ATE154011T1 - Inhibitoren der calciumaufnahme - Google Patents
Inhibitoren der calciumaufnahmeInfo
- Publication number
- ATE154011T1 ATE154011T1 AT91115932T AT91115932T ATE154011T1 AT E154011 T1 ATE154011 T1 AT E154011T1 AT 91115932 T AT91115932 T AT 91115932T AT 91115932 T AT91115932 T AT 91115932T AT E154011 T1 ATE154011 T1 AT E154011T1
- Authority
- AT
- Austria
- Prior art keywords
- inhibitors
- calcium absorption
- thrombocytes
- propene
- leukocytes
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
- C07D213/08—Preparation by ring-closure
- C07D213/09—Preparation by ring-closure involving the use of ammonia, amines, amine salts, or nitriles
- C07D213/10—Preparation by ring-closure involving the use of ammonia, amines, amine salts, or nitriles from acetaldehyde or cyclic polymers thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
- C07D213/50—Ketonic radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Reproductive Health (AREA)
- Transplantation (AREA)
- Dermatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Hydrogenated Pyridines (AREA)
- Cosmetics (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US58541290A | 1990-09-20 | 1990-09-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE154011T1 true ATE154011T1 (de) | 1997-06-15 |
Family
ID=24341317
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT91115932T ATE154011T1 (de) | 1990-09-20 | 1991-09-19 | Inhibitoren der calciumaufnahme |
Country Status (19)
Country | Link |
---|---|
US (1) | US5500429A (de) |
EP (1) | EP0476646B1 (de) |
JP (1) | JP3031766B2 (de) |
KR (1) | KR100198040B1 (de) |
CN (1) | CN1063685A (de) |
AT (1) | ATE154011T1 (de) |
AU (1) | AU653957B2 (de) |
CA (1) | CA2051494C (de) |
DE (1) | DE69126392T2 (de) |
ES (1) | ES2106042T3 (de) |
FI (1) | FI914409A (de) |
HU (1) | HUT59099A (de) |
IE (1) | IE913300A1 (de) |
IL (1) | IL99515A0 (de) |
NO (1) | NO913684L (de) |
NZ (1) | NZ239864A (de) |
PT (1) | PT99011A (de) |
TW (1) | TW205548B (de) |
ZA (1) | ZA917371B (de) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU640523B2 (en) * | 1990-09-20 | 1993-08-26 | Merrell Dow Pharmaceuticals Inc. | 1-phenyl-3-aryl-2-propyne-1-ones |
KR0130883Y1 (ko) * | 1994-02-02 | 1998-12-15 | 김광호 | 컴퓨터의 하드 디스크 드라이버 착탈장치 |
EP1632281B1 (de) | 2003-12-15 | 2011-09-14 | Rohm And Haas Company | Verfahren zum Absorbieren von hydrophoben Substanzen auf Polymere mit hohler Struktur |
WO2006010379A1 (en) | 2004-07-29 | 2006-02-02 | Actelion Pharmaceuticals Ltd. | Novel thiophene derivatives as immunosuppressive agents |
NZ562562A (en) | 2005-03-23 | 2010-11-26 | Actelion Pharmaceuticals Ltd | Hydrogenated benzo(C)thiophene derivatives as immunomodulators |
BRPI0609665A2 (pt) | 2005-03-23 | 2010-04-20 | Actelion Pharmaceuticals Ltd | composto, composição farmacêutica, e, uso de um composto |
JP2008546758A (ja) | 2005-06-24 | 2008-12-25 | アクテリオン ファーマシューティカルズ リミテッド | 新規チオフェン誘導体 |
KR100779610B1 (ko) * | 2005-09-13 | 2007-11-28 | 영남대학교 산학협력단 | 1-퓨란-2-일-3-피리딘-2-일-프로페논을 함유하는혈관신생으로 인한 질환 및 암질환의 예방 또는 치료용약학조성물 |
WO2007032591A1 (en) * | 2005-09-13 | 2007-03-22 | Industry-Academic Cooperation Foundation, Yeungnam University | Composition comprising 1-furan-2-yl-3-pyridin-2-yl-pr0pen0ne having anti-angiogenic activity and cancer growth inhibitory activity |
AR057894A1 (es) | 2005-11-23 | 2007-12-26 | Actelion Pharmaceuticals Ltd | Derivados de tiofeno |
EP1979345B1 (de) * | 2006-01-24 | 2009-11-04 | Actelion Pharmaceuticals Ltd. | Neue pyrinderivate |
CL2007002593A1 (es) | 2006-09-07 | 2008-06-13 | Actelion Pharmaceuticals Ltd | Compuestos derivados de 4-heteroaril-piridina; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como rechazo de organos transplantados, sindromes autoinmunes y cancer. |
AR061841A1 (es) | 2006-09-07 | 2008-09-24 | Actelion Pharmaceuticals Ltd | Derivados de tiofen-oxadiazoles, agonistas del receptor s1p1/edg1, composiciones farmaceuticas que los contienen y usos como agentes inmunomoduladores. |
KR101454937B1 (ko) | 2006-09-08 | 2014-10-27 | 액테리온 파마슈티칼 리미티드 | 면역조절제로서 피리딘-3-일 유도체 |
NZ580454A (en) | 2007-03-16 | 2011-05-27 | Actelion Pharmaceuticals Ltd | Amino- pyridine derivatives as s1p1 /edg1 receptor agonists |
NZ588438A (en) | 2008-03-07 | 2012-05-25 | Actelion Pharmaceuticals Ltd | Pyridin-2-yl oxadiazole derivatives as immunomodulating agents |
