DE69419192D1 - Methode zur Bestimmung von Hämoglobinaddukten - Google Patents

Methode zur Bestimmung von Hämoglobinaddukten

Info

Publication number
DE69419192D1
DE69419192D1 DE69419192T DE69419192T DE69419192D1 DE 69419192 D1 DE69419192 D1 DE 69419192D1 DE 69419192 T DE69419192 T DE 69419192T DE 69419192 T DE69419192 T DE 69419192T DE 69419192 D1 DE69419192 D1 DE 69419192D1
Authority
DE
Germany
Prior art keywords
hemoglobin
blood sample
determination
adduct
concentration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69419192T
Other languages
English (en)
Other versions
DE69419192T2 (de
Inventor
Kin-Fai Yip
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics Inc
Original Assignee
Bayer AG
Bayer Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG, Bayer Corp filed Critical Bayer AG
Publication of DE69419192D1 publication Critical patent/DE69419192D1/de
Application granted granted Critical
Publication of DE69419192T2 publication Critical patent/DE69419192T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721—Haemoglobin
    • G01N33/723—Glycosylated haemoglobin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/105831—Protein or peptide standard or control [e.g., hemoglobin, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE69419192T 1993-04-02 1994-03-21 Methode zur Bestimmung von Hämoglobinaddukten Expired - Lifetime DE69419192T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4147193A 1993-04-02 1993-04-02
US08/077,546 US6043043A (en) 1993-04-02 1993-06-18 Method for the determination of hemoglobin adducts

Publications (2)

Publication Number Publication Date
DE69419192D1 true DE69419192D1 (de) 1999-07-29
DE69419192T2 DE69419192T2 (de) 1999-11-04

Family

ID=26718171

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69419192T Expired - Lifetime DE69419192T2 (de) 1993-04-02 1994-03-21 Methode zur Bestimmung von Hämoglobinaddukten

Country Status (9)

Country Link
US (1) US6043043A (de)
EP (1) EP0618449B1 (de)
JP (1) JP3331251B2 (de)
AT (1) ATE181599T1 (de)
DE (1) DE69419192T2 (de)
DK (1) DK0618449T3 (de)
ES (1) ES2132272T3 (de)
FI (1) FI109557B (de)
NZ (1) NZ260084A (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7459127B2 (en) * 2002-02-26 2008-12-02 Siemens Healthcare Diagnostics Inc. Method and apparatus for precise transfer and manipulation of fluids by centrifugal and/or capillary forces
CA2494322C (en) * 2002-08-06 2012-05-22 Metabolix Inc. Polymer extraction methods
AU2003298412A1 (en) * 2002-09-03 2004-03-29 Zeptosens Ag Analytical platform and identification method
US7125711B2 (en) * 2002-12-19 2006-10-24 Bayer Healthcare Llc Method and apparatus for splitting of specimens into multiple channels of a microfluidic device
US7094354B2 (en) * 2002-12-19 2006-08-22 Bayer Healthcare Llc Method and apparatus for separation of particles in a microfluidic device
US7435381B2 (en) * 2003-05-29 2008-10-14 Siemens Healthcare Diagnostics Inc. Packaging of microfluidic devices
US20040265172A1 (en) * 2003-06-27 2004-12-30 Pugia Michael J. Method and apparatus for entry and storage of specimens into a microfluidic device
US20080257754A1 (en) * 2003-06-27 2008-10-23 Pugia Michael J Method and apparatus for entry of specimens into a microfluidic device
US20040265171A1 (en) * 2003-06-27 2004-12-30 Pugia Michael J. Method for uniform application of fluid into a reactive reagent area
US7347617B2 (en) * 2003-08-19 2008-03-25 Siemens Healthcare Diagnostics Inc. Mixing in microfluidic devices
CA2510277C (en) * 2003-09-23 2012-07-24 Epinex Diagnostics, Inc. Rapid test for glycated albumin
US7150995B2 (en) * 2004-01-16 2006-12-19 Metrika, Inc. Methods and systems for point of care bodily fluid analysis
WO2006112339A1 (ja) * 2005-04-14 2006-10-26 Matsushita Electric Industrial Co., Ltd. ヘモグロビン誘導体の測定方法、それに用いる試薬組成物、測定キット、分析デバイス、及び分析システム
EP2211175B1 (de) * 2007-10-30 2012-04-25 Panasonic Corporation Verfahren zur messung von hämoglobin und hämoglobin-derivat sowie messkit
JP5563470B2 (ja) * 2007-11-20 2014-07-30 シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレーテッド 糖化ヘモグロビン検出法
US20100167306A1 (en) * 2008-12-26 2010-07-01 Henry John Smith Rapid test for glycated albumin in saliva
US8603828B2 (en) 2009-11-18 2013-12-10 Bio-Rad Laboratories, Inc. Multiplex immunoassays for hemoglobin, hemoglobin variants, and glycated forms
CN109073646A (zh) * 2016-05-13 2018-12-21 荣研化学株式会社 求取待测物在对比物中所占比例的方法、程序、存储介质及装置
JP7209804B2 (ja) * 2018-07-13 2023-01-20 シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレイテッド 免疫測定法試薬の不完全な分散を原因とする異常な結果の検出方法
JP7182724B2 (ja) * 2019-02-15 2022-12-02 シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレイテッド 患者の液体試験サンプル中の糖化ヘモグロビンパーセントを決定するためのキャリブレーターおよびコントロール
EP3973253A4 (de) * 2019-05-20 2022-08-10 Siemens Healthcare Diagnostics, Inc. Verfahren zum nachweis von aberranten ergebnissen durch unvollständige abgabe eines polyhaptenreagenzes in immunoassays
US20220260596A1 (en) * 2019-06-27 2022-08-18 Case Western Reserve University Compositions and methods for blood anemia detection

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4658022A (en) * 1985-08-08 1987-04-14 Molecular Diagnostics, Inc. Binding of antibody reagents to denatured protein analytes
US4837170A (en) * 1986-01-20 1989-06-06 Otsuka Pharmaceutical Co., Ltd. Monoclonal antibody, measuring method of glucosylated protein by utilizing the monoclonal antibody, and kit therefor
US4835097A (en) * 1986-10-15 1989-05-30 Saunders Alexander M Method for ascertaining the history of a condition of the body from a single blood sample
US4970171A (en) * 1987-11-09 1990-11-13 Miles Inc. Denaturant reagents for convenient determination of hemoglobin derivatives in blood

Also Published As

Publication number Publication date
FI941522A0 (fi) 1994-03-31
FI941522A (fi) 1994-10-03
EP0618449A1 (de) 1994-10-05
JPH06308122A (ja) 1994-11-04
US6043043A (en) 2000-03-28
EP0618449B1 (de) 1999-06-23
JP3331251B2 (ja) 2002-10-07
ES2132272T3 (es) 1999-08-16
FI109557B (fi) 2002-08-30
ATE181599T1 (de) 1999-07-15
DK0618449T3 (da) 1999-12-06
NZ260084A (en) 1995-02-24
DE69419192T2 (de) 1999-11-04

Similar Documents

Publication Publication Date Title
DE69419192D1 (de) Methode zur Bestimmung von Hämoglobinaddukten
DE59310046D1 (de) Immunologische Methode zur Bestimmung von HbAIc
ATE97495T1 (de) Bestimmung mit affinitaetssubstanzen und hplcschritt.
DE59710488D1 (de) Vorrichtung und Verwendung einer Vorrichtung zur Bestimmung der Konzentration von Hämoglobinderivaten in einer unverdünnten, unhämolysierten Vollblutprobe
EP0871026A3 (de) Spektrophometrische Analyse
DE3382767D1 (de) Ein Verfahren zur Herstellung eines Antikörpers, der zur Bestimmung der Anwesenheit eines menschlichen Oncogens befähigt ist.
DE3788762D1 (de) Verfahren zur Bestimmung von physiologisch wirksamen Substanzen.
DE59208032D1 (de) Funktioneller Test und Reagenz zur Bestimmung von Fibrinogen
BR8707578A (pt) Aparelho e processo para medir nao invasivamente a concentracao de um constituinte sanguineo
ATE12318T1 (de) Verfahren und reagenz zur bestimmung von glykosiliertem haemoglobin.
ATE151532T1 (de) Quantitative bestimmung von mustern durch kapillare elektrophorese
ATE113663T1 (de) Reagenz zum nachweis und zur quantitativen bestimmung von leukozyten in biologischen flüssigkeiten und verfahren zu seiner verwendung.
DE3765147D1 (de) Verfahren und reagenz zur bestimmung von gesamt-bilirubin.
DE69026006D1 (de) Enzymatisches Verfahren zur Bestimmung der Analyt-Konzentration
ATE64470T1 (de) Verfahren und zusammensetzungen zur bestimmung von heparin.
DE60003106D1 (de) Reagenz zur Bestimmung von Leukozyten und zur Messung von Hämoglobin in einer Blutprobe
ATE147861T1 (de) Funktioneller test zur bestimmung der protein s- aktivität
DE69922213D1 (de) Verfahren und testsatz zur bestimmung der analytkonzentration im blut
ATE208505T1 (de) Verfahren und reagenz zur überwachung des blutspiegels von antiplättchen-verbindungen
DE69614374D1 (de) Verfahren zur spektralanalyse von inhomogenen proben
CA2118752A1 (en) Method for the Determination of Hemoglobin Adducts
DE59202364D1 (de) Verfahren zur quantitativen Bestimmung von krankheitsspezifischen Antigenen und Vorrichtung zur Durchführung des Verfahrens.
ATE195182T1 (de) Überwachung von patienten mit lungenkrebs durch messung von nca 50/90 im blut
ATE57022T1 (de) Verfahren zur bestimmung von parathormon.
DE69128193D1 (de) Verfahren zur bestimmung von gesamtem kalzium unter verwendung eines verdünnungsmittels

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: SIEMENS HEALTHCARE DIAGNOSTICS INC. (N.D.GES.D, US

8328 Change in the person/name/address of the agent

Representative=s name: MAIER, D., DIPL.-ING. UNIV., PAT.-ASS., 81739 MUEN