AT363196B - Verfahren zur herstellung von androstan-17-on-derivaten - Google Patents
Verfahren zur herstellung von androstan-17-on-derivatenInfo
- Publication number
- AT363196B AT363196B AT0504677A AT504677A AT363196B AT 363196 B AT363196 B AT 363196B AT 0504677 A AT0504677 A AT 0504677A AT 504677 A AT504677 A AT 504677A AT 363196 B AT363196 B AT 363196B
- Authority
- AT
- Austria
- Prior art keywords
- androstan
- derivatives
- producing
- producing androstan
- Prior art date
Links
- YJDYCULVYZDESB-HKQXQEGQSA-N (5r,8r,9s,10s,13s,14s)-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-one Chemical class C1CCC[C@]2(C)[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CC[C@H]21 YJDYCULVYZDESB-HKQXQEGQSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P33/00—Preparation of steroids
- C12P33/005—Degradation of the lateral chains at position 17
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
- C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
- C07J1/0037—Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being a saturated hydrocarbon group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
- C07J1/004—Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
- C07J1/0048—Alkynyl derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/863—Mycobacterium
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Steroid Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19762632677 DE2632677A1 (de) | 1976-07-16 | 1976-07-16 | Verfahren zur herstellung von androstan-17-on-derivaten und deren verwendung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ATA504677A ATA504677A (de) | 1980-12-15 |
| AT363196B true AT363196B (de) | 1981-07-10 |
Family
ID=5983514
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT0504677A AT363196B (de) | 1976-07-16 | 1977-07-13 | Verfahren zur herstellung von androstan-17-on-derivaten |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4179336A (forum.php) |
| JP (1) | JPS5315493A (forum.php) |
| AT (1) | AT363196B (forum.php) |
| BE (1) | BE856860A (forum.php) |
| CH (3) | CH627190A5 (forum.php) |
| CS (1) | CS200517B2 (forum.php) |
| DD (4) | DD132439A5 (forum.php) |
| DE (1) | DE2632677A1 (forum.php) |
| DK (1) | DK142372C (forum.php) |
| FR (4) | FR2365588A1 (forum.php) |
| GB (1) | GB1585786A (forum.php) |
| HU (4) | HU182681B (forum.php) |
| IE (1) | IE45304B1 (forum.php) |
| IT (1) | IT1077339B (forum.php) |
| NL (1) | NL7706638A (forum.php) |
| SE (1) | SE440779B (forum.php) |
| SU (1) | SU980628A3 (forum.php) |
| YU (1) | YU164277A (forum.php) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS55148083A (en) * | 1979-05-04 | 1980-11-18 | Mitsubishi Chem Ind Ltd | Microorganism |
| JPS55150893A (en) * | 1979-05-11 | 1980-11-25 | Mitsubishi Chem Ind Ltd | Novel microorganism |
| JPS578794A (en) * | 1980-06-17 | 1982-01-18 | Mitsubishi Chem Ind Ltd | Preparation of androstane-type steroid |
| US4755463A (en) * | 1982-05-25 | 1988-07-05 | Wisconsin Alumni Research Foundation | Process for preparing steroids |
| US4444884A (en) * | 1982-05-25 | 1984-04-24 | Wisconsin Alumni Research Foundation | Process for preparing steroids |
| DE69621281T2 (de) * | 1995-02-28 | 2002-12-05 | Nippon Shokubai Co., Ltd. | Acryl-Säure-Derivate, Verfahren zur Herstellung von Acryl-Säure-Derivaten und Acryl-Säure-Polymere |
| PT2644206T (pt) * | 2003-05-23 | 2019-07-10 | Nektar Therapeutics | Derivados de peg contendo duas cadeias de peg |
| KR101293278B1 (ko) * | 2009-10-29 | 2013-08-09 | 주식회사 한독 | 신규 혈관누출 차단제 |
| WO2012116290A2 (en) | 2011-02-25 | 2012-08-30 | Washington University | Neuroactive 17(20)-z-vinylcyano-substituted steroids, prodrugs thereof, and methods of treatment using same |
| AU2012323888A1 (en) | 2011-10-14 | 2014-05-29 | Sage Therapeutics, Inc. | 3,3 disubstituted 19-nor pregnane compounds, compositions, and uses thereof |
| KR102400891B1 (ko) | 2012-12-18 | 2022-05-20 | 워싱톤 유니버시티 | 신경활성 19-알콕시-17-치환된 스테로이드, 그의 전구약물, 및 그를 사용한 치료 방법 |
| EP2956466A4 (en) * | 2013-02-15 | 2016-11-02 | Univ Washington | NEUROACTIVE ENANTIOMERS 15, 16 AND 17 SUBSTITUTED STEROIDS AS MODULATORS FOR GABA-A RECEPTORS |
| US9512170B2 (en) | 2013-03-01 | 2016-12-06 | Washington University | Neuroactive 13, 17-substituted steroids as modulators for GABA type-A receptors |
| US9365502B2 (en) | 2013-03-11 | 2016-06-14 | Washington University | Neuroactive substituted cyclopenta[b]phenanthrenes as modulators for GABA type-A receptors |
| US9562026B2 (en) | 2013-03-14 | 2017-02-07 | Washington University | Neuroactive substituted cyclopent[a]anthracenes as modulators for GABA type-A receptors |
| WO2014169831A1 (en) | 2013-04-17 | 2014-10-23 | Sage Therapeutics, Inc. | 19-nor c3,3-disubstituted c21-c-bound heteroaryl steroids and methods of use thereof |
| JP6239091B2 (ja) | 2013-04-17 | 2017-11-29 | セージ セラピューティクス， インコーポレイテッド | １９−ノル神経刺激性ステロイドおよびその使用方法 |
| SI3498725T1 (sl) | 2013-04-17 | 2021-11-30 | Sage Therapeutics, Inc. | 19-NOR C3,3-disubstituiran C21-N-pirazolilni steroid za uporabo v terapiji |
| WO2014169836A1 (en) | 2013-04-17 | 2014-10-23 | Sage Therapeutics, Inc. | 19-nor neuroactive steroids and methods of use thereof |
| CA2918735C (en) | 2013-07-19 | 2023-08-01 | Sage Therapeutics, Inc. | Neuroactive steroids, compositions, and uses thereof |
| EP3035940B1 (en) | 2013-08-23 | 2018-10-17 | Sage Therapeutics, Inc. | Neuroactive steroids, compositions, and uses thereof |
| WO2015195962A1 (en) | 2014-06-18 | 2015-12-23 | Sage Therapeutics, Inc. | Neuroactive steroids, compositions, and uses thereof |
| HRP20201216T1 (hr) | 2014-10-16 | 2020-12-11 | Sage Therapeutics, Inc. | PRIPRAVCI I POSTUPCI ZA LIJEČENJE POREMEĆAJA CNS-a |
| MX2021004492A (es) | 2014-10-16 | 2022-12-05 | Sage Therapeutics Inc | Composiciones para el tratamiento de trastornos del snc. |
| JP6893173B2 (ja) | 2014-11-27 | 2021-06-23 | セージ セラピューティクス， インコーポレイテッド | Ｃｎｓ障害を処置するための組成物および方法 |
| PL3250210T3 (pl) | 2015-01-26 | 2021-07-26 | Sage Therapeutics, Inc. | Kompozycje i sposoby leczenia zaburzeń OUN |
| JP6875996B2 (ja) | 2015-02-20 | 2021-05-26 | セージ セラピューティクス， インコーポレイテッド | 神経刺激性ステロイド、組成物、およびその使用 |
| CA3030420A1 (en) | 2016-07-11 | 2018-01-18 | Sage Therapeutics, Inc. | C7, c12, and c16 substituted neuroactive steroids and their methods of use |
| JP7049313B2 (ja) | 2016-07-11 | 2022-04-06 | セージ セラピューティクス， インコーポレイテッド | Ｃ１７、ｃ２０、およびｃ２１置換神経刺激性ステロイドおよびそれらの使用方法 |
| WO2020243488A1 (en) | 2019-05-31 | 2020-12-03 | Sage Therapeutics, Inc. | Neuroactive steroids and compositions thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3451892A (en) * | 1965-10-19 | 1969-06-24 | Schering Corp | Process for the preparation of steroidal compounds |
| NL6705450A (forum.php) * | 1965-10-22 | 1968-10-21 | ||
| US3684657A (en) * | 1970-05-11 | 1972-08-15 | Searle & Co | Selective microbiological degradation of steroidal 17-alkyls |
| US3759791A (en) * | 1970-12-10 | 1973-09-18 | Searle & Co | Selective microbiological preparation of androst-4-ene-3,17-dione |
| US3738983A (en) * | 1971-08-06 | 1973-06-12 | Searle & Co | Process for the preparation of 3-(3beta,17beta-dihydroxyandrost-5-en-17alpha-yl) propionic acid gamma-lactone |
| DE2534911C2 (de) * | 1975-08-01 | 1985-04-18 | Schering AG, 1000 Berlin und 4709 Bergkamen | Verfahren zur Herstellung von 5-Androsten-17-on-Derivaten |
-
1976
- 1976-07-16 DE DE19762632677 patent/DE2632677A1/de active Granted
-
1977
- 1977-06-16 NL NL7706638A patent/NL7706638A/xx not_active Application Discontinuation
- 1977-07-01 YU YU01642/77A patent/YU164277A/xx unknown
- 1977-07-06 US US05/813,391 patent/US4179336A/en not_active Expired - Lifetime
- 1977-07-12 CH CH861377A patent/CH627190A5/de not_active IP Right Cessation
- 1977-07-13 IE IE1456/77A patent/IE45304B1/en unknown
- 1977-07-13 AT AT0504677A patent/AT363196B/de not_active IP Right Cessation
- 1977-07-13 CS CS774682A patent/CS200517B2/cs unknown
- 1977-07-14 DD DD7700200065A patent/DD132439A5/xx not_active IP Right Cessation
- 1977-07-14 DD DD77206210A patent/DD137235A5/xx unknown
- 1977-07-14 DD DD77206205A patent/DD136141A5/xx unknown
- 1977-07-14 DD DD77206207A patent/DD136142A5/xx unknown
- 1977-07-14 SE SE7708192A patent/SE440779B/xx not_active IP Right Cessation
- 1977-07-15 HU HU8020A patent/HU182681B/hu unknown
- 1977-07-15 SU SU772502698A patent/SU980628A3/ru active
- 1977-07-15 DK DK323677A patent/DK142372C/da not_active IP Right Cessation
- 1977-07-15 JP JP8493277A patent/JPS5315493A/ja active Granted
- 1977-07-15 IT IT25807/77A patent/IT1077339B/it active
- 1977-07-15 HU HU8018A patent/HU182789B/hu unknown
- 1977-07-15 HU HU8019A patent/HU182790B/hu unknown
- 1977-07-15 GB GB29800/77A patent/GB1585786A/en not_active Expired
- 1977-07-15 BE BE179384A patent/BE856860A/xx not_active IP Right Cessation
- 1977-07-15 HU HU77SCHE614A patent/HU179344B/hu not_active IP Right Cessation
- 1977-07-18 FR FR7721932A patent/FR2365588A1/fr active Granted
-
1978
- 1978-03-07 FR FR7806457A patent/FR2372176A1/fr active Pending
- 1978-03-07 FR FR7806456A patent/FR2372174A1/fr active Pending
- 1978-03-07 FR FR7806455A patent/FR2372175A1/fr active Pending
-
1981
- 1981-06-23 CH CH415281A patent/CH629222A5/de not_active IP Right Cessation
- 1981-06-23 CH CH415381A patent/CH629503A5/de not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ELJ | Ceased due to non-payment of the annual fee |