AR222828A1 - Procedimiento para la preparacion de 2,3,4,5-tetrahidro-6-feniltio-1h-3-benzazepinas y sus sales - Google Patents
Procedimiento para la preparacion de 2,3,4,5-tetrahidro-6-feniltio-1h-3-benzazepinas y sus salesInfo
- Publication number
- AR222828A1 AR222828A1 AR277218A AR27721879A AR222828A1 AR 222828 A1 AR222828 A1 AR 222828A1 AR 277218 A AR277218 A AR 277218A AR 27721879 A AR27721879 A AR 27721879A AR 222828 A1 AR222828 A1 AR 222828A1
- Authority
- AR
- Argentina
- Prior art keywords
- feniltio
- benzazepinas
- tetrahidro
- salts
- procedure
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
- C07C41/22—Preparation of ethers by reactions not forming ether-oxygen bonds by introduction of halogens; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
- C07C41/26—Preparation of ethers by reactions not forming ether-oxygen bonds by introduction of hydroxy or O-metal groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic System
- C07F5/02—Boron compounds
- C07F5/022—Boron compounds without C-boron linkages
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US92261378A | 1978-07-07 | 1978-07-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR222828A1 true AR222828A1 (es) | 1981-06-30 |
Family
ID=25447325
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AR277218A AR222828A1 (es) | 1978-07-07 | 1979-07-06 | Procedimiento para la preparacion de 2,3,4,5-tetrahidro-6-feniltio-1h-3-benzazepinas y sus sales |
Country Status (24)
| Country | Link |
|---|---|
| EP (2) | EP0007070B1 (ja) |
| JP (1) | JPS5511584A (ja) |
| AR (1) | AR222828A1 (ja) |
| AU (1) | AU525789B2 (ja) |
| CA (1) | CA1115271A (ja) |
| CS (1) | CS213381B2 (ja) |
| DD (1) | DD147355A5 (ja) |
| DE (1) | DE2964530D1 (ja) |
| DK (1) | DK156001C (ja) |
| ES (3) | ES482276A1 (ja) |
| FI (1) | FI67215C (ja) |
| GR (1) | GR69675B (ja) |
| HU (1) | HU179315B (ja) |
| IE (1) | IE48654B1 (ja) |
| IL (1) | IL57532A (ja) |
| IT (1) | IT1193190B (ja) |
| JO (1) | JO1273B1 (ja) |
| NO (1) | NO152213C (ja) |
| NZ (1) | NZ190745A (ja) |
| PH (1) | PH15754A (ja) |
| PL (1) | PL216908A1 (ja) |
| PT (1) | PT69855A (ja) |
| SU (1) | SU1029827A3 (ja) |
| ZA (1) | ZA792785B (ja) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3119874A1 (de) | 1981-05-19 | 1982-12-09 | Dr. Karl Thomae Gmbh, 7950 Biberach | "benzazepinderivate, ihre herstellung und ihre verwendung als arzneimittel" |
| US4469634A (en) * | 1982-07-29 | 1984-09-04 | Smithkline Beckman Corporation | Allyloxy- and allylthio-2,3,4,5-tetrahydro-1H-3-benzazepines |
| US4652642A (en) * | 1984-08-23 | 1987-03-24 | Smithkline Beckman Corporation | Azidobenzazepines |
| US4683229A (en) * | 1986-03-17 | 1987-07-28 | Smithkline Beckman Corporation | 6-halo-9-alkenyleneoxy-3-alkyl-2,3,4,5-tetrahydro-(1H-3)-benzazepines and their use as selective alpha-adrenergic receptor antagonists |
