ATE238256T1 - Racemisierung von levobupivacaine-vorläufern und ihren analogen - Google Patents

Racemisierung von levobupivacaine-vorläufern und ihren analogen

Info

Publication number
ATE238256T1
ATE238256T1 AT95933510T AT95933510T ATE238256T1 AT E238256 T1 ATE238256 T1 AT E238256T1 AT 95933510 T AT95933510 T AT 95933510T AT 95933510 T AT95933510 T AT 95933510T AT E238256 T1 ATE238256 T1 AT E238256T1
Authority
AT
Austria
Prior art keywords
acid
levobupivacaine
racemization
analogues
precursors
Prior art date
Application number
AT95933510T
Other languages
English (en)
Inventor
Ulrich Conrad Dyer
Raymond Mccague
Martin Woods
Original Assignee
Darwin Discovery Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9420245A external-priority patent/GB9420245D0/en
Priority claimed from GBGB9504924.3A external-priority patent/GB9504924D0/en
Application filed by Darwin Discovery Ltd filed Critical Darwin Discovery Ltd
Application granted granted Critical
Publication of ATE238256T1 publication Critical patent/ATE238256T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B55/00—Racemisation; Complete or partial inversion
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT95933510T 1994-10-07 1995-10-09 Racemisierung von levobupivacaine-vorläufern und ihren analogen ATE238256T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9420245A GB9420245D0 (en) 1994-10-07 1994-10-07 Racemisation
GBGB9504924.3A GB9504924D0 (en) 1995-03-10 1995-03-10 Racemisation
PCT/GB1995/002383 WO1996011173A2 (en) 1994-10-07 1995-10-09 Racemisation of precursors to levobupivacaine and analogues thereof

Publications (1)

Publication Number Publication Date
ATE238256T1 true ATE238256T1 (de) 2003-05-15

Family

ID=26305756

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95933510T ATE238256T1 (de) 1994-10-07 1995-10-09 Racemisierung von levobupivacaine-vorläufern und ihren analogen

Country Status (11)

Country Link
EP (1) EP0784603B1 (de)
JP (1) JPH11510471A (de)
AT (1) ATE238256T1 (de)
AU (1) AU695740B2 (de)
CA (1) CA2201780C (de)
DE (1) DE69530499T2 (de)
DK (1) DK0784603T3 (de)
ES (1) ES2196081T3 (de)
MX (1) MX9702483A (de)
PT (1) PT784603E (de)
WO (1) WO1996011173A2 (de)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1963991C3 (de) * 1969-12-20 1975-05-15 Dynamit Nobel Ag, 5210 Troisdorf Verfahren zur Gewinnung eines Derivates von L-3,4-dihydroxyphenylalanin
DE3334849A1 (de) * 1983-09-27 1985-04-04 Hoechst Ag, 6230 Frankfurt Verfahren zur racemisierung optisch aktiver aminosaeuren
GB8421964D0 (en) * 1984-08-30 1984-10-03 Beecham Group Plc Chemical process
DE3435095C2 (de) * 1984-09-25 1986-07-24 Degussa Ag, 6000 Frankfurt Verfahren zur Racemisierung von N-Acetyl-D(L)-α-aminocarbonsäuren

Also Published As

Publication number Publication date
JPH11510471A (ja) 1999-09-14
CA2201780A1 (en) 1996-04-18
ES2196081T3 (es) 2003-12-16
DE69530499D1 (de) 2003-05-28
MX9702483A (es) 1998-04-30
PT784603E (pt) 2003-08-29
EP0784603A2 (de) 1997-07-23
AU3614095A (en) 1996-05-02
DK0784603T3 (da) 2003-08-18
WO1996011173A2 (en) 1996-04-18
AU695740B2 (en) 1998-08-20
CA2201780C (en) 2007-01-09
WO1996011173A3 (en) 1996-07-04
DE69530499T2 (de) 2004-01-08
EP0784603B1 (de) 2003-04-23

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