DE69708102D1 - Verfahren und reagenz zur überwachung des blutspiegels von antiplättchen-verbindungen - Google Patents

Verfahren und reagenz zur überwachung des blutspiegels von antiplättchen-verbindungen

Info

Publication number
DE69708102D1
DE69708102D1 DE69708102T DE69708102T DE69708102D1 DE 69708102 D1 DE69708102 D1 DE 69708102D1 DE 69708102 T DE69708102 T DE 69708102T DE 69708102 T DE69708102 T DE 69708102T DE 69708102 D1 DE69708102 D1 DE 69708102D1
Authority
DE
Germany
Prior art keywords
compounds
reagent
antiplatelet
antiplatch
monitoring
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69708102T
Other languages
English (en)
Other versions
DE69708102T2 (de
Inventor
P Carron
P Feigen
F Haas
M Meyer
D Page
Ann Pegg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GD Searle LLC filed Critical GD Searle LLC
Publication of DE69708102D1 publication Critical patent/DE69708102D1/de
Application granted granted Critical
Publication of DE69708102T2 publication Critical patent/DE69708102T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/808—Optical sensing apparatus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE69708102T 1996-05-15 1997-05-12 Verfahren und reagenz zur überwachung des blutspiegels von antiplättchen-verbindungen Expired - Fee Related DE69708102T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1771096P 1996-05-15 1996-05-15
PCT/US1997/007645 WO1997043650A1 (en) 1996-05-15 1997-05-12 Method and reagent for monitoring blood levels of antiplatelet compounds

Publications (2)

Publication Number Publication Date
DE69708102D1 true DE69708102D1 (de) 2001-12-13
DE69708102T2 DE69708102T2 (de) 2002-07-11

Family

ID=21784121

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69708102T Expired - Fee Related DE69708102T2 (de) 1996-05-15 1997-05-12 Verfahren und reagenz zur überwachung des blutspiegels von antiplättchen-verbindungen

Country Status (11)

Country Link
US (1) US6150114A (de)
EP (1) EP0912901B1 (de)
JP (1) JP2000510700A (de)
AT (1) ATE208505T1 (de)
AU (1) AU2997597A (de)
CA (1) CA2253402A1 (de)
DE (1) DE69708102T2 (de)
DK (1) DK0912901T3 (de)
ES (1) ES2166996T3 (de)
PT (1) PT912901E (de)
WO (1) WO1997043650A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6221672B1 (en) * 1996-04-30 2001-04-24 Medtronic, Inc. Method for determining platelet inhibitor response
AU1712700A (en) * 1998-11-18 2000-06-05 G.D. Searle & Co. Restoration of platelet aggregation by antibody administration after gpiib/iiia antagonist treatment
US6972296B2 (en) 1999-05-07 2005-12-06 Encysive Pharmaceuticals Inc. Carboxylic acid derivatives that inhibit the binding of integrins to their receptors
RU2263109C2 (ru) * 1999-05-07 2005-10-27 Тексэс Байотекнолоджи Копэрейшн ПРОИЗВОДНЫЕ КАРБОНОВЫХ КИСЛОТ (ВАРИАНТЫ), ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ И СПОСОБ СЕЛЕКТИВНОГО ИНГИБИРОВАНИЯ СВЯЗЫВАНИЯ α4β1 ИНТЕГРИНА У МЛЕКОПИТАЮЩЕГО
CA2566411A1 (en) * 2004-05-11 2005-11-24 Heptest Laboratories, Inc. Compositions, kit and one-step method for monitoring compounds having anti-factor xa and/or anti factor iia activities

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4393040A (en) * 1981-03-24 1983-07-12 Lopapa Institute, Inc. In-vitro diagnostic method for detection of acetylsalicylic acid ingestion
US4871677A (en) * 1985-02-25 1989-10-03 Hemotec, Inc. Method of collecting and analyzing a sample of blood when monitoring heparin therapy
US5182260A (en) * 1989-01-27 1993-01-26 Biogen, Inc. Dna sequences encoding snake venom inhibitors of platelet activation processes for producing those inhibitors and compositions using them
US5290680A (en) * 1991-06-28 1994-03-01 Takeda Chemical Industries, Ltd. Monoclonal antibody, method of production thereof and use thereof
US5239113A (en) * 1991-10-15 1993-08-24 Monsanto Company Substituted β-amino acid derivatives useful as platelet aggregation inhibitors and intermediates thereof
EP0691953B1 (de) * 1993-03-31 2000-08-02 G.D. Searle & Co. 1-amdinophenyl-pyrrolidone/piperidinone als blutblättchen-aggregations inhibitoren
US5662671A (en) * 1996-07-17 1997-09-02 Embol-X, Inc. Atherectomy device having trapping and excising means for removal of plaque from the aorta and other arteries

Also Published As

Publication number Publication date
PT912901E (pt) 2002-04-29
US6150114A (en) 2000-11-21
ES2166996T3 (es) 2002-05-01
EP0912901B1 (de) 2001-11-07
JP2000510700A (ja) 2000-08-22
WO1997043650A1 (en) 1997-11-20
DE69708102T2 (de) 2002-07-11
AU2997597A (en) 1997-12-05
ATE208505T1 (de) 2001-11-15
CA2253402A1 (en) 1997-11-20
EP0912901A1 (de) 1999-05-06
DK0912901T3 (da) 2002-02-25

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee