ATE136221T1 - Osteo-induktive pharmazeutische formulierungen - Google Patents
Osteo-induktive pharmazeutische formulierungenInfo
- Publication number
- ATE136221T1 ATE136221T1 AT91911720T AT91911720T ATE136221T1 AT E136221 T1 ATE136221 T1 AT E136221T1 AT 91911720 T AT91911720 T AT 91911720T AT 91911720 T AT91911720 T AT 91911720T AT E136221 T1 ATE136221 T1 AT E136221T1
- Authority
- AT
- Austria
- Prior art keywords
- pharmaceutical formulations
- inductive
- osteo
- cartilage
- formulations
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/539,756 US5364839A (en) | 1990-06-18 | 1990-06-18 | Osteoinductive pharmaceutical formulations |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE136221T1 true ATE136221T1 (de) | 1996-04-15 |
Family
ID=24152509
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT91911720T ATE136221T1 (de) | 1990-06-18 | 1991-06-18 | Osteo-induktive pharmazeutische formulierungen |
Country Status (10)
Country | Link |
---|---|
US (1) | US5364839A (de) |
EP (1) | EP0535091B1 (de) |
JP (1) | JP3191937B2 (de) |
AT (1) | ATE136221T1 (de) |
CA (1) | CA2085750C (de) |
DE (1) | DE69118535T2 (de) |
DK (1) | DK0535091T3 (de) |
ES (1) | ES2088006T3 (de) |
GR (1) | GR3019901T3 (de) |
WO (1) | WO1991019510A1 (de) |
Families Citing this family (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6150328A (en) | 1986-07-01 | 2000-11-21 | Genetics Institute, Inc. | BMP products |
US5266683A (en) * | 1988-04-08 | 1993-11-30 | Stryker Corporation | Osteogenic proteins |
US6919308B2 (en) | 1988-04-08 | 2005-07-19 | Stryker Corporation | Osteogenic devices |
US6586388B2 (en) | 1988-04-08 | 2003-07-01 | Stryker Corporation | Method of using recombinant osteogenic protein to repair bone or cartilage defects |
US5422340A (en) * | 1989-09-01 | 1995-06-06 | Ammann; Arthur J. | TGF-βformulation for inducing bone growth |
GB2245559A (en) * | 1990-06-25 | 1992-01-08 | Farmos Oy | Bioceramic system for delivery of a bioactive compound. |
US7196054B1 (en) * | 1990-11-27 | 2007-03-27 | The American National Red Cross | Methods for treating wound tissue and forming a supplemented fibrin matrix |
US6197325B1 (en) | 1990-11-27 | 2001-03-06 | The American National Red Cross | Supplemented and unsupplemented tissue sealants, methods of their production and use |
US6117425A (en) | 1990-11-27 | 2000-09-12 | The American National Red Cross | Supplemented and unsupplemented tissue sealants, method of their production and use |
US6054122A (en) | 1990-11-27 | 2000-04-25 | The American National Red Cross | Supplemented and unsupplemented tissue sealants, methods of their production and use |
DE69233022T2 (de) | 1991-11-04 | 2004-02-12 | Genetics Institute, LLC, Cambridge | Rekombinante knochenmorphogenetische protein heterodimere, zusammensetzungen und verfahren zur verwendung |
US5780436A (en) * | 1995-05-01 | 1998-07-14 | The Regents Of The University Of California | Peptide compositions with growth factor-like activity |
US5661127A (en) * | 1995-05-01 | 1997-08-26 | The Regents Of The University Of California | Peptide compositions with growth factor-like activity |
US6638912B2 (en) | 1995-05-01 | 2003-10-28 | The Regents Of The University Of California | Peptide compositions mimicking TGF-β activity |
US5902785A (en) * | 1995-06-06 | 1999-05-11 | Genetics Institute, Inc. | Cartilage induction by bone morphogenetic proteins |
WO1998017190A2 (en) | 1996-10-23 | 1998-04-30 | Oratec Interventions, Inc. | Method and apparatus for treating intervertebral discs |
US5700774A (en) * | 1996-03-26 | 1997-12-23 | Genetics Institute, Inc. | Compositions comprising bone morphogenic proteins and truncated parathyroid hormone related peptide, and methods of inducing cartilage by administration of same |
US6126682A (en) | 1996-08-13 | 2000-10-03 | Oratec Interventions, Inc. | Method for treating annular fissures in intervertebral discs |
EP1459691A1 (de) | 1996-10-23 | 2004-09-22 | Oratec Interventions, Inc. | Verfahren und vorrichtung zur behandlung von zwischenwirbelscheiben |
US6593290B1 (en) * | 1996-11-01 | 2003-07-15 | Genentech, Inc. | Treatment of inner ear hair cells |
US7255712B1 (en) | 1997-04-15 | 2007-08-14 | Active Implants Corporation | Bone growth promoting implant |
CN1068793C (zh) * | 1997-04-17 | 2001-07-25 | 中国人民解放军第四军医大学全军创伤骨科研究所 | 骨生长刺激素注射剂及其制备方法 |
IL136230A0 (en) | 1997-11-28 | 2001-05-20 | Roche Diagnostics Gmbh | An active hedgehog-protein-mutant, a process for its preparation and its use for pharmaceutical purposes |
US6897297B1 (en) * | 1997-12-03 | 2005-05-24 | Curis, Inc. | Hydrophobically-modified protein compositions and methods |
EP0953576B1 (de) * | 1998-04-30 | 2005-11-02 | Curis, Inc. | Aktives Hedgehog-Protein-Konjugat, Verfahren zur Herstellung und Verwendung |
DE19841698A1 (de) * | 1998-09-11 | 2000-03-16 | Curative Technologies Gmbh | Wachstumsfaktor-enthaltende Zusammensetzung zur Heilung von Gewebeschäden |
IL143866A0 (en) | 1999-01-06 | 2002-04-21 | Genentech Inc | Insulin-like growth factor (igf) i mutant variants |
DE19906096A1 (de) | 1999-02-13 | 2000-08-17 | Walter Sebald | Protein mit einem Heparin-bindenden Epitop |
PT1223990E (pt) | 1999-10-15 | 2004-12-31 | Fidia Advanced Biopolymers Srl | Formulacoes de acido hialuronico para administracao de proteinas osteogenicas |
DE60120372T2 (de) | 2000-03-24 | 2007-07-05 | Genentech Inc., San Francisco | Verwendung von insulin zur behandlung von knorpelkrankheiten |
DE10020125A1 (de) * | 2000-04-18 | 2001-10-25 | Friedrich Schiller Uni Jena Bu | Agens für den postoperativen Einsatz nach Entfernung von Knochentumoren |
AU2001263215A1 (en) | 2000-05-16 | 2001-11-26 | Genentech Inc. | Method for treating cartilage disorders |
WO2002033085A2 (en) | 2000-10-16 | 2002-04-25 | Genentech, Inc. | Wisp polypeptides and therapeutical applications thereof |
US20020114795A1 (en) | 2000-12-22 | 2002-08-22 | Thorne Kevin J. | Composition and process for bone growth and repair |
TWI267378B (en) | 2001-06-08 | 2006-12-01 | Wyeth Corp | Calcium phosphate delivery vehicles for osteoinductive proteins |
WO2003039587A1 (en) * | 2001-11-09 | 2003-05-15 | Novo Nordisk Health Care Ag | Pharmaceutical composition comprising factor vii polypeptides and protein s inhibitors |
US20030124118A1 (en) * | 2001-11-27 | 2003-07-03 | Rasmus Rojkjaer | Pharmaceutical composition comprising factor VII polypeptides and protein S inhibitors |
US20080057059A1 (en) * | 2001-11-09 | 2008-03-06 | Novo Nordisk Healthcare A/G | Pharmaceutical Composition Comprising Factor VII Polypeptides and Protein S Inhibitors |
AU2002353484A1 (en) | 2001-12-04 | 2003-06-17 | Discure Ltd. | Cushion bearing implants for load bearing applications |
CN100586398C (zh) | 2002-05-23 | 2010-02-03 | 活性移植公司 | 植入体 |
KR20060133961A (ko) | 2003-09-12 | 2006-12-27 | 와이어쓰 | 골형성 단백질 전달용의 주사 가능한 인산칼슘 고형 로드및 페이스트 |
WO2006105161A2 (en) * | 2005-03-30 | 2006-10-05 | Cartilix, Inc. | Coated medical device |
BRPI0609504A2 (pt) * | 2005-03-30 | 2010-04-13 | Wyeth Corp | métodos para estimular o crescimento capilar administrando proteìnas morfogenéticas ósseas (bmps) |
US7718616B2 (en) | 2006-12-21 | 2010-05-18 | Zimmer Orthobiologics, Inc. | Bone growth particles and osteoinductive composition thereof |
ES2962777T3 (es) * | 2007-11-15 | 2024-03-21 | Amgen Inc | Formulación acuosa de anticuerpos estabilizada por antioxidantes para la administración parenteral |
CN104628855A (zh) | 2008-05-05 | 2015-05-20 | 诺维莫尼公司 | 抗il-17a/il-17f交叉反应性抗体及其使用方法 |
AU2010244142B2 (en) | 2009-05-05 | 2016-07-21 | Novimmune Sa | Anti-IL-17F antibodies and methods of use thereof |
JP2013542837A (ja) | 2010-11-15 | 2013-11-28 | ジンマー オーソバイオロジクス,インコーポレイティド | 骨空隙充填剤 |
US11596712B2 (en) | 2017-10-19 | 2023-03-07 | Genera Istrazivanja D.O.O. | Autologous bone graft substitute composition |
JP2020537590A (ja) * | 2017-10-19 | 2020-12-24 | パーフォーム バイオロジクス インコーポレイテッドPerform Biologics, Inc. | 自家骨移植代替物 |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4186448A (en) * | 1976-04-16 | 1980-02-05 | Brekke John H | Device and method for treating and healing a newly created bone void |