| US6384079B1 (en) | 1986-12-23 | 2002-05-07 | Tristrata Technology, Incorporated | Compositions comprising 2-hydroxycarboxylic acids and related compounds, and methods for alleviating signs of dermatological aging |
| US5942250A (en) * | 1986-12-23 | 1999-08-24 | Tristrata Technology, Inc. | Compositions and methods for enhancing the topical effects of sunscreen agents |
| GB9119467D0 (en) * | 1991-09-12 | 1991-10-23 | Smithkline Beecham Corp | Chemical compounds |
| GB9708805D0 (en) | 1997-05-01 | 1997-06-25 | Smithkline Beecham Plc | Compounds |
| GB9810876D0 (en) | 1998-05-20 | 1998-07-22 | Smithkline Beecham Plc | Compounds |
| SK4782001A3 (en) | 1998-10-08 | 2001-11-06 | Smithkline Beecham Plc | Tetrahydrobenzazepine derivatives useful as modulators of dopamine d3 receptors (antipsychotic agents) |
| US6953787B2 (en) | 2002-04-12 | 2005-10-11 | Arena Pharmaceuticals, Inc. | 5HT2C receptor modulators |
| WO2004031181A1 (en) * | 2002-10-07 | 2004-04-15 | Glaxo Group Limited | Sulfonamide derivatives as antipsychotic agents |
| HUE028976T2 (en) | 2003-06-17 | 2017-02-28 | Arena Pharm Inc | 8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride |
| EA016558B1 (ru) | 2003-06-17 | 2012-05-30 | Арена Фармасьютикалз, Инк. | Производные бензазепина, используемые для лечения заболеваний, ассоциированных с 5-ht-рецептором |
| EA011011B1 (ru) * | 2004-02-25 | 2008-12-30 | Эли Лилли Энд Компани | 6-ЗАМЕЩЁННЫЕ 2,3,4,5-ТЕТРАГИДРО-1H-БЕНЗО[d]АЗЕПИНЫ В КАЧЕСТВЕ АГОНИСТОВ РЕЦЕПТОРОВ 5-HT |
| JP5270167B2 (ja) | 2004-12-21 | 2013-08-21 | アリーナ ファーマシューティカルズ， インコーポレイテッド | （ｒ）−８−クロロ−１−メチル−２，３，４，５−テトラヒドロ−１ｈ−３−ベンザゼピン塩酸塩の結晶形 |
| CN102631349A (zh) | 2004-12-23 | 2012-08-15 | 艾尼纳制药公司 | 5HT2c受体调节剂组合物和使用方法 |
| JP5199997B2 (ja) | 2006-04-03 | 2013-05-15 | アリーナ ファーマシューティカルズ， インコーポレイテッド | ８−クロロ−１−メチル−２，３，４，５−テトラヒドロ−１ｈ−３−ベンズアゼピンおよびこれに関連する中間体を調製するためのプロセス |
| CN101547892B (zh) | 2006-12-05 | 2014-08-20 | 艾尼纳制药公司 | 制备(r)-8-氯-1-甲基-2,3,4,5-四氢-1h-3-苯并氮杂卓的方法和其中间体 |
| JP5491421B2 (ja) | 2008-03-04 | 2014-05-14 | アリーナ ファーマシューティカルズ， インコーポレイテッド | ５−ｈｔ２ｃアゴニストである（ｒ）−８−クロロ−１−メチル−２，３，４，５−テトラヒドロ−１ｈ−３−ベンゾアゼピンに関連する中間体の調製のためのプロセス |
| WO2010148207A2 (en) | 2009-06-18 | 2010-12-23 | Arena Pharmaceuticals, Inc. | Processes for the preparation of 5-ht2c receptor agonists |
| WO2011153206A1 (en) | 2010-06-02 | 2011-12-08 | Arena Pharmaceuticals, Inc. | Processes for the preparation of 5-ht2c receptor agonists |
| US8999970B2 (en) | 2010-09-01 | 2015-04-07 | Arena Pharmaceuticals, Inc. | Administration of an anti-obesity compound to individuals with renal impairment |
| SG188362A1 (en) | 2010-09-01 | 2013-04-30 | Arena Pharm Inc | Modified-release dosage forms of 5-ht2c agonists useful for weight management |
| SG10201506870PA (en) | 2010-09-01 | 2015-10-29 | Arena Pharm Inc | Salts of lorcaserin with optically active acids |
| EP2611433A2 (en) | 2010-09-01 | 2013-07-10 | Arena Pharmaceuticals, Inc. | Non-hygroscopic salts of 5-ht2c agonists |
