AR246739A1 - Procedimiento para preparar derivados de tienoimidazol sustituidos. - Google Patents
Procedimiento para preparar derivados de tienoimidazol sustituidos.Info
- Publication number
- AR246739A1 AR246739A1 AR87306770A AR30677087A AR246739A1 AR 246739 A1 AR246739 A1 AR 246739A1 AR 87306770 A AR87306770 A AR 87306770A AR 30677087 A AR30677087 A AR 30677087A AR 246739 A1 AR246739 A1 AR 246739A1
- Authority
- AR
- Argentina
- Prior art keywords
- group
- alquil
- hydrogen
- formula
- alkyl
- Prior art date
Links
- JCZAVVUIFWZMQI-UHFFFAOYSA-N 1h-thieno[2,3-d]imidazole Chemical class N1C=NC2=C1C=CS2 JCZAVVUIFWZMQI-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 239000002731 stomach secretion inhibitor Substances 0.000 title 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical class [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 3
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- -1 CIAN Chemical class 0.000 abstract 1
- JCXJVPUVTGWSNB-UHFFFAOYSA-N Nitrogen dioxide Chemical class O=[N]=O JCXJVPUVTGWSNB-UHFFFAOYSA-N 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19863605395 DE3605395A1 (de) | 1986-02-20 | 1986-02-20 | Substituierte thienoimidazol-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische zubereitungen und ihre verwendung als magensaeuresekretionshemmer |
| DE19863623683 DE3623683A1 (de) | 1986-07-12 | 1986-07-12 | Substituierte thienoimidazol-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische zubereitungen und ihre verwendung als magensaeuresekretionshemmer |
| DE19873700436 DE3700436A1 (de) | 1987-01-09 | 1987-01-09 | Substituierte thienoimidazol-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische zubereitungen und ihre verwendung als magensaeuresekretionshemmer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR246739A1 true AR246739A1 (es) | 1994-09-30 |
Family
ID=27194035
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AR87306770A AR246739A1 (es) | 1986-02-20 | 1987-02-18 | Procedimiento para preparar derivados de tienoimidazol sustituidos. |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US4845118A (instruction) |
| EP (1) | EP0234485B1 (instruction) |
| JP (1) | JPH0633275B2 (instruction) |
| KR (2) | KR950001025B1 (instruction) |
| CN (1) | CN1021911C (instruction) |
| AR (1) | AR246739A1 (instruction) |
| AU (1) | AU590390B2 (instruction) |
| CA (1) | CA1337197C (instruction) |
| DE (1) | DE3777855D1 (instruction) |
| DK (1) | DK85087A (instruction) |
| EG (1) | EG18128A (instruction) |
| ES (1) | ES2032394T3 (instruction) |
| FI (1) | FI870672A7 (instruction) |
| GR (1) | GR3004765T3 (instruction) |
| HU (1) | HU197330B (instruction) |
| IE (1) | IE60572B1 (instruction) |
| IL (1) | IL81609A (instruction) |
| MA (1) | MA20880A1 (instruction) |
| NO (1) | NO170155C (instruction) |
| NZ (1) | NZ219320A (instruction) |
| PT (1) | PT84319B (instruction) |
| TN (1) | TNSN87024A1 (instruction) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI861772A7 (fi) * | 1985-05-07 | 1986-11-08 | Chemie Linz Ag | Uudet tieno(2,3)imidatsolijohdokset ja menetelmä niiden valmistamiseksi. |
| CA1256109A (en) * | 1986-09-10 | 1989-06-20 | Franz Rovenszky | Process for the preparation of derivatives of 4, 5-dihydrooxazoles |
| US4912101A (en) * | 1987-03-13 | 1990-03-27 | Fujirebio Kabushiki Kaisha | 4-aminomethyl-pyridyl-2-oxy derivatives having anti-ulcer activity |
| DE3723327A1 (de) * | 1987-07-15 | 1989-02-02 | Hoechst Ag | Substituierte thienoimidazol-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische zubereitungen und ihre verwendung als magensaeuresekretionshemmer, magenschutzmittel sowie als medikament gegen intestinale entzuendungen |
| AU622866B2 (en) * | 1987-07-21 | 1992-04-30 | Hoechst Aktiengesellschaft | Substituted thienoimidazole derivatives, processes for their preparation, pharmaceutical formulations containing them and their use as gastric acid secretion inhibitors |
| IT1222412B (it) * | 1987-07-31 | 1990-09-05 | Chiesi Farma Spa | Tiometil e sulfinil metil derivati ad azione antisecretiva acida gastrica,loro procedimento di preparazione e composizioni farmaceutiche che li contengono |
| FI89602C (fi) * | 1987-08-15 | 1993-10-25 | Hoechst Ag | Foerfarande foer framstaellning av terapeutiskt anvaendbara substituerade tienoimidazolderivat |
| DE3851133D1 (de) * | 1987-11-13 | 1994-09-22 | Hoechst Ag | Substituierte Thienoimidazol-Derivate, Verfahren zu ihrer Herstellung, sie enthaltende pharmazeutische Zubereitungen und ihre Verwendung als Magensäuresekretionshemmer. |
| FI885878L (fi) * | 1987-12-22 | 1989-06-23 | Hoechst Ag | Substituerade tienoimidazolderivat, foerfarande foer deras framstaellning, dessa innehaollande farmaceutiska kompositioner och deras anvaendning som inhibitorer vid avsoendring av magsyra. |
| US6852739B1 (en) | 1999-02-26 | 2005-02-08 | Nitromed Inc. | Methods using proton pump inhibitors and nitric oxide donors |
| SI1187601T1 (sl) | 1999-06-07 | 2005-12-31 | Altana Pharma Ag | Novi pripravek in dajalna oblika, ki obsega kislinsko labilen inhibitor protonske crpalke |
| US7186855B2 (en) | 2001-06-11 | 2007-03-06 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| US6818787B2 (en) | 2001-06-11 | 2004-11-16 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| US7232924B2 (en) | 2001-06-11 | 2007-06-19 | Xenoport, Inc. | Methods for synthesis of acyloxyalkyl derivatives of GABA analogs |
| US8048917B2 (en) | 2005-04-06 | 2011-11-01 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| EP1534278A4 (en) | 2002-08-01 | 2006-09-06 | Nitromed Inc | NITROSED PROTONATE PUMP INHIBITORS, COMPOSITIONS AND USE METHOD |
| WO2004112756A1 (en) | 2003-06-26 | 2004-12-29 | Isa Odidi | Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient |
| JP2007536349A (ja) * | 2004-05-07 | 2007-12-13 | ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング | 新規の医薬剤形及び製造方法 |
| US8394409B2 (en) | 2004-07-01 | 2013-03-12 | Intellipharmaceutics Corp. | Controlled extended drug release technology |
| US10624858B2 (en) | 2004-08-23 | 2020-04-21 | Intellipharmaceutics Corp | Controlled release composition using transition coating, and method of preparing same |
| US10064828B1 (en) | 2005-12-23 | 2018-09-04 | Intellipharmaceutics Corp. | Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems |
| EP2007360B1 (en) | 2006-04-03 | 2014-11-26 | Isa Odidi | Controlled release delivery device comprising an organosol coat |
| US10960077B2 (en) | 2006-05-12 | 2021-03-30 | Intellipharmaceutics Corp. | Abuse and alcohol resistant drug composition |
| EP2086543A2 (en) | 2006-10-27 | 2009-08-12 | The Curators of the University of Missouri | Compositions comprising at least one acid labile proton pump inhibiting agents, optionally other pharmaceutically active agents and methods of using same |
| US20080194307A1 (en) * | 2007-02-13 | 2008-08-14 | Jeff Sanger | Sports-based game of chance |
| US8247440B2 (en) | 2008-02-20 | 2012-08-21 | Curators Of The University Of Missouri | Composition comprising omeprazole, lansoprazole and at least one buffering agent |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3132167A1 (de) | 1981-08-14 | 1983-03-03 | Hoechst Ag, 6000 Frankfurt | "5(6)-phenylsulfonyloxy-benzimidazolderivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische zubereitungen und ihre verwendung gegen leberegel" |
| SE416649B (sv) | 1974-05-16 | 1981-01-26 | Haessle Ab | Forfarande for framstellning av foreningar som paverkar magsyrasekretionen |
| SE7804231L (sv) | 1978-04-14 | 1979-10-15 | Haessle Ab | Magsyrasekretionsmedel |
| US4472409A (en) | 1981-11-05 | 1984-09-18 | Byk Gulden Lomberg Chemische Fabrik Gesellschaft Mit Beschrankter Haftung | 2-Pyridylmethyl thio(sulfinyl)benzimidazoles with gastric acid secretion inhibiting effects |
| SE8300736D0 (sv) * | 1983-02-11 | 1983-02-11 | Haessle Ab | Novel pharmacologically active compounds |
| US4575554A (en) * | 1983-12-05 | 1986-03-11 | The Upjohn Company | Substituted 2-pyridylmethylthio- and sulfinyl-benzimidazoles as gastric antisecretory agents |
| GB8417171D0 (en) * | 1984-07-05 | 1984-08-08 | Beecham Group Plc | Compounds |
| AU568441B2 (en) | 1984-09-24 | 1987-12-24 | Upjohn Company, The | 2-(pyridylalkenesulfinyl) benzimidazole derivatives |
| FI861772A7 (fi) * | 1985-05-07 | 1986-11-08 | Chemie Linz Ag | Uudet tieno(2,3)imidatsolijohdokset ja menetelmä niiden valmistamiseksi. |
| WO1987005296A1 (en) * | 1986-03-07 | 1987-09-11 | Pfizer Inc. | 2-[(2-pyridyl)methylsulfinyl]thienoimidazoles and related compounds as antiulcer agents |
-
1987
- 1987-02-17 EP EP87102248A patent/EP0234485B1/de not_active Expired - Lifetime
- 1987-02-17 ES ES198787102248T patent/ES2032394T3/es not_active Expired - Lifetime
- 1987-02-17 DE DE8787102248T patent/DE3777855D1/de not_active Expired - Fee Related
- 1987-02-18 NZ NZ219320A patent/NZ219320A/xx unknown
- 1987-02-18 FI FI870672A patent/FI870672A7/fi not_active Application Discontinuation
- 1987-02-18 AR AR87306770A patent/AR246739A1/es active
- 1987-02-18 IL IL8160987A patent/IL81609A/en not_active IP Right Cessation
- 1987-02-18 EG EG88/87A patent/EG18128A/xx active
- 1987-02-19 CN CN87100719A patent/CN1021911C/zh not_active Expired - Fee Related
- 1987-02-19 DK DK085087A patent/DK85087A/da not_active Application Discontinuation
- 1987-02-19 JP JP62034687A patent/JPH0633275B2/ja not_active Expired - Lifetime
- 1987-02-19 NO NO870666A patent/NO170155C/no unknown
- 1987-02-19 CA CA000530139A patent/CA1337197C/en not_active Expired - Fee Related
- 1987-02-19 PT PT84319A patent/PT84319B/pt not_active IP Right Cessation
- 1987-02-19 AU AU69066/87A patent/AU590390B2/en not_active Ceased
- 1987-02-19 IE IE42187A patent/IE60572B1/en not_active IP Right Cessation
- 1987-02-20 TN TNTNSN87024A patent/TNSN87024A1/fr unknown
- 1987-02-20 MA MA21115A patent/MA20880A1/fr unknown
- 1987-02-20 KR KR1019870001431A patent/KR950001025B1/ko not_active Expired - Fee Related
- 1987-02-20 HU HU87669A patent/HU197330B/hu not_active IP Right Cessation
- 1987-12-22 US US07/136,360 patent/US4845118A/en not_active Expired - Fee Related
-
1988
- 1988-12-22 KR KR1019880017216A patent/KR890009937A/ko not_active Abandoned
-
1992
- 1992-05-29 GR GR920401113T patent/GR3004765T3/el unknown
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