ATE155175T1 - Stereoisomerische anreicherung von 2-amino-3- hydroxy-3-phenyl-propionsäuren - Google Patents

Stereoisomerische anreicherung von 2-amino-3- hydroxy-3-phenyl-propionsäuren

Info

Publication number
ATE155175T1
ATE155175T1 AT92104752T AT92104752T ATE155175T1 AT E155175 T1 ATE155175 T1 AT E155175T1 AT 92104752 T AT92104752 T AT 92104752T AT 92104752 T AT92104752 T AT 92104752T AT E155175 T1 ATE155175 T1 AT E155175T1
Authority
AT
Austria
Prior art keywords
amino
hydroxy
phenyl
threo
propionic acids
Prior art date
Application number
AT92104752T
Other languages
English (en)
Inventor
Andrew L Zeitlin
Muppala S Raju
David I Stirling
Original Assignee
Celgene Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27418304&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE155175(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Celgene Corp filed Critical Celgene Corp
Application granted granted Critical
Publication of ATE155175T1 publication Critical patent/ATE155175T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00—Preparation of sulfones; Preparation of sulfoxides
    • C07C315/06—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/26—Separation; Purification; Stabilisation; Use of additives
    • C07C319/28—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P11/00—Preparation of sulfur-containing organic compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/829—Alcaligenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT92104752T 1991-03-27 1992-03-19 Stereoisomerische anreicherung von 2-amino-3- hydroxy-3-phenyl-propionsäuren ATE155175T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US67610291A 1991-03-27 1991-03-27
US68930091A 1991-04-22 1991-04-22
US07/844,724 US5346828A (en) 1991-03-27 1992-03-02 Stereoisomeric enrichment of 2-amino-3-hydroxy-3-phenylpropionic acids using d-threonine aldolase

Publications (1)

Publication Number Publication Date
ATE155175T1 true ATE155175T1 (de) 1997-07-15

Family

ID=27418304

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92104752T ATE155175T1 (de) 1991-03-27 1992-03-19 Stereoisomerische anreicherung von 2-amino-3- hydroxy-3-phenyl-propionsäuren

Country Status (17)

