ATE146472T1 - Umwandlungsverfahren von lorabef dihydrate in loracarbef monohydrate - Google Patents
Umwandlungsverfahren von lorabef dihydrate in loracarbef monohydrateInfo
- Publication number
- ATE146472T1 ATE146472T1 AT94303945T AT94303945T ATE146472T1 AT E146472 T1 ATE146472 T1 AT E146472T1 AT 94303945 T AT94303945 T AT 94303945T AT 94303945 T AT94303945 T AT 94303945T AT E146472 T1 ATE146472 T1 AT E146472T1
- Authority
- AT
- Austria
- Prior art keywords
- dihydrate
- lorabef
- conversion process
- loracarbef monohydrate
- monohydrate
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
- C07D463/16—Nitrogen atoms
- C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
- C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/071,550 US5374719A (en) | 1993-06-04 | 1993-06-04 | Process for converting loracarbef dihydrate to loracarbef monohydrate |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE146472T1 true ATE146472T1 (de) | 1997-01-15 |
Family
ID=22102051
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT94303945T ATE146472T1 (de) | 1993-06-04 | 1994-06-01 | Umwandlungsverfahren von lorabef dihydrate in loracarbef monohydrate |
Country Status (29)
Country | Link |
---|---|
US (1) | US5374719A (de) |
EP (1) | EP0627430B1 (de) |
JP (1) | JP3442479B2 (de) |
KR (1) | KR100311699B1 (de) |
CN (1) | CN1042424C (de) |
AT (1) | ATE146472T1 (de) |
AU (1) | AU678000B2 (de) |
BR (1) | BR9402149A (de) |
CA (1) | CA2125001C (de) |
CO (1) | CO4230100A1 (de) |
CZ (1) | CZ283468B6 (de) |
DE (1) | DE69401163T2 (de) |
DK (1) | DK0627430T3 (de) |
ES (1) | ES2097002T3 (de) |
FI (1) | FI108132B (de) |
GR (1) | GR3022111T3 (de) |
HU (1) | HU217066B (de) |
IL (1) | IL109871A (de) |
MY (1) | MY110724A (de) |
NO (1) | NO306302B1 (de) |
NZ (1) | NZ260653A (de) |
PE (1) | PE13195A1 (de) |
PH (1) | PH30304A (de) |
PL (1) | PL174539B1 (de) |
RU (1) | RU2124013C1 (de) |
TW (1) | TW252980B (de) |
UA (1) | UA27812C2 (de) |
YU (1) | YU33394A (de) |
ZA (1) | ZA943827B (de) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5550231A (en) * | 1993-06-15 | 1996-08-27 | Eli Lilly And Company | Loracarbef hydrochloride C1-C3 alcohol solvates and uses thereof |
US5580977A (en) * | 1995-03-01 | 1996-12-03 | Eli Lilly And Company | Process for preparing loracarbef monohydrate |
US20070225285A1 (en) * | 2005-11-04 | 2007-09-27 | Amira Pharmaceuticals, Inc. | 5-lipoxygenase-activating protein (flap) inhibitors |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3502663A (en) * | 1969-04-21 | 1970-03-24 | Lilly Co Eli | Crystalline cephalosporin,method for its manufacture |
US3531481A (en) * | 1969-04-21 | 1970-09-29 | Lilly Co Eli | Method for manufacture of crystalline cephalosporin |
ZA887409B (en) * | 1987-10-06 | 1990-06-27 | Lilly Co Eli | Crystalline beta-lactam hydrate |
CA2002596A1 (en) * | 1988-11-14 | 1990-05-14 | Thomas M. Eckrich | Hydrates of b-lactam antibiotic |
US4977257A (en) * | 1988-11-14 | 1990-12-11 | Eli Lilly And Company | DMF solvates of a β-lactam antibiotic |
-
1993
- 1993-06-04 US US08/071,550 patent/US5374719A/en not_active Expired - Lifetime
-
1994
- 1994-06-01 DK DK94303945.3T patent/DK0627430T3/da active
- 1994-06-01 AT AT94303945T patent/ATE146472T1/de not_active IP Right Cessation
- 1994-06-01 ZA ZA943827A patent/ZA943827B/xx unknown
- 1994-06-01 PL PL94303676A patent/PL174539B1/pl not_active IP Right Cessation
- 1994-06-01 TW TW083105006A patent/TW252980B/zh active
- 1994-06-01 NZ NZ260653A patent/NZ260653A/en unknown
- 1994-06-01 ES ES94303945T patent/ES2097002T3/es not_active Expired - Lifetime
- 1994-06-01 EP EP94303945A patent/EP0627430B1/de not_active Expired - Lifetime
- 1994-06-01 CZ CZ941342A patent/CZ283468B6/cs not_active IP Right Cessation
- 1994-06-01 PE PE1994243644A patent/PE13195A1/es not_active Application Discontinuation
- 1994-06-01 DE DE69401163T patent/DE69401163T2/de not_active Expired - Fee Related
- 1994-06-01 BR BR9402149A patent/BR9402149A/pt not_active Application Discontinuation
- 1994-06-02 PH PH48386A patent/PH30304A/en unknown
- 1994-06-02 KR KR1019940012340A patent/KR100311699B1/ko not_active IP Right Cessation
- 1994-06-02 AU AU64516/94A patent/AU678000B2/en not_active Ceased
- 1994-06-02 CA CA002125001A patent/CA2125001C/en not_active Expired - Fee Related
- 1994-06-02 IL IL10987194A patent/IL109871A/en not_active IP Right Cessation
- 1994-06-02 NO NO942048A patent/NO306302B1/no not_active IP Right Cessation
- 1994-06-02 CO CO94023737A patent/CO4230100A1/es unknown
- 1994-06-02 UA UA94005241A patent/UA27812C2/uk unknown
- 1994-06-02 MY MYPI94001408A patent/MY110724A/en unknown
- 1994-06-03 YU YU33394A patent/YU33394A/sh unknown
- 1994-06-03 JP JP12228394A patent/JP3442479B2/ja not_active Expired - Fee Related
- 1994-06-03 FI FI942633A patent/FI108132B/fi not_active IP Right Cessation
- 1994-06-03 HU HU9401675A patent/HU217066B/hu not_active IP Right Cessation
- 1994-06-03 RU RU94019424A patent/RU2124013C1/ru not_active IP Right Cessation
- 1994-06-03 CN CN94106984A patent/CN1042424C/zh not_active Expired - Fee Related
-
1996
- 1996-12-19 GR GR960403422T patent/GR3022111T3/el unknown
Also Published As
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ATE146472T1 (de) | Umwandlungsverfahren von lorabef dihydrate in loracarbef monohydrate | |
ATE178328T1 (de) | Loracarbef isopropanolat und umwandlungsverfahren vom isopropanolat in loracarbef monohydrat |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |