AT373893B - Verfahren zur herstellung der neuen kristallinen 1,1-dioxopenicillanoyloxymethyl-6-(d-alpha-amin -alpha-phenylacetamido)-penicillanat-tosylat -hydrate - Google Patents

Verfahren zur herstellung der neuen kristallinen 1,1-dioxopenicillanoyloxymethyl-6-(d-alpha-amin -alpha-phenylacetamido)-penicillanat-tosylat -hydrate

Info

Publication number
AT373893B
AT373893B AT0447781A AT447781A AT373893B AT 373893 B AT373893 B AT 373893B AT 0447781 A AT0447781 A AT 0447781A AT 447781 A AT447781 A AT 447781A AT 373893 B AT373893 B AT 373893B
Authority
AT
Austria
Prior art keywords
alpha
dioxopenicillanoyloxymethyl
penicillanate
crystallines
phenylacetamido
Prior art date
Application number
AT0447781A
Other languages
English (en)
Other versions
ATA447781A (de
Original Assignee
Leo Pharm Prod Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo Pharm Prod Ltd filed Critical Leo Pharm Prod Ltd
Publication of ATA447781A publication Critical patent/ATA447781A/de
Application granted granted Critical
Publication of AT373893B publication Critical patent/AT373893B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT0447781A 1980-10-31 1981-10-20 Verfahren zur herstellung der neuen kristallinen 1,1-dioxopenicillanoyloxymethyl-6-(d-alpha-amin -alpha-phenylacetamido)-penicillanat-tosylat -hydrate AT373893B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8035156 1980-10-31

Publications (2)

Publication Number Publication Date
ATA447781A ATA447781A (de) 1983-07-15
AT373893B true AT373893B (de) 1984-02-27

Family

ID=10517019

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0447781A AT373893B (de) 1980-10-31 1981-10-20 Verfahren zur herstellung der neuen kristallinen 1,1-dioxopenicillanoyloxymethyl-6-(d-alpha-amin -alpha-phenylacetamido)-penicillanat-tosylat -hydrate

Country Status (26)

Country Link
US (1) US4831025A (de)
JP (1) JPS57126493A (de)
KR (1) KR870001982B1 (de)
AT (1) AT373893B (de)
AU (1) AU543870B2 (de)
BE (1) BE890938A (de)
CA (1) CA1180696A (de)
CH (1) CH647527A5 (de)
DE (1) DE3143219A1 (de)
DK (1) DK154219C (de)
ES (1) ES8206531A1 (de)
FI (1) FI813331L (de)
FR (1) FR2493322B1 (de)
GB (1) GB2114969B (de)
GR (1) GR75369B (de)
IE (1) IE51640B1 (de)
IL (1) IL64009A (de)
IT (1) IT1193735B (de)
LU (1) LU83727A1 (de)
NL (1) NL8104938A (de)
NO (1) NO813683L (de)
NZ (1) NZ198622A (de)
PH (1) PH17820A (de)
PT (1) PT73913B (de)
SE (1) SE452322B (de)
ZA (1) ZA817091B (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0405316A2 (de) * 1989-06-20 1991-01-02 Yeong Sul Kim 1,1-Dioxopenicillanoyloxymethyl D-6-[alpha(methylenamino)-phenylacetamido]-penicillanat und Verfahren zu seiner Herstellung

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US4432987A (en) * 1982-04-23 1984-02-21 Pfizer Inc. Crystalline benzenesulfonate salts of sultamicillin
PH20068A (en) * 1982-12-06 1986-09-18 Pfizer Process and intermediates for sultamicillin and analogs
ES2161602B1 (es) * 1999-04-08 2003-02-16 Asturpharma S A Sintesis de 6-(d-alfa-(bencilidenaminofenilacetamido))penicilanato de 1,1-dioxopenicilanoiloximetilo y analogos. nuevos intermedios para la sintesis de sultamicilina.
US6638532B2 (en) 2000-02-24 2003-10-28 Advancis Pharmaceutical Corp. Tetracycline—doxycycline antibiotic composition
US6544555B2 (en) 2000-02-24 2003-04-08 Advancis Pharmaceutical Corp. Antibiotic product, use and formulation thereof
US6610328B2 (en) 2000-02-24 2003-08-26 Advancis Pharmaceutical Corp. Amoxicillin-clarithromycin antibiotic composition
US6627222B2 (en) 2000-02-24 2003-09-30 Advancis Pharmaceutical Corp. Amoxicillin-dicloxacillin antibiotic composition
US6565882B2 (en) 2000-02-24 2003-05-20 Advancis Pharmaceutical Corp Antibiotic composition with inhibitor
WO2001062229A1 (en) * 2000-02-24 2001-08-30 Advanced Pharma, Inc. Therapeutic product, use and formulation thereof
US6991807B2 (en) * 2000-02-24 2006-01-31 Advancis Pharmaceutical, Corp. Antibiotic composition
US6730320B2 (en) 2000-02-24 2004-05-04 Advancis Pharmaceutical Corp. Tetracycline antibiotic product, use and formulation thereof
US6632453B2 (en) 2000-02-24 2003-10-14 Advancis Pharmaceutical Corp. Ciprofoxacin-metronidazole antibiotic composition
US6623758B2 (en) 2000-02-24 2003-09-23 Advancis Pharmaceutical Corp. Cephalosporin-metronidazole antibiotic composition
US6663890B2 (en) 2000-02-24 2003-12-16 Advancis Pharmaceutical Corp. Metronidazole antibiotic product, use and formulation thereof
US6669948B2 (en) 2000-02-24 2003-12-30 Advancis Pharmaceutical Corp. Antibiotic product, use and formulation thereof
JP2003523372A (ja) * 2000-02-24 2003-08-05 アドバンシス ファーマシューティカル コーポレイション 抗生物質及び抗真菌剤組成物
US7025989B2 (en) * 2000-02-24 2006-04-11 Advancis Pharmaceutical Corp. Multiple-delayed released antibiotic product, use and formulation thereof
US6663891B2 (en) 2000-02-24 2003-12-16 Advancis Pharmaceutical Corp. Erythromyacin antibiotic product, use and formulation thereof
US6667057B2 (en) 2000-02-24 2003-12-23 Advancis Pharmaceutical Corp. Levofloxacin antibiotic product, use and formulation thereof
US6667042B2 (en) 2000-02-24 2003-12-23 Advancis Pharmaceutical Corp. Fluroquinilone antibiotic product, use and formulation thereof
US7074417B2 (en) * 2000-10-13 2006-07-11 Advancis Pharmaceutical Corporation Multiple-delayed release anti-viral product, use and formulation thereof
US6541014B2 (en) 2000-10-13 2003-04-01 Advancis Pharmaceutical Corp. Antiviral product, use and formulation thereof
US7105174B2 (en) * 2000-10-13 2006-09-12 Advancis Pharmaceutical Corporation Multiple-delayed release anti-neoplastic product, use and formulation thereof
US7157095B2 (en) * 2000-10-13 2007-01-02 Advancis Pharmaceutical Corporation Multiple-delayed release antifungal product, use and formulation thereof
US20020197314A1 (en) * 2001-02-23 2002-12-26 Rudnic Edward M. Anti-fungal composition
US20040114368A1 (en) * 2002-12-13 2004-06-17 Shyu Shing Jy Light device having rotatable or movable view
US20040265323A1 (en) * 2003-05-16 2004-12-30 Mccormick Beth A. Compositions comprising pathogen elicited epithelial chemoattractant (eicosanoid hepoxilin A3), inhibitors thereof and methods of use thereof
WO2005009365A2 (en) 2003-07-21 2005-02-03 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
WO2005009368A2 (en) 2003-07-21 2005-02-03 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
JP2006528185A (ja) 2003-07-21 2006-12-14 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
US8758820B2 (en) 2003-08-11 2014-06-24 Shionogi Inc. Robust pellet
CA2535398C (en) 2003-08-12 2013-11-12 Advancis Pharmaceuticals Corporation Antibiotic product, use and formulation thereof
AU2004270170B2 (en) 2003-08-29 2011-01-27 Shionogi, Inc. Antibiotic product, use and formulation thereof
CA2538064C (en) 2003-09-15 2013-12-17 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
AU2005269981A1 (en) 2004-07-02 2006-02-09 Bonck, John A Tablet for pulsed delivery
WO2007004239A1 (en) * 2005-07-06 2007-01-11 Morepen Laboratories Limited New polymorphic form of sultamicillin tosylate and a process therefor
US8778924B2 (en) 2006-12-04 2014-07-15 Shionogi Inc. Modified release amoxicillin products
US8357394B2 (en) 2005-12-08 2013-01-22 Shionogi Inc. Compositions and methods for improved efficacy of penicillin-type antibiotics
US8299052B2 (en) * 2006-05-05 2012-10-30 Shionogi Inc. Pharmaceutical compositions and methods for improved bacterial eradication
SI2874624T1 (sl) 2012-07-17 2020-02-28 Bayer New Zealand Limited Formulacije antibiotikov za injektiranje in postopek njihove uporabe
CN104507475B (zh) 2012-07-17 2019-03-22 拜耳新西兰有限公司 注射用抗生素制剂及其使用方法
US11116737B1 (en) 2020-04-10 2021-09-14 University Of Georgia Research Foundation, Inc. Methods of using probenecid for treatment of coronavirus infections