KR101409131B1 (ko) | 2009-07-16 | 2014-06-17 | 액테리온 파마슈티칼 리미티드 | 피리딘-4-일 유도체 |
US20130079348A1 (en) * | 2010-03-03 | 2013-03-28 | Calcimedica, Inc. | Compounds that modulate intracellular calcium |
AR084883A1 (es) | 2011-01-19 | 2013-07-10 | Actelion Pharmaceuticals Ltd | Derivados de 2-metoxi-piridin-4-ilo |
JP2014100171A (ja) * | 2012-11-16 | 2014-06-05 | Hayashi Bussan Co Ltd | 商品落下防止具 |
CN107667104B (zh) | 2015-05-20 | 2022-03-22 | 爱杜西亚药品有限公司 | (s)-3-{4-[5-(2-环戊基-6-甲氧基-吡啶-4-基)-[1,2,4]噁二唑-3-基]-2-乙基-6-甲基-苯氧基}-丙烷-1,2-二醇的结晶形式 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3409424A (en) * | 1966-03-01 | 1968-11-05 | Ethyl Corp | Propynones as defoliants |
FR2081591A1 (en) * | 1970-03-27 | 1971-12-10 | Unicler | 2, 4-dimethoxyphenyl beta-pyrid-4-ylvinyl ketone - for treating capillary fragility and permeability |
BE789099A (fr) * | 1971-09-22 | 1973-03-21 | Boehringer Sohn Ingelheim | Nouveaux derives de la pyridine et procede pour les fabriquer |
FR2387956A1 (fr) * | 1977-04-20 | 1978-11-17 | Unicler | Derives de la pyridine et leur preparation |
US4582836A (en) * | 1985-01-09 | 1986-04-15 | Mcneilab, Inc. | Octahydroindolizine compounds useful as analgesics |
DK49688A (da) * | 1987-03-20 | 1988-09-21 | Hoffmann La Roche | Propiolophenonderivater |
-
1991
- 1991-09-16 CA CA002051494A patent/CA2051494C/en not_active Expired - Lifetime
- 1991-09-16 AU AU84529/91A patent/AU653957B2/en not_active Ceased
- 1991-09-16 ZA ZA917371A patent/ZA917371B/xx unknown
- 1991-09-17 TW TW080107366A patent/TW205548B/zh active
- 1991-09-17 IL IL99515A patent/IL99515A0/xx unknown
- 1991-09-18 CN CN91109004A patent/CN1063685A/zh active Pending
- 1991-09-19 AT AT91115932T patent/ATE154011T1/de not_active IP Right Cessation
- 1991-09-19 HU HU913010A patent/HUT59099A/hu unknown
- 1991-09-19 IE IE330091A patent/IE913300A1/en unknown
- 1991-09-19 PT PT99011A patent/PT99011A/pt not_active Application Discontinuation
- 1991-09-19 ES ES91115932T patent/ES2106042T3/es not_active Expired - Lifetime
- 1991-09-19 DE DE69126392T patent/DE69126392T2/de not_active Expired - Lifetime
- 1991-09-19 NO NO91913684A patent/NO913684L/no unknown
- 1991-09-19 EP EP91115932A patent/EP0476646B1/de not_active Expired - Lifetime
- 1991-09-19 FI FI914409A patent/FI914409A/fi unknown
- 1991-09-19 NZ NZ239864A patent/NZ239864A/en unknown
- 1991-09-20 KR KR1019910016526A patent/KR100198040B1/ko not_active IP Right Cessation
- 1991-09-20 JP JP3268508A patent/JP3031766B2/ja not_active Expired - Lifetime
-
1993
- 1993-11-17 US US08/154,146 patent/US5500429A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AU653957B2 (en) | 1994-10-20 |
JP3031766B2 (ja) | 2000-04-10 |
NO913684D0 (no) | 1991-09-19 |
FI914409A (fi) | 1992-03-21 |
IL99515A0 (en) | 1992-08-18 |
NO913684L (no) | 1992-03-23 |
EP0476646B1 (de) | 1997-06-04 |
FI914409A0 (fi) | 1991-09-19 |
TW205548B (de) | 1993-05-11 |
CN1063685A (zh) | 1992-08-19 |
JPH06271540A (ja) | 1994-09-27 |
KR920006316A (ko) | 1992-04-27 |
US5500429A (en) | 1996-03-19 |
HUT59099A (en) | 1992-04-28 |
CA2051494A1 (en) | 1992-03-21 |
DE69126392D1 (de) | 1997-07-10 |
ZA917371B (en) | 1992-06-24 |
AU8452991A (en) | 1992-03-26 |
IE913300A1 (en) | 1992-02-25 |
HU913010D0 (en) | 1992-01-28 |
ES2106042T3 (es) | 1997-11-01 |
PT99011A (pt) | 1992-08-31 |
EP0476646A1 (de) | 1992-03-25 |
NZ239864A (en) | 1994-05-26 |
CA2051494C (en) | 2006-03-14 |
KR100198040B1 (ko) | 1999-06-15 |
DE69126392T2 (de) | 1998-01-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69126392D1 (de) | Inhibitoren der Calciumaufnahme | |
MX9203370A (es) | Desulfatohirudina y composiciones farmaceuticas que la contienen. | |
SE8404065D0 (sv) | Novel biologically active compounds | |
SE8600658D0 (sv) | Novel composition of matter | |
NO913683L (no) | Fremgangsmaate for fremstilling av kalsiumopptaksinhibitorer. | |
DE69112747T2 (de) | Inhibitoren der Calciumaufnahme. | |
ITMI912738A1 (it) | Complessi del ferro con la conalbumina e i suoi derivati | |
DK576887A (da) | Farmaceutiske midler | |
DE59407576D1 (de) | Verwendung von Etofibrat und pharmazeutische Zusammensetzungen, enthaltend Etofibrat, zur Behandlung der diabetischen Angio- und Retinopathie |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |