ATE16567T1 - Intravenoes injektierbares globulin aus immunserum und verfahren zu seiner herstellung. - Google Patents

Intravenoes injektierbares globulin aus immunserum und verfahren zu seiner herstellung.

Info

Publication number
ATE16567T1
ATE16567T1 AT82107262T AT82107262T ATE16567T1 AT E16567 T1 ATE16567 T1 AT E16567T1 AT 82107262 T AT82107262 T AT 82107262T AT 82107262 T AT82107262 T AT 82107262T AT E16567 T1 ATE16567 T1 AT E16567T1
Authority
AT
Austria
Prior art keywords
immune serum
globulin
production
composition
intravenous injectable
Prior art date
Application number
AT82107262T
Other languages
English (en)
Inventor
Robert A Tenold
Original Assignee
Miles Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Miles Lab filed Critical Miles Lab
Application granted granted Critical
Publication of ATE16567T1 publication Critical patent/ATE16567T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591—Stabilisation, fragmentation

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mycology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT82107262T 1981-08-24 1982-08-11 Intravenoes injektierbares globulin aus immunserum und verfahren zu seiner herstellung. ATE16567T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/295,916 US4396608A (en) 1981-08-24 1981-08-24 Intravenously injectable immune serum globulin
EP82107262A EP0073371B1 (de) 1981-08-24 1982-08-11 Intravenös injektierbares Globulin aus Immunserum und Verfahren zu seiner Herstellung

Publications (1)

Publication Number Publication Date
ATE16567T1 true ATE16567T1 (de) 1985-12-15

Family

ID=23139776

Family Applications (1)

Application Number Title Priority Date Filing Date
AT82107262T ATE16567T1 (de) 1981-08-24 1982-08-11 Intravenoes injektierbares globulin aus immunserum und verfahren zu seiner herstellung.

Country Status (9)

Country Link
US (1) US4396608A (de)
EP (1) EP0073371B1 (de)
JP (2) JPH0694421B2 (de)
AT (1) ATE16567T1 (de)
AU (1) AU549204B2 (de)
CA (1) CA1183084A (de)
DE (1) DE3267593D1 (de)
ES (1) ES8306440A1 (de)
MX (1) MX7235E (de)

Families Citing this family (53)

