ATE136221T1 - Osteo-induktive pharmazeutische formulierungen - Google Patents

Osteo-induktive pharmazeutische formulierungen

Info

Publication number
ATE136221T1
ATE136221T1 AT91911720T AT91911720T ATE136221T1 AT E136221 T1 ATE136221 T1 AT E136221T1 AT 91911720 T AT91911720 T AT 91911720T AT 91911720 T AT91911720 T AT 91911720T AT E136221 T1 ATE136221 T1 AT E136221T1
Authority
AT
Austria
Prior art keywords
pharmaceutical formulations
inductive
osteo
cartilage
formulations
Prior art date
Application number
AT91911720T
Other languages
English (en)
Inventor
Tobin N Gerhart
Elizabeth A Wang
Mary Jo Kriz
Original Assignee
Genetics Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetics Inst filed Critical Genetics Inst
Application granted granted Critical
Publication of ATE136221T1 publication Critical patent/ATE136221T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT91911720T 1990-06-18 1991-06-18 Osteo-induktive pharmazeutische formulierungen ATE136221T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/539,756 US5364839A (en) 1990-06-18 1990-06-18 Osteoinductive pharmaceutical formulations

Publications (1)

Publication Number Publication Date
ATE136221T1 true ATE136221T1 (de) 1996-04-15

Family

ID=24152509

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91911720T ATE136221T1 (de) 1990-06-18 1991-06-18 Osteo-induktive pharmazeutische formulierungen

Country Status (10)

Country Link
US (1) US5364839A (de)
EP (1) EP0535091B1 (de)
JP (1) JP3191937B2 (de)
AT (1) ATE136221T1 (de)
CA (1) CA2085750C (de)
DE (1) DE69118535T2 (de)
DK (1) DK0535091T3 (de)
ES (1) ES2088006T3 (de)
GR (1) GR3019901T3 (de)
WO (1) WO1991019510A1 (de)

