ATE228657T1 - Verfahren zum testen von immunosuppressoren - Google Patents
Verfahren zum testen von immunosuppressorenInfo
- Publication number
- ATE228657T1 ATE228657T1 AT95910762T AT95910762T ATE228657T1 AT E228657 T1 ATE228657 T1 AT E228657T1 AT 95910762 T AT95910762 T AT 95910762T AT 95910762 T AT95910762 T AT 95910762T AT E228657 T1 ATE228657 T1 AT E228657T1
- Authority
- AT
- Austria
- Prior art keywords
- immunosuppressant
- inhibiting
- immunosuppressors
- testing
- calcineulin
- Prior art date
Links
- 229960003444 immunosuppressant agent Drugs 0.000 abstract 3
- 230000001861 immunosuppressant effect Effects 0.000 abstract 3
- 239000003018 immunosuppressive agent Substances 0.000 abstract 3
- 230000002401 inhibitory effect Effects 0.000 abstract 3
- 102000004631 Calcineurin Human genes 0.000 abstract 2
- 108010042955 Calcineurin Proteins 0.000 abstract 2
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 abstract 1
- 102000000584 Calmodulin Human genes 0.000 abstract 1
- 108010041952 Calmodulin Proteins 0.000 abstract 1
- 229930105110 Cyclosporin A Natural products 0.000 abstract 1
- PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 abstract 1
- 108010036949 Cyclosporine Proteins 0.000 abstract 1
- 102000000521 Immunophilins Human genes 0.000 abstract 1
- 108010016648 Immunophilins Proteins 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 229910001424 calcium ion Inorganic materials 0.000 abstract 1
- 229960001265 ciclosporin Drugs 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
- G01N33/9493—Immunosupressants
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Compounds Of Unknown Constitution (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3953494 | 1994-03-10 | ||
| PCT/JP1995/000372 WO1995024645A1 (fr) | 1994-03-10 | 1995-03-08 | Procede de dosage des immunosuppresseurs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE228657T1 true ATE228657T1 (de) | 2002-12-15 |
Family
ID=12555720
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95910762T ATE228657T1 (de) | 1994-03-10 | 1995-03-08 | Verfahren zum testen von immunosuppressoren |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6338946B1 (de) |
| EP (1) | EP0750193B1 (de) |
| JP (1) | JP3551431B2 (de) |
| CN (1) | CN1147853A (de) |
| AT (1) | ATE228657T1 (de) |
| AU (1) | AU686762B2 (de) |
| CA (1) | CA2185105A1 (de) |
| DE (1) | DE69528968T2 (de) |
| MX (1) | MX9603838A (de) |
| NZ (1) | NZ281717A (de) |
| WO (1) | WO1995024645A1 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0976823A1 (de) * | 1998-07-22 | 2000-02-02 | Helge Dr. Völkel | Rekombinantes Expressions System und Hoch-Durchsatz BioAssay für die therapeutische Anwendung von Calcineurin-A-Alpha, Calcineurin-A-Beta, Calcineurin-A-Gamma, Calcineurin-B und Copper/Zinc-Superoxide Dismutase bzw. zur Identifizierung von Pharmazeutika |
| US7186518B2 (en) * | 2003-11-21 | 2007-03-06 | Dade Behring Inc. | Method and composition useful for determining FK 506 |
| DE102004003362A1 (de) * | 2004-01-22 | 2005-08-11 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Verfahren zur Identifizierung und Herstellung von Effektoren Calmodulin-abhängiger Peptidyl-Prolyl cis/trans Isomerasen |
| MX2007012447A (es) | 2005-04-06 | 2007-10-19 | Abbott Lab | Metodos para medir complejos inmunosupresores tacrolimus, sirolimus y ciclosporina a en una muestra de sangre. |
| EP1810675A1 (de) | 2006-01-18 | 2007-07-25 | Institut Curie | Methode zur Behandlung der Huntington'schen Krankheit durch Hemmung der Dephosphorylierung der S421 |
| US7642338B2 (en) | 2006-06-20 | 2010-01-05 | Siemens Healthcare Diagnostics Inc. | Tacrolimus standard and methods of using same |
| US20080081379A1 (en) * | 2006-07-13 | 2008-04-03 | Sigler Gerald F | Homogeneous double receptor agglutination assay for immunosuppressant drugs |
| US20110039789A1 (en) * | 2009-08-14 | 2011-02-17 | Institut Curie | Use of Huntingtin Protein for the Diagnosis and the Treatment of Cancer |
| BR112013010952B1 (pt) | 2010-10-22 | 2020-08-25 | T2 Biosystems, Inc. | métodos para detectar a presença de um analito de ácido nucleico e uma espécie de candida em uma amostra líquida, para detectar a presença de um patógeno, um vírus e um ácido nucleico alvo em uma amostra de sangue total, e para amplificação de um ácido nucleico de patógeno alvo em uma amostra de sangue total, bem como sistema para a detecção de um ou mais analitos e cartucho removível dimensionado para facilitar inserção e remoção de um sistema |
| US8563298B2 (en) | 2010-10-22 | 2013-10-22 | T2 Biosystems, Inc. | NMR systems and methods for the rapid detection of analytes |
| US8409807B2 (en) | 2010-10-22 | 2013-04-02 | T2 Biosystems, Inc. | NMR systems and methods for the rapid detection of analytes |
| EP2839038B1 (de) | 2012-04-20 | 2019-01-16 | T2 Biosystems, Inc. | Zusammensetzungen und verfahren für den nachweis einer candida-spezies |
| CN104164444A (zh) * | 2014-07-31 | 2014-11-26 | 宜昌美光硅谷生命科技有限公司 | 一种融合蛋白质、制备方法及其应用 |
| CN104749009B (zh) | 2015-03-30 | 2018-05-04 | 上海云泽生物科技有限公司 | 用于免疫分析的免疫抑制剂药物提取试剂 |
| WO2017127731A1 (en) | 2016-01-21 | 2017-07-27 | T2 Biosystems, Inc. | Nmr methods and systems for the rapid detection of bacteria |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5362629A (en) | 1991-08-05 | 1994-11-08 | President And Fellows Of Harvard College | Detection of immunosuppressants |
| US5457182A (en) | 1994-02-15 | 1995-10-10 | Merck & Co., Inc. | FK-506 cytosolic binding protein, FKBP12.6 |
| US5639852A (en) | 1994-09-01 | 1997-06-17 | Wisconsin Alumni Research Foundation | Immunostimulatory agents |
-
1995
- 1995-03-08 JP JP52335595A patent/JP3551431B2/ja not_active Expired - Fee Related
- 1995-03-08 CN CN95192949.6A patent/CN1147853A/zh active Pending
- 1995-03-08 MX MX9603838A patent/MX9603838A/es unknown
- 1995-03-08 DE DE69528968T patent/DE69528968T2/de not_active Expired - Fee Related
- 1995-03-08 AU AU18617/95A patent/AU686762B2/en not_active Ceased
- 1995-03-08 WO PCT/JP1995/000372 patent/WO1995024645A1/ja active IP Right Grant
- 1995-03-08 AT AT95910762T patent/ATE228657T1/de not_active IP Right Cessation
- 1995-03-08 EP EP95910762A patent/EP0750193B1/de not_active Expired - Lifetime
- 1995-03-08 CA CA002185105A patent/CA2185105A1/en not_active Abandoned
- 1995-03-08 NZ NZ281717A patent/NZ281717A/en unknown
-
1999
- 1999-12-09 US US09/457,395 patent/US6338946B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2185105A1 (en) | 1995-09-14 |
| AU1861795A (en) | 1995-09-25 |
| CN1147853A (zh) | 1997-04-16 |
| AU686762B2 (en) | 1998-02-12 |
| US6338946B1 (en) | 2002-01-15 |
| EP0750193A1 (de) | 1996-12-27 |
| NZ281717A (en) | 1997-03-24 |
| WO1995024645A1 (fr) | 1995-09-14 |
| DE69528968D1 (de) | 2003-01-09 |
| EP0750193A4 (de) | 1998-06-10 |
| EP0750193B1 (de) | 2002-11-27 |
| MX9603838A (es) | 1997-03-29 |
| JP3551431B2 (ja) | 2004-08-04 |
| DE69528968T2 (de) | 2003-03-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |