DE69530499D1 - Racemisierung von levobupivacaine-vorläufern und ihren analogen - Google Patents
Racemisierung von levobupivacaine-vorläufern und ihren analogenInfo
- Publication number
- DE69530499D1 DE69530499D1 DE69530499T DE69530499T DE69530499D1 DE 69530499 D1 DE69530499 D1 DE 69530499D1 DE 69530499 T DE69530499 T DE 69530499T DE 69530499 T DE69530499 T DE 69530499T DE 69530499 D1 DE69530499 D1 DE 69530499D1
- Authority
- DE
- Germany
- Prior art keywords
- acid
- levobupivacaine
- racemization
- analogs
- precursors
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B55/00—Racemisation; Complete or partial inversion
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Peptides Or Proteins (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9420245 | 1994-10-07 | ||
GB9420245A GB9420245D0 (en) | 1994-10-07 | 1994-10-07 | Racemisation |
GBGB9504924.3A GB9504924D0 (en) | 1995-03-10 | 1995-03-10 | Racemisation |
GB9504924 | 1995-03-10 | ||
PCT/GB1995/002383 WO1996011173A2 (en) | 1994-10-07 | 1995-10-09 | Racemisation of precursors to levobupivacaine and analogues thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69530499D1 true DE69530499D1 (de) | 2003-05-28 |
DE69530499T2 DE69530499T2 (de) | 2004-01-08 |
Family
ID=26305756
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69530499T Expired - Lifetime DE69530499T2 (de) | 1994-10-07 | 1995-10-09 | Racemisierung von levobupivacaine-vorläufern und ihren analogen |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP0784603B1 (de) |
JP (1) | JPH11510471A (de) |
AT (1) | ATE238256T1 (de) |
AU (1) | AU695740B2 (de) |
CA (1) | CA2201780C (de) |
DE (1) | DE69530499T2 (de) |
DK (1) | DK0784603T3 (de) |
ES (1) | ES2196081T3 (de) |
MX (1) | MX9702483A (de) |
PT (1) | PT784603E (de) |
WO (1) | WO1996011173A2 (de) |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1963991C3 (de) * | 1969-12-20 | 1975-05-15 | Dynamit Nobel Ag, 5210 Troisdorf | Verfahren zur Gewinnung eines Derivates von L-3,4-dihydroxyphenylalanin |
DE3334849A1 (de) * | 1983-09-27 | 1985-04-04 | Hoechst Ag, 6230 Frankfurt | Verfahren zur racemisierung optisch aktiver aminosaeuren |
GB8421964D0 (en) * | 1984-08-30 | 1984-10-03 | Beecham Group Plc | Chemical process |
DE3435095C2 (de) * | 1984-09-25 | 1986-07-24 | Degussa Ag, 6000 Frankfurt | Verfahren zur Racemisierung von N-Acetyl-D(L)-α-aminocarbonsäuren |
-
1995
- 1995-10-09 AU AU36140/95A patent/AU695740B2/en not_active Ceased
- 1995-10-09 AT AT95933510T patent/ATE238256T1/de not_active IP Right Cessation
- 1995-10-09 CA CA002201780A patent/CA2201780C/en not_active Expired - Fee Related
- 1995-10-09 ES ES95933510T patent/ES2196081T3/es not_active Expired - Lifetime
- 1995-10-09 JP JP8512431A patent/JPH11510471A/ja active Pending
- 1995-10-09 MX MX9702483A patent/MX9702483A/es unknown
- 1995-10-09 DE DE69530499T patent/DE69530499T2/de not_active Expired - Lifetime
- 1995-10-09 PT PT95933510T patent/PT784603E/pt unknown
- 1995-10-09 EP EP95933510A patent/EP0784603B1/de not_active Expired - Lifetime
- 1995-10-09 DK DK95933510T patent/DK0784603T3/da active
- 1995-10-09 WO PCT/GB1995/002383 patent/WO1996011173A2/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
ATE238256T1 (de) | 2003-05-15 |
JPH11510471A (ja) | 1999-09-14 |
CA2201780A1 (en) | 1996-04-18 |
ES2196081T3 (es) | 2003-12-16 |
MX9702483A (es) | 1998-04-30 |
PT784603E (pt) | 2003-08-29 |
EP0784603A2 (de) | 1997-07-23 |
AU3614095A (en) | 1996-05-02 |
DK0784603T3 (da) | 2003-08-18 |
WO1996011173A2 (en) | 1996-04-18 |
AU695740B2 (en) | 1998-08-20 |
CA2201780C (en) | 2007-01-09 |
WO1996011173A3 (en) | 1996-07-04 |
DE69530499T2 (de) | 2004-01-08 |
EP0784603B1 (de) | 2003-04-23 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69525840T2 (de) | Herstellung von arthropodiziden oxadiazinen | |
DE69525950T2 (de) | Racemisierungsverfahren bei der herstellung von levobupivacaine und analogen | |
DE3883495D1 (de) | Enantiomere Derivate von Aminosäure, Verfahren zu deren Herstellung und deren therapeutische Verwendung. | |
FI20000507A (fi) | (+)-1-(3-dimetyyliaminopropyyli)-1-(4'-fluorifenyyli)-1,3-dihydroisobentsofuraani-5-karbonitriili ja sitä sisältävä farmaseuttinen koostumus | |
DE60120570D1 (de) | Bakterium, das befähigt ist L-Glutaminsäure, L-Prolin und L-Arginin herzustellen, und Verfahren zur Herstellung von L-Glutaminsäure, L-Prolin und L-Arginin | |
FI961809A0 (fi) | Uudet (R)-5-karbamoyyli-8-fluori-3-N,N-disubstituoitu-amino 3,4-dihydro-2H-1-bentsopyraanit | |
DE69531624D1 (de) | Verfahren zur herstellung von levobupivacaine und analoge | |
HUP0401887A2 (hu) | Eljárás amlodipin racemát rezolválására | |
DE69716713D1 (de) | Verfahren zur herstellung von d-threo-(r,r)-methylphenidat und recycling nicht erwünschter enantiomere durch epimerisierung | |
ATE417094T1 (de) | Verfahren zur herstellung von l-aminosäure | |
DE69530499D1 (de) | Racemisierung von levobupivacaine-vorläufern und ihren analogen | |
ATE397088T1 (de) | Verfahren zur herstellung von (s)- oder (r)-3,3,3-trifluor-2-hydroxy-2-methylpropionsaü e | |
ATE200889T1 (de) | Verfahren zur herstellung von enantiomerenreiner azetidin-carbonsäure | |
DE59205884D1 (de) | Verfahren zur Herstellung der racemischen und optisch aktiven 1,2,3,4-Tetrahydroisochinolin-3-carbonsäure sowie deren Vorprodukte | |
DE69713163D1 (de) | Verfahren zur herstellung von enantiomerisch angereicherten n-acylazetidin-2-carbonsäuren | |
DE59500920D1 (de) | Verfahren zur Herstellung von 3-Aminomethyl-3,5,5-trimethylcyclohexylamin | |
ATA326986A (de) | Verfahren zur herstellung von neuen optisch aktiven 2-chlor-12-/3-dimethylamino-2-methylpropyl/-12h-dibenzo/d,g//1,3,6/dioxazocinen und saeureadditionssalzen derselben | |
ATE421953T1 (de) | Verfahren zur racemisierung von 1-benzyl-4-(4- fluorophenyl)-3-hydroxymethyl-1,2,3,6- tetrahydropyridin und dessen verwendung in der synthese von paroxetin |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |