AT364451B - Verfahren zur herstellung von lokalanaesthetisch wirksamen kombinationspraeparaten - Google Patents

Verfahren zur herstellung von lokalanaesthetisch wirksamen kombinationspraeparaten

Info

Publication number
AT364451B
AT364451B AT0859578A AT859578A AT364451B AT 364451 B AT364451 B AT 364451B AT 0859578 A AT0859578 A AT 0859578A AT 859578 A AT859578 A AT 859578A AT 364451 B AT364451 B AT 364451B
Authority
AT
Austria
Prior art keywords
localanethetically
producing
effective combination
combination preparations
preparations
Prior art date
Application number
AT0859578A
Other languages
English (en)
Other versions
ATA859578A (de
Inventor
Berndt Fredrik Julius Broberg
Hans Christer Arvid Evers
Original Assignee
Astra Laekemedel Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Laekemedel Ab filed Critical Astra Laekemedel Ab
Publication of ATA859578A publication Critical patent/ATA859578A/de
Application granted granted Critical
Publication of AT364451B publication Critical patent/AT364451B/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245Amino benzoic acid types, e.g. procaine, novocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
AT0859578A 1977-12-01 1978-12-01 Verfahren zur herstellung von lokalanaesthetisch wirksamen kombinationspraeparaten AT364451B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE7713618A SE7713618L (sv) 1977-12-01 1977-12-01 Lokalanestetisk blandning

Publications (2)

Publication Number Publication Date
ATA859578A ATA859578A (de) 1981-03-15
AT364451B true AT364451B (de) 1981-10-27

Family

ID=20333074

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0859578A AT364451B (de) 1977-12-01 1978-12-01 Verfahren zur herstellung von lokalanaesthetisch wirksamen kombinationspraeparaten

Country Status (19)

Country Link
US (2) US4529601A (de)
EP (1) EP0002425B1 (de)
JP (1) JPS54101414A (de)
AR (1) AR218948A1 (de)
AT (1) AT364451B (de)
AU (1) AU525417B2 (de)
CA (1) CA1118350A (de)
DE (1) DE2861326D1 (de)
DK (1) DK154187C (de)
FI (1) FI68173C (de)
HK (1) HK43284A (de)
IE (1) IE47682B1 (de)
LU (1) LU88309I2 (de)
MY (1) MY8500061A (de)
NL (1) NL930051I2 (de)
NO (1) NO149913C (de)
NZ (1) NZ189026A (de)
SE (1) SE7713618L (de)
SG (1) SG8484G (de)

