ATE109568T1 - Verfahren zur differenzierung von leukozyten mit hilfe eines durchflusszellmessgerätes. - Google Patents
Verfahren zur differenzierung von leukozyten mit hilfe eines durchflusszellmessgerätes.Info
- Publication number
- ATE109568T1 ATE109568T1 AT90305229T AT90305229T ATE109568T1 AT E109568 T1 ATE109568 T1 AT E109568T1 AT 90305229 T AT90305229 T AT 90305229T AT 90305229 T AT90305229 T AT 90305229T AT E109568 T1 ATE109568 T1 AT E109568T1
- Authority
- AT
- Austria
- Prior art keywords
- differentiation
- procedure
- flow cell
- lytic agent
- cell meter
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 230000004069 differentiation Effects 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 abstract 3
- 230000002101 lytic effect Effects 0.000 abstract 3
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 238000000684 flow cytometry Methods 0.000 abstract 2
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 239000003599 detergent Substances 0.000 abstract 1
- 210000000265 leukocyte Anatomy 0.000 abstract 1
- 229960005323 phenoxyethanol Drugs 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5094—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/101666—Particle count or volume standard or control [e.g., platelet count standards, etc.]
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Ecology (AREA)
- Food Science & Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Detergent Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35210689A | 1989-05-15 | 1989-05-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE109568T1 true ATE109568T1 (de) | 1994-08-15 |
Family
ID=23383823
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90305229T ATE109568T1 (de) | 1989-05-15 | 1990-05-15 | Verfahren zur differenzierung von leukozyten mit hilfe eines durchflusszellmessgerätes. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5510267A (de) |
| EP (1) | EP0398652B1 (de) |
| JP (1) | JPH0726956B2 (de) |
| AT (1) | ATE109568T1 (de) |
| AU (1) | AU636607B2 (de) |
| CA (1) | CA2016699C (de) |
| DE (1) | DE69011198T2 (de) |
| ES (1) | ES2060949T3 (de) |
Families Citing this family (92)
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| JP2565844B2 (ja) * | 1992-02-07 | 1996-12-18 | アボツト・ラボラトリーズ | 細胞溶解処理条件下で異種細胞集団を正確に計数し,感受性に関する格付けを行う方法 |
| US6509192B1 (en) * | 1992-02-24 | 2003-01-21 | Coulter International Corp. | Quality control method |
| EP0582736A1 (de) * | 1992-08-11 | 1994-02-16 | Abbott Laboratories | Hüllflüssigkeitszusammensetzung für Durchflusszytometrie zur Eliminierung von Erythrocyten und Konservierung von nukleierten Zellen |
| DE69327775T2 (de) * | 1992-11-19 | 2000-06-21 | Sysmex Corp., Kobe | Verfahren zur Vorbehandlung für Blutanalyse |
| US6812032B1 (en) | 1993-01-21 | 2004-11-02 | Cdc Technologies, Inc. | Apparatus and method for making a plurality of reagent mixtures and analyzing particle distributions of the reagent mixtures |
| JP3355038B2 (ja) * | 1994-08-03 | 2002-12-09 | シスメックス株式会社 | 白血球分類方法 |
| FR2733835B1 (fr) * | 1995-05-03 | 1997-07-18 | Hycel Groupe Lisabio | Procede et dispositif de detection du point de lyse de globules rouges |
| US5639630A (en) * | 1995-05-16 | 1997-06-17 | Bayer Corporation | Method and reagent composition for performing leukocyte differential counts on fresh and aged whole blood samples, based on intrinsic peroxidase activity of leukocytes |
| US5817518A (en) * | 1995-12-18 | 1998-10-06 | Coulter International Corp. | Reagent and method for differential determination of leukocytes in blood |
| WO1997022870A1 (en) * | 1995-12-18 | 1997-06-26 | Center For Laboratory Technology, Inc. | Multi-parameter hematology apparatus and method |
| US5817519A (en) * | 1995-12-28 | 1998-10-06 | Bayer Corporation | Automated method and device for identifying and quantifying platelets and for determining platelet activation state using whole blood samples |
| US6025201A (en) * | 1995-12-28 | 2000-02-15 | Bayer Corporation | Highly sensitive, accurate, and precise automated method and device for identifying and quantifying platelets and for determining platelet activation state using whole blood samples |
| US5874310A (en) * | 1997-11-21 | 1999-02-23 | Coulter International Corp. | Method for differentiation of nucleated red blood cells |
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| US6304328B1 (en) * | 1998-08-14 | 2001-10-16 | Research Foundation Of State University Of New York, The Office Of Technology Licensing, Suny | Non-contact temperature and concentration measurement on liquid surfaces |
| US6067157A (en) * | 1998-10-09 | 2000-05-23 | University Of Washington | Dual large angle light scattering detection |
| US6423505B1 (en) | 1998-12-03 | 2002-07-23 | Becton Dickinson And Company | Methods and reagents for quantitation of HLA-DR and CD11b expression on peripheral blood cells |
| US6200766B1 (en) | 1998-12-03 | 2001-03-13 | Becton Dickinson And Company | Methods and reagents for quantitation of HLA-DR expression on peripheral blood cells |
| US6210969B1 (en) * | 1999-04-28 | 2001-04-03 | Coulter International Corp. | Composition and method for differentiation of basophil and eosinophil subpopulations of leukocytes in blood |
| US6214625B1 (en) * | 1999-04-28 | 2001-04-10 | Coulter International Corp. | Composition and method for differentiation of basophils and eosinophils in blood |
| US6232125B1 (en) | 1999-08-09 | 2001-05-15 | Coulter International Corp. | Method and apparatus for differentiating and enumerating leukocytes |
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| US7242474B2 (en) * | 2004-07-27 | 2007-07-10 | Cox James A | Cytometer having fluid core stream position control |
| US7641856B2 (en) * | 2004-05-14 | 2010-01-05 | Honeywell International Inc. | Portable sample analyzer with removable cartridge |
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| US7061595B2 (en) * | 2000-08-02 | 2006-06-13 | Honeywell International Inc. | Miniaturized flow controller with closed loop regulation |
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| JP4097597B2 (ja) | 2001-06-01 | 2008-06-11 | 富士通株式会社 | 光磁気記録媒体装置 |
| US6869798B2 (en) * | 2003-04-17 | 2005-03-22 | Clinical Diagnostics Solutions, Inc. | Lytic reagent composition for leukocyte differential analysis |
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| US20060118359A1 (en) * | 2004-11-02 | 2006-06-08 | Purvis Harrison G | Temporary railing for a building including tensioning apparatus and associated methods |
| FR2883972B1 (fr) * | 2005-03-31 | 2007-11-16 | C2 Diagnostics Sa | Procede pour l'analyse d'un echantillon de sang et appareil et reactif pour sa mise en oeuvre |
| JP4965561B2 (ja) | 2005-04-29 | 2012-07-04 | ハネウェル・インターナショナル・インコーポレーテッド | サイトメータ細胞計数及びサイズ測定システム |
| US8273294B2 (en) * | 2005-07-01 | 2012-09-25 | Honeywell International Inc. | Molded cartridge with 3-D hydrodynamic focusing |
| CN101252994B (zh) * | 2005-07-01 | 2011-04-13 | 霍尼韦尔国际公司 | 用于红血细胞分析的微流体卡 |
| WO2007005974A2 (en) * | 2005-07-01 | 2007-01-11 | Honeywell International, Inc. | A flow metered analyzer |
| US7843563B2 (en) * | 2005-08-16 | 2010-11-30 | Honeywell International Inc. | Light scattering and imaging optical system |
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| JP5175213B2 (ja) * | 2005-12-22 | 2013-04-03 | ハネウェル・インターナショナル・インコーポレーテッド | 携帯用サンプル分析システム |
