PT93523A - Processo para a preparacao de novos derivados 4-fluoro-benzoicos - Google Patents
Processo para a preparacao de novos derivados 4-fluoro-benzoicosInfo
- Publication number
- PT93523A PT93523A PT93523A PT9352390A PT93523A PT 93523 A PT93523 A PT 93523A PT 93523 A PT93523 A PT 93523A PT 9352390 A PT9352390 A PT 9352390A PT 93523 A PT93523 A PT 93523A
- Authority
- PT
- Portugal
- Prior art keywords
- formula
- image
- radical
- group
- fluoro
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
- C07D211/32—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8903653A FR2644786B1 (fr) | 1989-03-21 | 1989-03-21 | Nouveaux derives fluoro-4 benzoiques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (2)
Publication Number | Publication Date |
---|---|
PT93523A true PT93523A (pt) | 1990-11-07 |
PT93523B PT93523B (pt) | 1996-03-29 |
Family
ID=9379890
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT93523A PT93523B (pt) | 1989-03-21 | 1990-03-20 | Processo para a preparacao de novos derivados 4-fluoro-benzoicos |
Country Status (15)
Country | Link |
---|---|
US (1) | US5077288A (pt) |
EP (1) | EP0389352B1 (pt) |
JP (1) | JPH0314563A (pt) |
AT (1) | ATE104279T1 (pt) |
AU (1) | AU618877B2 (pt) |
CA (1) | CA2012628C (pt) |
DE (1) | DE69008012T2 (pt) |
DK (1) | DK0389352T3 (pt) |
ES (1) | ES2054284T3 (pt) |
FR (1) | FR2644786B1 (pt) |
IE (1) | IE64920B1 (pt) |
NZ (1) | NZ232853A (pt) |
OA (1) | OA09199A (pt) |
PT (1) | PT93523B (pt) |
ZA (1) | ZA902142B (pt) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5134240A (en) * | 1987-10-15 | 1992-07-28 | Hoffmann-Laroche, Inc. | Bicyclic peroxides |
FR2667317B1 (fr) * | 1990-10-02 | 1992-12-04 | Synthelabo | Derives de 2-aminopyrimidine-4-carboxamide, leur preparation et leur application en therapeutique. |
ZA919797B (en) * | 1990-12-13 | 1992-10-28 | Smithkline Beecham Corp | Bicyclo-5,6-dihydro-7h-pyrrolo-1,20-imidazol-7-ols and 7-ones |
EP0524846A1 (fr) * | 1991-06-27 | 1993-01-27 | Synthelabo | Dérivés de 2-(pipéridin-1-y1) éthanol, leur préparation et leur application en thérapeutique |
FR2678270B1 (fr) * | 1991-06-27 | 1995-01-13 | Synthelabo | Derives de 2-(piperidin-1-yl)ethanol, leur preparation et leur application en therapeutique. |
FR2681325B1 (fr) * | 1991-09-16 | 1993-12-17 | Fabre Medicament Pierre | Derives de l'aminomethyl-4 piperidine, leur preparation et leur application en therapeutique. |
GB2285977B (en) * | 1994-01-24 | 1998-05-27 | Du Pont Merck Pharma | Novel azetidine antipsychotic drugs |
FR2716680B1 (fr) * | 1994-02-25 | 1996-04-05 | Adir | Nouveaux dérivés de benzodioxane, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
FR2735129B1 (fr) * | 1995-06-07 | 1997-07-11 | Adir | Nouveaux derives de l'indole, de l'indazole et du benzisoxazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
JP3335362B2 (ja) * | 1995-09-15 | 2002-10-15 | サノフィ―サンテラボ | キノレイン−2(1h)−オン誘導体セロトニンアンタゴニスト |
FR2739100B1 (fr) * | 1995-09-21 | 1997-10-31 | Synthelabo | Derives de 4-(omega-(4-(4-fluorobenzoyl)piperidin-1-yl)- alkyl)quinolein-2(1h)-one, leur preparation et leur application en therapeutique |
FR2739099B1 (fr) * | 1995-09-21 | 1997-10-31 | Synthelabo | Derives de 3-(omega-(4-(4-fluorobenzoyl)piperidin-1-yl)- alkyl)-3,4-dihydroquinolein-2(1h)-one, leur preparation et leur application en therapeutique |
GB0326221D0 (en) * | 2003-11-10 | 2003-12-17 | Merck Sharp & Dohme | Therapeutic agents,compositions,preparations and uses |
EP1600447A1 (en) * | 2004-05-28 | 2005-11-30 | Neuropharma S.A.U. | Butyrylcholinesterase selective inhibitors |
AU2009233315B2 (en) * | 2008-03-31 | 2013-08-29 | Sun Pharmaceutical Industries Ltd. | An improved process for the preparation of morphinane analogues |
TW201041868A (en) * | 2009-03-20 | 2010-12-01 | Intervet Int Bv | Anthelmintic agents and their use |
CN105189478B (zh) | 2013-01-07 | 2019-10-22 | 南加州大学 | 脱氧尿苷三磷酸酶抑制剂 |
JP6513095B2 (ja) * | 2014-01-03 | 2019-05-15 | ユニバーシティ オブ サザン カリフォルニア | ヘテロ原子含有デオキシウリジントリホスファターゼ阻害剤 |
CN104529942B (zh) * | 2014-12-10 | 2018-05-15 | 天津孚音生物科技发展有限公司 | 一种伐诺司林的合成方法 |
JP6836589B2 (ja) | 2015-07-08 | 2021-03-03 | シーブイ6 セラピューティクス (エヌアイ) リミテッド | ヒダントインを含むデオキシウリジントリホスファターゼ阻害剤 |
WO2017006283A1 (en) | 2015-07-08 | 2017-01-12 | Cv6 Therapeutics (Ni) Limited | Deoxyuridine triphosphatase inhibitors containing cyclopropano linkage |
WO2017006270A1 (en) | 2015-07-08 | 2017-01-12 | University Of Southern California | Deoxyuridine triphosphatase inhibitors |
US10570100B2 (en) | 2015-07-08 | 2020-02-25 | University Of Southern California | Deoxyuridine triphosphatase inhibitors containing amino sulfonyl linkage |
US10829457B2 (en) | 2016-11-23 | 2020-11-10 | Cv6 Therapeutics (Ni) Limited | Nitrogen ring linked deoxyuridine triphosphatase inhibitors |
US11014924B2 (en) | 2016-11-23 | 2021-05-25 | Cv6 Therapeutics (Ni) Limited | Hydantoin containing deoxyuridine triphosphatase inhibitors |
WO2018098206A1 (en) | 2016-11-23 | 2018-05-31 | Cv6 Therapeutics (Ni) Limited | Hydantoin containing deoxyuridine triphosphatase inhibitors |
US11174271B2 (en) | 2016-11-23 | 2021-11-16 | Cv6 Therapeutics (Ni) Limited | 6-membered uracil isosteres |
WO2018098209A1 (en) | 2016-11-23 | 2018-05-31 | Cv6 Therapeutics (Ni) Limited | Amino sulfonyl compounds |
US11247984B2 (en) | 2017-01-05 | 2022-02-15 | Cv6 Therapeutics (Ni) Limited | Uracil containing compounds |
JP2020527133A (ja) | 2017-06-20 | 2020-09-03 | インブリア ファーマシューティカルズ, インコーポレイテッド | 心臓代謝の効率を高めるための組成物および方法 |
US11780811B2 (en) | 2020-06-30 | 2023-10-10 | Imbria Pharmaceuticals, Inc. | Methods of synthesizing 2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]ethyl pyridine-3-carboxylate |
US11530184B2 (en) | 2020-06-30 | 2022-12-20 | Imbria Pharmaceuticals, Inc. | Crystal forms of 2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]ethyl pyridine-3-carboxylate |
US11883396B2 (en) | 2021-05-03 | 2024-01-30 | Imbria Pharmaceuticals, Inc. | Methods of treating kidney conditions using modified forms of trimetazidine |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4335127A (en) * | 1979-01-08 | 1982-06-15 | Janssen Pharmaceutica, N.V. | Piperidinylalkyl quinazoline compounds, composition and method of use |
US4443451A (en) * | 1981-07-15 | 1984-04-17 | Janssen Pharmaceutica N.V. | Bicyclic pyrimidin-5-one derivatives |
JPS5818390A (ja) * | 1981-07-15 | 1983-02-02 | ジヤンセン・フア−マシユ−チカ・ナ−ムロ−ゼ・フエンノ−トシヤツプ | 二環式ピリミジン−5−オン誘導体、その製法および薬効成分としてのその用途 |
US4665075A (en) * | 1984-12-05 | 1987-05-12 | Janssen Pharmaceutica N.V. | Derivatives of hydroxy- or amino-substituted (piperidinylalkyl)quinazolines |
CA1246074A (en) * | 1984-12-05 | 1988-12-06 | Albertus H.M.T. Van Heertum | Derivatives of hydroxy- or amino-substituted (piperidinylalkyl)quinazolines |
DK623586A (da) * | 1985-12-27 | 1987-06-28 | Eisai Co Ltd | Piperidinderivater eller salte deraf og farmaceutiske kompositioner indeholdende forbindelserne |
FR2643373B1 (fr) * | 1989-01-10 | 1993-12-31 | Adir Cie | Nouveaux derives des bisarylalcenes, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
JPH02264773A (ja) * | 1989-04-04 | 1990-10-29 | Ikeda Mohandou:Kk | ベンゾイルピペリジン誘導体及びその塩 |
-
1989
- 1989-03-21 FR FR8903653A patent/FR2644786B1/fr not_active Expired - Fee Related
-
1990
- 1990-03-08 NZ NZ232853A patent/NZ232853A/xx unknown
- 1990-03-20 JP JP2071715A patent/JPH0314563A/ja active Granted
- 1990-03-20 EP EP90400743A patent/EP0389352B1/fr not_active Expired - Lifetime
- 1990-03-20 US US07/496,279 patent/US5077288A/en not_active Expired - Fee Related
- 1990-03-20 ZA ZA902142A patent/ZA902142B/xx unknown
- 1990-03-20 PT PT93523A patent/PT93523B/pt not_active IP Right Cessation
- 1990-03-20 IE IE99790A patent/IE64920B1/en not_active IP Right Cessation
- 1990-03-20 DE DE69008012T patent/DE69008012T2/de not_active Expired - Fee Related
- 1990-03-20 CA CA002012628A patent/CA2012628C/fr not_active Expired - Fee Related
- 1990-03-20 ES ES90400743T patent/ES2054284T3/es not_active Expired - Lifetime
- 1990-03-20 AU AU51478/90A patent/AU618877B2/en not_active Ceased
- 1990-03-20 AT AT90400743T patent/ATE104279T1/de active
- 1990-03-20 DK DK90400743.2T patent/DK0389352T3/da active
- 1990-03-21 OA OA59753A patent/OA09199A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
AU618877B2 (en) | 1992-01-09 |
EP0389352B1 (fr) | 1994-04-13 |
JPH0587506B2 (pt) | 1993-12-16 |
CA2012628A1 (fr) | 1990-09-21 |
FR2644786B1 (fr) | 1993-12-31 |
ES2054284T3 (es) | 1994-08-01 |
US5077288A (en) | 1991-12-31 |
DE69008012D1 (de) | 1994-05-19 |
IE64920B1 (en) | 1995-09-20 |
PT93523B (pt) | 1996-03-29 |
ZA902142B (en) | 1990-12-28 |
EP0389352A1 (fr) | 1990-09-26 |
ATE104279T1 (de) | 1994-04-15 |
AU5147890A (en) | 1990-09-27 |
OA09199A (fr) | 1992-06-30 |
JPH0314563A (ja) | 1991-01-23 |
NZ232853A (en) | 1991-11-26 |
FR2644786A1 (fr) | 1990-09-28 |
CA2012628C (fr) | 2000-08-29 |
IE900997L (en) | 1990-09-21 |
DK0389352T3 (da) | 1994-07-18 |
DE69008012T2 (de) | 1994-11-03 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PT93523A (pt) | Processo para a preparacao de novos derivados 4-fluoro-benzoicos | |