Families Citing this family (143)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2163956B (en) * 1984-09-08 1988-03-30 Ile De France Percutaneous anaesthetic composition for topical application
DE3800637A1 (de) * 1987-09-01 1989-03-09 Tetzner Volkmar Arzneimittel
US5446070A (en) * 1991-02-27 1995-08-29 Nover Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
US5234957A (en) * 1991-02-27 1993-08-10 Noven Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
GB9101986D0 (en) * 1991-01-30 1991-03-13 Smith & Nephew Pharmaceutical compositions
US5332576A (en) * 1991-02-27 1994-07-26 Noven Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
GB9105977D0 (en) * 1991-03-21 1991-05-08 Smith & Nephew Percutaneous anaesthesia
IL101387A (en) * 1992-03-26 1999-11-30 Pharmos Ltd Emulsion with enhanced topical and/or transdermal systemic effect utilizing submicron oil droplets
US6113921A (en) * 1993-03-23 2000-09-05 Pharmos Corp. Topical and transdermal delivery system utilizing submicron oil spheres
US5585398A (en) * 1994-07-15 1996-12-17 Ernst; Amy A. Topical anesthetic comprising lidocaine, adrenaline, and tetracaine, and its method of use
US5635540A (en) * 1994-12-09 1997-06-03 The University Of Virginia Patent Foundation Stabilized topical pharmaceutical preparations
US6245347B1 (en) 1995-07-28 2001-06-12 Zars, Inc. Methods and apparatus for improved administration of pharmaceutically active compounds
US20040265353A1 (en) * 1995-07-28 2004-12-30 Zars, Inc. Systems and methods for treating panic attacks
US5658583A (en) * 1995-07-28 1997-08-19 Zhang; Jie Apparatus and methods for improved noninvasive dermal administration of pharmaceuticals
US6284266B1 (en) 1995-07-28 2001-09-04 Zars, Inc. Methods and apparatus for improved administration of fentanyl and sufentanil
US5776859A (en) * 1995-11-15 1998-07-07 Nickel; Alfred A. Sodium channel active novel compounds and related processes and bioassay techniques
US7799337B2 (en) 1997-07-21 2010-09-21 Levin Bruce H Method for directed intranasal administration of a composition
US6432986B2 (en) * 1997-07-21 2002-08-13 Bruce H. Levin Compositions, kits, and methods for inhibiting cerebral neurovascular disorders and muscular headaches
US5993836A (en) * 1998-04-28 1999-11-30 Castillo; James G. Topical anesthetic formulation
US6114344A (en) * 1998-07-16 2000-09-05 Aryx Therapeutics Long-acting local anesthetics
US6726673B1 (en) 1999-05-24 2004-04-27 Zars, Inc. Methods and apparatus for improved administration of testosterone pharmaceuticals
US6955819B2 (en) 1998-09-29 2005-10-18 Zars, Inc. Methods and apparatus for using controlled heat to regulate transdermal and controlled release delivery of fentanyl, other analgesics, and other medical substances
US6299902B1 (en) 1999-05-19 2001-10-09 The University Of Georgia Research Foundation, Inc. Enhanced transdermal anesthesia of local anesthetic agents
US6453648B1 (en) 1999-07-06 2002-09-24 Zars, Inc. Method for manufacturing a heat generating apparatus
US6329398B1 (en) * 1999-09-07 2001-12-11 Stephen M. Zappala Preemptive analgesic agent and methods of use
US6413499B1 (en) 2000-01-06 2002-07-02 Bryan M. Clay Methods and kits for maxillary dental anesthesia by means of a nasal deliverable anesthetic
US6261595B1 (en) 2000-02-29 2001-07-17 Zars, Inc. Transdermal drug patch with attached pocket for controlled heating device
US8512718B2 (en) 2000-07-03 2013-08-20 Foamix Ltd. Pharmaceutical composition for topical application
USRE44145E1 (en) 2000-07-07 2013-04-09 A.V. Topchiev Institute Of Petrochemical Synthesis Preparation of hydrophilic pressure sensitive adhesives having optimized adhesive properties
US8206738B2 (en) 2001-05-01 2012-06-26 Corium International, Inc. Hydrogel compositions with an erodible backing member
US20050113510A1 (en) 2001-05-01 2005-05-26 Feldstein Mikhail M. Method of preparing polymeric adhesive compositions utilizing the mechanism of interaction between the polymer components
US8840918B2 (en) * 2001-05-01 2014-09-23 A. V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences Hydrogel compositions for tooth whitening
EP1390085B1 (de) 2001-05-01 2009-08-05 A.V. Topchiev Institute of Petrochemical Synthesis Hydrogel-zusammensetzungen
US20050215727A1 (en) 2001-05-01 2005-09-29 Corium Water-absorbent adhesive compositions and associated methods of manufacture and use