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US4439421A (en) * 1982-08-30 1984-03-27 Baxter Travenol Laboratories, Inc. Stabilized gamma globulin concentrate
JPH08787B2 (ja) * 1982-08-30 1996-01-10 バクスター、インターナショナル、インコーポレイテッド ガンマグロブリン含有組成物の製造法
EP0122267A4 (de) * 1982-10-21 1986-09-24 Minneapolis Medical Res Founda Opsonine in peritonealer dialyse.
DK166763C (da) * 1983-03-16 1993-07-12 Immuno Ag Immunoglobulin-g-holdig fraktion
AT383737B (de) * 1983-03-16 1987-08-10 Immuno Ag Verfahren zur verwendung einer immunoglobulin-g enthaltenden fraktion
US4617379A (en) * 1983-06-14 1986-10-14 Miles Laboratories, Inc. High titer cytomegalovirus immune serum globulin
US4719290A (en) * 1983-09-02 1988-01-12 Armour Pharmaceutical Corporation Composition of intravenous immune globulin
US5161472A (en) * 1984-03-30 1992-11-10 Handy Barry L Multi-function draft implement
US4665159A (en) * 1985-11-07 1987-05-12 Miles Laboratories, Inc. High titer varicella-zoster immune globulin for intravenous administration
US4717564A (en) * 1985-11-07 1988-01-05 Miles Laboratories, Inc. High titer varicella-zoster immune globulin for intravenous administration
US4659563A (en) * 1986-01-27 1987-04-21 Miles Laboratories, Inc. High titer anti-respiratory syncytial virus intravenous immune globulin
US4717766A (en) * 1986-01-27 1988-01-05 Miles Laboratories, Inc. Method of preparing high titer anti-respiratory syncytial virus intravenous immune globulin
US5419906A (en) * 1986-04-08 1995-05-30 Miles Inc. Preparation of human immunoglobulin free of hepatitis C
US4762714A (en) * 1986-04-08 1988-08-09 Miles Laboratories, Inc. Preparation of retrovirus-free immunoglobulins
US5159064A (en) * 1986-04-08 1992-10-27 Miles Inc. Preparation of virus-free antibodies
US4948877A (en) * 1986-04-08 1990-08-14 Miles Laboratories, Inc. Preparation of retrovirus-free immunoglobulins
CA1310267C (en) * 1986-07-09 1992-11-17 Yutaka Hirao Process for heat treating chemically unmodified _-globulin
JPH07103045B2 (ja) * 1986-07-09 1995-11-08 株式会社ミドリ十字 非化学修飾γ−グロブリンの加熱処理方法
JP2547556B2 (ja) * 1987-02-06 1996-10-23 株式会社 ミドリ十字 ｒ−グロブリンの液状製剤
WO1989011298A1 (en) * 1988-05-27 1989-11-30 Centocor, Inc. Formulation for antibody reagents
EP0417193B1 (de) * 1988-05-27 1993-08-04 Centocor, Inc. Gefriergetrocknete formulierung für antikörperprodukte
US5945098A (en) * 1990-02-01 1999-08-31 Baxter International Inc. Stable intravenously-administrable immune globulin preparation
US5847086A (en) * 1991-06-20 1998-12-08 Centeon L.L.C. Therapeutic fragments of von Willebrand factor
DE4125625C2 (de) * 1991-08-02 1999-12-02 Octapharma Ag Glarus Verfahren zur Herstellung von virusinaktivierten Immunglobulinlösungen
US5258177A (en) * 1991-12-10 1993-11-02 Alpha Therapeutic Corporation IgA preparation and process of making the same
US6096216A (en) * 1994-06-09 2000-08-01 American National Red Cross Iodinated matrices for disinfecting biological fluids
US6267958B1 (en) 1995-07-27 2001-07-31 Genentech, Inc. Protein formulation
US6686191B1 (en) * 1995-09-22 2004-02-03 Bayer Healthcare Llc Preparation of virally inactivated intravenously injectable immune serum globulin
JP2000505078A (ja) * 1996-01-19 2000-04-25 イーライ・リリー・アンド・カンパニー 肥満症タンパク質製剤
AU1705197A (en) * 1996-01-19 1997-08-11 Eli Lilly And Company Obesity protein formulations
RU2122864C1 (ru) * 1996-12-26 1998-12-10 Московский научно-исследовательский институт эпидемиологии и микробиологии им.Г.Н.Габричевского Препарат иммуноглобулина для внутривенного введения и способ его получения
CA2232420A1 (en) * 1997-03-19 1998-09-19 The Green Cross Corporation Immunoglobulin preparation and preparation process thereof
WO1998044948A2 (en) * 1997-04-07 1998-10-15 Cangene Corporation Intravenous immune globulin formulation containing a non-ionic surface active agent with improved pharmacokinetic properties
US5886154A (en) 1997-06-20 1999-03-23 Lebing; Wytold R. Chromatographic method for high yield purification and viral inactivation of antibodies
US6955917B2 (en) * 1997-06-20 2005-10-18 Bayer Healthcare Llc Chromatographic method for high yield purification and viral inactivation of antibodies
RU2140289C1 (ru) * 1998-01-30 1999-10-27 Государственное унитарное предприятие "Иммунопрепарат" Способ получения внутривенного иммуноглобулина
US6106773A (en) * 1998-09-24 2000-08-22 American National Red Cross Pathogen inactivating compositions for disinfecting biological fluids
DE60334678D1 (de) * 2002-02-14 2010-12-09 Chugai Pharmaceutical Co Ltd Antikörper enthaltende pharmazeutische lösungen
US20040022792A1 (en) * 2002-06-17 2004-02-05 Ralph Klinke Method of stabilizing proteins at low pH
US20040033228A1 (en) 2002-08-16 2004-02-19 Hans-Juergen Krause Formulation of human antibodies for treating TNF-alpha associated disorders
EP1532983A1 (de) 2003-11-18 2005-05-25 ZLB Bioplasma AG Immunoglobulinpräparationen mit erhöhter Stabilität
JP2008543839A (ja) 2005-06-14 2008-12-04 アムジェン インコーポレーテッド 自己緩衝タンパク質製剤
WO2008045563A2 (en) * 2006-10-12 2008-04-17 Wyeth Modification of ionic strength in antibody-solutions to reduce opalescence/aggregates
US8883146B2 (en) 2007-11-30 2014-11-11 Abbvie Inc. Protein formulations and methods of making same
TWI532498B (zh) 2008-03-17 2016-05-11 巴克斯特保健公司 供免疫球蛋白及玻尿酸酶之皮下投藥之用的組合及方法
US8772461B2 (en) * 2008-04-15 2014-07-08 Grifols Therapeutics Inc. Two-stage ultrafiltration/diafiltration
CA2774053C (en) 2009-09-17 2015-04-28 Baxter Healthcare, S.A. Stable co-formulation of hyaluronidase and immunoglobulin, and methods of use thereof
DK2531218T3 (en) 2010-02-04 2019-04-01 Csl Behring Ag immunoglobulin
EP2361636A1 (de) 2010-02-26 2011-08-31 CSL Behring AG Immunglobulinpräparat und Aufbewahrungssystem für ein Immunglobulinpräparat
ES2381828B1 (es) 2012-03-20 2012-11-16 Grifols, S.A. PROCEDIMIENTO PARA OBTENER UNA COMPOSICION DE IgG MEDIANTE TRATAMIENTO TERMICO
JP6726666B2 (ja) 2014-12-03 2020-07-22 ツェー・エス・エル・ベーリング・アクチエンゲゼルシャフト 免疫グロブリンを含む安定性が高められた医薬製品
WO2018075818A1 (en) 2016-10-21 2018-04-26 Amgen Inc. Pharmaceutical formulations and methods of making the same
MA51747A (fr) * 2018-02-08 2020-12-16 Amgen Inc Formulation d'anticorps pharmaceutique à ph faible