DE69627035D1 (de) | Derivate von aminosäuren, sie enthaltende pharmazeutische zusammensetzungen sowie deren herstellunsgverfahren | |
TW289020B (pt) | ||
ES2128307T3 (es) | Derivados de 1,4,7,10-tetraaza-ciclododecano monosustituidos en n, procedimiento para su preparacion y agentes farmaceuticos que los contienen. | |
ATE124405T1 (de) | 1,4,7,10-tetraazacyclododecan-butyltriole, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel. | |
ATE150462T1 (de) | Pyrazolopyridinverbindungen und verfahren zu ihrer herstellung | |
ATE152092T1 (de) | Salpetersäureester mit pharmazeutischer wirkung und verfahren zu deren herstellung | |
NO923235D0 (no) | Cykliske iminderivater, samt fremgangsmaate for fremstilling av slike | |
ATE132496T1 (de) | 3-desmethyl-mevalonsäurederivate, verfahren zu ihrer herstellung, pharmazeutische präparate auf basis dieser verbindungen, ihre verwendung sowie zwischenprodukte | |
WO2003013484A3 (en) | N-monoacylated derivatives of o-phenylenediamines, their six membered heterocyclic analogues and their use as pharmaceutical agents | |
ES2196331T3 (es) | Derivados macrociclicos de cadena de 13 elementos de las eritromicinas a y b. | |
DK0734383T3 (da) | Cykliske amidderivater som neurokinin-A-antagonister | |
DK0422485T3 (da) | Quinoloncarboxylsyrederivater, fremgangsmåder til deres fremstilling samt deres anvendelse som antivirale midler | |
PT83535B (pt) | Processo para a preparacao de composicoes farmaceuticas contendo derivados de aminoacidos | |
DE59006868D1 (de) | 2-Alkyl-4-arylmethylaminochinoline, ihre Verwendung und daraus hergestellte Arzneimittel. | |
PT99563A (pt) | Processo para a preparacao de aminas biologicamente activas | |
ATE87916T1 (de) | 3-desmethyl-4-fluor-mevalonsaeurederivate, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen, ihre verwendung und zwischenprodukte. | |
EP0331092A3 (en) | Alpha-amino-carboxylic-acid derivatives, their preparation and use | |
PT92671A (pt) | Processo para a preparacao de ariloxipropanolaminotetralinas farmaceuticamente activas | |
DE69112432D1 (de) | Derivate von methylpiperazinoazepin, verfahren zu ihrer herstellung und verwendung. | |
DE58902264D1 (de) | Beta-lactam-antibiotika, verfahren zu ihrer herstellung und ihre verwendung als und in arzneimitteln. | |
ATE107311T1 (de) | Modifizierte splenopentine, verfahren zu ihrer herstellung und ihre verwendung. | |
ATE145647T1 (de) | Gem-diphosphonsäure-nitrosocarbamoylderivate, verfahren zu deren herstellung und sie enthaltende pharmazeutische zubereitungen | |
DE69215085D1 (de) | Aminoacylderivate von gem-diphosphonsauren,verfahren zu deren herstellung und pharmazeutische zubereitungen,die sie enthalten | |
MX9803557A (es) | Derivados de aminoacidos, medicamentos que contienen tales compuestos y metodos para producir tales compuestos. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG3A | Patent granted, date of granting |
Effective date: 19951215 |
|
MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20020630 |