AR248132A1 - Un nuevo metodo para la preparacion de 9-amino-1, 2, 3, 4-tetrahidroacridina y para la preparacion de hidrocloruro de tacrina. - Google Patents

Un nuevo metodo para la preparacion de 9-amino-1, 2, 3, 4-tetrahidroacridina y para la preparacion de hidrocloruro de tacrina.

Info

Publication number
AR248132A1
AR248132A1 AR92321794A AR32179492A AR248132A1 AR 248132 A1 AR248132 A1 AR 248132A1 AR 92321794 A AR92321794 A AR 92321794A AR 32179492 A AR32179492 A AR 32179492A AR 248132 A1 AR248132 A1 AR 248132A1
Authority
AR
Argentina
Prior art keywords
tetrahydroacridine
amino
acid
preparation
ethos
Prior art date
Application number
AR92321794A
Other languages
English (en)
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Application granted granted Critical
Publication of AR248132A1 publication Critical patent/AR248132A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/08—Nitrogen atoms
    • C07D219/10—Nitrogen atoms attached in position 9

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

UN METODO PARA PREPARAR 9-AMINO-1, 2, 3, 4-TETRAHIDROACRIDINA, QUE COMPRENDE HACER REACCIONAR 2-AMINOBENZONITRILO Y CICLOHEXANONA EN PRESENCIA DE UN CATALIZADOR ACIDO EN UN DISOLVENTE COMO XILENOS, TOLUENO, ETERES AROMATICOS, TALES COMO ANISOL Y DIMETOXIBENCENO, Y COMPUESTOS AROMATICOS HALOGENADOS, TALES COMO CLOROBENCENO Y DICLOROBENCENO Y DONDE EL CATALIZADOR ACIDO ES ACIDO P-TOLUENSULFONICO MONOHIDRATO, ACIDO METANSULFONICO Y ACIDO SULFURICO.
AR92321794A 1991-02-19 1992-02-17 Un nuevo metodo para la preparacion de 9-amino-1, 2, 3, 4-tetrahidroacridina y para la preparacion de hidrocloruro de tacrina. AR248132A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/656,389 US5155226A (en) 1991-02-19 1991-02-19 Method for the preparation of 9-amino-1,2,3,4-tetrahydroacridine

Publications (1)

Publication Number Publication Date
AR248132A1 true AR248132A1 (es) 1995-06-30

Family

ID=24632830

Family Applications (1)

Application Number Title Priority Date Filing Date
AR92321794A AR248132A1 (es) 1991-02-19 1992-02-17 Un nuevo metodo para la preparacion de 9-amino-1, 2, 3, 4-tetrahidroacridina y para la preparacion de hidrocloruro de tacrina.

Country Status (24)

Country Link
US (1) US5155226A (es)
EP (1) EP0500006B1 (es)
JP (1) JP2782698B2 (es)
AR (1) AR248132A1 (es)
AT (1) ATE144980T1 (es)
AU (1) AU639656B2 (es)
BR (1) BR9200524A (es)
CA (1) CA2061422A1 (es)
CZ (1) CZ280649B6 (es)
DE (1) DE69214974T2 (es)
DK (1) DK0500006T3 (es)
ES (1) ES2095338T3 (es)
FI (1) FI97542C (es)
GR (1) GR3021687T3 (es)
HU (1) HU212942B (es)
IE (1) IE76739B1 (es)
IL (1) IL100970A (es)
MX (1) MX9200672A (es)
NO (1) NO178110C (es)
NZ (1) NZ241624A (es)
PH (1) PH29991A (es)
PL (1) PL166949B1 (es)
RU (1) RU2076099C1 (es)
ZA (1) ZA921160B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5053513A (en) * 1990-03-29 1991-10-01 Hoechst-Roussel Pharmaceuticals Incorporated Method of reducing a carbonyl containing acridine
DE59409129D1 (de) * 1993-11-26 2000-03-09 Karla Lehmann Verwendung von lithiumverbindungen zur behandlung und prophylaxe des morbus alzheimer
AU1282099A (en) * 1997-10-29 1999-05-17 Bonnie M. Davis Method for treatment of disorders of attention
EP1891954A3 (en) * 1998-09-30 2009-01-14 Takeda Pharmaceutical Company Limited Acetylcholinesterase inhibitors for improving excretory potency of urinary bladder
US20020177593A1 (en) * 1998-09-30 2002-11-28 Yuji Ishihara Agents and crystals for improving excretory potency of urinary bladder
CN105503840B (zh) * 2015-12-04 2019-02-01 广东工业大学 一种含三氮唑基的他克林-香豆素衍生物及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK569087A (da) * 1986-10-31 1988-05-01 Sumitomo Pharma Quinolin-derivater, deres fremstilling og anvendelse
IL87861A0 (en) * 1987-10-05 1989-03-31 Pfizer 4-aminopyridine derivatives
GB8827704D0 (en) * 1988-11-28 1988-12-29 Fujisawa Pharmaceutical Co New acridine derivatives & processes for their production
FR2640508B1 (fr) * 1988-12-19 1994-07-01 Dietlin Francois Nouvelles compositions et nouveaux produits pharmaceutiques assurant la regeneration de leucocytes et leur emploi pour le traitement du syndrome immuno-deficitaire

Also Published As

Publication number Publication date
CA2061422A1 (en) 1992-08-20
DE69214974D1 (de) 1996-12-12
NO178110B (no) 1995-10-16
HU212942B (en) 1996-12-30
IE76739B1 (en) 1997-11-05
US5155226A (en) 1992-10-13
CZ280649B6 (cs) 1996-03-13
IL100970A (en) 1996-03-31
DE69214974T2 (de) 1997-05-22
FI920675A (fi) 1992-08-20
AU639656B2 (en) 1993-07-29
CS47792A3 (en) 1992-09-16
IL100970A0 (en) 1992-11-15
ATE144980T1 (de) 1996-11-15
FI920675A0 (fi) 1992-02-17
ES2095338T3 (es) 1997-02-16
EP0500006A1 (en) 1992-08-26
HU9200515D0 (en) 1992-05-28
PH29991A (en) 1996-10-29
PL166949B1 (pl) 1995-07-31
JP2782698B2 (ja) 1998-08-06
PL293510A1 (en) 1992-10-19
AU1107392A (en) 1992-08-27
RU2076099C1 (ru) 1997-03-27
BR9200524A (pt) 1992-10-20
ZA921160B (en) 1992-10-28
NZ241624A (en) 1994-03-25
GR3021687T3 (en) 1997-02-28
HUT64032A (en) 1993-11-29
MX9200672A (es) 1992-08-01
DK0500006T3 (da) 1997-04-07
NO920636D0 (no) 1992-02-18
NO920636L (no) 1992-08-20
FI97542B (fi) 1996-09-30
FI97542C (fi) 1997-01-10
EP0500006B1 (en) 1996-11-06
IE920510A1 (en) 1992-08-26
JPH04346975A (ja) 1992-12-02
NO178110C (no) 1996-01-24

Similar Documents

Publication Publication Date Title
DE69930269D1 (de) Wasserlösslische prodrugs von gehinderten phenolen
PT93523A (pt) Processo para a preparacao de novos derivados 4-fluoro-benzoicos
MX9205208A (es) Compuestos derivados del acido 5-amino-4-hidroxihexanoico, procedimiento para su preparacion y compociciones farmaceuticas que los contienen
AU5817998A (en) Sulfuric acid alkylation reactor system with static mixers
DE3587304D1 (de) Herstellung von aromatischen carbonylverbindungen.
PT888261E (pt) Processo para a preparacao de nitrobifenileno
AR248132A1 (es) Un nuevo metodo para la preparacion de 9-amino-1, 2, 3, 4-tetrahidroacridina y para la preparacion de hidrocloruro de tacrina.
ES2086346T3 (es) Derivados de acido quinoloncarboxilico, procedimiento para su fabricacion asi como su uso como agentes antiviricos.
BR9709750A (pt) Processos para a preparação da tioxantona e derivados da mesma
GB2188929B (en) Process for the production of halogenated organic compounds
NO860373L (no) Fremgangsmaate ved fremstilling av 2-alkoxy-n-(1-azabicyclo(2,2,2)octan-3-yl)amino-benzamider.
NO167976C (no) Fremgangsmaate ved fremstilling av 5-aminosalicylsyre.
PT87986A (pt) Processo para a preparacao de derivados de tieno-imidazol substituido e de composicoes farmaceuticas que os contem, apropriadas como agentes inibidores da secrecao do acido do estomago, para a proteccao do estomago, assim como para o tratamento de inflamacoes intestinais
BR8706286A (pt) Processo para preparacao de composto,sistema catalitico e processo para producao de poliolefina
GB2188853B (en) Crosslinked organic resins containing si02 and sulphonic acid groups, a process for the preparation thereof, and the use thereof
GB1554362A (en) Manufacture of isocyanates from substituted ureas
BR8806029A (pt) Processo e sistema catalisador para a producao de metanol
NO163965C (no) Fremgangsmaate ved fremstilling av karbamidsyre-estere.
ES2054987T3 (es) Hidroxi-1,2,3,4-tetrahidroaminoacridinas, un procedimiento para su preparacion y su uso como medicamentos.
IT8421401A0 (it) Processo per la preparazione di uretani aromatici da composti nitroaromatici.
BR8704403A (pt) Processo para a preparacao de anilinofumarato,de acido quinolino-2,3-dicarboxilico e de oxalacetatos de dialquila
KR100190221B1 (en) Pollution-free process for producing aromatic nitro compound without using mineral acid
BR8801792A (pt) Processo para a preparacao de um acido piridina-2,3-dicarboxilico e composto
IT1213371B (it) Procedimento di decomposizione dicomposti aromatici polialogenati.
FI930980A (fi) Menetelmä fenolin valmistamiseksi bentseenistä suoralla hapetuksella