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2500076C3 (de) * 1975-01-02 1982-11-18 SCHURA Blutderivate GmbH & Co KG, 4150 Krefeld Verfahren zur Gewinnung von intravenös-verträglichen Gammaglobulinen
CA1064396A (en) * 1975-02-18 1979-10-16 Myer L. Coval Fractional precipitation of gamma globulin with polyethylene glycol
US4124576A (en) * 1976-12-03 1978-11-07 Coval M L Method of producing intravenously injectable gamma globulin
JPS5822085B2 (ja) * 1977-07-19 1983-05-06 株式会社ミドリ十字 静注用ガンマ・グロブリン製剤
US4186192A (en) * 1978-12-18 1980-01-29 Cutter Laboratories, Inc. Stabilized immune serum globulin
US4374763A (en) * 1979-09-17 1983-02-22 Morishita Pharmaceutical Co., Ltd. Method for producing gamma-globulin for use in intravenous administration and method for producing a pharmaceutical preparation thereof
EP0498006A1 (de) * 1991-02-06 1992-08-12 International Business Machines Corporation Überlagerungsverfahren für den räumlichen Frequenzbereich und Struktur zur Messung der Übereinstimmung von Mustern
JPH07238036A (ja) * 1994-02-28 1995-09-12 Green Cross Corp:The 静注用グロブリン液状組成物のグロブリン二量体増加抑制方法

Also Published As

Publication number Publication date
MX7235E (es) 1988-01-26
ES515177A0 (es) 1983-06-01
JPS5843914A (ja) 1983-03-14
ES8306440A1 (es) 1983-06-01
JPH05208918A (ja) 1993-08-20
DE3267593D1 (en) 1986-01-02
AU549204B2 (en) 1986-01-16
AU8726582A (en) 1983-03-03
EP0073371B1 (de) 1985-11-21
JPH0761956B2 (ja) 1995-07-05
US4396608A (en) 1983-08-02
EP0073371A3 (en) 1983-09-21
EP0073371A2 (de) 1983-03-09
CA1183084A (en) 1985-02-26
JPH0694421B2 (ja) 1994-11-24

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EEIH Change in the person of patent owner
EELA Cancelled due to lapse of time