ATE97495T1 - Bestimmung mit affinitaetssubstanzen und hplcschritt. - Google Patents

Bestimmung mit affinitaetssubstanzen und hplcschritt.

Info

Publication number
ATE97495T1
ATE97495T1 AT89107393T AT89107393T ATE97495T1 AT E97495 T1 ATE97495 T1 AT E97495T1 AT 89107393 T AT89107393 T AT 89107393T AT 89107393 T AT89107393 T AT 89107393T AT E97495 T1 ATE97495 T1 AT E97495T1
Authority
AT
Austria
Prior art keywords
determination
affinity substances
hplc step
affinity
analyte
Prior art date
Application number
AT89107393T
Other languages
English (en)
Inventor
Shinji Satomura
Kenji Nakamura
Tokuji Ikenaka
Kaoru Omichi
Original Assignee
Wako Pure Chem Ind Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wako Pure Chem Ind Ltd filed Critical Wako Pure Chem Ind Ltd
Application granted granted Critical
Publication of ATE97495T1 publication Critical patent/ATE97495T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • G01N33/538Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody by sorbent column, particles or resin strip, i.e. sorbent materials
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N2030/022Column chromatography characterised by the kind of separation mechanism
    • G01N2030/027Liquid chromatography
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/04Preparation or injection of sample to be analysed
    • G01N30/06Preparation
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/803Physical recovery methods, e.g. chromatography, grinding
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/971Capture of complex after antigen-antibody reaction
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/811Test for named disease, body condition or organ function
    • Y10S436/812Infectious mononucleosis
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/824Immunological separation techniques

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Peptides Or Proteins (AREA)
AT89107393T 1988-04-25 1989-04-24 Bestimmung mit affinitaetssubstanzen und hplcschritt. ATE97495T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP10179888 1988-04-25
EP89107393A EP0357869B1 (de) 1988-04-25 1989-04-24 Bestimmung mit Affinitätssubstanzen und HPLC-Schritt

Publications (1)

Publication Number Publication Date
ATE97495T1 true ATE97495T1 (de) 1993-12-15

Family

ID=14310167

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89107393T ATE97495T1 (de) 1988-04-25 1989-04-24 Bestimmung mit affinitaetssubstanzen und hplcschritt.

Country Status (5)

Country Link
US (1) US5545530A (de)
EP (1) EP0357869B1 (de)
JP (1) JPH0734015B2 (de)
AT (1) ATE97495T1 (de)
DE (1) DE68910758T2 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE131933T1 (de) * 1990-01-09 1996-01-15 Wako Pure Chem Ind Ltd Verfahren zur abtrennung und messung von spurbestandteilen
JP2994739B2 (ja) * 1990-11-29 1999-12-27 和光純薬工業株式会社 微量成分の迅速測定方法
US5571729A (en) * 1992-06-17 1996-11-05 Wako Pure Chemical Industries, Ltd. Process for separating complex
DE69422692T2 (de) * 1993-11-16 2000-07-06 Wako Pure Chemical Industries, Ltd. Verfahren zum Trennen und Messen von Glykoprotein
CA2181109A1 (en) 1995-07-18 1997-01-19 Nobuko Imajo Polypeptide and process for measuring living body components using the same
EP0794434B1 (de) * 1995-09-22 2005-04-06 Asahi Denka Kogyo Kabushiki Kaisha Verfahren zur analyse von allergenen
US6005256A (en) * 1998-02-12 1999-12-21 Raytheon Company Method and apparatus for performing cell analysis based on simultaneous multiple marker emissions from neoplasia (CASMMEN)
US6471968B1 (en) 2000-05-12 2002-10-29 Regents Of The University Of Michigan Multifunctional nanodevice platform
ES2349949T3 (es) 2001-04-04 2011-01-13 Wako Pure Chemical Industries, Ltd. Electrofóresis con marcador de adn bicatenario.
US7442313B2 (en) * 2003-08-27 2008-10-28 Thinkvillage-Kerfoot, Llc Environmental remediation method and system
US7569140B2 (en) * 2005-11-10 2009-08-04 Thinkvillage-Kerfoot, Llc Directional spargewell system
US8771507B2 (en) 2003-12-24 2014-07-08 Thinkvillage-Kerfoot, Llc Directional microporous diffuser and directional sparging
US7621696B2 (en) * 2006-07-12 2009-11-24 Thinkvillage-Kerfoot, Llc Directional microporous diffuser and directional sparging
US8470315B2 (en) 2004-04-13 2013-06-25 Quintessence Biosciences, Inc. Non-natural ribonuclease conjugates as cytotoxic agents
US20090104119A1 (en) * 2004-08-25 2009-04-23 Majoros Istvan J Dendrimer Based Compositions And Methods Of Using The Same
US20070041934A1 (en) * 2005-08-12 2007-02-22 Regents Of The University Of Michigan Dendrimer based compositions and methods of using the same
EP2044097A4 (de) * 2006-06-23 2010-10-06 Quintessence Biosciences Inc Modifizierte ribonukleasen
WO2008010991A2 (en) 2006-07-17 2008-01-24 Quintessence Biosciences, Inc. Methods and compositions for the treatment of cancer
CA2684725A1 (en) * 2007-04-19 2009-01-15 The Regents Of The University Of Michigan Dendrimer based compositions and methods of using the same
US9175015B2 (en) * 2007-08-22 2015-11-03 Colorado School Of Mines Gold nanoparticle conjugates and uses thereof
EP2205271B1 (de) * 2007-10-08 2014-05-21 Quintessence Biosciences, Inc. Zusammensetzungen und verfahren für therapien auf ribonukleasebasis
WO2009151687A2 (en) 2008-03-12 2009-12-17 The Regents Of The University Of Michigan Dendrimer conjugates
WO2010096464A1 (en) 2009-02-18 2010-08-26 Boyes Stephen G Gold/lanthanide nanoparticle conjugates and uses thereof
US8889635B2 (en) 2008-09-30 2014-11-18 The Regents Of The University Of Michigan Dendrimer conjugates
BRPI0920743A2 (pt) 2008-10-01 2016-09-20 Quintessence Biosciences Inc ribonucleases terapeuticas
AU2009302217A1 (en) 2008-10-09 2010-04-15 Northeastern University Multifunctional self-assembling polymeric nanosystems
US9017644B2 (en) 2008-11-07 2015-04-28 The Regents Of The University Of Michigan Methods of treating autoimmune disorders and/or inflammatory disorders
EP2488172A4 (de) 2009-10-13 2014-08-13 Univ Michigan Dendrimerzusammensetzung und verfahren zu ihrer synthese
US8912323B2 (en) 2009-10-30 2014-12-16 The Regents Of The University Of Michigan Multifunctional small molecules
JP5960707B2 (ja) * 2010-10-18 2016-08-02 ネステク ソシエテ アノニム 抗薬物抗体アイソタイプを決定するための方法
US9402911B2 (en) 2011-12-08 2016-08-02 The Regents Of The University Of Michigan Multifunctional small molecules

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL42105A (en) * 1973-04-25 1976-08-31 Yissum Res Dev Co Process for determination of triiodothyronine
IL51224A (en) * 1976-11-19 1979-09-30 Ames Yissum Ltd Assay method for the quanititative determination of a hapten in aqueous solution
US4145406A (en) * 1977-04-11 1979-03-20 Miles Laboratories, Inc. Specific binding - adsorbent assay method and test means
US4235869A (en) * 1978-05-16 1980-11-25 Syva Company Assay employing a labeled Fab-fragment ligand complex
US4371515A (en) * 1978-12-26 1983-02-01 E-Y Laboratories, Inc. Method for forming an isolated lectin-immunological conjugate
US4347058A (en) * 1980-09-15 1982-08-31 Beckman Instruments, Inc. Thyroid polarization fluoroimmunoassay
EP0073593A1 (de) * 1981-09-01 1983-03-09 E.I. Du Pont De Nemours And Company Grössendiskriminierende heterogene Immunzusammensetzung
US4496654A (en) * 1983-04-08 1985-01-29 Quidel Detection of HCG with solid phase support having avidin coating
DE3342627A1 (de) * 1983-11-25 1985-06-05 Boehringer Mannheim Gmbh, 6800 Mannheim Immunchemischer schnelltest
JPH0610678B2 (ja) * 1984-11-05 1994-02-09 オリンパス光学工業株式会社 免疫学的分析方法
JPS61120058A (ja) * 1984-11-16 1986-06-07 Hitachi Ltd 目的成分の分析方法及びその装置
US4670381A (en) * 1985-07-19 1987-06-02 Eastman Kodak Company Heterogeneous immunoassay utilizing horizontal separation in an analytical element

Also Published As

Publication number Publication date
DE68910758T2 (de) 1994-05-26
JPH0734015B2 (ja) 1995-04-12
JPH0228557A (ja) 1990-01-30
EP0357869A1 (de) 1990-03-14
DE68910758D1 (de) 1993-12-23
EP0357869B1 (de) 1993-11-18
US5545530A (en) 1996-08-13

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee