AT346328B - Verfahren zur herstellung des neuen 3- (4- bromphenyl)-n-methyl-3- (3-pyridyl)- allylamins,seiner stereoisomeren und seiner pharmazeutisch akzeptablen salze - Google Patents

Verfahren zur herstellung des neuen 3- (4- bromphenyl)-n-methyl-3- (3-pyridyl)- allylamins,seiner stereoisomeren und seiner pharmazeutisch akzeptablen salze

Info

Publication number
AT346328B
AT346328B AT882275A AT882275A AT346328B AT 346328 B AT346328 B AT 346328B AT 882275 A AT882275 A AT 882275A AT 882275 A AT882275 A AT 882275A AT 346328 B AT346328 B AT 346328B
Authority
AT
Austria
Prior art keywords
bromphenyl
allylamine
stereoisomers
pyridyl
methyl
Prior art date
Application number
AT882275A
Other languages
German (de)
English (en)
Other versions
ATA882275A (de
Inventor
Per Arvid Emil Carlsson
Bernt Sigfrid Emanuel Carnmalm
Svante Bertil Ross
Carl Bengt Johan Ulff
Original Assignee
Astra Laekemedel Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Laekemedel Ab filed Critical Astra Laekemedel Ab
Publication of ATA882275A publication Critical patent/ATA882275A/de
Application granted granted Critical
Publication of AT346328B publication Critical patent/AT346328B/de

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/26Radicals substituted by halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46Oxygen atoms
    • C07D213/50Ketonic radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/55Acids; Esters
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/56Amides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/57Nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT882275A 1974-11-21 1975-11-20 Verfahren zur herstellung des neuen 3- (4- bromphenyl)-n-methyl-3- (3-pyridyl)- allylamins,seiner stereoisomeren und seiner pharmazeutisch akzeptablen salze AT346328B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE7414622A SE388854B (sv) 1974-11-21 1974-11-21 Forfarande for framstellning av fenylpyridylaminderivat

Publications (2)

Publication Number Publication Date
ATA882275A ATA882275A (de) 1978-03-15
AT346328B true AT346328B (de) 1978-11-10

Family

ID=20322772

Family Applications (1)

Application Number Title Priority Date Filing Date
AT882275A AT346328B (de) 1974-11-21 1975-11-20 Verfahren zur herstellung des neuen 3- (4- bromphenyl)-n-methyl-3- (3-pyridyl)- allylamins,seiner stereoisomeren und seiner pharmazeutisch akzeptablen salze

Country Status (26)

Country Link
JP (1) JPS5176278A (da)
AR (2) AR211921A1 (da)
AT (1) AT346328B (da)
AU (1) AU501915B2 (da)
BE (1) BE835802A (da)
CA (1) CA1056834A (da)
CH (4) CH614937A5 (da)
DD (1) DD122528A5 (da)
DE (1) DE2550005A1 (da)
DK (1) DK147179C (da)
ES (4) ES442758A1 (da)
FI (1) FI61484C (da)
FR (1) FR2291751A1 (da)
GB (1) GB1530804A (da)
HU (1) HU171206B (da)
IE (1) IE42615B1 (da)
IL (1) IL48409A (da)
LU (1) LU73844A1 (da)
NL (1) NL7513648A (da)
NO (1) NO149775C (da)
NZ (1) NZ179247A (da)
PL (2) PL103784B1 (da)
SE (1) SE388854B (da)
SU (1) SU686614A3 (da)
YU (1) YU39153B (da)
ZA (1) ZA756893B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE409860B (sv) * 1977-07-04 1979-09-10 Astra Laekemedel Ab En ny mellanprodukt for framstellning av terapeutiskt aktiva pyridinforeningar
DE2857020A1 (de) * 1977-07-04 1981-01-08 Astra Laekemedel Ab A novel intermediate for preparation of therapeutically active pyridine compounds
SE7909514L (sv) 1979-11-16 1981-05-17 Astra Laekemedel Ab Nya halofenyl-pyridyl-allylaminderivat
US4312368A (en) * 1980-02-20 1982-01-26 Philip Morris, Incorporated Smoking compositions
US5148817A (en) * 1980-11-07 1992-09-22 Philip Morris Incorporated Smoking compositions
CA1150269A (en) * 1980-11-14 1983-07-19 Carl B. J. Ulff Process for preparing 3-(4-bromophenyl)-3-(3-pyridyl)-allylamines

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH83A (fr) * 1888-11-17 1889-01-10 Fontainemelon Horlogerie Perfectionnements apportés à la construction des montres de tous calibres

Also Published As

Publication number Publication date
CH615665A5 (en) 1980-02-15
PL103784B1 (pl) 1979-07-31
NO149775B (no) 1984-03-12
AR210517A1 (es) 1977-08-15
ATA882275A (de) 1978-03-15
CH626065A5 (en) 1981-10-30
CH614937A5 (en) 1979-12-28
AU8662775A (en) 1977-05-19
IE42615B1 (en) 1980-09-10
ES452173A1 (es) 1977-10-01
GB1530804A (en) 1978-11-01
ES452171A1 (es) 1977-10-01
ES442758A1 (es) 1977-04-01
IL48409A0 (en) 1976-01-30
CA1056834A (en) 1979-06-19
HU171206B (hu) 1977-12-28
AU501915B2 (en) 1979-07-05
FI61484B (fi) 1982-04-30
YU293975A (en) 1982-08-31
DK147179C (da) 1984-11-19
PL103999B1 (pl) 1979-07-31
ES452172A1 (es) 1977-10-01
FI753260A (da) 1976-05-22
NO149775C (no) 1984-06-20
BE835802A (fr) 1976-05-21
SE388854B (sv) 1979-03-26
YU39153B (en) 1984-06-30
FI61484C (fi) 1982-08-10
SU686614A1 (en) 1979-09-15
DK147179B (da) 1984-05-07
JPS5176278A (en) 1976-07-01
NZ179247A (en) 1978-03-06
NL7513648A (nl) 1976-05-25
CH626066A5 (en) 1981-10-30
DD122528A5 (da) 1976-10-12
SU686614A3 (ru) 1979-09-15
NO753849L (da) 1976-05-24
IL48409A (en) 1979-10-31
ZA756893B (en) 1976-10-27
FR2291751A1 (fr) 1976-06-18
IE42615L (en) 1976-05-21
SE7414622L (sv) 1976-05-24
LU73844A1 (da) 1976-09-06
DK518175A (da) 1976-05-22
AR211921A1 (es) 1978-04-14
FR2291751B1 (da) 1979-09-21
DE2550005A1 (de) 1976-05-26

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