IL101268A - Stereoisomeric enrichment of 2-amino-3-hydroxy-3-phenylpropionic acids - Google Patents

Stereoisomeric enrichment of 2-amino-3-hydroxy-3-phenylpropionic acids

Info

Publication number
IL101268A
IL101268A IL10126892A IL10126892A IL101268A IL 101268 A IL101268 A IL 101268A IL 10126892 A IL10126892 A IL 10126892A IL 10126892 A IL10126892 A IL 10126892A IL 101268 A IL101268 A IL 101268A
Authority
IL
Israel
Prior art keywords
amino
hydroxy
threo
phenylpropionic acids
stereoisomeric enrichment
Prior art date
Application number
IL10126892A
Other languages
English (en)
Other versions
IL101268A0 (en
Original Assignee
Celgene Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27418304&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL101268(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Celgene Corp filed Critical Celgene Corp
Publication of IL101268A0 publication Critical patent/IL101268A0/xx
Publication of IL101268A publication Critical patent/IL101268A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00—Preparation of sulfones; Preparation of sulfoxides
    • C07C315/06—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/26—Separation; Purification; Stabilisation; Use of additives
    • C07C319/28—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P11/00—Preparation of sulfur-containing organic compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/829—Alcaligenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL10126892A 1991-03-27 1992-03-18 Stereoisomeric enrichment of 2-amino-3-hydroxy-3-phenylpropionic acids IL101268A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US67610291A 1991-03-27 1991-03-27
US68930091A 1991-04-22 1991-04-22
US07/844,724 US5346828A (en) 1991-03-27 1992-03-02 Stereoisomeric enrichment of 2-amino-3-hydroxy-3-phenylpropionic acids using d-threonine aldolase

Publications (2)

Publication Number Publication Date
IL101268A0 IL101268A0 (en) 1992-11-15
IL101268A true IL101268A (en) 1997-02-18

Family

ID=27418304

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10126892A IL101268A (en) 1991-03-27 1992-03-18 Stereoisomeric enrichment of 2-amino-3-hydroxy-3-phenylpropionic acids

Country Status (17)

Country Link
US (1) US5346828A (de)
EP (1) EP0507153B1 (de)
JP (1) JP3142627B2 (de)
KR (1) KR100250513B1 (de)
AT (1) ATE155175T1 (de)
AU (1) AU645895B2 (de)
CA (1) CA2064349C (de)
CZ (1) CZ289218B6 (de)
DE (1) DE69220701T2 (de)
DK (1) DK0507153T3 (de)
ES (1) ES2106101T3 (de)
GR (1) GR3024971T3 (de)
HU (1) HU214305B (de)
IE (1) IE920866A1 (de)
IL (1) IL101268A (de)
NZ (1) NZ242040A (de)
SK (1) SK282932B6 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW397866B (en) 1993-07-14 2000-07-11 Bristol Myers Squibb Co Enzymatic processes for the resolution of enantiomeric mixtures of compounds useful as intermediates in the preparation of taxanes
JPH09506610A (ja) * 1993-12-17 1997-06-30 ディーエスエム エヌ．ブイ． フェニルセリンアミド、及びフェニルセリン／フェニルセリンアミド の調製
US7172885B2 (en) * 2004-12-10 2007-02-06 Cambrex North Brunswick, Inc. Thermostable omega-transaminases
EP1882737B1 (de) * 2005-05-20 2011-09-14 Ajinomoto Co., Inc. Verfahren zur herstellung eines l-serin-derivats und bei dem verfahren verwendetes enzym
US7518017B2 (en) 2006-02-17 2009-04-14 Idexx Laboratories Fenicol compounds and methods synthesizing 2-trifluoroacetamido-3-substituted propiophenone compounds
KR100758512B1 (ko) 2006-07-20 2007-09-14 엔자이텍 주식회사 효소적 방법에 의한 광학활성3-히드록시-3-페닐프로피온산과 광학활성3-아실옥시-3-페닐프로피온산의 제조 방법
SG172891A1 (en) 2009-01-08 2011-08-29 Codexis Inc Transaminase polypeptides
WO2010099501A2 (en) 2009-02-26 2010-09-02 Codexis, Inc. Transaminase biocatalysts
CN102597226B (zh) 2009-06-22 2015-08-19 科德克希思公司 转氨酶反应
US8852900B2 (en) 2010-06-17 2014-10-07 Codexis, Inc. Biocatalysts and methods for the synthesis of (S)-3-(1-aminoethyl)-phenol
EP2606139B1 (de) 2010-08-16 2015-07-15 Codexis, Inc. Biokatalysatoren und verfahren zur synthese von (1r,2r)-2-(3,4-dimethoxyphenethoxy-)cyclohexanamin
CN101941927B (zh) * 2010-09-28 2012-10-03 湖北美天生物科技有限公司 氟苯尼考中间体(1r,2r)-2-氨基-1–(4-(甲砜基)苯基)-1,3-丙二醇的合成方法
CN115611785B (zh) * 2022-12-19 2023-03-14 天津工微生物科技有限公司 (2r,3s)-2-氨基-3-羟基-3-(4-(甲基磺酰基)苯基)丙酸的纯化方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3733352A (en) * 1969-07-29 1973-05-15 Sumitomo Chemical Co Preparation of d-threo-1-p-methyl-sulfonylphenyl-2-dichloro-acet-amidopropane-1,3-diol
US3871958A (en) * 1972-03-04 1975-03-18 Ajinomoto Kk Biological method of producing serine and serinol derivatives
FR2378746A1 (fr) 1977-01-28 1978-08-25 Synthelabo Derives d'acides a-amines
US4235892A (en) * 1979-02-05 1980-11-25 Schering Corporation, Patent Dept. 1-Aryl-2-acylamido-3-fluoro-1-propanols, methods for their use as antibacterial agents and compositions useful therefor
US4492757A (en) * 1981-12-28 1985-01-08 Denki Kagaku Kogyo Kabushiki Kaisha Process for preparing L-threonine
US4582918A (en) * 1984-09-19 1986-04-15 Schering Corporation Preparation of intermediates for (threo)-1-aryl-2-acylamido-3-fluoro-1-propanols
US4677214A (en) * 1984-09-19 1987-06-30 Schering Corporation Intermediates for preparation of (threo)-1-aryl-2-acylamido-3-fluoro-1-propanols
DE3543021A1 (de) * 1985-12-05 1987-06-11 Boehringer Mannheim Gmbh Verbesserte verfahren zur herstellung von d-threo-1-(p-methylsulfonylphenyl) -2-dichloracetamido-propandiol-1,3-(thiamphenicol) sowie verwendung geeigneter zwischenprodukte
EP0405104A1 (de) * 1989-05-15 1991-01-02 Schering Corporation Verfahren zur Herstellung antibakterieller Verbindungen und Intermediate hierzu
WO1991000923A2 (en) * 1989-07-07 1991-01-24 Schering Corporation Process for producing antibacterial intermediates via enzyme hydrolysis of racemic substrates

