ATE136221T1 - Osteo-induktive pharmazeutische formulierungen - Google Patents

Osteo-induktive pharmazeutische formulierungen

Info

Publication number
ATE136221T1
ATE136221T1 AT91911720T AT91911720T ATE136221T1 AT E136221 T1 ATE136221 T1 AT E136221T1 AT 91911720 T AT91911720 T AT 91911720T AT 91911720 T AT91911720 T AT 91911720T AT E136221 T1 ATE136221 T1 AT E136221T1
Authority
AT
Austria
Prior art keywords
pharmaceutical formulations
inductive
osteo
cartilage
formulations
Prior art date
Application number
AT91911720T
Other languages
English (en)
Inventor
Tobin N Gerhart
Elizabeth A Wang
Mary Jo Kriz
Original Assignee
Genetics Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetics Inst filed Critical Genetics Inst
Application granted granted Critical
Publication of ATE136221T1 publication Critical patent/ATE136221T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT91911720T 1990-06-18 1991-06-18 Osteo-induktive pharmazeutische formulierungen ATE136221T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/539,756 US5364839A (en) 1990-06-18 1990-06-18 Osteoinductive pharmaceutical formulations

Publications (1)

Publication Number Publication Date
ATE136221T1 true ATE136221T1 (de) 1996-04-15

Family

ID=24152509

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91911720T ATE136221T1 (de) 1990-06-18 1991-06-18 Osteo-induktive pharmazeutische formulierungen

Country Status (10)

Country Link
US (1) US5364839A (de)
EP (1) EP0535091B1 (de)
JP (1) JP3191937B2 (de)
AT (1) ATE136221T1 (de)
CA (1) CA2085750C (de)
DE (1) DE69118535T2 (de)
DK (1) DK0535091T3 (de)
ES (1) ES2088006T3 (de)
GR (1) GR3019901T3 (de)
WO (1) WO1991019510A1 (de)

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US7189410B1 (en) * 1990-11-27 2007-03-13 The American National Red Cross Supplemented and unsupplemented tissue sealants, methods of their production and use
US6054122A (en) 1990-11-27 2000-04-25 The American National Red Cross Supplemented and unsupplemented tissue sealants, methods of their production and use
US6197325B1 (en) 1990-11-27 2001-03-06 The American National Red Cross Supplemented and unsupplemented tissue sealants, methods of their production and use
WO1993009229A1 (en) 1991-11-04 1993-05-13 Genetics Institute, Inc. Recombinant bone morphogenetic protein heterodimers, compositions and methods of use
US5661127A (en) * 1995-05-01 1997-08-26 The Regents Of The University Of California Peptide compositions with growth factor-like activity
US5780436A (en) * 1995-05-01 1998-07-14 The Regents Of The University Of California Peptide compositions with growth factor-like activity
US6638912B2 (en) 1995-05-01 2003-10-28 The Regents Of The University Of California Peptide compositions mimicking TGF-β activity
US5902785A (en) * 1995-06-06 1999-05-11 Genetics Institute, Inc. Cartilage induction by bone morphogenetic proteins
US5700774A (en) * 1996-03-26 1997-12-23 Genetics Institute, Inc. Compositions comprising bone morphogenic proteins and truncated parathyroid hormone related peptide, and methods of inducing cartilage by administration of same
US6126682A (en) 1996-08-13 2000-10-03 Oratec Interventions, Inc. Method for treating annular fissures in intervertebral discs
AU4996097A (en) 1996-10-23 1998-05-15 Oratec Interventions, Inc. Method and apparatus for treating intervertebral discs
EP1006885B1 (de) 1996-10-23 2006-09-20 Oratec Interventions, Inc. Vorrichtung zur behandlung von zwischenwirbelscheiben
US6593290B1 (en) * 1996-11-01 2003-07-15 Genentech, Inc. Treatment of inner ear hair cells
US6403764B1 (en) 1999-01-06 2002-06-11 Genentech, Inc. Insulin-like growth factor-1 protein variants
US7255712B1 (en) 1997-04-15 2007-08-14 Active Implants Corporation Bone growth promoting implant
CN1068793C (zh) * 1997-04-17 2001-07-25 中国人民解放军第四军医大学全军创伤骨科研究所 骨生长刺激素注射剂及其制备方法
CA2312009A1 (en) * 1997-11-28 1999-06-10 Roche Diagnostics Gmbh An active hedgehog-protein-mutant, a process for its preparation and its use for pharmaceutical purposes
US6897297B1 (en) * 1997-12-03 2005-05-24 Curis, Inc. Hydrophobically-modified protein compositions and methods
ATE308563T1 (de) * 1998-04-30 2005-11-15 Curis Inc Aktives hedgehog-protein-konjugat, verfahren zur herstellung und verwendung
DE19841698A1 (de) * 1998-09-11 2000-03-16 Curative Technologies Gmbh Wachstumsfaktor-enthaltende Zusammensetzung zur Heilung von Gewebeschäden
DE19906096A1 (de) 1999-02-13 2000-08-17 Walter Sebald Protein mit einem Heparin-bindenden Epitop
PT1223990E (pt) 1999-10-15 2004-12-31 Fidia Advanced Biopolymers Srl Formulacoes de acido hialuronico para administracao de proteinas osteogenicas
WO2001072323A2 (en) 2000-03-24 2001-10-04 Genentech, Inc. Use of insulin for the treatment of cartilagenous disorders
DE10020125A1 (de) * 2000-04-18 2001-10-25 Friedrich Schiller Uni Jena Bu Agens für den postoperativen Einsatz nach Entfernung von Knochentumoren
WO2001087323A2 (en) 2000-05-16 2001-11-22 Genentech, Inc. Method for treating cartilage disorders
AU2437702A (en) 2000-10-16 2002-04-29 Genentech Inc Methods of treatment using wisp polypeptides
US20020114795A1 (en) 2000-12-22 2002-08-22 Thorne Kevin J. Composition and process for bone growth and repair
TWI267378B (en) 2001-06-08 2006-12-01 Wyeth Corp Calcium phosphate delivery vehicles for osteoinductive proteins
US20080057059A1 (en) * 2001-11-09 2008-03-06 Novo Nordisk Healthcare A/G Pharmaceutical Composition Comprising Factor VII Polypeptides and Protein S Inhibitors
US20030124118A1 (en) * 2001-11-27 2003-07-03 Rasmus Rojkjaer Pharmaceutical composition comprising factor VII polypeptides and protein S inhibitors
JP2005510516A (ja) * 2001-11-09 2005-04-21 ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト Ｖｉｉ因子ポリペプチドおよびプロテインｓ阻害剤を含む薬学的組成物
ATE457707T1 (de) 2001-12-04 2010-03-15 Active Implants Corp Kissenlagerungsimplantate für lasttragende anwendungen
WO2003099156A2 (en) 2002-05-23 2003-12-04 Discure, Ltd. Joint and dental implants
EP2374471A1 (de) 2003-09-12 2011-10-12 Wyeth LLC Injizierbare härtbare Calciumphosphat-Pasten zur Abgabe osteogener Proteine
AU2006230434A1 (en) * 2005-03-30 2006-10-05 Wyeth Methods for stimulating hair growth by administering BMPs
WO2006105161A2 (en) * 2005-03-30 2006-10-05 Cartilix, Inc. Coated medical device
US7718616B2 (en) 2006-12-21 2010-05-18 Zimmer Orthobiologics, Inc. Bone growth particles and osteoinductive composition thereof
ES2962777T3 (es) 2007-11-15 2024-03-21 Amgen Inc Formulación acuosa de anticuerpos estabilizada por antioxidantes para la administración parenteral
CA2721713C (en) 2008-05-05 2019-07-09 Novimmune Sa Anti-il-17a/il-17f cross-reactive antibodies and methods of use thereof
MX2011011729A (es) 2009-05-05 2012-04-10 Novimmune Sa Anticuerpo anti il-17f y metodos de uso de los mismos.
AU2011329054B2 (en) 2010-11-15 2015-05-28 Zimmer Orthobiologics, Inc. Bone void fillers
JP2020537590A (ja) * 2017-10-19 2020-12-24 パーフォーム バイオロジクス インコーポレイテッドＰｅｒｆｏｒｍ Ｂｉｏｌｏｇｉｃｓ， Ｉｎｃ． 自家骨移植代替物
US11596712B2 (en) 2017-10-19 2023-03-07 Genera Istrazivanja D.O.O. Autologous bone graft substitute composition

