AT386411B - Verfahren zur herstellung von neuem kristallinem 7-d-alpha-amino-alpha-(3-chlor-4-hydroxyphenyl) acetamido)-3-methyl-3-cephem-4-carbonsaeuremonohydrat - Google Patents

Verfahren zur herstellung von neuem kristallinem 7-d-alpha-amino-alpha-(3-chlor-4-hydroxyphenyl) acetamido)-3-methyl-3-cephem-4-carbonsaeuremonohydrat

Info

Publication number
AT386411B
AT386411B AT0386384A AT386384A AT386411B AT 386411 B AT386411 B AT 386411B AT 0386384 A AT0386384 A AT 0386384A AT 386384 A AT386384 A AT 386384A AT 386411 B AT386411 B AT 386411B
Authority
AT
Austria
Prior art keywords
alpha
cephem
acetamido
hydroxyphenyl
chlorine
Prior art date
Application number
AT0386384A
Other languages
German (de)
English (en)
Other versions
ATA386384A (de
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of ATA386384A publication Critical patent/ATA386384A/de
Application granted granted Critical
Publication of AT386411B publication Critical patent/AT386411B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT0386384A 1983-12-06 1984-12-05 Verfahren zur herstellung von neuem kristallinem 7-d-alpha-amino-alpha-(3-chlor-4-hydroxyphenyl) acetamido)-3-methyl-3-cephem-4-carbonsaeuremonohydrat AT386411B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8319463A FR2555989B1 (fr) 1983-12-06 1983-12-06 Monohydrate de chlorocephadroxyle

Publications (2)

Publication Number Publication Date
ATA386384A ATA386384A (de) 1988-01-15
AT386411B true AT386411B (de) 1988-08-25

Family

ID=9294877

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0386384A AT386411B (de) 1983-12-06 1984-12-05 Verfahren zur herstellung von neuem kristallinem 7-d-alpha-amino-alpha-(3-chlor-4-hydroxyphenyl) acetamido)-3-methyl-3-cephem-4-carbonsaeuremonohydrat

Country Status (25)

Country Link
JP (1) JPH0794461B2 (xx)
KR (1) KR920001769B1 (xx)
AT (1) AT386411B (xx)
AU (1) AU567780B2 (xx)
BE (1) BE901218A (xx)
CA (1) CA1246545A (xx)
CH (1) CH662569A5 (xx)
CY (1) CY1559A (xx)
DE (1) DE3444367A1 (xx)
DK (1) DK579984A (xx)
ES (1) ES8605279A1 (xx)
FI (1) FI81104C (xx)
FR (1) FR2555989B1 (xx)
GB (1) GB2150931B (xx)
GR (1) GR81159B (xx)
HK (1) HK72590A (xx)
IE (1) IE57832B1 (xx)
IT (1) IT1177370B (xx)
LU (1) LU85670A1 (xx)
MY (1) MY102192A (xx)
NL (1) NL8403670A (xx)
SE (1) SE8406171L (xx)
SG (1) SG48890G (xx)
YU (1) YU45221B (xx)
ZA (1) ZA849415B (xx)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2505697A1 (fr) * 1981-05-12 1982-11-19 Humblot Bernard Unite perfectionnee de soudage electrique

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3489751A (en) * 1967-09-05 1970-01-13 Bristol Myers Co 7-amino-cephalosporanic and decephalosporanic acid derivatives
AT350183B (de) * 1976-04-27 1979-05-10 Bristol Myers Co Verfahren zur herstellung eines cephalosporin- derivates, dessen monohydrates, sowie dessen salzen

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US516047A (en) * 1894-03-06 Wire bed-bottom
US3781282A (en) * 1971-01-20 1973-12-25 W Garbrecht Cephalosporin process and product
YU39709B (en) * 1972-09-15 1985-04-30 Bristol Myers Co Process for producing cephalosporin
US3985741A (en) * 1972-09-15 1976-10-12 Bristol-Myers Company Production of p-hydroxycephalexin
DE2317179C2 (de) * 1973-04-05 1982-11-25 Bristol-Myers Co., 10154 New York, N.Y. Verfahren zur Herstellung der relativ wasserunlöslichen kristallinen Form von Cefalexinmonohydrat
JPS5356311A (en) * 1976-10-28 1978-05-22 Toyama Chem Co Ltd Cefalexin monohydrate having novel crystal form and process for preparationof the same
US4160863A (en) * 1977-04-07 1979-07-10 Bristol-Myers Company Process for the preparation of the crystalline monohydrate of 7-[D-α-aα-(p-hydroxyphenyl)acetamido]-3-methyl-3-cephem-4-carboxylic acid
US4600773A (en) * 1983-12-01 1986-07-15 Eli Lilly And Company Crystalline cephalexin hydrochloride monohydrate

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3489751A (en) * 1967-09-05 1970-01-13 Bristol Myers Co 7-amino-cephalosporanic and decephalosporanic acid derivatives
AT350183B (de) * 1976-04-27 1979-05-10 Bristol Myers Co Verfahren zur herstellung eines cephalosporin- derivates, dessen monohydrates, sowie dessen salzen

Also Published As

Publication number Publication date
YU207384A (en) 1987-12-31
GB2150931A (en) 1985-07-10
CA1246545A (en) 1988-12-13
YU45221B (en) 1992-05-28
DK579984A (da) 1985-06-07
ES538235A0 (es) 1986-03-16
FI81104C (fi) 1990-09-10
GB2150931B (en) 1987-07-29
DE3444367A1 (de) 1985-06-20
IE57832B1 (en) 1993-04-21
CY1559A (en) 1991-03-22
GR81159B (en) 1985-04-08
IT8423909A1 (it) 1986-06-05
JPH0794461B2 (ja) 1995-10-11
FR2555989A1 (fr) 1985-06-07
ATA386384A (de) 1988-01-15
SE8406171L (sv) 1985-06-07
FI844756A0 (fi) 1984-12-03
FR2555989B1 (fr) 1987-02-20
AU567780B2 (en) 1987-12-03
JPS60139695A (ja) 1985-07-24
FI844756L (fi) 1985-06-07
DE3444367C2 (xx) 1993-04-29
ES8605279A1 (es) 1986-03-16
FI81104B (fi) 1990-05-31
LU85670A1 (fr) 1985-09-12
AU3632184A (en) 1985-06-13
SG48890G (en) 1990-08-17
BE901218A (fr) 1985-06-05
CH662569A5 (fr) 1987-10-15
SE8406171D0 (sv) 1984-12-05
NL8403670A (nl) 1985-07-01
IE843117L (en) 1985-06-06
IT8423909A0 (it) 1984-12-05
IT1177370B (it) 1987-08-26
KR850004494A (ko) 1985-07-15
HK72590A (en) 1990-09-21
DK579984D0 (da) 1984-12-05
KR920001769B1 (ko) 1992-03-02
ZA849415B (en) 1985-07-31
MY102192A (en) 1992-04-30
GB8430753D0 (en) 1985-01-16

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee
ELJ Ceased due to non-payment of the annual fee