ATE162516T1 - Nichtmetabolisierbare clomiphene-analoge zur behandlung von tamoxifen-resistenten tumoren - Google Patents
Nichtmetabolisierbare clomiphene-analoge zur behandlung von tamoxifen-resistenten tumorenInfo
- Publication number
- ATE162516T1 ATE162516T1 AT93920100T AT93920100T ATE162516T1 AT E162516 T1 ATE162516 T1 AT E162516T1 AT 93920100 T AT93920100 T AT 93920100T AT 93920100 T AT93920100 T AT 93920100T AT E162516 T1 ATE162516 T1 AT E162516T1
- Authority
- AT
- Austria
- Prior art keywords
- metabolizable
- tamoxifen
- treatment
- resistant tumors
- clomiphene
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/24—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/25—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/43—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
- C07C211/44—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to only one six-membered aromatic ring
- C07C211/45—Monoamines
- C07C211/48—N-alkylated amines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US94530592A | 1992-09-15 | 1992-09-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE162516T1 true ATE162516T1 (de) | 1998-02-15 |
Family
ID=25482938
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT93920100T ATE162516T1 (de) | 1992-09-15 | 1993-08-16 | Nichtmetabolisierbare clomiphene-analoge zur behandlung von tamoxifen-resistenten tumoren |
Country Status (16)
Country | Link |
---|---|
US (2) | US5410080A (de) |
EP (1) | EP0660821B1 (de) |
JP (1) | JPH09500863A (de) |
KR (1) | KR100326962B1 (de) |
AT (1) | ATE162516T1 (de) |
AU (1) | AU672234B2 (de) |
CA (1) | CA2143000C (de) |
DE (1) | DE69316633T2 (de) |
DK (1) | DK0660821T3 (de) |
ES (1) | ES2112994T3 (de) |
FI (1) | FI951193A0 (de) |
GR (1) | GR3026236T3 (de) |
HU (1) | HUT71244A (de) |
NO (1) | NO950985L (de) |
NZ (1) | NZ255785A (de) |
WO (1) | WO1994006762A1 (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR008155A1 (es) * | 1996-09-06 | 1999-12-09 | Smithkline Beecham Corp | Uso de un compuesto de formula i para preparar un medicamento util para tratar y prevenir la enfermedad cardiovascular post menopausica en mujeres. |
DE69840126D1 (de) | 1997-08-15 | 2008-11-27 | Univ Duke | Verfahren zur prophylaxis oder behandlung von östrogen-abhängigen krankheiten |
UA113291C2 (xx) * | 2011-08-04 | 2017-01-10 | Метаболіти транскломіфену і їх застосування | |
JP2015535283A (ja) | 2012-11-02 | 2015-12-10 | レプロス セラピューティクス インコーポレイティド | 癌療法における使用のためのトランス−クロミフェン |
JP2017507961A (ja) * | 2014-03-11 | 2017-03-23 | レプロス セラピューティクス インコーポレイティド | 単一の溶媒を用いるクロミフェン合成 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2750416A (en) * | 1950-12-21 | 1956-06-12 | Rohm & Haas | Aminomethylphenols and method for their preparation |
US3143568A (en) * | 1961-01-25 | 1964-08-04 | Vismara Francesco Spa | Diarylamino-acetyl-aryl derivatives |
US3244705A (en) * | 1962-11-14 | 1966-04-05 | Richardson Merrell Inc | Triphenylhaloethylene derivatives |
CH373975A (de) * | 1963-07-20 | 1963-12-15 | Heierle Werner | Kronen-Verschluss für Flaschen |
FR3575M (fr) * | 1964-01-28 | 1965-10-04 | Richardson Merrell | Triphénylhalogénoéthylenes substitués. |
US3631109A (en) * | 1968-12-04 | 1971-12-28 | Uniroyal Inc | Beta beta'-bis(dialkylaminomethyl-4-hydroxy-benzylthio)dialkylethers |
GB2126576B (en) * | 1982-06-25 | 1985-06-19 | Farmos Group Limited | Alkane and alkene derivatives |
GB2196003A (en) * | 1986-09-11 | 1988-04-20 | Nat Res Dev | Iodo-and bromo-tamoxifen derivatives |
US5114951A (en) * | 1989-04-11 | 1992-05-19 | Burroughs Wellcome Company | Agents for combating multiple drug resistance |
US5130424A (en) * | 1990-08-01 | 1992-07-14 | Merrell Dow Pharmaceuticals Inc. | 4-amino-delta-4,6-steroids and their use as 5 alpha-reductase inhibitors |
-
1993
- 1993-08-16 AU AU50150/93A patent/AU672234B2/en not_active Ceased
- 1993-08-16 NZ NZ255785A patent/NZ255785A/en unknown
- 1993-08-16 AT AT93920100T patent/ATE162516T1/de not_active IP Right Cessation