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1532222A (fr) * 1963-10-28 1968-07-12 Bristol Myers Co Procédé de préparation de dérivés de la pénicilline
IE49881B1 (en) * 1979-02-13 1986-01-08 Leo Pharm Prod Ltd B-lactam intermediates
KR830001903B1 (ko) * 1979-02-13 1983-09-19 레오 파마슈티칼 프로덕츠 리미티드 페니실란산유도체의 제조방법
US4244951A (en) * 1979-05-16 1981-01-13 Pfizer Inc. Bis-esters of methanediol with penicillins and penicillanic acid 1,1-dioxide
IE51516B1 (en) * 1980-10-06 1987-01-07 Leo Pharm Prod Ltd 1,1-dioxapenicillanoyloxymethyl 6-(d-alpha-amino-alpha-phenylacetamido)penicillanate napsylate

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0405316A2 (de) * 1989-06-20 1991-01-02 Yeong Sul Kim 1,1-Dioxopenicillanoyloxymethyl D-6-[alpha(methylenamino)-phenylacetamido]-penicillanat und Verfahren zu seiner Herstellung
EP0405316A3 (en) * 1989-06-20 1991-01-23 Yeong Sul Kim 1,1-dioxopenicillanoyloxymethyl d-6-(alpha(methyleneamino)-phenyl-acetamidol)-penicillanate and a process for the preparation thereof

Also Published As

Publication number Publication date
GR75369B (de) 1984-07-13
PT73913A (en) 1981-11-01
KR870001982B1 (ko) 1987-10-24
IT8168383A0 (it) 1981-10-23
GB2114969A (en) 1983-09-01
NL8104938A (nl) 1982-05-17
IE51640B1 (en) 1987-01-21
SE452322B (sv) 1987-11-23
AU543870B2 (en) 1985-05-09
PH17820A (en) 1985-01-07
DK154219C (da) 1989-03-20
LU83727A1 (fr) 1982-05-07
DK472181A (da) 1982-05-01
CA1180696A (en) 1985-01-08
DE3143219A1 (de) 1982-08-12
CH647527A5 (de) 1985-01-31
GB2114969B (en) 1985-02-20
FR2493322A1 (fr) 1982-05-07
KR830007671A (ko) 1983-11-04
ES506751A0 (es) 1982-08-16
DK154219B (da) 1988-10-24
AU7636581A (en) 1982-05-06
FI813331L (fi) 1982-05-01
BE890938A (fr) 1982-04-30
IL64009A0 (en) 1982-01-31
IT1193735B (it) 1988-08-24
JPH027957B2 (de) 1990-02-21
DE3143219C2 (de) 1990-05-17
US4831025A (en) 1989-05-16
IL64009A (en) 1984-09-30
ZA817091B (en) 1982-10-27
FR2493322B1 (fr) 1986-06-13
ATA447781A (de) 1983-07-15
SE8106404L (sv) 1982-05-01
IE812361L (en) 1982-04-30
ES8206531A1 (es) 1982-08-16
NZ198622A (en) 1985-07-12
PT73913B (en) 1984-05-29
JPS57126493A (en) 1982-08-06
NO813683L (no) 1982-05-03

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