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US6117425A (en) 1990-11-27 2000-09-12 The American National Red Cross Supplemented and unsupplemented tissue sealants, method of their production and use
US7208179B1 (en) * 1990-11-27 2007-04-24 The American National Red Cross Methods for treating disease and forming a supplemented fibrin matrix
US6197325B1 (en) 1990-11-27 2001-03-06 The American National Red Cross Supplemented and unsupplemented tissue sealants, methods of their production and use
ATE238417T1 (de) 1991-11-04 2003-05-15 Inst Genetics Llc Rekombinante knochenmorphogenetische protein heterodimere, zusammensetzungen und verfahren zur verwendung
US6291206B1 (en) 1993-09-17 2001-09-18 Genetics Institute, Inc. BMP receptor proteins
ATE319823T1 (de) 1993-12-07 2006-03-15 Inst Genetics Llc Bmp-12, bmp-13 und diese enthaltende sehne- induzierende zusammensetzungen
US5661127A (en) * 1995-05-01 1997-08-26 The Regents Of The University Of California Peptide compositions with growth factor-like activity
US6638912B2 (en) 1995-05-01 2003-10-28 The Regents Of The University Of California Peptide compositions mimicking TGF-β activity
US5780436A (en) * 1995-05-01 1998-07-14 The Regents Of The University Of California Peptide compositions with growth factor-like activity
US5902785A (en) * 1995-06-06 1999-05-11 Genetics Institute, Inc. Cartilage induction by bone morphogenetic proteins
US5700774A (en) * 1996-03-26 1997-12-23 Genetics Institute, Inc. Compositions comprising bone morphogenic proteins and truncated parathyroid hormone related peptide, and methods of inducing cartilage by administration of same
US6126682A (en) 1996-08-13 2000-10-03 Oratec Interventions, Inc. Method for treating annular fissures in intervertebral discs
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US6593290B1 (en) * 1996-11-01 2003-07-15 Genentech, Inc. Treatment of inner ear hair cells
US7255712B1 (en) 1997-04-15 2007-08-14 Active Implants Corporation Bone growth promoting implant
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IL136230A0 (en) 1997-11-28 2001-05-20 Roche Diagnostics Gmbh An active hedgehog-protein-mutant, a process for its preparation and its use for pharmaceutical purposes
US6897297B1 (en) * 1997-12-03 2005-05-24 Curis, Inc. Hydrophobically-modified protein compositions and methods
DK0953576T3 (da) * 1998-04-30 2006-03-20 Curis Inc Aktivt hedgehog-proteinkonjugat, fremgangsmåde til fremstilling heraf og anvendelse
DE19841698A1 (de) * 1998-09-11 2000-03-16 Curative Technologies Gmbh Wachstumsfaktor-enthaltende Zusammensetzung zur Heilung von Gewebeschäden
IL143866A0 (en) 1999-01-06 2002-04-21 Genentech Inc Insulin-like growth factor (igf) i mutant variants
US6727224B1 (en) 1999-02-01 2004-04-27 Genetics Institute, Llc. Methods and compositions for healing and repair of articular cartilage
DE19906096A1 (de) 1999-02-13 2000-08-17 Walter Sebald Protein mit einem Heparin-bindenden Epitop
DK1223990T3 (da) 1999-10-15 2004-11-29 Inst Genetics Llc Formuleringer af hyaluronsyre til tilförsel af osteogene proteiner
EP1265630B1 (de) 2000-03-24 2006-06-07 Genentech, Inc. Verwendung von insulin zur behandlung von knorpelkrankheiten
DE10020125A1 (de) * 2000-04-18 2001-10-25 Friedrich Schiller Uni Jena Bu Agens für den postoperativen Einsatz nach Entfernung von Knochentumoren
WO2001087323A2 (en) 2000-05-16 2001-11-22 Genentech, Inc. Method for treating cartilage disorders
DE60141236D1 (de) 2000-10-16 2010-03-18 Genentech Inc Behandlungsverfahren unter Verwendung von WISP-Polypeptiden
US20020114795A1 (en) 2000-12-22 2002-08-22 Thorne Kevin J. Composition and process for bone growth and repair
EP1399023B1 (de) 2001-06-01 2008-04-30 Wyeth Zusammensetzungen für die systemische verabreichung von sequenzen, die für knochenmorphogenese-proteinen kodieren
TWI267378B (en) 2001-06-08 2006-12-01 Wyeth Corp Calcium phosphate delivery vehicles for osteoinductive proteins
US20030124118A1 (en) * 2001-11-27 2003-07-03 Rasmus Rojkjaer Pharmaceutical composition comprising factor VII polypeptides and protein S inhibitors
EP1446152A1 (de) * 2001-11-09 2004-08-18 Novo Nordisk A/S Pharmazeutische zusammensetzung mit faktor-vii- polypeptiden und protein-s-inhibitoren
US20080057059A1 (en) * 2001-11-09 2008-03-06 Novo Nordisk Healthcare A/G Pharmaceutical Composition Comprising Factor VII Polypeptides and Protein S Inhibitors
ATE457707T1 (de) 2001-12-04 2010-03-15 Active Implants Corp Kissenlagerungsimplantate für lasttragende anwendungen
US7758653B2 (en) 2002-05-23 2010-07-20 Active Implants Corporation Implants
CN101897974B (zh) 2003-09-12 2013-09-25 惠氏公司 用于递送成骨蛋白的注射型磷酸钙固体小棒剂和糊剂
WO2006105161A2 (en) * 2005-03-30 2006-10-05 Cartilix, Inc. Coated medical device
CN101309698A (zh) * 2005-03-30 2008-11-19 惠氏公司 通过施用bmp来刺激毛发生长的方法
US7718616B2 (en) 2006-12-21 2010-05-18 Zimmer Orthobiologics, Inc. Bone growth particles and osteoinductive composition thereof
US8796206B2 (en) * 2007-11-15 2014-08-05 Amgen Inc. Aqueous formulation of erythropoiesis stimulating protein stabilised by antioxidants for parenteral administration
KR20150002874A (ko) 2008-05-05 2015-01-07 노비뮨 에스 에이 항-ｉｌ-１７ａ／ｉｌ-１７ｆ 교차-반응성 항체 및 그의 사용 방법
SG175276A1 (en) 2009-05-05 2011-11-28 Novimmune Sa Anti-il-17f antibodies and methods of use thereof
AU2011329054B2 (en) 2010-11-15 2015-05-28 Zimmer Orthobiologics, Inc. Bone void fillers
US11596712B2 (en) 2017-10-19 2023-03-07 Genera Istrazivanja D.O.O. Autologous bone graft substitute composition
KR102751476B1 (ko) * 2017-10-19 2025-01-08 제네라 이스트라지반야 디.오.오. 자가 골 이식편 대체재
WO2025168104A1 (en) * 2024-02-08 2025-08-14 Angitia Biomedicines Limited Pharmaceutical composition for inducing new bone formation and method for enhancing spinal fusion and treating bone defects

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US4563489A (en) * 1984-02-10 1986-01-07 University Of California Biodegradable organic polymer delivery system for bone morphogenetic protein
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Also Published As

Publication number Publication date
GR3019901T3 (en) 1996-08-31
US5364839A (en) 1994-11-15
WO1991019510A1 (en) 1991-12-26
EP0535091A1 (de) 1993-04-07
JPH05507930A (ja) 1993-11-11
DE69118535D1 (de) 1996-05-09
DE69118535T2 (de) 1996-09-26
ES2088006T3 (es) 1996-08-01
JP3191937B2 (ja) 2001-07-23
EP0535091B1 (de) 1996-04-03
DK0535091T3 (da) 1996-05-06
CA2085750A1 (en) 1991-12-19
CA2085750C (en) 2003-02-18

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EEFA Change of the company name
REN Ceased due to non-payment of the annual fee