| CN101389947B (zh) * | 2005-12-29 | 2013-08-21 | 霍尼韦尔国际公司 | 微流格式的测定工具 |
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| US7816135B2 (en) | 2007-07-05 | 2010-10-19 | Becton, Dickinson And Company | Method of analyzing lymphocytes |
| CN101349644B (zh) * | 2007-07-20 | 2012-06-27 | 深圳迈瑞生物医疗电子股份有限公司 | 一种白细胞分类试剂和其使用方法 |
| US8102161B2 (en) * | 2007-09-25 | 2012-01-24 | Tdk Corporation | Stable output in a switching power supply by smoothing the output of the secondary coil |
| JP2009083382A (ja) * | 2007-10-01 | 2009-04-23 | Brother Ind Ltd | 画像形成装置および画像処理プログラム |
| CN101470108B (zh) | 2007-12-24 | 2013-11-27 | 深圳迈瑞生物医疗电子股份有限公司 | 一种对白细胞进行分类的试剂和方法 |
| CN101475754A (zh) * | 2008-01-04 | 2009-07-08 | 深圳迈瑞生物医疗电子股份有限公司 | 不对称菁类荧光染料,组合物及在生物样品染色中的用途 |
| EP2247746A4 (de) * | 2008-01-31 | 2012-08-01 | Amyris Inc | Verfahren zur überwachung von stoffwechselwegen |
| JP2009236798A (ja) * | 2008-03-28 | 2009-10-15 | Sysmex Corp | 好塩基球の分類計数方法 |
| CN102016577B (zh) * | 2008-05-09 | 2015-06-17 | 希森美康株式会社 | 血液分析装置,血液分析方法及溶血剂 |
| CN101602762B (zh) * | 2008-06-10 | 2013-10-16 | 深圳迈瑞生物医疗电子股份有限公司 | 不对称菁类化合物、其制备方法及应用 |
| US20100034704A1 (en) * | 2008-08-06 | 2010-02-11 | Honeywell International Inc. | Microfluidic cartridge channel with reduced bubble formation |
| US8037354B2 (en) | 2008-09-18 | 2011-10-11 | Honeywell International Inc. | Apparatus and method for operating a computing platform without a battery pack |
| CN101726579B (zh) * | 2008-10-17 | 2014-06-18 | 深圳迈瑞生物医疗电子股份有限公司 | 血液检测试剂和方法 |
| US8367358B2 (en) * | 2008-12-17 | 2013-02-05 | Shenzhen Mindray Bio-Medical Electronics Co., Ltd. | Reagent, kit and method for differentiating and counting leukocytes |
| CN101988082B (zh) * | 2009-07-31 | 2015-04-08 | 深圳迈瑞生物医疗电子股份有限公司 | 白细胞分类计数试剂、试剂盒及其制备方法和白细胞分类计数的方法 |
| JP4907705B2 (ja) * | 2009-09-29 | 2012-04-04 | シスメックス株式会社 | 尿中赤血球分析用試薬 |
| US9091677B2 (en) | 2010-08-09 | 2015-07-28 | Beckman Coulter, Inc. | Isotonic buffered composition and method that enables counting of cells |
| US8741234B2 (en) | 2011-12-27 | 2014-06-03 | Honeywell International Inc. | Disposable cartridge for fluid analysis |
| US8741235B2 (en) | 2011-12-27 | 2014-06-03 | Honeywell International Inc. | Two step sample loading of a fluid analysis cartridge |
| US8663583B2 (en) | 2011-12-27 | 2014-03-04 | Honeywell International Inc. | Disposable cartridge for fluid analysis |
| US8741233B2 (en) | 2011-12-27 | 2014-06-03 | Honeywell International Inc. | Disposable cartridge for fluid analysis |
| EP2972321B1 (de) * | 2013-03-12 | 2021-02-17 | Abbott Laboratories | System zur untersuchung weisser blutkörperchen |
| WO2015073952A1 (en) * | 2013-11-15 | 2015-05-21 | University Of Maryland | Integrated and standalone label and reagent-free microfluidic devices and microsystems for differential white blood cell counts |
| JP6976167B2 (ja) | 2014-06-13 | 2021-12-08 | キュー−リネア エービー | 微生物の検出及び特徴付け方法 |
| GB201507026D0 (en) | 2015-04-24 | 2015-06-10 | Linea Ab Q | Medical sample transportation container |
| NO340218B1 (en) | 2015-07-10 | 2017-03-20 | Marine Harvest Norway As | Device and method for removing parasites on fish |
| EP3371591A4 (de) | 2015-11-02 | 2018-11-14 | Chiranjit Deka | Lichtstreuerbasierte vorrichtung und verfahren zur hämatologieanalyse mit verwendung von nur drei detektoren |
| GB2554767A (en) | 2016-04-21 | 2018-04-11 | Q Linea Ab | Detecting and characterising a microorganism |
| JP7414529B2 (ja) | 2017-06-07 | 2024-01-16 | シファメド・ホールディングス・エルエルシー | 血管内流体移動デバイス、システム、および使用方法 |
| CN111556763B (zh) | 2017-11-13 | 2023-09-01 | 施菲姆德控股有限责任公司 | 血管内流体运动装置、系统 |
