ATE104279T1 - 4-fluorbenzolderivate, herstellungsverfahren und diese enthaltende pharmazeutische zusammensetzungen. - Google Patents
4-fluorbenzolderivate, herstellungsverfahren und diese enthaltende pharmazeutische zusammensetzungen.Info
- Publication number
- ATE104279T1 ATE104279T1 AT90400743T AT90400743T ATE104279T1 AT E104279 T1 ATE104279 T1 AT E104279T1 AT 90400743 T AT90400743 T AT 90400743T AT 90400743 T AT90400743 T AT 90400743T AT E104279 T1 ATE104279 T1 AT E104279T1
- Authority
- AT
- Austria
- Prior art keywords
- formula
- image
- radical
- manufacture
- processes
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
- C07D211/32—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8903653A FR2644786B1 (fr) | 1989-03-21 | 1989-03-21 | Nouveaux derives fluoro-4 benzoiques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE104279T1 true ATE104279T1 (de) | 1994-04-15 |
Family
ID=9379890
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90400743T ATE104279T1 (de) | 1989-03-21 | 1990-03-20 | 4-fluorbenzolderivate, herstellungsverfahren und diese enthaltende pharmazeutische zusammensetzungen. |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5077288A (de) |
| EP (1) | EP0389352B1 (de) |
| JP (1) | JPH0314563A (de) |
| AT (1) | ATE104279T1 (de) |
| AU (1) | AU618877B2 (de) |
| CA (1) | CA2012628C (de) |
| DE (1) | DE69008012T2 (de) |
| DK (1) | DK0389352T3 (de) |
| ES (1) | ES2054284T3 (de) |
| FR (1) | FR2644786B1 (de) |
| IE (1) | IE64920B1 (de) |
| NZ (1) | NZ232853A (de) |
| OA (1) | OA09199A (de) |
| PT (1) | PT93523B (de) |
| ZA (1) | ZA902142B (de) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5134240A (en) * | 1987-10-15 | 1992-07-28 | Hoffmann-Laroche, Inc. | Bicyclic peroxides |
| FR2667317B1 (fr) * | 1990-10-02 | 1992-12-04 | Synthelabo | Derives de 2-aminopyrimidine-4-carboxamide, leur preparation et leur application en therapeutique. |
| EP0563286A4 (en) * | 1990-12-13 | 1995-01-11 | Smithkline Beecham Corp | Novel csaids |
| FR2678270B1 (fr) * | 1991-06-27 | 1995-01-13 | Synthelabo | Derives de 2-(piperidin-1-yl)ethanol, leur preparation et leur application en therapeutique. |
| EP0524846A1 (de) * | 1991-06-27 | 1993-01-27 | Synthelabo | 2-(Piperidin-1-yl)ethanolderivate, ihre Herstellung und ihre Anwendung in der Therapie |
| FR2681325B1 (fr) * | 1991-09-16 | 1993-12-17 | Fabre Medicament Pierre | Derives de l'aminomethyl-4 piperidine, leur preparation et leur application en therapeutique. |
| GB2285977B (en) * | 1994-01-24 | 1998-05-27 | Du Pont Merck Pharma | Novel azetidine antipsychotic drugs |
| FR2716680B1 (fr) * | 1994-02-25 | 1996-04-05 | Adir | Nouveaux dérivés de benzodioxane, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
| FR2735129B1 (fr) * | 1995-06-07 | 1997-07-11 | Adir | Nouveaux derives de l'indole, de l'indazole et du benzisoxazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2739100B1 (fr) * | 1995-09-21 | 1997-10-31 | Synthelabo | Derives de 4-(omega-(4-(4-fluorobenzoyl)piperidin-1-yl)- alkyl)quinolein-2(1h)-one, leur preparation et leur application en therapeutique |
| ATE187172T1 (de) * | 1995-09-15 | 1999-12-15 | Sanofi Synthelabo | Chinolin-2-on derivate als serotonin antagonisten |
| FR2739099B1 (fr) * | 1995-09-21 | 1997-10-31 | Synthelabo | Derives de 3-(omega-(4-(4-fluorobenzoyl)piperidin-1-yl)- alkyl)-3,4-dihydroquinolein-2(1h)-one, leur preparation et leur application en therapeutique |
| GB0326221D0 (en) * | 2003-11-10 | 2003-12-17 | Merck Sharp & Dohme | Therapeutic agents,compositions,preparations and uses |
| EP1600447A1 (de) * | 2004-05-28 | 2005-11-30 | Neuropharma S.A.U. | Selektive Butyrylcholinesterase Inhibitoren |
| JP2011516464A (ja) * | 2008-03-31 | 2011-05-26 | サン・ファーマシューティカル・インダストリーズ・リミテッド | モルフィナン類似体の改良された調製方法 |
| TW201041868A (en) * | 2009-03-20 | 2010-12-01 | Intervet Int Bv | Anthelmintic agents and their use |
| US9809571B2 (en) | 2013-01-07 | 2017-11-07 | University Of Southern California | Deoxyuridine triphosphatase inhibitors |
| WO2015103489A1 (en) * | 2014-01-03 | 2015-07-09 | University Of Southern California | Heteroatom containing deoxyuridine triphosphatase inhibitors |
| CN104529942B (zh) * | 2014-12-10 | 2018-05-15 | 天津孚音生物科技发展有限公司 | 一种伐诺司林的合成方法 |
| WO2017006283A1 (en) | 2015-07-08 | 2017-01-12 | Cv6 Therapeutics (Ni) Limited | Deoxyuridine triphosphatase inhibitors containing cyclopropano linkage |
| US10570100B2 (en) | 2015-07-08 | 2020-02-25 | University Of Southern California | Deoxyuridine triphosphatase inhibitors containing amino sulfonyl linkage |
| WO2017006270A1 (en) | 2015-07-08 | 2017-01-12 | University Of Southern California | Deoxyuridine triphosphatase inhibitors |
| EA037990B1 (ru) | 2015-07-08 | 2021-06-21 | Св6 Терапьютикс (Най) Лимитед | Ингибиторы дезоксиуридинтрифосфатазы, содержащие гидантоин |
| WO2018098208A1 (en) | 2016-11-23 | 2018-05-31 | Cv6 Therapeutics (Ni) Limited | Nitrogen ring linked deoxyuridine triphosphatase inhibitors |
| WO2018098209A1 (en) | 2016-11-23 | 2018-05-31 | Cv6 Therapeutics (Ni) Limited | Amino sulfonyl compounds |
| US11014924B2 (en) | 2016-11-23 | 2021-05-25 | Cv6 Therapeutics (Ni) Limited | Hydantoin containing deoxyuridine triphosphatase inhibitors |
| WO2018098206A1 (en) | 2016-11-23 | 2018-05-31 | Cv6 Therapeutics (Ni) Limited | Hydantoin containing deoxyuridine triphosphatase inhibitors |
| WO2018098204A1 (en) | 2016-11-23 | 2018-05-31 | Cv6 Therapeutics (Ni) Limited | 6-membered uracil isosteres |
| US11247984B2 (en) | 2017-01-05 | 2022-02-15 | Cv6 Therapeutics (Ni) Limited | Uracil containing compounds |
| CA3068254A1 (en) | 2017-06-20 | 2018-12-27 | Imbria Pharmaceuticals, Inc. | Compositions and methods for increasing efficiency of cardiac metabolism |
| US11530184B2 (en) | 2020-06-30 | 2022-12-20 | Imbria Pharmaceuticals, Inc. | Crystal forms of 2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]ethyl pyridine-3-carboxylate |
| US11780811B2 (en) | 2020-06-30 | 2023-10-10 | Imbria Pharmaceuticals, Inc. | Methods of synthesizing 2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]ethyl pyridine-3-carboxylate |
| US11883396B2 (en) | 2021-05-03 | 2024-01-30 | Imbria Pharmaceuticals, Inc. | Methods of treating kidney conditions using modified forms of trimetazidine |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4335127A (en) * | 1979-01-08 | 1982-06-15 | Janssen Pharmaceutica, N.V. | Piperidinylalkyl quinazoline compounds, composition and method of use |
| US4443451A (en) * | 1981-07-15 | 1984-04-17 | Janssen Pharmaceutica N.V. | Bicyclic pyrimidin-5-one derivatives |
| JPS5818390A (ja) * | 1981-07-15 | 1983-02-02 | ジヤンセン・フア−マシユ−チカ・ナ−ムロ−ゼ・フエンノ−トシヤツプ | 二環式ピリミジン−５−オン誘導体、その製法および薬効成分としてのその用途 |
| CA1246074A (en) * | 1984-12-05 | 1988-12-06 | Albertus H.M.T. Van Heertum | Derivatives of hydroxy- or amino-substituted (piperidinylalkyl)quinazolines |
| US4665075A (en) * | 1984-12-05 | 1987-05-12 | Janssen Pharmaceutica N.V. | Derivatives of hydroxy- or amino-substituted (piperidinylalkyl)quinazolines |
| DK623586A (da) * | 1985-12-27 | 1987-06-28 | Eisai Co Ltd | Piperidinderivater eller salte deraf og farmaceutiske kompositioner indeholdende forbindelserne |
| FR2643373B1 (fr) * | 1989-01-10 | 1993-12-31 | Adir Cie | Nouveaux derives des bisarylalcenes, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
| JPH02264773A (ja) * | 1989-04-04 | 1990-10-29 | Ikeda Mohandou:Kk | ベンゾイルピペリジン誘導体及びその塩 |
-
1989
- 1989-03-21 FR FR8903653A patent/FR2644786B1/fr not_active Expired - Fee Related
-
1990
- 1990-03-08 NZ NZ232853A patent/NZ232853A/xx unknown
- 1990-03-20 IE IE99790A patent/IE64920B1/en not_active IP Right Cessation
- 1990-03-20 CA CA002012628A patent/CA2012628C/fr not_active Expired - Fee Related
- 1990-03-20 EP EP90400743A patent/EP0389352B1/de not_active Expired - Lifetime
- 1990-03-20 DK DK90400743.2T patent/DK0389352T3/da active
- 1990-03-20 AU AU51478/90A patent/AU618877B2/en not_active Ceased
- 1990-03-20 US US07/496,279 patent/US5077288A/en not_active Expired - Fee Related