- 1993-08-16 ES ES93920100T patent/ES2112994T3/es not_active Expired - Lifetime
- 1993-08-16 CA CA002143000A patent/CA2143000C/en not_active Expired - Fee Related
- 1993-08-16 DE DE69316633T patent/DE69316633T2/de not_active Expired - Fee Related
- 1993-08-16 HU HU9500775A patent/HUT71244A/hu unknown
- 1993-08-16 JP JP6508081A patent/JPH09500863A/ja not_active Ceased
- 1993-08-16 DK DK93920100T patent/DK0660821T3/da active
- 1993-08-16 WO PCT/US1993/007697 patent/WO1994006762A1/en active IP Right Grant
- 1993-08-16 KR KR1019950700991A patent/KR100326962B1/ko not_active IP Right Cessation
- 1993-08-16 EP EP93920100A patent/EP0660821B1/de not_active Expired - Lifetime
-
1994
- 1994-02-10 US US08/196,817 patent/US5410080A/en not_active Expired - Fee Related
- 1994-12-05 US US08/350,192 patent/US5681863A/en not_active Expired - Fee Related
-
1995
- 1995-03-14 FI FI951193A patent/FI951193A0/fi not_active Application Discontinuation
- 1995-03-14 NO NO950985A patent/NO950985L/no not_active Application Discontinuation
-
1998
- 1998-02-25 GR GR980400417T patent/GR3026236T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
NO950985D0 (no) | 1995-03-14 |
US5410080A (en) | 1995-04-25 |
DK0660821T3 (da) | 1998-09-21 |
FI951193A (fi) | 1995-03-14 |
US5681863A (en) | 1997-10-28 |
JPH09500863A (ja) | 1997-01-28 |
EP0660821B1 (de) | 1998-01-21 |
GR3026236T3 (en) | 1998-05-29 |
AU672234B2 (en) | 1996-09-26 |
KR100326962B1 (ko) | 2002-12-02 |
AU5015093A (en) | 1994-04-12 |
DE69316633D1 (de) | 1998-02-26 |
KR950703524A (ko) | 1995-09-20 |
ES2112994T3 (es) | 1998-04-16 |
NZ255785A (en) | 1997-05-26 |
HU9500775D0 (en) | 1995-05-29 |
HUT71244A (en) | 1995-11-28 |
NO950985L (no) | 1995-03-14 |
CA2143000C (en) | 2000-03-28 |
WO1994006762A1 (en) | 1994-03-31 |
FI951193A0 (fi) | 1995-03-14 |
EP0660821A1 (de) | 1995-07-05 |
CA2143000A1 (en) | 1994-03-31 |
DE69316633T2 (de) | 1998-05-20 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE249228T1 (de) | Verwendung von polyallylamin-polymeren zur herstellung eines medikamentes zur behandlung von hypercholesterolemia | |
ATE231519T1 (de) | Dinukleotide zur verwendung in der behandlung von lungenkrankheiten | |
KR880012217A (ko) | 캘콘 유도체를 사용한 종량 조직의 증식 억제방법 | |
ATE131165T1 (de) | Leukotrien-b4-antagonisten. | |
ATE220323T1 (de) | Methode zur behandlung von resistenten neoplasmen | |
KR890011596A (ko) | 불면증 치료용 의약품의 제조에 있어서 1,4-이치환-피페리디닐 화합물의 용도 | |
ATE137965T1 (de) | Verwendung von tomoxetine zur behandlung von funktionsstörungen der niedrigen harnwege | |
ATE162516T1 (de) | Nichtmetabolisierbare clomiphene-analoge zur behandlung von tamoxifen-resistenten tumoren | |
FI934680A0 (fi) | Arylmorfolin, framstaellning och anvaending | |
ATE99934T1 (de) | Heteroaryl-3-oxo-propannitril-derivate, nuetzlich zur behandlung von rheumatoider arthritis und anderen autoimmunkrankheiten. | |
EP0129891A3 (de) | Chinazolinon-Derivate, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammensetzungen | |
BR9708922A (pt) | Piridil-e pirimidil-piperazinas no tratamento de doenças causadas por substâncias usadas em excesso | |
ES8605803A1 (es) | Procedimiento para la fabricacion de nuevos compuestos cina-moicos | |
ATE24834T1 (de) | Verwendung von beta-(1-adamantyl)-alpha, alphadimethylethylamin zur herstellung eines arzneimittels zur behandlung von otitis externa bei hunden. | |
DE3277694D1 (en) | Hydrazinopyridazine compound, process for production thereof, and use thereof as medicament | |
ES2006099A6 (es) | Procedimiento para la obtencion de hidrocloruro de ciprofloxacina monohidrato. | |
DE3770481D1 (de) | Verwendung von imidazochinazolinen zur behandlung und verhinderung von nephritis. | |
ATE81465T1 (de) | Verwendung von 2-oxo-imidazolidin-derivaten zur behandlung von nierenkrankheiten. | |
EP0097468A3 (de) | Thio-naphthotriazole, Verfahren zu ihrer Herstellung und Verwendung bei der Behandlung von Allergien |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |