BR0301968A - Misturas eutéticas ternárias e quaternárias constituìdas por substâncias anestésicas locais, seu emprego no preparo de composições farmacêuticas e seu uso em anestesia e analgesia tópica - Google Patents

Misturas eutéticas ternárias e quaternárias constituìdas por substâncias anestésicas locais, seu emprego no preparo de composições farmacêuticas e seu uso em anestesia e analgesia tópica

Info

Publication number
BR0301968A
BR0301968A BR0301968-3A BR0301968A BR0301968A BR 0301968 A BR0301968 A BR 0301968A BR 0301968 A BR0301968 A BR 0301968A BR 0301968 A BR0301968 A BR 0301968A
Authority
BR
Brazil
Prior art keywords
preparation
pharmaceutical compositions
eutectic mixtures
ternary
local anesthetic
Prior art date
Application number
BR0301968-3A
Other languages
English (en)
Inventor
Ogari De Castro Pacheco
Elisa Mannochio De Souza Russo
Valter Freire Torres Russo
Original Assignee
Cristalia Prod Quimicos Farm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cristalia Prod Quimicos Farm filed Critical Cristalia Prod Quimicos Farm
Priority to BR0301968-3A priority Critical patent/BR0301968A/pt
Priority to EP04734190A priority patent/EP1633323B1/en
Priority to ES04734190T priority patent/ES2328814T3/es
Priority to PT04734190T priority patent/PT1633323E/pt
Priority to PCT/BR2004/000073 priority patent/WO2004103260A2/en
Priority to DE602004021595T priority patent/DE602004021595D1/de
Priority to US10/557,737 priority patent/US7763653B2/en
Priority to AT04734190T priority patent/ATE433743T1/de
Publication of BR0301968A publication Critical patent/BR0301968A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Anesthesiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

"MISTURAS EUTéTICAS TERNáRIAS E QUATERNáRIAS CONSTITUìDAS POR SUBSTâNCIAS ANESTéSICAS LOCAIS, SEU EMPREGO NO PREPARO DE COMPOSIçõES FARMACêUTICAS E SEU USO EM ANESTESIA E ANALGESIA TóPICA". A presente invenção descreve misturas eutéticas ternárias e quaternárias estáveis compostas por substâncias anestésicas locais ativas. Estas misturas eutéticas apresentam a propriedade de possuírem ponto de fusão inferior a 20<198>C e consistem de líquidos homogêneos úteis no preparo de composições farmacêuticas empregadas para proporcionar a anestesia ou analgesia tópica de tecidos como a pele e mucosas.
BR0301968-3A 2003-05-22 2003-05-22 Misturas eutéticas ternárias e quaternárias constituìdas por substâncias anestésicas locais, seu emprego no preparo de composições farmacêuticas e seu uso em anestesia e analgesia tópica BR0301968A (pt)

Priority Applications (8)

Application Number Priority Date Filing Date Title
BR0301968-3A BR0301968A (pt) 2003-05-22 2003-05-22 Misturas eutéticas ternárias e quaternárias constituìdas por substâncias anestésicas locais, seu emprego no preparo de composições farmacêuticas e seu uso em anestesia e analgesia tópica
EP04734190A EP1633323B1 (en) 2003-05-22 2004-05-21 Ternary eutectic mixtures of local anesthetics
ES04734190T ES2328814T3 (es) 2003-05-22 2004-05-21 Mezclas eutecticas ternarias de anestesicos locales.
PT04734190T PT1633323E (pt) 2003-05-22 2004-05-21 Misturas eutéticas ternárias e quaternárias
PCT/BR2004/000073 WO2004103260A2 (en) 2003-05-22 2004-05-21 Ternary and quaternary eutectic mixtures.
DE602004021595T DE602004021595D1 (de) 2003-05-22 2004-05-21 Ternäre eutektische gemische von lokalanaesthetika
US10/557,737 US7763653B2 (en) 2003-05-22 2004-05-21 Ternary and quaternary eutectic mixtures of local anesthetics substances
AT04734190T ATE433743T1 (de) 2003-05-22 2004-05-21 Ternäre eutektische gemische von lokalanaesthetika

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BR0301968-3A BR0301968A (pt) 2003-05-22 2003-05-22 Misturas eutéticas ternárias e quaternárias constituìdas por substâncias anestésicas locais, seu emprego no preparo de composições farmacêuticas e seu uso em anestesia e analgesia tópica

Publications (1)

Publication Number Publication Date
BR0301968A true BR0301968A (pt) 2005-06-28

Family

ID=33459589

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0301968-3A BR0301968A (pt) 2003-05-22 2003-05-22 Misturas eutéticas ternárias e quaternárias constituìdas por substâncias anestésicas locais, seu emprego no preparo de composições farmacêuticas e seu uso em anestesia e analgesia tópica

Country Status (8)

Country Link
US (1) US7763653B2 (pt)
EP (1) EP1633323B1 (pt)
AT (1) ATE433743T1 (pt)
BR (1) BR0301968A (pt)
DE (1) DE602004021595D1 (pt)
ES (1) ES2328814T3 (pt)
PT (1) PT1633323E (pt)
WO (1) WO2004103260A2 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2223277B1 (es) * 2003-06-19 2006-03-01 Fernando Bouffard Fita Composicion anestesica para administracion topica.
US20080146672A1 (en) * 2006-12-08 2008-06-19 Denton Marcia Marye Topical Eutectic Anesthetic Composition for Oral or Dermal Tissue
CA2738524C (en) 2008-10-02 2013-11-26 Mylan Inc. Method for making a multilayer adhesive laminate
US9731026B2 (en) 2014-11-25 2017-08-15 Massachusetts Institute Of Technology Neat liquid pharmaceutical formulations
US10039830B2 (en) 2016-03-04 2018-08-07 Cetylite Industries, Inc. Topical anesthetic composition

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7713618L (sv) * 1977-12-01 1979-06-02 Astra Laekemedel Ab Lokalanestetisk blandning
US5635540A (en) * 1994-12-09 1997-06-03 The University Of Virginia Patent Foundation Stabilized topical pharmaceutical preparations
SE9601421D0 (sv) * 1996-04-12 1996-04-12 Astra Ab New composition
US5993836A (en) * 1998-04-28 1999-11-30 Castillo; James G. Topical anesthetic formulation
US20020006435A1 (en) * 2000-01-27 2002-01-17 Samuels Paul J. Transdermal anesthetic and vasodilator composition and methods for topical administration

Also Published As

Publication number Publication date
EP1633323B1 (en) 2009-06-17
WO2004103260A2 (en) 2004-12-02
PT1633323E (pt) 2009-09-24
DE602004021595D1 (de) 2009-07-30
ATE433743T1 (de) 2009-07-15
US20060270736A1 (en) 2006-11-30
WO2004103260A3 (en) 2005-09-15
EP1633323A4 (en) 2006-08-16
ES2328814T3 (es) 2009-11-18
US7763653B2 (en) 2010-07-27
EP1633323A2 (en) 2006-03-15

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B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

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