US6803420B2 (en) 2001-05-01 2004-10-12 Corium International Two-phase, water-absorbent bioadhesive composition
US8541021B2 (en) 2001-05-01 2013-09-24 A.V. Topchiev Institute Of Petrochemical Synthesis Hydrogel compositions demonstrating phase separation on contact with aqueous media
WO2002089849A1 (en) * 2001-05-07 2002-11-14 Corium International Compositions and delivery systems for administration of a local anesthetic agent
ATE526973T1 (de) 2001-06-18 2011-10-15 Noven Pharma Verbesserte arzneimittelabgabe in transdermalen systemen
US7425292B2 (en) * 2001-10-12 2008-09-16 Monosol Rx, Llc Thin film with non-self-aggregating uniform heterogeneity and drug delivery systems made therefrom
US20060039958A1 (en) * 2003-05-28 2006-02-23 Monosolrx, Llc. Multi-layer films having uniform content
US7357891B2 (en) * 2001-10-12 2008-04-15 Monosol Rx, Llc Process for making an ingestible film
US20070154527A1 (en) * 2001-10-12 2007-07-05 Monosoirx, Llc Topical film compositions for delivery of actives
US8603514B2 (en) 2002-04-11 2013-12-10 Monosol Rx, Llc Uniform films for rapid dissolve dosage form incorporating taste-masking compositions
US20070281003A1 (en) 2001-10-12 2007-12-06 Fuisz Richard C Polymer-Based Films and Drug Delivery Systems Made Therefrom
US7666337B2 (en) * 2002-04-11 2010-02-23 Monosol Rx, Llc Polyethylene oxide-based films and drug delivery systems made therefrom
US7910641B2 (en) * 2001-10-12 2011-03-22 Monosol Rx, Llc PH modulated films for delivery of actives
US8765167B2 (en) * 2001-10-12 2014-07-01 Monosol Rx, Llc Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US20110033542A1 (en) * 2009-08-07 2011-02-10 Monosol Rx, Llc Sublingual and buccal film compositions
US8900498B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for manufacturing a resulting multi-layer pharmaceutical film
US8900497B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for making a film having a substantially uniform distribution of components
US11207805B2 (en) 2001-10-12 2021-12-28 Aquestive Therapeutics, Inc. Process for manufacturing a resulting pharmaceutical film
US8663687B2 (en) 2001-10-12 2014-03-04 Monosol Rx, Llc Film compositions for delivery of actives
US10285910B2 (en) 2001-10-12 2019-05-14 Aquestive Therapeutics, Inc. Sublingual and buccal film compositions
US20190328679A1 (en) 2001-10-12 2019-10-31 Aquestive Therapeutics, Inc. Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US20100021526A1 (en) * 2001-10-12 2010-01-28 Monosol Rx, Llc Ph modulated films for delivery of actives
US8017150B2 (en) 2002-04-11 2011-09-13 Monosol Rx, Llc Polyethylene oxide-based films and drug delivery systems made therefrom
AU2003268015A1 (en) * 2002-07-22 2004-02-09 Kosmos Pharma Packaging and dispensing of rapid dissolve dosage form
US20040076671A1 (en) * 2002-10-21 2004-04-22 Aletha Tippett Methods and compositions for topical wound treatment
IL152486A0 (en) 2002-10-25 2003-05-29 Meir Eini Alcohol-free cosmetic and pharmaceutical foam carrier
US8486376B2 (en) 2002-10-25 2013-07-16 Foamix Ltd. Moisturizing foam containing lanolin
US9265725B2 (en) 2002-10-25 2016-02-23 Foamix Pharmaceuticals Ltd. Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
AU2003279493B2 (en) 2002-10-25 2009-08-20 Foamix Pharmaceuticals Ltd. Cosmetic and pharmaceutical foam
US8119150B2 (en) * 2002-10-25 2012-02-21 Foamix Ltd. Non-flammable insecticide composition and uses thereof
US8119109B2 (en) 2002-10-25 2012-02-21 Foamix Ltd. Foamable compositions, kits and methods for hyperhidrosis
US7700076B2 (en) 2002-10-25 2010-04-20 Foamix, Ltd. Penetrating pharmaceutical foam
US7820145B2 (en) 2003-08-04 2010-10-26 Foamix Ltd. Oleaginous pharmaceutical and cosmetic foam
US9668972B2 (en) 2002-10-25 2017-06-06 Foamix Pharmaceuticals Ltd. Nonsteroidal immunomodulating kit and composition and uses thereof
US20080138296A1 (en) 2002-10-25 2008-06-12 Foamix Ltd. Foam prepared from nanoemulsions and uses
US8900554B2 (en) 2002-10-25 2014-12-02 Foamix Pharmaceuticals Ltd. Foamable composition and uses thereof
US10117812B2 (en) * 2002-10-25 2018-11-06 Foamix Pharmaceuticals Ltd. Foamable composition combining a polar solvent and a hydrophobic carrier
US9211259B2 (en) 2002-11-29 2015-12-15 Foamix Pharmaceuticals Ltd. Antibiotic kit and composition and uses thereof
