EG18128A - Process for preparation of substituted thienoimidazole derivatives and their use as inhibitors of gastric acid secretion - Google Patents

Process for preparation of substituted thienoimidazole derivatives and their use as inhibitors of gastric acid secretion

Info

Publication number
EG18128A
EG18128A EG88/87A EG8887A EG18128A EG 18128 A EG18128 A EG 18128A EG 88/87 A EG88/87 A EG 88/87A EG 8887 A EG8887 A EG 8887A EG 18128 A EG18128 A EG 18128A
Authority
EG
Egypt
Prior art keywords
inhibitors
preparation
gastric acid
acid secretion
thienoimidazole derivatives
Prior art date
Application number
EG88/87A
Other languages
English (en)
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19863605395 external-priority patent/DE3605395A1/de
Priority claimed from DE19863623683 external-priority patent/DE3623683A1/de
Priority claimed from DE19873700436 external-priority patent/DE3700436A1/de
Application filed by Hoechst Ag filed Critical Hoechst Ag
Application granted granted Critical
Publication of EG18128A publication Critical patent/EG18128A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
EG88/87A 1986-02-20 1987-02-18 Process for preparation of substituted thienoimidazole derivatives and their use as inhibitors of gastric acid secretion EG18128A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19863605395 DE3605395A1 (de) 1986-02-20 1986-02-20 Substituierte thienoimidazol-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische zubereitungen und ihre verwendung als magensaeuresekretionshemmer
DE19863623683 DE3623683A1 (de) 1986-07-12 1986-07-12 Substituierte thienoimidazol-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische zubereitungen und ihre verwendung als magensaeuresekretionshemmer
DE19873700436 DE3700436A1 (de) 1987-01-09 1987-01-09 Substituierte thienoimidazol-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische zubereitungen und ihre verwendung als magensaeuresekretionshemmer

Publications (1)

Publication Number Publication Date
EG18128A true EG18128A (en) 1992-08-30

Family

ID=27194035

Family Applications (1)

Application Number Title Priority Date Filing Date
EG88/87A EG18128A (en) 1986-02-20 1987-02-18 Process for preparation of substituted thienoimidazole derivatives and their use as inhibitors of gastric acid secretion

Country Status (22)

Country Link
US (1) US4845118A (xx)
EP (1) EP0234485B1 (xx)
JP (1) JPH0633275B2 (xx)
KR (2) KR950001025B1 (xx)
CN (1) CN1021911C (xx)
AR (1) AR246739A1 (xx)
AU (1) AU590390B2 (xx)
CA (1) CA1337197C (xx)
DE (1) DE3777855D1 (xx)
DK (1) DK85087A (xx)
EG (1) EG18128A (xx)
ES (1) ES2032394T3 (xx)
FI (1) FI870672A (xx)
GR (1) GR3004765T3 (xx)
HU (1) HU197330B (xx)
IE (1) IE60572B1 (xx)
IL (1) IL81609A (xx)
MA (1) MA20880A1 (xx)
NO (1) NO170155C (xx)
NZ (1) NZ219320A (xx)
PT (1) PT84319B (xx)
TN (1) TNSN87024A1 (xx)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI861772A (fi) * 1985-05-07 1986-11-08 Chemie Linz Ag Nya tieno(2,3-d)imidazolderivat och foerfarande for deras framstaellning.
CA1256109A (en) * 1986-09-10 1989-06-20 Franz Rovenszky Process for the preparation of derivatives of 4, 5-dihydrooxazoles
US4912101A (en) * 1987-03-13 1990-03-27 Fujirebio Kabushiki Kaisha 4-aminomethyl-pyridyl-2-oxy derivatives having anti-ulcer activity
DE3723327A1 (de) * 1987-07-15 1989-02-02 Hoechst Ag Substituierte thienoimidazol-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische zubereitungen und ihre verwendung als magensaeuresekretionshemmer, magenschutzmittel sowie als medikament gegen intestinale entzuendungen
AU622866B2 (en) * 1987-07-21 1992-04-30 Hoechst Aktiengesellschaft Substituted thienoimidazole derivatives, processes for their preparation, pharmaceutical formulations containing them and their use as gastric acid secretion inhibitors
IT1222412B (it) * 1987-07-31 1990-09-05 Chiesi Farma Spa Tiometil e sulfinil metil derivati ad azione antisecretiva acida gastrica,loro procedimento di preparazione e composizioni farmaceutiche che li contengono
DE3827276A1 (de) * 1987-08-15 1989-03-23 Hoechst Ag Substituierte thienoimidazol-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische zubereitungen und ihre verwendung als magensaeuresekretionshemmer
ATE110078T1 (de) * 1987-11-13 1994-09-15 Hoechst Ag Substituierte thienoimidazol-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische zubereitungen und ihre verwendung als magensäuresekretionshemmer.
FI885878A (fi) * 1987-12-22 1989-06-23 Hoechst Ag Substituerade tienoimidazolderivat, foerfarande foer deras framstaellning, dessa innehaollande farmaceutiska kompositioner och deras anvaendning som inhibitorer vid avsoendring av magsyra.
US6852739B1 (en) 1999-02-26 2005-02-08 Nitromed Inc. Methods using proton pump inhibitors and nitric oxide donors
CN1361683A (zh) 1999-06-07 2002-07-31 比克·古尔顿·劳姆贝尔格化学公司 含有一种对酸不稳定的活性化合物的新型制剂和药物剂型
US8048917B2 (en) 2005-04-06 2011-11-01 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US7232924B2 (en) 2001-06-11 2007-06-19 Xenoport, Inc. Methods for synthesis of acyloxyalkyl derivatives of GABA analogs
US6818787B2 (en) 2001-06-11 2004-11-16 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US7186855B2 (en) 2001-06-11 2007-03-06 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
CA2493618A1 (en) 2002-08-01 2004-02-12 Nitromed, Inc. Nitrosated proton pump inhibitors, compositions and methods of use
US8802139B2 (en) * 2003-06-26 2014-08-12 Intellipharmaceutics Corp. Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient
PL1746980T3 (pl) * 2004-05-07 2012-03-30 Nycomed Gmbh Farmaceutyczna postać dawkowania zawierająca peletki i sposób jej wytwarzania
US8394409B2 (en) 2004-07-01 2013-03-12 Intellipharmaceutics Corp. Controlled extended drug release technology
US10624858B2 (en) 2004-08-23 2020-04-21 Intellipharmaceutics Corp Controlled release composition using transition coating, and method of preparing same
US10064828B1 (en) 2005-12-23 2018-09-04 Intellipharmaceutics Corp. Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems
WO2007112581A1 (en) 2006-04-03 2007-10-11 Isa Odidi Controlled release delivery device comprising an organosol coat
US10960077B2 (en) 2006-05-12 2021-03-30 Intellipharmaceutics Corp. Abuse and alcohol resistant drug composition
WO2008057802A2 (en) 2006-10-27 2008-05-15 The Curators Of The University Of Missouri Compositions comprising at least one acid labile proton pump inhibiting agents, optionally other pharmaceutically active agents and methods of using same
US20080194307A1 (en) * 2007-02-13 2008-08-14 Jeff Sanger Sports-based game of chance
CN101980700A (zh) 2008-02-20 2011-02-23 密苏里大学董事会 包含奥美拉唑和兰索拉唑以及缓冲剂的组合的组合物及其使用方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3132167A1 (de) 1981-08-14 1983-03-03 Hoechst Ag, 6000 Frankfurt "5(6)-phenylsulfonyloxy-benzimidazolderivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische zubereitungen und ihre verwendung gegen leberegel"
SE416649B (sv) 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
SE7804231L (sv) 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
US4472409A (en) 1981-11-05 1984-09-18 Byk Gulden Lomberg Chemische Fabrik Gesellschaft Mit Beschrankter Haftung 2-Pyridylmethyl thio(sulfinyl)benzimidazoles with gastric acid secretion inhibiting effects
SE8300736D0 (sv) * 1983-02-11 1983-02-11 Haessle Ab Novel pharmacologically active compounds
US4575554A (en) * 1983-12-05 1986-03-11 The Upjohn Company Substituted 2-pyridylmethylthio- and sulfinyl-benzimidazoles as gastric antisecretory agents
GB8417171D0 (en) * 1984-07-05 1984-08-08 Beecham Group Plc Compounds
AU568441B2 (en) 1984-09-24 1987-12-24 Upjohn Company, The 2-(pyridylalkenesulfinyl) benzimidazole derivatives
FI861772A (fi) * 1985-05-07 1986-11-08 Chemie Linz Ag Nya tieno(2,3-d)imidazolderivat och foerfarande for deras framstaellning.
WO1987005296A1 (en) * 1986-03-07 1987-09-11 Pfizer Inc. 2-[(2-pyridyl)methylsulfinyl]thienoimidazoles and related compounds as antiulcer agents

Also Published As

Publication number Publication date
NO870666L (no) 1987-08-21
KR950001025B1 (ko) 1995-02-07
IL81609A0 (en) 1987-09-16
JPH0633275B2 (ja) 1994-05-02
US4845118A (en) 1989-07-04
CN1021911C (zh) 1993-08-25
PT84319A (de) 1987-03-01
NO170155C (no) 1992-09-16
AU590390B2 (en) 1989-11-02
GR3004765T3 (xx) 1993-04-28
NO870666D0 (no) 1987-02-19
ES2032394T3 (es) 1993-02-16
KR870007934A (ko) 1987-09-23
NZ219320A (en) 1990-06-26
JPS62198683A (ja) 1987-09-02
HUT44255A (en) 1988-02-29
AU6906687A (en) 1987-08-27
NO170155B (no) 1992-06-09
EP0234485B1 (de) 1992-04-01
TNSN87024A1 (fr) 1990-01-01
IL81609A (en) 1994-10-21
PT84319B (pt) 1989-09-14
MA20880A1 (fr) 1987-10-01
KR890009937A (ko) 1989-08-05
DK85087D0 (da) 1987-02-19
FI870672A (fi) 1987-08-21
EP0234485A1 (de) 1987-09-02
AR246739A1 (es) 1994-09-30
IE60572B1 (en) 1994-07-27
DK85087A (da) 1987-08-21
HU197330B (en) 1989-03-28
DE3777855D1 (de) 1992-05-07
FI870672A0 (fi) 1987-02-18
CN87100719A (zh) 1987-09-09
CA1337197C (en) 1995-10-03
IE870421L (en) 1987-08-20

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