| EP3746149B1 (de) | 2018-02-01 | 2025-08-06 | Shifamed Holdings, LLC | Intravaskuläre blutpumpen |
| EP3776051B1 (de) | 2018-03-30 | 2024-03-06 | Idexx Laboratories, Inc. | Laseroptikanordnung eines durchflusszytometers |
| WO2020028537A1 (en) | 2018-07-31 | 2020-02-06 | Shifamed Holdings, Llc | Intravascaular blood pumps and methods of use |
| WO2020073047A1 (en) | 2018-10-05 | 2020-04-09 | Shifamed Holdings, Llc | Intravascular blood pumps and methods of use |
| WO2021011473A1 (en) | 2019-07-12 | 2021-01-21 | Shifamed Holdings, Llc | Intravascular blood pumps and methods of manufacture and use |
| WO2021016372A1 (en) | 2019-07-22 | 2021-01-28 | Shifamed Holdings, Llc | Intravascular blood pumps with struts and methods of use and manufacture |
| US12465748B2 (en) | 2019-08-07 | 2025-11-11 | Supira Medical, Inc. | Catheter blood pumps and collapsible pump housings |
| US12121713B2 (en) | 2019-09-25 | 2024-10-22 | Shifamed Holdings, Llc | Catheter blood pumps and collapsible blood conduits |
| EP4501393A3 (de) | 2019-09-25 | 2025-04-09 | Shifamed Holdings, LLC | Katheterblutpumpen und zusammenklappbare pumpengehäuse |
| WO2021062265A1 (en) | 2019-09-25 | 2021-04-01 | Shifamed Holdings, Llc | Intravascular blood pump systems and methods of use and control thereof |
| EP4072650A4 (de) | 2019-12-11 | 2024-01-10 | Shifamed Holdings, LLC | Absteigende aorten- und hohlvenenblutpumpen |
| CN115917292B (zh) | 2020-06-17 | 2023-08-25 | Idexx实验室公司 | 流式细胞仪及其激光光学组件 |
| CN115718028A (zh) * | 2022-11-28 | 2023-02-28 | 山东博群生物技术有限公司 | 一种流式细胞仪分析用溶血素及其制备方法 |
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| US3874852A (en) * | 1974-07-05 | 1975-04-01 | Coulter Diagnostics Inc | Reagent and method for determining leukocytes and hemoglobin in the blood |
| US3962125A (en) * | 1975-01-13 | 1976-06-08 | Coulter Diagnostics, Inc. | Multi-purpose diluent for use in blood analysis by electronic instrumentation of the coulter type |
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| US4099917A (en) * | 1977-07-21 | 1978-07-11 | Technicon Instruments Corporation | Process for preparing a cell suspension from blood for discrimination of white blood cells and platelets from other blood particles |
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| US4284412A (en) * | 1979-07-13 | 1981-08-18 | Ortho Diagnostics, Inc. | Method and apparatus for automated identification and enumeration of specified blood cell subclasses |
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-
1990
- 1990-05-14 CA CA002016699A patent/CA2016699C/en not_active Expired - Lifetime
- 1990-05-15 AT AT90305229T patent/ATE109568T1/de not_active IP Right Cessation
- 1990-05-15 DE DE69011198T patent/DE69011198T2/de not_active Expired - Fee Related
- 1990-05-15 JP JP2125266A patent/JPH0726956B2/ja not_active Expired - Lifetime
- 1990-05-15 ES ES90305229T patent/ES2060949T3/es not_active Expired - Lifetime
- 1990-05-15 EP EP90305229A patent/EP0398652B1/de not_active Expired - Lifetime
- 1990-05-15 AU AU55037/90A patent/AU636607B2/en not_active Ceased
-
1992
- 1992-08-24 US US07/934,282 patent/US5510267A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2016699C (en) | 2003-11-18 |
| AU636607B2 (en) | 1993-05-06 |
| DE69011198T2 (de) | 1995-01-19 |
| JPH0726956B2 (ja) | 1995-03-29 |
| CA2016699A1 (en) | 1990-11-15 |
| JPH034171A (ja) | 1991-01-10 |
| DE69011198D1 (de) | 1994-09-08 |
| EP0398652B1 (de) | 1994-08-03 |
| ES2060949T3 (es) | 1994-12-01 |
| US5510267A (en) | 1996-04-23 |
| AU5503790A (en) | 1990-11-15 |
| EP0398652A1 (de) | 1990-11-22 |
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