- 1990-03-20 AT AT90400743T patent/ATE104279T1/de active
- 1990-03-20 DE DE69008012T patent/DE69008012T2/de not_active Expired - Fee Related
- 1990-03-20 ZA ZA902142A patent/ZA902142B/xx unknown
- 1990-03-20 JP JP2071715A patent/JPH0314563A/ja active Granted
- 1990-03-20 ES ES90400743T patent/ES2054284T3/es not_active Expired - Lifetime
- 1990-03-20 PT PT93523A patent/PT93523B/pt not_active IP Right Cessation
- 1990-03-21 OA OA59753A patent/OA09199A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2054284T3 (es) | 1994-08-01 |
| JPH0587506B2 (de) | 1993-12-16 |
| CA2012628C (fr) | 2000-08-29 |
| IE900997L (en) | 1990-09-21 |
| US5077288A (en) | 1991-12-31 |
| DE69008012T2 (de) | 1994-11-03 |
| PT93523A (pt) | 1990-11-07 |
| AU618877B2 (en) | 1992-01-09 |
| EP0389352A1 (de) | 1990-09-26 |
| OA09199A (fr) | 1992-06-30 |
| CA2012628A1 (fr) | 1990-09-21 |
| DK0389352T3 (da) | 1994-07-18 |
| AU5147890A (en) | 1990-09-27 |
| ZA902142B (en) | 1990-12-28 |
| NZ232853A (en) | 1991-11-26 |
| PT93523B (pt) | 1996-03-29 |
| FR2644786B1 (fr) | 1993-12-31 |
| EP0389352B1 (de) | 1994-04-13 |
| FR2644786A1 (fr) | 1990-09-28 |
| DE69008012D1 (de) | 1994-05-19 |
| IE64920B1 (en) | 1995-09-20 |
| JPH0314563A (ja) | 1991-01-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE104279T1 (de) | 4-fluorbenzolderivate, herstellungsverfahren und diese enthaltende pharmazeutische zusammensetzungen. | |
| FI942074A (fi) | nor-sappijohdannaisia, menetelmä niiden valmistamiseksi ja näiden yhdisteiden käyttö lääkeaineina | |
| DK0539204T3 (da) | Antivirale 4-substituerede-deoxy-2,3-didehydroderivater af alfa-D-neuraminsyre | |
| FI942075A0 (fi) | Sappihappojohdannaisten tetratsolijohdannaisia, menetelmä niiden valmistamiseksi ja näiden yhdisteiden käyttö lääkeaineina | |
| DE59103595D1 (de) | Neue phospholipid-derivate von nucleosiden, deren herstellung sowie deren verwendung als antivirale arzneimittel. | |
| DE59209769D1 (de) | Cyclische Iminoderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung | |
| DE59108930D1 (de) | Cyclische Iminoderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung | |
| DE69627035T2 (de) | Derivate von aminosäuren, sie enthaltende pharmazeutische zusammensetzungen sowie deren herstellunsgverfahren | |
| ES2074846T3 (es) | Nuevas naftil-etil-ureas y naftil-etil-tioureas, su procedimiento de preparacion y las composiciones farmaceuticas que las contienen. | |
| DE59308940D1 (de) | Cyclische Iminoderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel | |
| DK515489D0 (da) | Dispergerbar laegemiddelformulering | |
| DE69216221D1 (de) | Verbindungen mit guanidin-struktur und diese enthaltende pharmazeutische zusammensetzungen | |
| DE59006868D1 (de) | 2-Alkyl-4-arylmethylaminochinoline, ihre Verwendung und daraus hergestellte Arzneimittel. | |
| ES2111871T3 (es) | Nuevos derivados de aminoacidos, su procedimiento de preparacion y composiciones farmaceuticas que los contienen. | |
| ATE17350T1 (de) | Salicylsaeurederivate, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen und ihre verwendung. | |
| DE68906572T2 (de) | Peptide mit inhibitorischer wirkung auf enzymatische systeme, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen. | |
| ES2091570T3 (es) | Nuevos derivados peptidicos antagonistas de la bradiquidina, su procedimiento de preparacion y composiciones farmaceuticas que los contienen. | |
| ATE153032T1 (de) | Zyklische angiopeptin derivate, deren herstellung und pharmazeutische zusammensetzungen | |
| NO922635D0 (no) | Ny anvendelse av benzimidazolin-2-okso-1-karboksylsyrederivater | |
| ATE80629T1 (de) | Beta-lactam-antibiotika, verfahren zu ihrer herstellung und ihre verwendung als und in arzneimitteln. | |
| DE68909451D1 (de) | Peptide mit inhibitorischer wirkung auf enzymatische systeme, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen. | |
| ATE145647T1 (de) | Gem-diphosphonsäure-nitrosocarbamoylderivate, verfahren zu deren herstellung und sie enthaltende pharmazeutische zubereitungen |