SU733665A1 (ru) * | 1978-03-30 | 1980-05-15 | Семипалатинский Государственный Медицинский Институт | Способ остеосинтеза трубчатых костей |
US4430760A (en) * | 1981-12-18 | 1984-02-14 | Collagen Corporation | Nonstress-bearing implantable bone prosthesis |
US4440750A (en) * | 1982-02-12 | 1984-04-03 | Collagen Corporation | Osteogenic composition and method |
US4795804A (en) * | 1983-08-16 | 1989-01-03 | The Regents Of The University Of California | Bone morphogenetic agents |
JPS60100516A (ja) * | 1983-11-04 | 1985-06-04 | Takeda Chem Ind Ltd | 徐放型マイクロカプセルの製造法 |
US4563489A (en) * | 1984-02-10 | 1986-01-07 | University Of California | Biodegradable organic polymer delivery system for bone morphogenetic protein |
US4596574A (en) * | 1984-05-14 | 1986-06-24 | The Regents Of The University Of California | Biodegradable porous ceramic delivery system for bone morphogenetic protein |
EP0166263A1 (de) * | 1984-05-31 | 1986-01-02 | Green Cross Corporation | Füllmaterial für Knochendefekte oder Knochenhohlräume, Kit oder Set zur Herstellung dieses Füllmaterials |
ZA874681B (en) * | 1986-07-01 | 1988-04-27 | Genetics Inst | Novel osteoinductive factors |
US5106748A (en) * | 1986-07-01 | 1992-04-21 | Genetics Institute, Inc. | Dna sequences encoding 5 proteins |
US4877864A (en) * | 1987-03-26 | 1989-10-31 | Genetics Institute, Inc. | Osteoinductive factors |
US5013649A (en) * | 1986-07-01 | 1991-05-07 | Genetics Institute, Inc. | DNA sequences encoding osteoinductive products |
IL83003A (en) * | 1986-07-01 | 1995-07-31 | Genetics Inst | Factors that soak bone formation |
US4979959A (en) * | 1986-10-17 | 1990-12-25 | Bio-Metric Systems, Inc. | Biocompatible coating for solid surfaces |
US4902296A (en) * | 1986-10-29 | 1990-02-20 | The University Of Virginia Alumni Patents Foundation | Use of demineralized bone matrix in the repair of segmental defects |
WO1989004646A1 (en) * | 1987-11-13 | 1989-06-01 | Jefferies Steven R | Bone repair material and delayed drug delivery |
IL84911A (en) * | 1987-12-22 | 1993-04-04 | Yissum Res Dev Co | Processes for the preparation of collagen products, and pharmaceutical compositions containing the same |
AU3433989A (en) * | 1988-04-06 | 1989-11-03 | Celtrix Laboratories, Inc. | Bone-inducing protein |
KR900700617A (ko) * | 1988-04-08 | 1990-08-16 | 브루스 엠. 에이센 | 뼈 및 연골 유도 조성물 |
US4968590A (en) * | 1988-04-08 | 1990-11-06 | Stryker Corporation | Osteogenic proteins and polypeptides |
US5108436A (en) * | 1988-09-29 | 1992-04-28 | Collagen Corporation | Implant fixation |
DE3939346A1 (de) * | 1989-11-29 | 1991-06-06 | Behringwerke Ag | Arzneimitel zur subkutanen oder intramuskulaeren applikation enthaltend polypeptide |
-
1990
- 1990-06-18 US US07/539,756 patent/US5364839A/en not_active Expired - Lifetime
-
1991
- 1991-06-18 CA CA002085750A patent/CA2085750C/en not_active Expired - Fee Related
- 1991-06-18 JP JP51154491A patent/JP3191937B2/ja not_active Expired - Fee Related
- 1991-06-18 WO PCT/US1991/004337 patent/WO1991019510A1/en active IP Right Grant
- 1991-06-18 DE DE69118535T patent/DE69118535T2/de not_active Expired - Fee Related
- 1991-06-18 AT AT91911720T patent/ATE136221T1/de not_active IP Right Cessation
- 1991-06-18 DK DK91911720.0T patent/DK0535091T3/da active
- 1991-06-18 EP EP91911720A patent/EP0535091B1/de not_active Expired - Lifetime
- 1991-06-18 ES ES91911720T patent/ES2088006T3/es not_active Expired - Lifetime
-
1996
- 1996-05-13 GR GR960401283T patent/GR3019901T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
DE69118535D1 (de) | 1996-05-09 |
EP0535091A1 (de) | 1993-04-07 |
GR3019901T3 (en) | 1996-08-31 |
JPH05507930A (ja) | 1993-11-11 |
CA2085750A1 (en) | 1991-12-19 |
JP3191937B2 (ja) | 2001-07-23 |
EP0535091B1 (de) | 1996-04-03 |
DE69118535T2 (de) | 1996-09-26 |
ES2088006T3 (es) | 1996-08-01 |
DK0535091T3 (da) | 1996-05-06 |
WO1991019510A1 (en) | 1991-12-26 |
US5364839A (en) | 1994-11-15 |
CA2085750C (en) | 2003-02-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
EEFA | Change of the company name | ||
REN | Ceased due to non-payment of the annual fee |