ATE108794T1 - Therapeutische nucleoside und deren herstellung. - Google Patents

Therapeutische nucleoside und deren herstellung.

Info

Publication number
ATE108794T1
ATE108794T1 AT86303662T AT86303662T ATE108794T1 AT E108794 T1 ATE108794 T1 AT E108794T1 AT 86303662 T AT86303662 T AT 86303662T AT 86303662 T AT86303662 T AT 86303662T AT E108794 T1 ATE108794 T1 AT E108794T1
Authority
AT
Austria
Prior art keywords
production
therapeutic nucleosides
nucleosides
therapeutic
dideoxynucleosides
Prior art date
Application number
AT86303662T
Other languages
English (en)
Inventor
George Walter Koszalka
Thomas Anthony Krenitsky
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB858512330A external-priority patent/GB8512330D0/en
Priority claimed from GB868604239A external-priority patent/GB8604239D0/en
Application filed by Wellcome Found filed Critical Wellcome Found
Application granted granted Critical
Publication of ATE108794T1 publication Critical patent/ATE108794T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/10—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 3 and 7, e.g. theobromine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/36—Sulfur atom
    • C07D473/38—Sulfur atom attached in position 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT86303662T 1985-05-15 1986-05-14 Therapeutische nucleoside und deren herstellung. ATE108794T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB858512330A GB8512330D0 (en) 1985-05-15 1985-05-15 Antiviral compounds
GB868604239A GB8604239D0 (en) 1986-02-20 1986-02-20 Antiviral compounds

Publications (1)

Publication Number Publication Date
ATE108794T1 true ATE108794T1 (de) 1994-08-15

Family

ID=26289262

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86303662T ATE108794T1 (de) 1985-05-15 1986-05-14 Therapeutische nucleoside und deren herstellung.

Country Status (13)

Country Link
EP (1) EP0206497B1 (de)
JP (1) JPH07116042B2 (de)
AT (1) ATE108794T1 (de)
AU (2) AU591125B2 (de)
CA (1) CA1314875C (de)
DE (1) DE3689976T2 (de)
DK (1) DK224286A (de)
ES (1) ES8801303A1 (de)
FI (1) FI87783C (de)
GR (1) GR861255B (de)
HU (1) HU196607B (de)
NZ (1) NZ216172A (de)
PT (1) PT82580B (de)

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Also Published As

Publication number Publication date
JPH07116042B2 (ja) 1995-12-13
FI87783B (fi) 1992-11-13
DE3689976D1 (de) 1994-08-25
FI862011A0 (fi) 1986-05-14
CA1314875C (en) 1993-03-23
JPS61280500A (ja) 1986-12-11
DE3689976T2 (de) 1995-03-16
HU196607B (en) 1988-12-28
ES8801303A1 (es) 1987-12-16
PT82580B (pt) 1989-01-17
AU591125B2 (en) 1989-11-30
PT82580A (en) 1986-06-01
EP0206497B1 (de) 1994-07-20
GR861255B (en) 1986-09-16
EP0206497A2 (de) 1986-12-30
FI862011L (fi) 1986-11-16
AU622950B2 (en) 1992-04-30
FI87783C (fi) 1993-02-25
DK224286A (da) 1986-11-16
ES554967A0 (es) 1987-12-16
HUT41809A (en) 1987-05-28
EP0206497A3 (en) 1988-06-08
DK224286D0 (da) 1986-05-14
AU4544389A (en) 1990-05-17
AU5744086A (en) 1986-11-20
NZ216172A (en) 1989-08-29

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties