AR125753A1 - Anticuerpos anti-tigit, anticuerpos anti-cd96 y métodos de uso de estos - Google Patents

Anticuerpos anti-tigit, anticuerpos anti-cd96 y métodos de uso de estos

Info

Publication number
AR125753A1
AR125753A1 ARP220101162A ARP220101162A AR125753A1 AR 125753 A1 AR125753 A1 AR 125753A1 AR P220101162 A ARP220101162 A AR P220101162A AR P220101162 A ARP220101162 A AR P220101162A AR 125753 A1 AR125753 A1 AR 125753A1
Authority
AR
Argentina
Prior art keywords
antibodies
tigit
methods
molecules
multispecific
Prior art date
Application number
ARP220101162A
Other languages
English (en)
Spanish (es)
Inventor
Dhan Sidhartha Chand
Zahra Jawad
Olga Ignatovich
Nicola Anne Ramsay
Spencer Campbell
Beth Wensley
Emmanuel Cyrille Pascal Briend
K Mark Bushell
Benjamin Maxime Morin
Veronica Franciszka Ilkow
Original Assignee
Agenus Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agenus Inc filed Critical Agenus Inc
Publication of AR125753A1 publication Critical patent/AR125753A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/32Immunoglobulins specific features characterized by aspects of specificity or valency specific for a neo-epitope on a complex, e.g. antibody-antigen or ligand-receptor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
ARP220101162A 2021-05-04 2022-05-03 Anticuerpos anti-tigit, anticuerpos anti-cd96 y métodos de uso de estos AR125753A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US202163201537P 2021-05-04 2021-05-04

Publications (1)

Publication Number Publication Date
AR125753A1 true AR125753A1 (es) 2023-08-09

Family

ID=83933041

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP220101162A AR125753A1 (es) 2021-05-04 2022-05-03 Anticuerpos anti-tigit, anticuerpos anti-cd96 y métodos de uso de estos

Country Status (16)

Country Link
US (2) US11718669B2 (https=)
EP (1) EP4333893A4 (https=)
JP (1) JP2024516843A (https=)
KR (1) KR20240006054A (https=)
CN (1) CN117425494A (https=)
AR (1) AR125753A1 (https=)
AU (1) AU2022271331A1 (https=)
BR (1) BR112023022319A2 (https=)
CA (1) CA3217289A1 (https=)
CL (1) CL2023003244A1 (https=)
CO (1) CO2023016037A2 (https=)
IL (1) IL308157A (https=)
MX (1) MX2023013078A (https=)
PE (1) PE20240369A1 (https=)
TW (1) TW202304965A (https=)
WO (1) WO2022236276A2 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR125753A1 (es) 2021-05-04 2023-08-09 Agenus Inc Anticuerpos anti-tigit, anticuerpos anti-cd96 y métodos de uso de estos
WO2025188697A1 (en) * 2024-03-04 2025-09-12 Agenus Inc. Methods of treating cancer using anti-cd96/anti-tigit antibodies and combination therapies

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Also Published As

Publication number Publication date
AU2022271331A1 (en) 2023-10-26
EP4333893A2 (en) 2024-03-13
BR112023022319A2 (pt) 2024-02-20
CA3217289A1 (en) 2022-11-10
CO2023016037A2 (es) 2023-11-30
MX2023013078A (es) 2023-11-16
US12479913B2 (en) 2025-11-25
WO2022236276A2 (en) 2022-11-10
US20230014036A1 (en) 2023-01-19
JP2024516843A (ja) 2024-04-17
TW202304965A (zh) 2023-02-01
US20240141039A1 (en) 2024-05-02
CN117425494A (zh) 2024-01-19
EP4333893A4 (en) 2025-06-18
AU2022271331A9 (en) 2023-11-09
WO2022236276A3 (en) 2023-01-19
IL308157A (en) 2024-01-01
PE20240369A1 (es) 2024-03-04
CL2023003244A1 (es) 2024-04-19
US11718669B2 (en) 2023-08-08
KR20240006054A (ko) 2024-01-12

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