Country Link
US (1) US5346828A (de)
EP (1) EP0507153B1 (de)
JP (1) JP3142627B2 (de)
KR (1) KR100250513B1 (de)
AT (1) ATE155175T1 (de)
AU (1) AU645895B2 (de)
CA (1) CA2064349C (de)
CZ (1) CZ289218B6 (de)
DE (1) DE69220701T2 (de)
DK (1) DK0507153T3 (de)
ES (1) ES2106101T3 (de)
GR (1) GR3024971T3 (de)
HU (1) HU214305B (de)
IE (1) IE920866A1 (de)
IL (1) IL101268A (de)
NZ (1) NZ242040A (de)
SK (1) SK282932B6 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW397866B (en) 1993-07-14 2000-07-11 Bristol Myers Squibb Co Enzymatic processes for the resolution of enantiomeric mixtures of compounds useful as intermediates in the preparation of taxanes
JPH09506610A (ja) * 1993-12-17 1997-06-30 ディーエスエム エヌ．ブイ． フェニルセリンアミド、及びフェニルセリン／フェニルセリンアミド の調製
US7172885B2 (en) * 2004-12-10 2007-02-06 Cambrex North Brunswick, Inc. Thermostable omega-transaminases
JP4877227B2 (ja) * 2005-05-20 2012-02-15 味の素株式会社 Ｌ−セリン誘導体の製造方法およびこれに用いる酵素
US7518017B2 (en) 2006-02-17 2009-04-14 Idexx Laboratories Fenicol compounds and methods synthesizing 2-trifluoroacetamido-3-substituted propiophenone compounds
KR100758512B1 (ko) 2006-07-20 2007-09-14 엔자이텍 주식회사 효소적 방법에 의한 광학활성3-히드록시-3-페닐프로피온산과 광학활성3-아실옥시-3-페닐프로피온산의 제조 방법
US8470564B2 (en) 2009-01-08 2013-06-25 Codexis, Inc. Transaminase polypeptides
EP2401366B1 (de) 2009-02-26 2013-12-18 Codexis, Inc. Transaminase-biokatalysatoren
ES2644992T3 (es) 2009-06-22 2017-12-01 Codexis, Inc. Reacciones de transaminasa
DK2582799T3 (en) 2010-06-17 2018-02-12 Codexis Inc BIOCATALATORS AND PROCEDURES FOR THE SYNTHESIS OF (S) -3- (1-AMINOETHYL) -PHENOL
US8932836B2 (en) 2010-08-16 2015-01-13 Codexis, Inc. Biocatalysts and methods for the synthesis of (1R,2R)-2-(3,4-dimethoxyphenethoxy)cyclohexanamine
CN101941927B (zh) * 2010-09-28 2012-10-03 湖北美天生物科技有限公司 氟苯尼考中间体(1r,2r)-2-氨基-1–(4-(甲砜基)苯基)-1,3-丙二醇的合成方法
CN115611785B (zh) * 2022-12-19 2023-03-14 天津工微生物科技有限公司 (2r,3s)-2-氨基-3-羟基-3-(4-(甲基磺酰基)苯基)丙酸的纯化方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3733352A (en) * 1969-07-29 1973-05-15 Sumitomo Chemical Co Preparation of d-threo-1-p-methyl-sulfonylphenyl-2-dichloro-acet-amidopropane-1,3-diol
US3871958A (en) * 1972-03-04 1975-03-18 Ajinomoto Kk Biological method of producing serine and serinol derivatives
FR2378746A1 (fr) 1977-01-28 1978-08-25 Synthelabo Derives d'acides a-amines
US4235892A (en) * 1979-02-05 1980-11-25 Schering Corporation, Patent Dept. 1-Aryl-2-acylamido-3-fluoro-1-propanols, methods for their use as antibacterial agents and compositions useful therefor
US4492757A (en) * 1981-12-28 1985-01-08 Denki Kagaku Kogyo Kabushiki Kaisha Process for preparing L-threonine
US4582918A (en) * 1984-09-19 1986-04-15 Schering Corporation Preparation of intermediates for (threo)-1-aryl-2-acylamido-3-fluoro-1-propanols
US4677214A (en) * 1984-09-19 1987-06-30 Schering Corporation Intermediates for preparation of (threo)-1-aryl-2-acylamido-3-fluoro-1-propanols
DE3543021A1 (de) * 1985-12-05 1987-06-11 Boehringer Mannheim Gmbh Verbesserte verfahren zur herstellung von d-threo-1-(p-methylsulfonylphenyl) -2-dichloracetamido-propandiol-1,3-(thiamphenicol) sowie verwendung geeigneter zwischenprodukte
KR920701469A (ko) * 1989-05-15 1992-08-11 스테이너 브이. 캔스태드 향균성 화합물 및 이의 중간물질의 제조방법
WO1991000923A2 (en) * 1989-07-07 1991-01-24 Schering Corporation Process for producing antibacterial intermediates via enzyme hydrolysis of racemic substrates

Also Published As

Publication number Publication date
DE69220701T2 (de) 1997-11-06
HUT62261A (en) 1993-04-28
NZ242040A (en) 1993-06-25
DE69220701D1 (de) 1997-08-14
CS91292A3 (en) 1992-12-16
CA2064349C (en) 2003-11-25
IL101268A0 (en) 1992-11-15
IL101268A (en) 1997-02-18
EP0507153A2 (de) 1992-10-07
SK282932B6 (sk) 2003-01-09
EP0507153A3 (en) 1993-12-15
KR100250513B1 (ko) 2000-04-01
US5346828A (en) 1994-09-13
CZ289218B6 (cs) 2001-12-12
AU1310692A (en) 1992-10-01
CA2064349A1 (en) 1992-09-28
AU645895B2 (en) 1994-01-27
KR920018012A (ko) 1992-10-21
JP3142627B2 (ja) 2001-03-07
GR3024971T3 (en) 1998-01-30
DK0507153T3 (da) 1997-12-22
ES2106101T3 (es) 1997-11-01
HU214305B (hu) 1998-03-02
HU9201041D0 (en) 1992-06-29
JPH06125790A (ja) 1994-05-10
EP0507153B1 (de) 1997-07-09
IE920866A1 (en) 1992-10-07

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