NO306302B1 - FremgangsmÕte for fremstilling av krystallinsk loracarbef-monohydrat - Google Patents

FremgangsmÕte for fremstilling av krystallinsk loracarbef-monohydrat

Info

Publication number
NO306302B1
NO306302B1 NO942048A NO942048A NO306302B1 NO 306302 B1 NO306302 B1 NO 306302B1 NO 942048 A NO942048 A NO 942048A NO 942048 A NO942048 A NO 942048A NO 306302 B1 NO306302 B1 NO 306302B1
Authority
NO
Norway
Prior art keywords
preparation
crystalline
loracarbef monohydrate
crystalline loracarbef
monohydrate
Prior art date
Application number
NO942048A
Other languages
English (en)
Other versions
NO942048L (no
NO942048D0 (no
Inventor
Edward Francis Plocharczyk
Erin Eckert Strouse
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of NO942048D0 publication Critical patent/NO942048D0/no
Publication of NO942048L publication Critical patent/NO942048L/no
Publication of NO306302B1 publication Critical patent/NO306302B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
    • C07D463/16—Nitrogen atoms
    • C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
    • C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
NO942048A 1993-06-04 1994-06-02 FremgangsmÕte for fremstilling av krystallinsk loracarbef-monohydrat NO306302B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/071,550 US5374719A (en) 1993-06-04 1993-06-04 Process for converting loracarbef dihydrate to loracarbef monohydrate

Publications (3)

Publication Number Publication Date
NO942048D0 NO942048D0 (no) 1994-06-02
NO942048L NO942048L (no) 1994-12-05
NO306302B1 true NO306302B1 (no) 1999-10-18

Family

ID=22102051

Family Applications (1)

Application Number Title Priority Date Filing Date
NO942048A NO306302B1 (no) 1993-06-04 1994-06-02 FremgangsmÕte for fremstilling av krystallinsk loracarbef-monohydrat

Country Status (29)

Country Link
US (1) US5374719A (no)
EP (1) EP0627430B1 (no)
JP (1) JP3442479B2 (no)
KR (1) KR100311699B1 (no)
CN (1) CN1042424C (no)
AT (1) ATE146472T1 (no)
AU (1) AU678000B2 (no)
BR (1) BR9402149A (no)
CA (1) CA2125001C (no)
CO (1) CO4230100A1 (no)
CZ (1) CZ283468B6 (no)
DE (1) DE69401163T2 (no)
DK (1) DK0627430T3 (no)
ES (1) ES2097002T3 (no)
FI (1) FI108132B (no)
GR (1) GR3022111T3 (no)
HU (1) HU217066B (no)
IL (1) IL109871A (no)
MY (1) MY110724A (no)
NO (1) NO306302B1 (no)
NZ (1) NZ260653A (no)
PE (1) PE13195A1 (no)
PH (1) PH30304A (no)
PL (1) PL174539B1 (no)
RU (1) RU2124013C1 (no)
TW (1) TW252980B (no)
UA (1) UA27812C2 (no)
YU (1) YU33394A (no)
ZA (1) ZA943827B (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5550231A (en) * 1993-06-15 1996-08-27 Eli Lilly And Company Loracarbef hydrochloride C1-C3 alcohol solvates and uses thereof
US5580977A (en) * 1995-03-01 1996-12-03 Eli Lilly And Company Process for preparing loracarbef monohydrate
US20070225285A1 (en) * 2005-11-04 2007-09-27 Amira Pharmaceuticals, Inc. 5-lipoxygenase-activating protein (flap) inhibitors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3502663A (en) * 1969-04-21 1970-03-24 Lilly Co Eli Crystalline cephalosporin,method for its manufacture
US3531481A (en) * 1969-04-21 1970-09-29 Lilly Co Eli Method for manufacture of crystalline cephalosporin
ZA887409B (en) * 1987-10-06 1990-06-27 Lilly Co Eli Crystalline beta-lactam hydrate
US4977257A (en) * 1988-11-14 1990-12-11 Eli Lilly And Company DMF solvates of a β-lactam antibiotic
CA2002596A1 (en) * 1988-11-14 1990-05-14 Thomas M. Eckrich Hydrates of b-lactam antibiotic

Also Published As

Publication number Publication date
PL303676A1 (en) 1994-12-12
AU6451694A (en) 1994-12-08
CN1042424C (zh) 1999-03-10
CO4230100A1 (es) 1995-10-19
ZA943827B (en) 1995-12-01
FI108132B (fi) 2001-11-30
DE69401163D1 (de) 1997-01-30
GR3022111T3 (en) 1997-03-31
US5374719A (en) 1994-12-20
DK0627430T3 (da) 1997-06-02
BR9402149A (pt) 1994-12-27
YU33394A (sh) 1996-10-18
CA2125001C (en) 2004-08-03
CZ283468B6 (cs) 1998-04-15
NO942048L (no) 1994-12-05
NZ260653A (en) 1995-12-21
UA27812C2 (uk) 2000-10-16
DE69401163T2 (de) 1997-04-30
PE13195A1 (es) 1995-05-24
PL174539B1 (pl) 1998-08-31
HU9401675D0 (en) 1994-09-28
CN1097754A (zh) 1995-01-25
RU2124013C1 (ru) 1998-12-27
EP0627430A1 (en) 1994-12-07
AU678000B2 (en) 1997-05-15
FI942633A0 (fi) 1994-06-03
HU217066B (hu) 1999-11-29
TW252980B (no) 1995-08-01
NO942048D0 (no) 1994-06-02
KR100311699B1 (ko) 2001-12-28
KR950000701A (ko) 1995-01-03
IL109871A0 (en) 1994-10-07
JP3442479B2 (ja) 2003-09-02
FI942633A (fi) 1994-12-05
EP0627430B1 (en) 1996-12-18
IL109871A (en) 1998-08-16
HUT67743A (en) 1995-04-28
MY110724A (en) 1999-01-30
CZ134294A3 (en) 1994-12-15
CA2125001A1 (en) 1994-12-05
PH30304A (en) 1997-02-20
RU94019424A (ru) 1996-04-20
ES2097002T3 (es) 1997-03-16
ATE146472T1 (de) 1997-01-15
JPH06345763A (ja) 1994-12-20

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Legal Events

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MM1K Lapsed by not paying the annual fees