011-02-23 2013-09-18 Danisco Proceso para tratar aceite vegetal
CN103797114A (zh) 2011-02-23 2014-05-14 杜邦营养生物科学有限公司 生产能够水解叶绿素或叶绿素衍生物的重组酶的方法
AU2012241055A1 (en) 2011-04-08 2013-08-15 Danisco Us, Inc. Compositions
EP2691530B1 (en) 2011-06-10 2018-03-07 Oregon Health & Science University Cmv glycoproteins and recombinant vectors
WO2013104660A1 (en) 2012-01-13 2013-07-18 Dupont Nutrition Biosciences Aps Process for treating a plant oil comprising hydrolysing chlorophyll or a chlorophyll derivative and involving partial caustic neutralisation
WO2013104659A2 (en) 2012-01-13 2013-07-18 Dupont Nutrition Biosciences Aps Process
WO2013160372A1 (en) 2012-04-27 2013-10-31 Dupont Nutrition Biosciences Aps Process for treating plant oil involving addition of serial doses of chlorophyll or chlorophyll derivative degrading enzyme
WO2013160374A1 (en) 2012-04-27 2013-10-31 Dupont Nutrition Biosciences Aps Process for refining crude plant oil involving enzymatic hydrolysis and gum recycling
WO2014063097A1 (en) 2012-10-19 2014-04-24 Danisco Us Inc. Stabilization of biomimetic membranes
DK3083936T3 (en) 2013-12-19 2018-10-22 Danisco Us Inc USE OF HYDROPHOBINES TO INCREASE GAS TRANSFER IN AEROBE FERMENTATION PROCESSES
WO2015150372A1 (en) 2014-04-01 2015-10-08 Dupont Nutrition Biosciences Aps Method for increasing crude palm oil yields
WO2016062855A1 (en) 2014-10-24 2016-04-28 Dupont Nutrition Biosciences Aps Proline tolerant tripeptidyl peptidases and uses thereof
BR112017007949A2 (pt) 2014-10-24 2018-01-23 Danisco Us Inc método para produção de álcool pelo uso de uma tripeptidil-peptidase
MX2017016501A (es) 2015-06-26 2018-03-12 Dupont Nutrition Biosci Aps Aminopeptidasas para hidrolizados de proteinas.
WO2017147060A1 (en) 2016-02-25 2017-08-31 Dupont Nutrition Biosciences Aps Method for producing a protein hydrolysate employing an aspergillus fumigatus tripeptidyl peptidase
DE102023001827A1 (de) 2023-04-19 2024-10-24 Horst Wochnowski Verfahren und dazugehörige Vorrichtung zum Züchten von in Gewässern Mikroplastik zersetzenden und abbauenden Mikroorganismenstämme durch einen künstlich herbeigeführten und beschleunigten Evolutions- und Selektionsprozess

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0285123A3 (en) * 1987-04-03 1989-02-01 Stabra AG A method for complete mutagenesis of nucleic acids
ATE168416T1 (de) * 1989-10-05 1998-08-15 Optein Inc Zellfreie synthese und isolierung von genen und polypeptiden
AU8498091A (en) * 1990-08-02 1992-03-02 Regents Of The University Of Colorado, The Systematic polypeptide evolution by reverse translation

Also Published As

Publication number Publication date
DE59209506D1 (de) 1998-10-29
DE4112440C1 (Direct) 1992-10-22
WO1992018645A1 (de) 1992-10-29
EP0583265B1 (de) 1998-09-23
JP3504658B2 (ja) 2004-03-08
EP0583265A1 (de) 1994-02-23
JPH06506355A (ja) 1994-07-21

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