Also Published As

Publication number Publication date
KR920018012A (ko) 1992-10-21
HU214305B (hu) 1998-03-02
JP3142627B2 (ja) 2001-03-07
IE920866A1 (en) 1992-10-07
AU645895B2 (en) 1994-01-27
NZ242040A (en) 1993-06-25
JPH06125790A (ja) 1994-05-10
CS91292A3 (en) 1992-12-16
ATE155175T1 (de) 1997-07-15
AU1310692A (en) 1992-10-01
IL101268A0 (en) 1992-11-15
KR100250513B1 (ko) 2000-04-01
ES2106101T3 (es) 1997-11-01
CZ289218B6 (cs) 2001-12-12
US5346828A (en) 1994-09-13
SK282932B6 (sk) 2003-01-09
GR3024971T3 (en) 1998-01-30
EP0507153B1 (de) 1997-07-09
EP0507153A3 (en) 1993-12-15
HUT62261A (en) 1993-04-28
DK0507153T3 (da) 1997-12-22
CA2064349C (en) 2003-11-25
EP0507153A2 (de) 1992-10-07
HU9201041D0 (en) 1992-06-29
CA2064349A1 (en) 1992-09-28
DE69220701D1 (de) 1997-08-14
DE69220701T2 (de) 1997-11-06

Similar Documents

Publication Publication Date Title
EP0507153A3 (en) Stereoisomeric enrichment of 2-amino-3-hydroxy-3-phenyl-propionic acids
AU628183B2 (en) Enantiomeric enrichment and stereoselective synthesis of chiral amines
ATE417094T1 (de) Verfahren zur herstellung von l-aminosäure
ATE65491T1 (de) Verfahren zur herstellung von hochreinem 4,6diamino-1,3-benzoldiol.
EP0373597A3 (de) Gen und Genstruktur, codierend für eine Aminotransferase, und Mikroorganismen, die dieses Gen exprimieren
DK440985A (da) Enzymatisk proces
JPS6486898A (en) Method for manufacturing ibuprofen
DE3650351D1 (de) Biokatalytisches Verfahren zur Herstellung phenolischer Harze.
FI912482A0 (fi) Metod foer separering av organiska substanser.
ATE212626T1 (de) Verfahren zur herstellung trockener thioctsäure
DE3878264D1 (de) Monoacetylierung von diolen mit einem biokatalysator aus corynebakteriumoxidans.
AU573261B2 (en) Preparation of tert-leucine
SE9404211D0 (sv) Förfarande för anriktning av hartssyror ur lövvedhaltig sulfatsåpa
ATE144285T1 (de) Mikrobiologisches verfahren zur herstellung von 5-hydroxy-2-pyrazincarbonsäure
HUT40993A (en) Process for production of esthers of o /2,6-dichlorphenilamino/-phenil-acetic acid
ATE83768T1 (de) Verfahren zur herstellung von crotonobetainhydrochlorid.
JPS575691A (en) Production of l-valine through fermentation process
ZA891246B (en) The production of formic acid from a nitrogenous base,carbon dioxide and hydrogen
HUT40988A (en) Process for production of optically clean enantiomer of cis-2,2-dimethyl-3/2,2-dihalogen-vinil/-cycloprophan carbonic acid
SE8401109L (sv) Stolpe bestaende av tva delar
HUT44271A (en) Process for production of 7-alfa-acetil-thio-steroids

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
RH Patent void
KB Patent renewed
KB Patent renewed
EXP Patent expired