US7704518B2 (en) 2003-08-04 2010-04-27 Foamix, Ltd. Foamable vehicle and pharmaceutical compositions thereof
US7575739B2 (en) 2003-04-28 2009-08-18 Foamix Ltd. Foamable iodine composition
BR0301968A (pt) * 2003-05-22 2005-06-28 Cristalia Prod Quimicos Farm Misturas eutéticas ternárias e quaternárias constituìdas por substâncias anestésicas locais, seu emprego no preparo de composições farmacêuticas e seu uso em anestesia e analgesia tópica
ES2223277B1 (es) * 2003-06-19 2006-03-01 Fernando Bouffard Fita Composicion anestesica para administracion topica.
US20050014823A1 (en) * 2003-07-17 2005-01-20 Soderlund Patrick L. Topical anesthetic composition and method of administration
US8486374B2 (en) 2003-08-04 2013-07-16 Foamix Ltd. Hydrophilic, non-aqueous pharmaceutical carriers and compositions and uses
US8795693B2 (en) 2003-08-04 2014-08-05 Foamix Ltd. Compositions with modulating agents
AU2005210637B2 (en) 2004-01-30 2010-09-16 A.V. Topchiev Institute Of Petrochemical Synthesis Rapidly dissolving film for delivery of an active agent
EP1763370B1 (de) 2004-06-02 2015-04-29 NeurogesX Inc. Formulierungen mit capsaicin, einem lokalanästhetikum und/oder einem antipruritischen mittel zur behandlung von schmerzen
CA2576158C (en) 2004-08-05 2020-10-27 Corium International, Inc. Adhesive composition
JP2008540508A (ja) 2005-05-09 2008-11-20 フォーミックス エルティーディー. 起泡性ビヒクル及びその医薬組成物
US8623334B1 (en) 2005-09-29 2014-01-07 Alan J. Wickenhauser Topical anesthetic
US8263047B2 (en) * 2005-09-29 2012-09-11 Wickenhauser Alan J Topical anesthetic for dental procedures
EP1986601A2 (de) * 2006-01-20 2008-11-05 MonoSol Rx LLC Mit folie gefütterter beutel und verfahren zur herstellung dieses beutels
US20070172515A1 (en) * 2006-01-20 2007-07-26 Monosolrx, Llc Film bandage for mucosal administration of actives
WO2008036299A2 (en) * 2006-09-20 2008-03-27 Monosol Rx Llc Edible water-soluble film containing a foam reducing flavoring agent
JP5356235B2 (ja) * 2006-09-29 2013-12-04 モノソル アールエックス リミテッド ライアビリティ カンパニー フィルム−埋設包装およびその製造方法
US20080260655A1 (en) 2006-11-14 2008-10-23 Dov Tamarkin Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses
US20080146672A1 (en) * 2006-12-08 2008-06-19 Denton Marcia Marye Topical Eutectic Anesthetic Composition for Oral or Dermal Tissue
BRPI0700832B8 (pt) * 2007-03-16 2021-05-25 Biolab Sanus Farmaceutica Ltda composição anestésica tópica compreendendo suspensão de nanocápsulas poliméricas de lidocaína e prilocaína
US8636982B2 (en) 2007-08-07 2014-01-28 Foamix Ltd. Wax foamable vehicle and pharmaceutical compositions thereof
WO2009069006A2 (en) 2007-11-30 2009-06-04 Foamix Ltd. Foam containing benzoyl peroxide
WO2009072007A2 (en) 2007-12-07 2009-06-11 Foamix Ltd. Carriers, formulations, methods for formulating unstable active agents for external application and uses thereof
WO2010041141A2 (en) 2008-10-07 2010-04-15 Foamix Ltd. Oil-based foamable carriers and formulations
WO2009090558A2 (en) 2008-01-14 2009-07-23 Foamix Ltd. Poloxamer foamable pharmaceutical compositions with active agents and/or therapeutic cells and uses
US8473062B2 (en) 2008-05-01 2013-06-25 Autonomic Technologies, Inc. Method and device for the treatment of headache
US20090304776A1 (en) * 2008-06-06 2009-12-10 Totada Shantha Transmucosal delivery of therapeutic agents and methods of use thereof
US7883487B2 (en) * 2008-06-16 2011-02-08 Shantha Totada R Transdermal local anesthetic patch with injection port
US8412336B2 (en) 2008-12-29 2013-04-02 Autonomic Technologies, Inc. Integrated delivery and visualization tool for a neuromodulation system
US9012477B2 (en) * 2009-01-06 2015-04-21 Nuvo Research Inc. Method of treating neuropathic pain
EP2387394B1 (de) 2009-01-14 2018-05-02 Corium International, Inc. Transdermale verabreichung von tamsulosin
US9320908B2 (en) 2009-01-15 2016-04-26 Autonomic Technologies, Inc. Approval per use implanted neurostimulator
US8494641B2 (en) 2009-04-22 2013-07-23 Autonomic Technologies, Inc. Implantable neurostimulator with integral hermetic electronic enclosure, circuit substrate, monolithic feed-through, lead assembly and anchoring mechanism
CA2757302A1 (en) * 2009-04-01 2010-10-07 Andrew Crockett Methods for treating myofascial, muscle, and/or back pain
US20120087872A1 (en) 2009-04-28 2012-04-12 Foamix Ltd. Foamable Vehicles and Pharmaceutical Compositions Comprising Aprotic Polar Solvents and Uses Thereof
AU2010246064A1 (en) * 2009-05-04 2011-12-22 Zars Pharma, Inc. Methods of treating pains associated with neuroma, nerve entrapment, and other conditions
US9186334B2 (en) 2009-05-04 2015-11-17 Nuvo Research Inc. Heat assisted lidocaine and tetracaine for transdermal analgesia
CA2769625C (en) 2009-07-29 2017-04-11 Foamix Ltd. Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses
WO2011013008A2 (en) 2009-07-29 2011-02-03 Foamix Ltd. Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses
WO2011014850A2 (en) 2009-07-31 2011-02-03 Nuvo Research Inc. Topical eutectic-based formulations
US8475832B2 (en) 2009-08-07 2013-07-02 Rb Pharmaceuticals Limited Sublingual and buccal film compositions
US9849142B2 (en) 2009-10-02 2017-12-26 Foamix Pharmaceuticals Ltd. Methods for accelerated return of skin integrity and for the treatment of impetigo
CN102686205A (zh) 2009-10-02 2012-09-19 弗艾米克斯有限公司 局部四环素组合物
EP2498819A2 (de) 2009-11-11 2012-09-19 Nuvo Research Inc. Topische etoricoxib-formulierung mit einer eutektischen mischung aus permeationsverstärkern
WO2011074015A2 (en) 2009-12-17 2011-06-23 Themis Medicare Limited Novel composition of pharmaceutical product to treat sexual dysfunction
CA2785643A1 (en) 2009-12-23 2011-06-30 Nuvo Research Inc. Highly permeating terbinafine formulation
AU2011205730C1 (en) 2010-01-14 2014-10-09 Nuvo Research Inc. Solid-forming local anesthetic formulations for pain control
ES2569339T3 (es) 2010-06-10 2016-05-10 Midatech Ltd. Sistemas de administración de película de nanopartículas
US9149959B2 (en) 2010-10-22 2015-10-06 Monosol Rx, Llc Manufacturing of small film strips
FR2977493B1 (fr) * 2011-07-05 2014-02-14 Galderma Res & Dev Nouvelle composition anesthesique stable pour la reduction des reactions cutanees
FR2983731B1 (fr) * 2011-12-07 2014-04-25 Univ Paris Descartes Emulsions topiques a base de melanges eutectiques d'anesthesiques locaux et d'acide gras
US11213500B2 (en) 2011-12-27 2022-01-04 Cmpd Licensing, Llc Composition and method for compounded therapy
US11213501B2 (en) 2011-12-27 2022-01-04 Cmpd Licensing, Llc Composition and method for compounded therapy
US10813897B2 (en) 2011-12-27 2020-10-27 Cmpd Licensing, Llc Composition and method for compounded therapy
US9962391B2 (en) 2011-12-27 2018-05-08 Cmpd Licensing, Llc Composition and method for compounded therapy
US9468599B2 (en) 2011-12-27 2016-10-18 Cmpd Licensing, Llc Composition and method for compounded therapy
US9687444B2 (en) * 2012-01-02 2017-06-27 Andrew L. SKIGEN Veterinary active agent application
US9693969B2 (en) * 2012-01-02 2017-07-04 Andrew L. SKIGEN Mucous membrane active agent application
US9192572B2 (en) * 2012-01-02 2015-11-24 Andrew L. SKIGEN Oral anesthesia application
WO2015021387A2 (en) * 2013-08-09 2015-02-12 Britt George N Formulations for control and prevention of periodontal and perimplant diseases and other diseases and conditions of the mouth, and supra and sub-gingival delivery methods and systems for such formulations
JP6833811B2 (ja) 2015-08-03 2021-02-24 プレジデント アンド フェローズ オブ ハーバード カレッジ 荷電イオンチャネル遮断薬及び使用方法
EP3332776A4 (de) 2015-08-07 2019-03-20 Kaneka Corporation Pflaster
US10039830B2 (en) 2016-03-04 2018-08-07 Cetylite Industries, Inc. Topical anesthetic composition
US10231924B2 (en) 2016-03-23 2019-03-19 Cmpd Licensing, Llc Compounded topical composition and method
JP2019519487A (ja) 2016-05-05 2019-07-11 アクエスティブ セラピューティクス インコーポレイテッド 送達増強エピネフリン組成物
US11273131B2 (en) 2016-05-05 2022-03-15 Aquestive Therapeutics, Inc. Pharmaceutical compositions with enhanced permeation
MX2017011630A (es) 2016-09-08 2018-09-25 Foamix Pharmaceuticals Ltd Composiciones y metodos para tratar rosacea y acne.
WO2018071329A1 (en) 2016-10-13 2018-04-19 Trilogic Pharma Llc Topical formulations and treatments
US20210000744A1 (en) 2018-03-27 2021-01-07 The Regents Of The University Of California Drug delivery formulations
WO2020182535A1 (en) 2019-03-08 2020-09-17 Bayer Oy Uterine sound tube with anaesthetic applicator
CA3130054A1 (en) 2019-03-14 2020-09-17 Kaneka Corporation Patch
GB202302434D0 (en) 2023-02-21 2023-04-05 Univ Of Reading Compositions and method for the treatment of onychomycosis

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE141009C (de) *
GB190406112A (en) * 1904-03-12 1905-01-12 Robinson & Sons Ltd Improvements in Medical Plasters and the like.
GB121812A (en) * 1918-01-02 1919-01-02 William Harry Lomax Improvements in and connected with Means for Storing and Carrying Saccharine, Drugs, Medicaments or the like.
US2286718A (en) * 1935-12-17 1942-06-16 Curtis David Anesthetic compound and solvent for the same
US2175782A (en) * 1936-05-06 1939-10-10 Rorer Inc William H Anesthetic
US2142537A (en) * 1936-07-22 1939-01-03 Rare Chemicals Inc Anesthetic ointment
US2277038A (en) * 1937-10-30 1942-03-24 Curtis David Anesthetic preparation
US2241331A (en) * 1939-01-27 1941-05-06 Wm S Merrell Co Suppository
US2340776A (en) * 1940-07-25 1944-02-01 Gallowhur And Company Inc Topical epithelial anesthetic
US2352691A (en) * 1941-07-25 1944-07-04 Curtis David Anesthetic compound and preparation
US2382546A (en) * 1941-11-03 1945-08-14 Curtis David Anesthetic solutions
US2395538A (en) * 1942-05-19 1946-02-26 Curtis David Anesthetic salts of p-aminobenzoic acid esters
US2457188A (en) * 1945-05-24 1948-12-28 Americaine Inc Benzocaine solution
GB697145A (en) * 1951-10-22 1953-09-16 Johannes Lohmann Improved method of impregnating or coating bandage material with medicamental media
US2933431A (en) * 1957-03-28 1960-04-19 Theodore H J Sperouleas Medicated tissue
GB889225A (de) * 1959-07-01
GB1083896A (en) * 1964-04-30 1967-09-20 Dunster Lab Ltd Vehicles for administering drugs
SE352239B (de) * 1966-11-30 1972-12-27 Astra Pharma Prod
DE1767657A1 (de) * 1968-05-31 1971-11-25 Gerhard Weinz Blaettchen zum Auflegen
US3619280A (en) * 1969-07-18 1971-11-09 Dustikin Products Inc Treated paper and nonwoven material for wiping surfaces and method therefor
US3624224A (en) * 1969-12-22 1971-11-30 Schering Corp Novel first aid products
DE2057174A1 (de) * 1970-11-20 1972-05-25 Espe Pharm Praep Pharmazeutisches Produkt,insbesondere injizierbares Lokalanaesthetikum
US3751562A (en) * 1972-09-22 1973-08-07 Princeton Biomedix Medicated gelled oils
US4029794A (en) * 1973-06-12 1977-06-14 Astra Pharmaceutical Products, Inc. Pharmaceutical local anesthetic composition
AU513753B2 (en) * 1974-07-08 1980-12-18 Johnson & Johnson Antimicrobial composition
US4046886A (en) * 1975-01-17 1977-09-06 The Procter & Gamble Company Dermatological compositions

