PT784603E - Racemizacao de precursores de levobupivacaina e seus analogos - Google Patents

Racemizacao de precursores de levobupivacaina e seus analogos

Info

Publication number
PT784603E
PT784603E PT95933510T PT95933510T PT784603E PT 784603 E PT784603 E PT 784603E PT 95933510 T PT95933510 T PT 95933510T PT 95933510 T PT95933510 T PT 95933510T PT 784603 E PT784603 E PT 784603E
Authority
PT
Portugal
Prior art keywords
preparation
acid
levobupivacaine
analogs
precursors
Prior art date
Application number
PT95933510T
Other languages
English (en)
Inventor
Raymond Mccague
Ulrich Conrad Dyer
Martin Woods
Original Assignee
Darwin Discovery Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9420245A external-priority patent/GB9420245D0/en
Priority claimed from GBGB9504924.3A external-priority patent/GB9504924D0/en
Application filed by Darwin Discovery Ltd filed Critical Darwin Discovery Ltd
Publication of PT784603E publication Critical patent/PT784603E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B55/00Racemisation; Complete or partial inversion
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT95933510T 1994-10-07 1995-10-09 Racemizacao de precursores de levobupivacaina e seus analogos PT784603E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9420245A GB9420245D0 (en) 1994-10-07 1994-10-07 Racemisation
GBGB9504924.3A GB9504924D0 (en) 1995-03-10 1995-03-10 Racemisation

Publications (1)

Publication Number Publication Date
PT784603E true PT784603E (pt) 2003-08-29

Family

ID=26305756

Family Applications (1)

Application Number Title Priority Date Filing Date
PT95933510T PT784603E (pt) 1994-10-07 1995-10-09 Racemizacao de precursores de levobupivacaina e seus analogos

Country Status (11)

Country Link
EP (1) EP0784603B1 (pt)
JP (1) JPH11510471A (pt)
AT (1) ATE238256T1 (pt)
AU (1) AU695740B2 (pt)
CA (1) CA2201780C (pt)
DE (1) DE69530499T2 (pt)
DK (1) DK0784603T3 (pt)
ES (1) ES2196081T3 (pt)
MX (1) MX9702483A (pt)
PT (1) PT784603E (pt)
WO (1) WO1996011173A2 (pt)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1963991C3 (de) * 1969-12-20 1975-05-15 Dynamit Nobel Ag, 5210 Troisdorf Verfahren zur Gewinnung eines Derivates von L-3,4-dihydroxyphenylalanin
DE3334849A1 (de) * 1983-09-27 1985-04-04 Hoechst Ag, 6230 Frankfurt Verfahren zur racemisierung optisch aktiver aminosaeuren
GB8421964D0 (en) * 1984-08-30 1984-10-03 Beecham Group Plc Chemical process
DE3435095C2 (de) * 1984-09-25 1986-07-24 Degussa Ag, 6000 Frankfurt Verfahren zur Racemisierung von N-Acetyl-D(L)-α-aminocarbonsäuren

Also Published As

Publication number Publication date
MX9702483A (es) 1998-04-30
EP0784603B1 (en) 2003-04-23
WO1996011173A3 (en) 1996-07-04
CA2201780C (en) 2007-01-09
DK0784603T3 (da) 2003-08-18
EP0784603A2 (en) 1997-07-23
WO1996011173A2 (en) 1996-04-18
ES2196081T3 (es) 2003-12-16
JPH11510471A (ja) 1999-09-14
DE69530499T2 (de) 2004-01-08
AU3614095A (en) 1996-05-02
CA2201780A1 (en) 1996-04-18
AU695740B2 (en) 1998-08-20
DE69530499D1 (de) 2003-05-28
ATE238256T1 (de) 2003-05-15

Similar Documents

Publication Publication Date Title
PT756594E (pt) Preparacao de oxadiazinas artropodicidas
DE3883495D1 (de) Enantiomere Derivate von Aminosäure, Verfahren zu deren Herstellung und deren therapeutische Verwendung.
DE69525950T2 (de) Racemisierungsverfahren bei der herstellung von levobupivacaine und analogen
DE69521175T2 (de) Verfahren zur Herstellung von Xanthangummi
DE69004582D1 (de) Verfahren zur Herstellung von alpha-Hydroxycarbonsäure-Amid.
PT784603E (pt) Racemizacao de precursores de levobupivacaina e seus analogos
ATE397088T1 (de) Verfahren zur herstellung von (s)- oder (r)-3,3,3-trifluor-2-hydroxy-2-methylpropionsaü e
DE59205884D1 (de) Verfahren zur Herstellung der racemischen und optisch aktiven 1,2,3,4-Tetrahydroisochinolin-3-carbonsäure sowie deren Vorprodukte
ATE118470T1 (de) Isolierung von l-phenylalanin aus dessen racemischen mischungen.
DE59500920D1 (de) Verfahren zur Herstellung von 3-Aminomethyl-3,5,5-trimethylcyclohexylamin
NO990159L (no) FremgangsmÕte for fremstilling av enantiomerisk anrikede N-acylazetidin-2-karboksylsyrer
DE59812284D1 (de) Verfahren zur Herstellung von 4-Amino-2,2,6,6-tetramethyl-piperidin
ATA326986A (de) Verfahren zur herstellung von neuen optisch aktiven 2-chlor-12-/3-dimethylamino-2-methylpropyl/-12h-dibenzo/d,g//1,3,6/dioxazocinen und saeureadditionssalzen derselben
ES8504725A1 (es) Procedimiento para preparar los antipodas opticos de 8-amino-2-metil-4-fenil-1, 2, 3, 4-tetrahidroisoquinoleina
ATE421953T1 (de) Verfahren zur racemisierung von 1-benzyl-4-(4- fluorophenyl)-3-hydroxymethyl-1,2,3,6- tetrahydropyridin und dessen verwendung in der synthese von paroxetin
ATE65091T1 (de) Kontinuierliches verfahren zur enzymatischen herstellung von isomaltulose.