AT372390B - Verfahren zur herstellung von neuen 4'-jodderivaten von anthracyclinglykosiden - Google Patents

Verfahren zur herstellung von neuen 4'-jodderivaten von anthracyclinglykosiden

Info

Publication number
AT372390B
AT372390B AT0150782A AT150782A AT372390B AT 372390 B AT372390 B AT 372390B AT 0150782 A AT0150782 A AT 0150782A AT 150782 A AT150782 A AT 150782A AT 372390 B AT372390 B AT 372390B
Authority
AT
Austria
Prior art keywords
anthracyclinglycosides
producing new
iodine derivatives
iodine
derivatives
Prior art date
Application number
AT0150782A
Other languages
English (en)
Other versions
ATA150782A (de
Inventor
Antonino Suarato
Sergio Penco
Federico Arcamone
Anna Maria Casazza
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of ATA150782A publication Critical patent/ATA150782A/de
Application granted granted Critical
Publication of AT372390B publication Critical patent/AT372390B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AT0150782A 1982-04-19 1982-04-19 Verfahren zur herstellung von neuen 4'-jodderivaten von anthracyclinglykosiden AT372390B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB08211258A GB2118540B (en) 1982-04-19 1982-04-19 Anthracycline glycosides

Publications (2)

Publication Number Publication Date
ATA150782A ATA150782A (de) 1983-02-15
AT372390B true AT372390B (de) 1983-09-26

Family

ID=10529772

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0150782A AT372390B (de) 1982-04-19 1982-04-19 Verfahren zur herstellung von neuen 4'-jodderivaten von anthracyclinglykosiden

Country Status (15)

Country Link
US (1) US4438105A (de)
JP (1) JPS58183698A (de)
AT (1) AT372390B (de)
AU (1) AU545483B2 (de)
BE (1) BE892943A (de)
CH (1) CH649559A5 (de)
CZ (1) CZ415191A3 (de)
DE (1) DE3214559C2 (de)
FR (1) FR2525225A1 (de)
GB (1) GB2118540B (de)
HK (1) HK74787A (de)
MY (1) MY103665A (de)
NL (1) NL187443C (de)
SE (1) SE453596B (de)
SG (1) SG34687G (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8321676D0 (en) * 1983-08-11 1983-09-14 Erba Farmitalia 4'-haloanthrocycline glycosides
GB8414619D0 (en) * 1984-06-08 1984-07-11 Erba Farmitalia Anthracyclines
GB8426672D0 (en) * 1984-10-22 1984-11-28 Erba Farmitalia Pharmaceutical compositions
DE3500017A1 (de) * 1985-01-02 1986-07-10 Farmitalia Carlo Erba S.p.A., Mailand/Milano 4'-haloanthracyclinester
GB2169286A (en) * 1985-01-05 1986-07-09 Erba Farmitalia 4'-Deoxy-4'-halodoxorubicin-14-esters
US5124317A (en) * 1985-08-02 1992-06-23 Farmitalia Carlo Erba S.P.A. Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
GB8519452D0 (en) * 1985-08-02 1985-09-11 Erba Farmitalia Injectable solutions
IE58981B1 (en) * 1985-10-15 1993-12-15 Vestar Inc Anthracycline antineoplastic agents encapsulated in phospholipid micellular particles
GB8701381D0 (en) * 1987-01-22 1987-02-25 Erba Farmitalia Antitumor agent
GB2218087B (en) * 1988-04-22 1991-01-30 Erba Carlo Spa 4-demethoxy-4'-deoxy-4'iodo anthracycline glycosides
AU601857B2 (en) * 1988-06-30 1990-09-20 Pharmacia & Upjohn S.P.A. A new antitumor agent obtained by microbial stereoselective reduction of 4'-deoxy-4'-iododoxorubicin
GB2238540B (en) * 1989-11-29 1993-09-29 Erba Carlo Spa 13-deoxy-4'-deoxy-4'-iodoanthracyclines
GB9019934D0 (en) * 1990-09-12 1990-10-24 Erba Carlo Spa 2-hydroxy-and 2-acyloxy-4-morpholinyl anthracyclines
GB9216962D0 (en) * 1992-08-11 1992-09-23 Erba Carlo Spa Therapeutically active naphthalenesulfonic-pyrrolecarboxamido derivatives
IL110289A (en) * 1993-08-06 1998-01-04 Policlinico San Matteo Istitut Pharmaceutical preparations containing 4-iodo-4-deoxydoxorubicin for the treatment of amyloidosis
US6355784B1 (en) 1998-06-12 2002-03-12 Waldemar Priebe Methods and compositions for the manufacture of halogenated anthracyclines with increased antitumor activity, other anthracyclines, halogenated sugars, and glycosyl donors
AU2343900A (en) * 1998-11-02 2000-05-22 Board Of Regents, The University Of Texas System Methods and compositions for the manufacture of highly potent anthracycline-based antitumor agents
US20040038904A1 (en) * 2002-05-21 2004-02-26 Angela Ogden Method of treating multiple sclerosis

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3803124A (en) 1968-04-12 1974-04-09 Farmaceutici It Soc Process for the preparation of adriamycin and adriamycinone and adriamycin derivatives
US4303785A (en) 1978-08-05 1981-12-01 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Antitumor anthracycline antibiotics
US4345070A (en) * 1980-09-29 1982-08-17 Farmitalia Carlo Erba S.P.A. Process for the preparation of 4'-deoxy-daunorubicin and 4'-deoxy-doxorubicin

Also Published As

Publication number Publication date
NL8201703A (nl) 1983-11-16
DE3214559C2 (de) 1986-05-15
FR2525225A1 (fr) 1983-10-21
AU545483B2 (en) 1985-07-18
ATA150782A (de) 1983-02-15
JPS6260395B2 (de) 1987-12-16
FR2525225B1 (de) 1985-02-15
BE892943A (fr) 1982-08-16
JPS58183698A (ja) 1983-10-26
GB2118540A (en) 1983-11-02
NL187443C (nl) 1991-10-01
SG34687G (en) 1987-07-17
SE453596B (sv) 1988-02-15
HK74787A (en) 1987-10-23
CH649559A5 (it) 1985-05-31
AU8297882A (en) 1983-10-27
US4438105A (en) 1984-03-20
DE3214559A1 (de) 1983-10-20
CZ415191A3 (en) 1993-05-12
GB2118540B (en) 1985-08-14
SE8202439L (sv) 1983-10-20
NL187443B (nl) 1991-05-01
MY103665A (en) 1993-08-28

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Legal Events

Date Code Title Description
EIH Change in the person of patent owner
EIH Change in the person of patent owner
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties
ELJ Ceased due to non-payment of the annual fee