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US4430760A (en) * 1981-12-18 1984-02-14 Collagen Corporation Nonstress-bearing implantable bone prosthesis
US4440750A (en) * 1982-02-12 1984-04-03 Collagen Corporation Osteogenic composition and method
US4795804A (en) * 1983-08-16 1989-01-03 The Regents Of The University Of California Bone morphogenetic agents
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US4563489A (en) * 1984-02-10 1986-01-07 University Of California Biodegradable organic polymer delivery system for bone morphogenetic protein
US4596574A (en) * 1984-05-14 1986-06-24 The Regents Of The University Of California Biodegradable porous ceramic delivery system for bone morphogenetic protein
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US4902296A (en) * 1986-10-29 1990-02-20 The University Of Virginia Alumni Patents Foundation Use of demineralized bone matrix in the repair of segmental defects
CA1339083C (en) * 1987-11-13 1997-07-29 Steven R. Jefferies Bone repair material and delayed drug delivery system
IL84911A (en) * 1987-12-22 1993-04-04 Yissum Res Dev Co Processes for the preparation of collagen products, and pharmaceutical compositions containing the same
JPH04505607A (ja) * 1988-04-06 1992-10-01 セルトリックス　ファーマシューティカルズ　インコーポレイテッド 骨誘導タンパク
US4968590A (en) * 1988-04-08 1990-11-06 Stryker Corporation Osteogenic proteins and polypeptides
AU645244B2 (en) * 1988-04-08 1994-01-13 Genetics Institute, Llc Bone and cartilage inductive compositions
US5108436A (en) * 1988-09-29 1992-04-28 Collagen Corporation Implant fixation
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Also Published As

Publication number Publication date
US5364839A (en) 1994-11-15
WO1991019510A1 (en) 1991-12-26
ES2088006T3 (es) 1996-08-01
EP0535091B1 (de) 1996-04-03
JPH05507930A (ja) 1993-11-11
DK0535091T3 (da) 1996-05-06
JP3191937B2 (ja) 2001-07-23
DE69118535T2 (de) 1996-09-26
GR3019901T3 (en) 1996-08-31
CA2085750A1 (en) 1991-12-19
DE69118535D1 (de) 1996-05-09
EP0535091A1 (de) 1993-04-07
CA2085750C (en) 2003-02-18

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EEFA Change of the company name
REN Ceased due to non-payment of the annual fee