| KR20150070249A (ko) | 2012-10-09 | 2015-06-24 | 아레나 파마슈티칼스, 인크. | 체중 관리 방법 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2520264A (en) * | 1947-08-26 | 1950-08-29 | Maltbie Lab Inc | Substituted 3, 1-benz-2, 3, 4, 5-tetrahydroazepines |
| US3483185A (en) * | 1966-08-16 | 1969-12-09 | American Home Prod | N-substituted 2,3,4,5-tetrahydro-1h-3-benzazepines |
| CA974989A (en) * | 1968-03-11 | 1975-09-23 | Wallace And Tiernan Inc. | Process for preparing 1,2,4,5-tetrahydro-3h,3-benzazepines and products obtained thereby |
| US3671519A (en) * | 1969-07-14 | 1972-06-20 | American Home Prod | N-substituted 2,3,4,5,-tetrahydro-1h-3-benzazepines |
| US3752892A (en) | 1970-03-11 | 1973-08-14 | Ciba Geigy Corp | Anorexigenic tetrahydrobenzazepine derivative method and composition thereof |
| US3716639A (en) | 1970-03-11 | 1973-02-13 | Ciba Geigy Corp | Anorexigenic tetrahydrobenzazepines |
| US4111957A (en) * | 1977-02-02 | 1978-09-05 | Smithkline Corporation | Substituted 1-thienyl and furyl-2,3,4,5-tetrahydro-1H-3-benzazepine compounds |
| US4108989A (en) * | 1977-04-01 | 1978-08-22 | Smithkline Corporation | 2,3,4,5-tetrahydro-1h-3-benzazepine-7,8-diones |
-
1979
- 1979-06-05 ZA ZA792785A patent/ZA792785B/xx unknown
- 1979-06-11 IL IL57532A patent/IL57532A/xx unknown
- 1979-06-15 NZ NZ190745A patent/NZ190745A/xx unknown
- 1979-06-28 JP JP8252779A patent/JPS5511584A/ja active Granted
- 1979-07-02 PT PT69855A patent/PT69855A/pt unknown
- 1979-07-02 CS CS794635A patent/CS213381B2/cs unknown
- 1979-07-02 PH PH22728A patent/PH15754A/en unknown
- 1979-07-02 DK DK278379A patent/DK156001C/da not_active IP Right Cessation
- 1979-07-03 GR GR59498A patent/GR69675B/el unknown
- 1979-07-03 CA CA331,022A patent/CA1115271A/en not_active Expired
- 1979-07-03 AU AU48613/79A patent/AU525789B2/en not_active Ceased
- 1979-07-04 EP EP79102279A patent/EP0007070B1/en not_active Expired
- 1979-07-04 EP EP82105188A patent/EP0080012B1/en not_active Expired
- 1979-07-04 DE DE7979102279T patent/DE2964530D1/de not_active Expired
- 1979-07-05 FI FI792125A patent/FI67215C/fi not_active IP Right Cessation
- 1979-07-05 HU HU79SI1705A patent/HU179315B/hu unknown
- 1979-07-06 PL PL21690879A patent/PL216908A1/xx unknown
- 1979-07-06 ES ES482276A patent/ES482276A1/es not_active Expired
- 1979-07-06 NO NO792267A patent/NO152213C/no unknown
- 1979-07-06 ES ES482282A patent/ES482282A1/es not_active Expired
- 1979-07-06 DD DD79214179A patent/DD147355A5/de unknown
- 1979-07-06 SU SU792783746A patent/SU1029827A3/ru active
- 1979-07-06 ES ES482281A patent/ES482281A1/es not_active Expired
- 1979-07-06 IT IT24165/79A patent/IT1193190B/it active
- 1979-07-06 AR AR277218A patent/AR222828A1/es active
- 1979-07-07 JO JO19791273A patent/JO1273B1/en active
- 1979-08-08 IE IE1276/79A patent/IE48654B1/en unknown
Also Published As
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