AT371818B - Verfahren zur herstellung von tricyclischen pyrimidinderivaten und von deren salzen - Google Patents

Verfahren zur herstellung von tricyclischen pyrimidinderivaten und von deren salzen

Info

Publication number
AT371818B
AT371818B AT0597178A AT597178A AT371818B AT 371818 B AT371818 B AT 371818B AT 0597178 A AT0597178 A AT 0597178A AT 597178 A AT597178 A AT 597178A AT 371818 B AT371818 B AT 371818B
Authority
AT
Austria
Prior art keywords
salts
pyrimidine derivatives
tricyclic pyrimidine
producing tricyclic
producing
Prior art date
Application number
AT0597178A
Other languages
English (en)
Other versions
ATA597178A (de
Inventor
Istvan Dipl Ing Chem D Hermecz
Ferenc Fueloep
Zoltan Chem Ing Dr Meszaros
Gabor Dr Bernath
Jozsef Dr Knoll
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of ATA597178A publication Critical patent/ATA597178A/de
Application granted granted Critical
Publication of AT371818B publication Critical patent/AT371818B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT0597178A 1977-08-19 1978-08-17 Verfahren zur herstellung von tricyclischen pyrimidinderivaten und von deren salzen AT371818B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU77CI1766A HU182009B (en) 1977-08-19 1977-08-19 Process for producing substituted pirido-square bracket-1,2-a-square bracket closed-pyrimidines, pyrrolo-square bracket-1,2-a-square bracket closed-pyrimidines

Publications (2)

Publication Number Publication Date
ATA597178A ATA597178A (de) 1982-12-15
AT371818B true AT371818B (de) 1983-08-10

Family

ID=10994668

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0597178A AT371818B (de) 1977-08-19 1978-08-17 Verfahren zur herstellung von tricyclischen pyrimidinderivaten und von deren salzen

Country Status (21)

Country Link
US (1) US4220771A (de)
JP (1) JPS5459299A (de)
AT (1) AT371818B (de)
BE (1) BE869833A (de)
CA (1) CA1117525A (de)
CH (1) CH638207A5 (de)
CS (1) CS240351B1 (de)
DD (1) DD138902A5 (de)
DE (1) DE2836449A1 (de)
DK (1) DK157021C (de)
ES (1) ES473182A1 (de)
FI (1) FI67547C (de)
FR (1) FR2416893A1 (de)
GB (1) GB2003870B (de)
GR (1) GR65275B (de)
HU (1) HU182009B (de)
NL (1) NL7808571A (de)
PL (1) PL116688B1 (de)
SE (1) SE436279B (de)
SU (1) SU749365A3 (de)
YU (1) YU196578A (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4348396A (en) * 1978-01-23 1982-09-07 Hoffmann-La Roche Inc. Substituted 11-oxo-11H-pyrido[2,1-b]quinazolines and method of inhibiting allergic reactions with them
US4395549A (en) * 1981-10-02 1983-07-26 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. 6-Hydrazono-pyrido[2,1-b] quinazoline-11 ones
ES521739A0 (es) * 1982-04-29 1984-07-01 Erba Farmitalia Procedimiento para preparar derivados cicloalifaticos condensados de pirido(1,2-a)pirimidinas sustituidas.
HU191192B (en) * 1982-11-16 1987-01-28 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt,Hu Process for producing new azepino /1,2-a/ pyrimidine derivatives of bronchodilating activity and acid additional salts thereof and pharmaceiutical compositions containing them
EP0597956A1 (de) * 1991-07-29 1994-05-25 Warner-Lambert Company Chinazolin-derivate als acetylcholinesterase-inhibitoren
US5892917A (en) * 1995-09-27 1999-04-06 Microsoft Corporation System for log record and log expansion with inserted log records representing object request for specified object corresponding to cached object copies
CA2784830C (en) * 2009-12-18 2018-03-27 Sunovion Pharmaceuticals Inc. Compounds for treating disorders mediated by metabotropic glutamate receptor 5, and methods of use thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2992221A (en) * 1958-07-03 1961-07-11 Petersen Siegfried Polymethylene-oxoquinazolines and their production
DE1088968B (de) 1958-07-03 1960-09-15 Bayer Ag Verfahren zur Herstellung von mehrkernigen, heterocyclischen, einen 4-Oxo-3, 4-dihydro-pyrimidinring enthaltenden Verbindungen
US3271396A (en) * 1964-08-17 1966-09-06 Squibb & Sons Inc Pyrido-quinazoline derivatives
DE1803785A1 (de) * 1968-10-18 1970-06-04 Hoechst Ag Verfahren zur Herstellung von 1,2-disubstituierten 6-Oxo-1.4.5.6-tetrahydropyrimidinen
US3790573A (en) * 1971-11-11 1974-02-05 Smithkline Corp Imidazo and pyrimido(2,1-b)quinazolines
US3965100A (en) * 1975-02-26 1976-06-22 E. R. Squibb & Sons, Inc. 2,3-Dihydrocyclopenta[d]pyrido[1,2-a]pyrimidin-10(1H)-one and its derivatives
US4033961A (en) * 1975-10-07 1977-07-05 Warner-Lambert Company Pyrido[2-1-b]quinazolin-ones and their methods of preparation
DE2557425A1 (de) * 1975-12-19 1977-06-30 Boehringer Sohn Ingelheim Chinazolonderivate
JPH0297996A (ja) * 1988-10-05 1990-04-10 Toshiba Corp 画像データ変換回路

Also Published As

Publication number Publication date
SU749365A3 (ru) 1980-07-15
US4220771A (en) 1980-09-02
SE436279B (sv) 1984-11-26
GR65275B (en) 1980-07-31
FR2416893B1 (de) 1983-07-22
HU182009B (en) 1983-12-28
CS240351B1 (en) 1986-02-13
FI67547B (fi) 1984-12-31
DK367378A (da) 1979-02-20
DE2836449C2 (de) 1990-09-06
DD138902A5 (de) 1979-11-28
CH638207A5 (de) 1983-09-15
BE869833A (fr) 1978-12-18
SE7808771L (sv) 1979-02-20
NL7808571A (nl) 1979-02-21
DE2836449A1 (de) 1979-03-22
PL116688B1 (en) 1981-06-30
YU196578A (en) 1983-10-31
ES473182A1 (es) 1979-04-01
CA1117525A (en) 1982-02-02
FI782517A (fi) 1979-02-20
FI67547C (fi) 1985-04-10
PL209131A1 (pl) 1979-06-04
GB2003870A (en) 1979-03-21
ATA597178A (de) 1982-12-15
CS541878A1 (en) 1985-05-15
GB2003870B (en) 1982-07-21
JPS5459299A (en) 1979-05-12
DK157021C (da) 1990-04-02
FR2416893A1 (fr) 1979-09-07
DK157021B (da) 1989-10-30

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee