BR112023022319A2 - Anticorpos anti-tigit, anticorpos anti-cd96 e métodos de uso dos mesmos - Google Patents
Anticorpos anti-tigit, anticorpos anti-cd96 e métodos de uso dos mesmosInfo
- Publication number
- BR112023022319A2 BR112023022319A2 BR112023022319A BR112023022319A BR112023022319A2 BR 112023022319 A2 BR112023022319 A2 BR 112023022319A2 BR 112023022319 A BR112023022319 A BR 112023022319A BR 112023022319 A BR112023022319 A BR 112023022319A BR 112023022319 A2 BR112023022319 A2 BR 112023022319A2
- Authority
- BR
- Brazil
- Prior art keywords
- antibodies
- tigit
- methods
- multispecific molecules
- human
- Prior art date
Links
- 101100369641 Mus musculus Tigit gene Proteins 0.000 abstract 4
- 239000013604 expression vector Substances 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/32—Immunoglobulins specific features characterized by aspects of specificity or valency specific for a neo-epitope on a complex, e.g. antibody-antigen or ligand-receptor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
anticorpos anti-tigit, anticorpos anti-cd96 e métodos de uso dos mesmos. a presente invenção refere-se moléculas multiespecíficas que se ligam especificamente a cd96 (por exemplo, cd96 humana) e/ou tigit (por exemplo, tigit humano) e anticorpos isolados que se ligam especificamente a tigit (por exemplo, tigit humano). também são fornecidas composições farmacêuticas compreendendo essas moléculas multiespecíficas e anticorpos, ácidos nucleicos que codificam essas moléculas multiespecíficas e anticorpos, vetores de expressão e células hospedeiras para produzir essas moléculas multiespecíficas e anticorpos, e métodos de tratamento de um indivíduo usando essas moléculas multiespecíficas e anticorpos.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163201537P | 2021-05-04 | 2021-05-04 | |
| PCT/US2022/072099 WO2022236276A2 (en) | 2021-05-04 | 2022-05-04 | Anti-tigit antibodies, anti-cd96 antibodies, and methods of use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112023022319A2 true BR112023022319A2 (pt) | 2024-02-20 |
Family
ID=83933041
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112023022319A BR112023022319A2 (pt) | 2021-05-04 | 2022-05-04 | Anticorpos anti-tigit, anticorpos anti-cd96 e métodos de uso dos mesmos |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US11718669B2 (pt) |
| EP (1) | EP4333893A2 (pt) |
| JP (1) | JP2024516843A (pt) |
| KR (1) | KR20240006054A (pt) |
| CN (1) | CN117425494A (pt) |
| AR (1) | AR125753A1 (pt) |
| AU (1) | AU2022271331A1 (pt) |
| BR (1) | BR112023022319A2 (pt) |
| CA (1) | CA3217289A1 (pt) |
| CL (1) | CL2023003244A1 (pt) |
| CO (1) | CO2023016037A2 (pt) |
| IL (1) | IL308157A (pt) |
| MX (1) | MX2023013078A (pt) |
| PE (1) | PE20240369A1 (pt) |
| TW (1) | TW202304965A (pt) |
| WO (1) | WO2022236276A2 (pt) |
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-
2022
- 2022-05-03 AR ARP220101162A patent/AR125753A1/es unknown
- 2022-05-03 TW TW111116719A patent/TW202304965A/zh unknown
- 2022-05-04 BR BR112023022319A patent/BR112023022319A2/pt unknown
- 2022-05-04 IL IL308157A patent/IL308157A/en unknown
- 2022-05-04 AU AU2022271331A patent/AU2022271331A1/en active Pending
- 2022-05-04 WO PCT/US2022/072099 patent/WO2022236276A2/en active Application Filing
- 2022-05-04 MX MX2023013078A patent/MX2023013078A/es unknown
- 2022-05-04 EP EP22799792.1A patent/EP4333893A2/en active Pending
- 2022-05-04 PE PE2023003002A patent/PE20240369A1/es unknown
- 2022-05-04 CA CA3217289A patent/CA3217289A1/en active Pending
- 2022-05-04 JP JP2023568081A patent/JP2024516843A/ja active Pending
- 2022-05-04 KR KR1020237041635A patent/KR20240006054A/ko unknown
- 2022-05-04 CN CN202280040311.3A patent/CN117425494A/zh active Pending
- 2022-08-10 US US17/818,840 patent/US11718669B2/en active Active
-
2023
- 2023-06-13 US US18/333,882 patent/US20240141039A1/en active Pending
- 2023-11-02 CL CL2023003244A patent/CL2023003244A1/es unknown
- 2023-11-23 CO CONC2023/0016037A patent/CO2023016037A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TW202304965A (zh) | 2023-02-01 |
| CO2023016037A2 (es) | 2023-11-30 |
| EP4333893A2 (en) | 2024-03-13 |
| WO2022236276A2 (en) | 2022-11-10 |
| KR20240006054A (ko) | 2024-01-12 |
| CN117425494A (zh) | 2024-01-19 |
| PE20240369A1 (es) | 2024-03-04 |
| MX2023013078A (es) | 2023-11-16 |
| CL2023003244A1 (es) | 2024-04-19 |
| AU2022271331A1 (en) | 2023-10-26 |
| US11718669B2 (en) | 2023-08-08 |
| AU2022271331A9 (en) | 2023-11-09 |
| IL308157A (en) | 2024-01-01 |
| US20240141039A1 (en) | 2024-05-02 |
| CA3217289A1 (en) | 2022-11-10 |
| US20230014036A1 (en) | 2023-01-19 |
| WO2022236276A3 (en) | 2023-01-19 |
| AR125753A1 (es) | 2023-08-09 |
| JP2024516843A (ja) | 2024-04-17 |
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