Also Published As

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AR218948A1 (es) 1980-07-15
DK154187C (da) 1989-03-13
LU88309I2 (fr) 1994-05-04
DK538978A (da) 1979-06-02
HK43284A (en) 1984-05-25
NL930051I2 (nl) 1994-01-17
MY8500061A (en) 1985-12-31
SE7713618L (sv) 1979-06-02
NO149913C (no) 1984-07-18
IE782350L (en) 1979-06-01
CA1118350A (en) 1982-02-16
ATA859578A (de) 1981-03-15
DE2861326D1 (en) 1982-01-14
NO149913B (no) 1984-04-09
AU4196078A (en) 1979-06-07
DK154187B (da) 1988-10-24
NL930051I1 (nl) 1993-09-01
JPS625133B2 (de) 1987-02-03
EP0002425B1 (de) 1981-11-11
SG8484G (en) 1985-02-08
JPS54101414A (en) 1979-08-10
US4529601A (en) 1985-07-16
FI68173B (fi) 1985-04-30
EP0002425A1 (de) 1979-06-13
AU525417B2 (en) 1982-11-04
US4562060A (en) 1985-12-31
IE47682B1 (en) 1984-05-30
NO783950L (no) 1979-06-05
FI783668A (fi) 1979-06-02
NZ189026A (en) 1984-07-06
FI68173C (fi) 1985-08-12

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